Advances in geriatric medicine and research最新文献

{"title":"Hematopoietic Stem Cell Metabolism during Stress and Aging.","authors":"Devyani Sharma, Marie-Dominique Filippi","doi":"10.20900/agmr20260018","DOIUrl":"10.20900/agmr20260018","url":null,"abstract":"<p><p>Hematopoietic stem cells (HSCs) support the lifelong production of blood but undergo substantial changes during aging. Aging causes a progressive decline in the repopulation ability of HSC with changes in the proportion of myeloid and lymphoid lineages. Metabolic remodeling is increasingly recognized not only as a consequence of HSC aging but also as an active contributor to age-associated changes in HSC function. Quiescent HSCs have low metabolic activity, in contrast with their highly proliferative progeny. During regeneration, drastic metabolic remodeling enables HSC to exit quiescent and proliferate to sustain blood production for emergency hematopoiesis. Metabolic activity drifts during aging. Changes in glycolysis, mitochondrial activity, and lysosomal functions all contribute to a slow decline of the hematopoietic system. In this review, we focus on the metabolic needs of HSCs, how they control their quiescence and proliferation, and how a metabolic drift contributes to HSC aging.</p>","PeriodicalId":72094,"journal":{"name":"Advances in geriatric medicine and research","volume":"8 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13521646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148842397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Individualized Treatment Approaches for Obstructive Sleep Apnea in Older Adults: Beyond Continuous Positive Airway Pressure.","authors":"Nikhil Jaganathan, Varun Goel, Xiaoyue Liu, Wenzhan Song, Younghoon Kwon, Jeongok Logan, William J Healy","doi":"10.20900/agmr20260020","DOIUrl":"https://doi.org/10.20900/agmr20260020","url":null,"abstract":"<p><p>With an aging population and greater prevalence of metabolic disorders, obstructive sleep apnea (OSA) is increasingly observed in older patients. OSA in older adults often occurs in the setting of various comorbidities, such as cognitive, cardiac, and metabolic dysfunction, placing these patients at greater risk. Continuous positive airway pressure (CPAP) is the first-line treatment for OSA in most patients, but adherence with CPAP decreases with increasing age. Current literature on considerations and efficacy of treatment modalities for OSA in older patients is limited. This narrative review summarizes current evidence on CPAP and non-CPAP therapies of OSA in older adults with particular attention to age-specific differences in clinical presentation, diagnostic challenges, and implications for quality of life. Relevant guidelines, clinical studies, and systematic reviews selected from the PubMed and Cochrane databases through April 2026 were summarized and categorized based on type of therapy. Some non-CPAP alternatives appear promising or effective in selected adults for improving metrics of sleep, quality of life, and mitigating comorbidities, but for geriatric-specific comparative evidence remains limited, indirect, observational, or derived from adults substantially younger than the target population. Lifestyle modifications, positional therapy, and oral appliances may yield benefits in older patients comparable to those seen in their younger counterparts, but age-stratified studies are limited. While pharmacotherapy is an area of emerging study, GLP-1 RAs show significant early potential with multifaceted benefits, although supporting studies have been primarily conducted in middle-aged adults. Hypoglossal nerve stimulation has emerged as a prominent OSA treatment alternative with improved adherence compared to CPAP in in small elderly-specific studies. OSA management in older patients is highly nuanced with multifactorial consideration of polypharmacy, comorbidities, and patient preferences to optimize patient outcomes. Larger-scale, prospective studies specific to older patients are warranted to assess treatment efficacy, adherence, and adverse effects in this population.