Acta Scientiarum. Health Science最新文献_第2页

Effects of water pilates on urinary loss, genital self-image and sexual function of elderly women 水普拉提对老年妇女失尿、生殖器自我形象及性功能的影响

Acta Scientiarum. Health Science Pub Date : 2021-02-11 DOI: 10.4025/ACTASCIHEALTHSCI.V43I1.51900

Deise Iop Tavares, Gessica Bordin Viera Schlemmer, Amanda Santos, Milena Ramila Pivetta, G. T. Arruda, Tamires Daros dos Santos, A. P. Vendrusculo, M. Braz

{"title":"Effects of water pilates on urinary loss, genital self-image and sexual function of elderly women","authors":"Deise Iop Tavares, Gessica Bordin Viera Schlemmer, Amanda Santos, Milena Ramila Pivetta, G. T. Arruda, Tamires Daros dos Santos, A. P. Vendrusculo, M. Braz","doi":"10.4025/ACTASCIHEALTHSCI.V43I1.51900","DOIUrl":"https://doi.org/10.4025/ACTASCIHEALTHSCI.V43I1.51900","url":null,"abstract":"Descriptive, quasi experimental study with pre and post-test, which aimed to investigate the effects of Water Pilates (PA) on urinary incontinence, genital self-image and sexual function of elderly women. The sample consisted of seventeen elderly women aged 60 years or over, from a city in the interior of Rio Grande do Sul. The International Consultation on Incontinence Questionnaire Short Form (ICIQSF) was used as instruments to assess the impact of UI in quality of life and qualify urinary loss, the Female Sexual Function Index (FSFI) to assess sexual function and Female Genital Self-Image Scale (FGSIS) to assess women's perception of their own genitalia. The PA protocol was performed twice a week for 50 minutes performed for eight weeks, totaling 16 sessions. The protocol was divided into warm-up, strengthening exercises and stretching. It was observed that the sample was composed of young elderly women (69.5 ± 5.9 years), overweight and with low FSFI and FGSIS scores. There was no significant change in the mean values before and after the intervention of the ICIQ-SF, FGSIS and FSFI scores. It was concluded that the PA method had no effect on urinary loss, sexual function and genital self-image.","PeriodicalId":7185,"journal":{"name":"Acta Scientiarum. Health Science","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80378502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Influence of Alzheimer’s disease on the relationship between nutritional status and risk of fall 阿尔茨海默病对营养状况与跌倒风险关系的影响

Acta Scientiarum. Health Science Pub Date : 2021-02-11 DOI: 10.4025/ACTASCIHEALTHSCI.V43I1.48747

M. Haskel, Sara C. S. Souza, Danilo Fernandes da Silva, W. C. D. Silva, J. Bonini

{"title":"Influence of Alzheimer’s disease on the relationship between nutritional status and risk of fall","authors":"M. Haskel, Sara C. S. Souza, Danilo Fernandes da Silva, W. C. D. Silva, J. Bonini","doi":"10.4025/ACTASCIHEALTHSCI.V43I1.48747","DOIUrl":"https://doi.org/10.4025/ACTASCIHEALTHSCI.V43I1.48747","url":null,"abstract":"Although malnutrition and risk of falls in the elderly have increased in recent years, uncertainties exist as to whether these conditions are associated after controlling for sociodemographic variables, body composition, metabolic condition, and Alzheimer’s disease (AD). This study aimed to analyze the association between nutritional status and risk of fall in the elderly population. Participants were matched by gender and age, after they had been grouped on the basis of diagnosis of AD. The risk of falls, nutritional status, and mental status were assessed using the Downton Fall Risk Score (FRS), Mini Nutritional Assessment (MNA), and Mini Mental State Evaluation (MMSE), respectively. Logistic regression models adjusted for the main confounders were used in the analyses. Among the 68 elderly individuals studied, participants who were malnourished or at risk of malnutrition were more likely to fall (odds ratio = 8.29; 95% confidence interval = 1.49-46.04) than those with normal nutritional status, regardless of gender, age, education, body composition, and metabolic condition. This association did not remain significant after adjustment for AD, a potential confounder in this association. Malnutrition or its risk was independently associated with high risk of fall; thus, malnutrition should be considered in the prevention of falls among the elderly population.","PeriodicalId":7185,"journal":{"name":"Acta Scientiarum. Health Science","volume":"248 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73527351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cases of leprosy notified in the municipality of Parnaíba, state of Piauí, Brazil, 2007-2016 2007-2016年巴西Piauí州Parnaíba市通报的麻风病病例

Acta Scientiarum. Health Science Pub Date : 2021-02-11 DOI: 10.4025/ACTASCIHEALTHSCI.V43I1.51445

J. Almeida, Maria do Socorro Costa, Paulo Roberto Fagundes da Silva, F. Silva, Gerarlene Ponte Guimarães Santos, Rayla Maria Pontes Guimarães Costa, A. Sardinha, M. R. Branco

