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Advances in neurotoxicology最新文献

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Inflammatory mechanisms of abused drugs 滥用药物的炎症机制
Advances in neurotoxicology Pub Date : 2019-01-01 DOI: 10.1016/BS.ANT.2018.10.006
C. M. Mitchell, Omar El Jordi, B. Yamamoto
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引用次数: 2
The role of neuroinflammation in developmental neurotoxicity, tackling complexity in children's exposures and outcomes 神经炎症在发育神经毒性中的作用，解决儿童暴露和结果的复杂性
Advances in neurotoxicology Pub Date : 2019-01-01 DOI: 10.1016/BS.ANT.2018.10.008
A. D’Angiulli
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引用次数: 3
Overview of peripheral and central inflammatory responses and their contribution to neurotoxicity 外周和中枢炎症反应的概述及其对神经毒性的贡献
Advances in neurotoxicology Pub Date : 2019-01-01 DOI: 10.1016/BS.ANT.2018.10.001
N. Filipov
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引用次数: 5
An introduction to innate immunity in the central nervous system 介绍中枢神经系统的先天免疫
Advances in neurotoxicology Pub Date : 2019-01-01 DOI: 10.1016/BS.ANT.2018.10.002
G. Harry, G. Childers, C. McPherson
{"title":"An introduction to innate immunity in the central nervous system","authors":"G. Harry, G. Childers, C. McPherson","doi":"10.1016/BS.ANT.2018.10.002","DOIUrl":"https://doi.org/10.1016/BS.ANT.2018.10.002","url":null,"abstract":"","PeriodicalId":72100,"journal":{"name":"Advances in neurotoxicology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/BS.ANT.2018.10.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54048724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Blood-brain barrier at the interface of air pollution-associated neurotoxicity and neuroinflammation 空气污染相关的神经毒性和神经炎症界面的血脑屏障
Advances in neurotoxicology Pub Date : 2019-01-01 DOI: 10.1016/BS.ANT.2018.10.010
T. Young, K. Zychowski, J. L. Denson, M. Campen
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引用次数: 5
Role of neuroinflammation in ethanol neurotoxicity 神经炎症在乙醇神经毒性中的作用
Advances in neurotoxicology Pub Date : 2019-01-01 DOI: 10.1016/BS.ANT.2018.10.009
C. Guerri, M. Pascual
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引用次数: 1
Neurodevelopmental Effects of Mercury. 汞对神经发育的影响。
Advances in neurotoxicology Pub Date : 2018-01-01 Epub Date: 2018-05-24 DOI: 10.1016/bs.ant.2018.03.005
Cláudia S Oliveira, Pablo A Nogara, Daniel M P Ardisson-Araújo, Michael Aschner, João B T Rocha, José G Dórea
{"title":"Neurodevelopmental Effects of Mercury.","authors":"Cláudia S Oliveira, Pablo A Nogara, Daniel M P Ardisson-Araújo, Michael Aschner, João B T Rocha, José G Dórea","doi":"10.1016/bs.ant.2018.03.005","DOIUrl":"10.1016/bs.ant.2018.03.005","url":null,"abstract":"<p><p>The toxicology of mercury (Hg) is of concern since this metal is ubiquitously distributed in the environment, and living organisms are routinely exposed to Hg at low to high levels. The toxic effects of Hg are well studied and it is known that they may differ depending on the Hg chemical species. In this chapter, we emphasize the neurotoxic effects of Hg during brain development. The immature brain is more susceptible to Hg exposure, since all the Hg chemical forms, not only the organic ones, can harm it. The possible consequences of Hg exposure during the early stages of development, the additive effects with other co-occurring neurotoxicants, and the known mechanisms of action and targets will be addressed in this chapter.</p>","PeriodicalId":72100,"journal":{"name":"Advances in neurotoxicology","volume":"2 ","pages":"27-86"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188190/pdf/nihms-1580310.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37882913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metals and Circadian Rhythms. 金属和昼夜节律。
Advances in neurotoxicology Pub Date : 2017-01-01 Epub Date: 2017-09-01 DOI: 10.1016/bs.ant.2017.07.003
Nancy L Parmalee, Michael Aschner
{"title":"Metals and Circadian Rhythms.","authors":"Nancy L Parmalee,&nbsp;Michael Aschner","doi":"10.1016/bs.ant.2017.07.003","DOIUrl":"https://doi.org/10.1016/bs.ant.2017.07.003","url":null,"abstract":"<p><p>Circadian rhythms describe the behavioral and physiological changes that occur in living organisms in order to attune to a 24 hour cycle of day and night. The most striking aspect of circadian function is the sleep-wake cycle, however many other physiological processes are regulated in 24 hour oscillations, including blood pressure, body temperature, appetite, urine production, and the transcription and translation of thousands of circadian dependent genes. Circadian disruption and sleep disorders are strongly connected to neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, and Huntington's disease as well as others. Metal exposures have been implicated in neurodegenerative diseases, in some cases involving metals that are essential micronutrients but are toxic at high levels of exposure (such as manganese, copper, and zinc), and in other cases involving metals that have no biological role but are toxic to living systems (such as lead, mercury, and aluminum). In this review, we examine the evidence for circadian and sleep disorders with exposures to these metals and review the literature for possible mechanisms. We suggest that giving the aging population, the prevalence of environmental exposures to metals, and the increasing prevalence of neurodegenerative disease in the aged, more research into the mechanisms of circadian disruption subsequent to metal exposures is warranted.</p>","PeriodicalId":72100,"journal":{"name":"Advances in neurotoxicology","volume":"1 ","pages":"119-130"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.ant.2017.07.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36937059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
The catecholaminergic neurotransmitter system in methylmercury-induced neurotoxicity. 甲基汞诱导的神经毒性中的儿茶酚胺能神经递质系统。
Advances in neurotoxicology Pub Date : 2017-01-01 Epub Date: 2017-09-01 DOI: 10.1016/bs.ant.2017.07.002
Marcelo Farina, Michael Aschner, João Batista Teixeira da Rocha
{"title":"The catecholaminergic neurotransmitter system in methylmercury-induced neurotoxicity.","authors":"Marcelo Farina,&nbsp;Michael Aschner,&nbsp;João Batista Teixeira da Rocha","doi":"10.1016/bs.ant.2017.07.002","DOIUrl":"https://doi.org/10.1016/bs.ant.2017.07.002","url":null,"abstract":"","PeriodicalId":72100,"journal":{"name":"Advances in neurotoxicology","volume":"1 ","pages":"47-81"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.ant.2017.07.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37882523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
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