</p>","PeriodicalId":72094,"journal":{"name":"Advances in geriatric medicine and research","volume":"8 3","pages":"e260020"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13638223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149119084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Initial Feasibility and Criterion Validation of an Electronic, Self-Administered, Geriatric Assessment to Facilitate Fitness-To-Drive Evaluations in Older Adults.","authors":"Luke D Braun, William P Gahan, Johnathon Ehsani, Michelle Duren, Sara Seifert, Louis Barrett, Kevin Kramer, Jeffrey N Keller","doi":"10.20900/agmr20260011","DOIUrl":"10.20900/agmr20260011","url":null,"abstract":"<p><strong>Background: </strong>Geriatric assessments are considered the gold standard for the medical evaluation and management of older adult patients' even though the time required for administration, and additional logistical challenges, has impeded widespread adoption in clinical care.</p><p><strong>Objective: </strong>The current study examines the initial feasibility and criterion validity of a brief, electronic, self-guided (BES) geriatric assessment designed to capture multiple medical and non-medical aspects of a comprehensive geriatric assessment including informing medical fitness-to-drive determinations.</p><p><strong>Methods: </strong>Data was obtained from 49 older adult drivers (34 female, 15 male) aged 50-85. Feasibility was evaluated by determining the ability of older adult drivers to complete the BES geriatric assessment remotely without assistance. Criterion validity was assessed by comparing self-reported responses on the BES geriatric assessment to their responses during a subsequent clinician-led consultation with a geriatrician. Validity was operationalized as concordance (proportion of items requiring no correction) and comprehensiveness (frequency and nature of supplementary details elicited during the clinical interview).</p><p><strong>Results: </strong>Our results support the BES geriatric assessment being a feasible and valid mechanism for the collection of medical and non-medical data related to a comprehensive geriatric assessment used as part of a fitness-to-drive evaluation. All 49 participants successfully completed the BES geriatric assessment without assistance, supporting feasibility of self-administration in this population. Self-reported digital responses demonstrated concordance with clinician-verified data (accuracy: 100%, 95% CI: 92.7%-100%). The geriatrician-led consultation elicited 41 supplementary items across 26 participants (53.1%) that provided additional contextual detail to reported events. All contextual clarifications were consistent with open-ended clinical interviewing, with no contradicted self-reported data reported.</p><p><strong>Conclusions: </strong>The BES geriatric assessment represents a feasible and accurate approach for collecting comprehensive geriatric assessment level data in older adult drivers. This approach has the potential to increase patient access to comprehensive geriatric assessments and streamline medical fitness-to-drive determinations.</p>","PeriodicalId":72094,"journal":{"name":"Advances in geriatric medicine and research","volume":"8 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13332748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148392573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rural Caregivers Bridge the Gap between Older Patients and In-Home Occupational Therapy Video Telehealth: A Qualitative Study.","authors":"Megan E Gately, Dylan E Waller, Matthew C Maynard, Lauren R Moo","doi":"10.20900/agmr20260013","DOIUrl":"10.20900/agmr20260013","url":null,"abstract":"<p><strong>Background: </strong>In-home video telehealth expanded access to services for older rural Veteran patients, yet many require caregiver assistance. Understanding caregivers' experiences is essential to optimizing these encounters.</p><p><strong>Objective: </strong>To explore caregiver perspectives on facilitating in-home occupational therapy video telehealth for older rural Veterans within the US Veterans Health Administration (VHA).</p><p><strong>Methods: </strong>Semi-structured interviews were conducted with rural caregivers (N = 19) from four VHA sites who had assisted an older Veteran patient with in-home video. Interviews focused on caregivers' participation before and during sessions, and perceived benefits and drawbacks of video. We employed directed content analysis utilizing a rapid analytic approach, given the time-pressured nature of our project.</p><p><strong>Results: </strong>Caregivers were predominantly White and female, with an average age of 60; most lived with patients. Five themes emerged: (1) Caregiver Level of Involvement in In-Home Video Telehealth Visits; (2) Experience of Technological Aspects of In-Home Video; (3) Experience of Clinical Aspects of In-Home Video; (4) Beliefs about the Usefulness and Scope of In-Home Video; (5) Recommendations for In-Home Video.