{"title":"Cases of leprosy notified in the municipality of Parnaíba, state of Piauí, Brazil, 2007-2016","authors":"J. Almeida, Maria do Socorro Costa, Paulo Roberto Fagundes da Silva, F. Silva, Gerarlene Ponte Guimarães Santos, Rayla Maria Pontes Guimarães Costa, A. Sardinha, M. R. Branco","doi":"10.4025/ACTASCIHEALTHSCI.V43I1.51445","DOIUrl":"https://doi.org/10.4025/ACTASCIHEALTHSCI.V43I1.51445","url":null,"abstract":"This study aimed to describe the epidemiological and clinical characteristics of leprosy cases reported in the municipality of Parnaíba, State of Piauí. This was a cross-sectional study of leprosy cases, living in Parnaíba, State of Piauí, reported to the National System of Notifiable Diseases (SINAN), from 2007 to 2016. There were 582 cases of leprosy with hyperendemic detection in the general population in 2008, 2009 and 2016; and under < 15 years of age in 2008, 2014 and 2016, with a predominance of females (53.1%), brown (62.2%), aged 20-64 years (74.7%), complete and incomplete elementary school (56.4%), housewives (20.7%), living in the urban area (87.1%), reported by primary care (69.2%). The most frequent clinical and therapeutic findings were: multibacillary operational classification (53.8%); clinical forms: undetermined (30.6%) and virchowian (24.3%); single lesion (34.8%); no affected nerves (86.7%); degree of disability zero (70.6%); bacilloscopy not performed (26.7%); therapeutic regimen 12 doses (53.7%) and no reaction (70.8%). Regarding the mode of input, predominated new case (88.8%); mode of output, cure (87.9%) and detection mode: spontaneous demand (45.8%). Out of 2,106 registered contacts, 60.6% were examined. Leprosy is endemic to Parnaíba, State of Piauí. It is noteworthy that the hyperendemic detection rates occurred during years when there was intensification of active search for contacts and cases in the population.","PeriodicalId":7185,"journal":{"name":"Acta Scientiarum. Health Science","volume":"197 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76952365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The correlation between children’s own health control and their health perceptions and behaviours, and the associated factors 儿童自身健康控制与健康观念和行为的相关性及其相关因素

Acta Scientiarum. Health Science Pub Date : 2021-02-11 DOI: 10.4025/ACTASCIHEALTHSCI.V43I1.52849

Yildirim Hilal, Isik Kevser, Gulcek Emral

引用次数: 0

Prevalence of alcohol consumption and factors associated with binge drinking behavior among adolescents in the state of Pernambuco, Brazil, 2016 2016年巴西伯南布哥州青少年酒精消费流行率及与酗酒行为相关的因素

Acta Scientiarum. Health Science Pub Date : 2021-02-11 DOI: 10.4025/ACTASCIHEALTHSCI.V43I1.52633

Claudio Monteiro Freitas, J. Bezerra, F. Soares, Mallu Dias Soares, R. Lima, Fabiana de Godoy Bene Bezerra, M. Barros

{"title":"Prevalence of alcohol consumption and factors associated with binge drinking behavior among adolescents in the state of Pernambuco, Brazil, 2016","authors":"Claudio Monteiro Freitas, J. Bezerra, F. Soares, Mallu Dias Soares, R. Lima, Fabiana de Godoy Bene Bezerra, M. Barros","doi":"10.4025/ACTASCIHEALTHSCI.V43I1.52633","DOIUrl":"https://doi.org/10.4025/ACTASCIHEALTHSCI.V43I1.52633","url":null,"abstract":"To investigate the prevalence of alcohol consumption and the factors associated with binge drinking behavior among adolescents in the state of Pernambuco, Brazil. A cross-sectional study with a probabilistic sample of 6,002 adolescents composed of students from public high schools in Pernambuco, Brazil, aged 14 to 19 years. Binge drinking behavior was used as a dependent variable. The following were evaluated as possible risk factors: sociodemographic variables (gender, maternal education, marital status, work, religion); indicators of psychosocial stress (feelings of sadness; suicidal thoughts; feelings of loneliness; friends) and health risk behaviors (physical inactivity; number of sexual partners; drug use; and involvement in fights in the last year). Logistic regression was used to estimate odds ratios (OR). A total of 6,002 adolescents participated, with 75% reporting having consumed alcoholic beverages at least once in their lives. The prevalence of binge drinking in the last month was 17%. Adolescents without a religion had 81% (95%CI: 1.51; 2.16) more chance of consuming alcohol in excess. Adolescents who felt sad were 29% more likely to binge drink (95%CI: 1.08; 1.54), and adolescents who had already thought about suicide had 41% (95%CI: 1.13; 1.76) more chance to drink excessively. Adolescents who used illicit drugs had 4.6 times the chance (95%CI: 3.51; 6.17) of excessive drinking. Adolescents who engaged in four or more fights during the year were twice as likely to binge drink as those who did not fight (95%CI: 1.36; 2.88). The prevalence of alcohol consumption and binge drinking behavior was high. Sociodemographic factors, psychosocial stress and health risk behaviors were associated with binge drinking.","PeriodicalId":7185,"journal":{"name":"Acta Scientiarum. Health Science","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87260057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Antioxidant activity and hypoglycemic effect assessment of the leaves from Syzygium cumini (L.) Skeels in Wistar rats 茴香叶的抗氧化活性及降糖作用评价Wistar大鼠的骨骼