</p><p><strong>Conclusions: </strong>In-home video telehealth expands access to rural older patients, relying heavily on caregivers. It works for routine care but has limits and connectivity barriers, requiring improved procedures and infrastructure.</p>","PeriodicalId":72094,"journal":{"name":"Advances in geriatric medicine and research","volume":"8 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13673956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conducting Screenings and Determining Primary Healthcare Provider Follow-Up for Heart, Muscle, and Brain Health in Older Adults at a Community Pharmacy: An Implementation-Oriented Pilot Study.","authors":"Jayme Steig, Jacob Kieser, Ryan McGrath","doi":"10.20900/agmr20260006","DOIUrl":"10.20900/agmr20260006","url":null,"abstract":"<p><strong>Background: </strong>Frequently visited community pharmacies can serve as sites for additional healthcare, including screenings for unknown conditions. Our implementation-oriented pilot study sought to evaluate the proportions of older adults that followed-up with their primary healthcare provider about a positive cardiac arrhythmia, weakness, or cognitive impairment screening performed in a community pharmacy.</p><p><strong>Methods: </strong>A cross-sectional design was used and screenings occurred at a well-visited community pharmacy inside a clinic. Possible cardiac arrhythmias were identified with a mobile electrocardiogram. Weakness status was examined with a hydraulic handgrip dynamometer. A paper-and-pencil based cognitive assessment determined cognitive impairment status. Participants screening positive were advised to visit their healthcare provider, and follow-up for determining if such visits occurred was performed approximately 3-months later.</p><p><strong>Results: </strong>Of the 106 participants, 51 were referred to their healthcare provider for any positive screening. At follow-up, 12 (23.5%) participants reported visiting their primary healthcare provider about the positive screening performed at the community pharmacy.</p><p><strong>Conclusions: </strong>Our implementation-oriented pilot study showed promise for kindling healthcare provider follow-up regarding positive screenings performed at a community pharmacy. Conducting such screenings may reengage patients with their primary healthcare providers when appropriate, and support the identification of unknown conditions.</p>","PeriodicalId":72094,"journal":{"name":"Advances in geriatric medicine and research","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13431257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148671370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Need for Engagement in Stroke Prevention Shared Decision-Making in Older Adults with Atrial Fibrillation and Multimorbidity.","authors":"Hawa O Abu, Jane S Saczynski, Michelle Nabi, Annie Ferris, Mayra Tisminetzky, Jerry H Gurwitz, Kathleen Mazor, Robert J Goldberg, David Dosa, Alok Kapoor, Daniel Matlock, David D McManus","doi":"10.20900/agmr20250016","DOIUrl":"10.20900/agmr20250016","url":null,"abstract":"<p><strong>Aim: </strong>To assess the prevalence of older adults with AF and multimorbidity expressing a need for greater involvement in SDM for stroke prevention and associated patient characteristics.</p><p><strong>Methods: </strong>A prospective cohort study (2016-2018) enrolled patients aged 65 years and older with AF from clinics in MA and Georgia. Participants with one or more chronic conditions were included in this study. To assess patient preferences for greater engagement in SDM, participants on oral anticoagulants were asked at the one-year follow-up if they would like to be more involved in deciding to take an anticoagulant and which oral anticoagulant to use for stroke prevention. Multivariable logistic regression analysis was used to identify patient characteristics associated with preference for more SDM engagement.</p><p><strong>Results: </strong>Among participants (<i>n</i> = 532; mean age: 75 years; 48% women, 87% White), 41% had 1-4 chronic conditions, 40% had 5-7, and 19% had 8 or more. Approximately one-third expressed a preference for both engaging in SDM on anticoagulation initiation and choosing the type of anticoagulant for stroke prevention. After multivariable adjustment, participants who were younger (aged 65-74 years), women, non-White, had less than high school education, higher perceived burden from anticoagulation use, or had fewer comorbidities, were more likely to report the need for greater SDM engagement for stroke prevention.</p><p><strong>Conclusions: </strong>Clinicians should recognize the specific needs of older patients with AF and multimorbidity that seek greater involvement in SDM for stroke prevention. Providing tailored interventions can enhance stroke prevention decision-making in this vulnerable population.</p>","PeriodicalId":72094,"journal":{"name":"Advances in geriatric medicine and research","volume":"7 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12710876/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145783786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From First Slip to Second Setback: Intracranial Injury Risk after Recurrent Falls in Older Adults: A Retrospective Cohort Study.","authors":"Asmaa Namoos, Nicholas Thomson Thomson, Tarek Zaho, Amanda Rudderman, Michel Aboutanos","doi":"10.20900/agmr20250012","DOIUrl":"10.20900/agmr20250012","url":null,"abstract":"<p><strong>Background: </strong>Recurrent falls in older adults are a major public health concern, often resulting in severe injuries such as Intracranial Injuries (ICIs). These injuries increase the risk of cognitive decline, disability, and early mortality. While medications like antihypertensives and antidepressants are essential for managing chronic conditions, they may also contribute to fall-related injury risk.</p><p><strong>Methods: </strong>This retrospective cohort study analyzed data from 3760 adults aged 65 to 89 years at the Virginia Commonwealth University Health System (VCUHS) in 2023. Patients were categorized into two cohorts: those with initial falls (<i>n</i> = 2710) and those with recurrent falls (<i>n</i> = 1050). Demographic variables, medication use, and fall-related ICI outcomes were examined. Incidence, prevalence, and measures of association were calculated. Cox regression models assessed the impact of demographic and clinical predictors on ICI risk.</p><p><strong>Results: </strong>The risk of ICI was 10.4% higher in patients with recurrent falls compared to those with initial falls (HR = 1.104, 95% CI: 0.833-1.463, <i>p</i> = 0.0493). Males were significantly more likely to sustain ICIs (HR = 1.369, 95% CI: 1.054-1.779, <i>p</i> = 0.0186), as were older adults with each additional year of age (HR = 1.021, 95% CI: 1.001-1.041, <i>p</i> = 0.0347). Antihypertensive use nearly doubled the risk of ICI (HR = 1.958, 95% CI: 1.379-2.781, <i>p</i> = 0.0002), and antidepressant use was associated with a 47.1% increase (HR = 1.471, 95% CI: 1.1-1.968, <i>p</i> = 0.0093). Race was not a significant predictor of ICI risk in adjusted models.</p><p><strong>Conclusions: </strong>Recurrent falls were associated with a higher likelihood of ICIs among older adults, particularly in males, those of advanced age, and individuals prescribed antihypertensive or antidepressant medications. These results point to the importance of identifying patients at increased vulnerability and tailoring fall-related care and medication reviews accordingly to help reduce injury severity in this population.</p>","PeriodicalId":72094,"journal":{"name":"Advances in geriatric medicine and research","volume":"7 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12818947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146020745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Weakness Status is Differentially Associated with Time to Diabetes in Americans","authors":"K.-P. Knoll, Yeong Rhee, Natasha Fillmore, Donald A. Jurivich, Justin J Lang, Brenda M. McGrath, Grant R Tomkinson, Ryan McGrath","doi":"10.20900/agmr20240004","DOIUrl":"https://doi.org/10.20900/agmr20240004","url":null,"abstract":"Background : The purpose of this study was to evaluate the associations of (1) individual absolute and body size normalized weakness cut-points, and (2) the collective weakness classifications on time to diabetes in Americans. Methods : We analyzed data from 9577 adults aged at least 50-years from the Health and Retirement Study. Diabetes diagnosis was self-reported. A handgrip dynamometer measured handgrip strength (HGS). Males with HGS <35.5 kg (absolute), <0.45 kg/kg (normalized to body weight), or <1.05 kg/kg/m 2 (normalized","PeriodicalId":72094,"journal":{"name":"Advances in geriatric medicine and research","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141808733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Memory Loss and Missteps: Investigating Fall Risks in Alzheimer's and Dementia Patients.","authors":"Asmaa Namoos, Nicholas Thomson, Sarah Bradley, Amanda Rudderman, Michel Aboutanos","doi":"10.20900/agmr20240005","DOIUrl":"10.20900/agmr20240005","url":null,"abstract":"<p><strong>Background: </strong>Degenerative diseases such as Alzheimer's disease and dementia are significant health concerns among older adults in the United States, contributing substantially to the high incidence of falls in this population. This study aims to investigate the incidence and prevalence of falls among older adults diagnosed with Alzheimer's disease and dementia and explore the association between these conditions and the occurrence of traumatic brain injuries (TBIs).</p><p><strong>Methods: </strong>A retrospective cohort study was conducted using data from 17,000 older adults aged 65 and above, arrived at the hospital with fall related injuries, obtained from the TriNetX network at Virginia Commonwealth University Health System (VCUHS) between January 1, 2019, and December 31, 2023. Data included demographic information, diagnosis codes (ICD-10), and details on falls, Alzheimer's disease, dementia, and TBIs. Descriptive statistics and logistic regression analyses were performed using TriNetX analytical tools.</p><p><strong>Results: </strong>Older adults with Alzheimer's disease (incidence proportion: 3.11%, prevalence: 4.81%) and dementia (incidence proportion: 12.46%, prevalence: 17.06%) had a significantly higher incidence of falls compared to those without these conditions. Females showed a slightly higher incidence of falls than males. Logistic regression analysis indicated that patients with Alzheimer's disease had a reduced risk of TBIs (OR = 0.765, 95% CI: 0.588-0.996, <i>p</i> = 0.047), while those with unspecified dementia had an increased risk (OR = 1.161, 95% CI: 1.002-1.346, <i>p</i> = 0.047).</p><p><strong>Conclusions: </strong>Our study reveals a higher risk of falls and traumatic brain injuries (TBIs) in older adults with dementia compared to those with Alzheimer's disease. These findings underscore the need for targeted fall prevention strategies and educational programs for caregivers.</p>","PeriodicalId":72094,"journal":{"name":"Advances in geriatric medicine and research","volume":"6 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta-Analysis-Based Comparison of Annual Fall Risk between Older Adults with Alzheimer's Disease and Mild Cognitive Impairment.","authors":"Caroline Simpkins, Sara Mahmoudzadeh Khalili, Feng Yang","doi":"10.20900/agmr20240002","DOIUrl":"10.20900/agmr20240002","url":null,"abstract":"<p><strong>Background: </strong>Falls are a primary cause of injuries and hospitalization in older adults. It has been reported that cognitive impairments and dementia can increase fall risk in the older population; however, it remains unknown if fall risk differs among subgroups of dementia. This meta-analysis summarized previous studies reporting the annual fall risk of people with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and compared the fall risk between these two groups of people with dementia.</p><p><strong>Methods: </strong>Thirty-five studies enrolling 7844 older adults with AD or MCI were included. The annual fall prevalence and average number of falls of the included studies were meta-analyzed and compared by random-effects models with inverse variance weights.</p><p><strong>Results: </strong>The annual fall prevalence in people with AD (43.55%) was significantly higher than MCI (35.26%, <i>p</i> < 0.001). A <i>χ</i>² test indicated that the pooled fall prevalence is significantly higher in people with AD than MCI <i>χ</i>² = 158.403, <i>p</i> < 0.001). Additionally, the yearly average number of falls in AD was higher than in MCI (1.30 vs 0.77 falls/person).</p><p><strong>Conclusions: </strong>The results showed that older people with AD experience a higher annual fall prevalence with a larger number of falls than older adults with MCI. The results suggested that the fall risk measurements should be reported separately between people with AD and MCI. The findings could provide preliminary guidance for the identification of individuals with dementia who experience a high fall risk.</p>","PeriodicalId":72094,"journal":{"name":"Advances in geriatric medicine and research","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11081206/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}