Acta Scientiarum. Health Science Pub Date : 2021-02-11 DOI: 10.4025/ACTASCIHEALTHSCI.V43I1.52931

L. Moreira, J. L. Santos, Lúcio Marques Vieira Souza, A. C. Marçal, A. S. Dias, S. S. Araújo, B. Araújo, C. Estevam

{"title":"Antioxidant activity and hypoglycemic effect assessment of the leaves from Syzygium cumini (L.) Skeels in Wistar rats","authors":"L. Moreira, J. L. Santos, Lúcio Marques Vieira Souza, A. C. Marçal, A. S. Dias, S. S. Araújo, B. Araújo, C. Estevam","doi":"10.4025/ACTASCIHEALTHSCI.V43I1.52931","DOIUrl":"https://doi.org/10.4025/ACTASCIHEALTHSCI.V43I1.52931","url":null,"abstract":"Syzygium cumini (L.) Skeels was adapted to the climatic conditions and soil types in Brazil. Its fruits, leaves and inner bark are used in folk medicine due to their high antioxidant, anti-inflammatory, anticarcinogenic and antidiabetic activities mainly associated with the presence of phenolic compounds. It is estimated that at least 300 million people worldwide develop diabetes and approximately 11 million people are carriers of the disease in Brazil. The objective of this work was to evaluate the in vitro antioxidant activity, as well as the hypoglycemic action of hydroethanolic extract (HEE), the ethyl acetate (EAF) and hydromethanolic (HMF) fractions from leaves of S. cumini (L.) Skeels in rats. All assays were carried out in three replications. Data were expressed as mean  SD and significance was evaluated by ANOVA and Bonferroni test (p < 0.05). The results indicate a significant (p < 0.05) total phenol content (207 ± 2.3 GAE mg g) and antioxidant activity (EC50 = 9.05 ± 0.170 μg mL) for EAF. HEE and its fractions showed no significant (p > 0.05) action to modulate glucose by the OGTT assay in nondiabetic mice compared to control. Thus the use of the plant against diabetes in individuals is not proven.","PeriodicalId":7185,"journal":{"name":"Acta Scientiarum. Health Science","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89960041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Evaluation of anxiety-like behaviors following ethanol withdrawal in mice: effects of cannabidiol 对小鼠乙醇戒断后焦虑样行为的评价:大麻二酚的作用

Acta Scientiarum. Health Science Pub Date : 2020-07-29 DOI: 10.4025/actascihealthsci.v42i1.53001

Leticia Pin Coltri, V. T. Bonassoli, H. Milani, Rubia M W Oliveira

{"title":"Evaluation of anxiety-like behaviors following ethanol withdrawal in mice: effects of cannabidiol","authors":"Leticia Pin Coltri, V. T. Bonassoli, H. Milani, Rubia M W Oliveira","doi":"10.4025/actascihealthsci.v42i1.53001","DOIUrl":"https://doi.org/10.4025/actascihealthsci.v42i1.53001","url":null,"abstract":"The abrupt interruption of ethanol consumption increases anxiety-like behaviors in rodents and may reflect different aspects of ethanol dependence in humans. Measuring emotional behaviors resulting from ethanol withdrawal may aid in testing potential pharmacological agents for the treatment of ethanol dependence. In the present study, we used forced expositon to ethanol 20% during 10 days to mice, followed by abrupt withdrawal of the substance. The animals were evaluated 7, 24 and 35 h after ethanol withdrawal in three different behavioral paradigms, i.e., the open field (OF), light dark (LD) transition and elevated plus maze (EPM), tests usually used to measure anxiety-like behaviors. This was done with the aim of identifying the best interval as well as the most appropriate behavioral test to detect the effects of drugs that can relieve anxiety induced by ethanol withdrawal in mice. We also evaluated the effect of cannabidiol (CBD 10, 30 and 60 mg kg) in ethanol withdrawn mice because it has been shown to alliviate drug addicton and present anti-anxiety effects. Our results show significant behavioral changes at 24 h following ethanol withdrawal. Diazepam (4 mg kg), used as a positive control, counteracted the effects of ethanol withdrawal in OF, LD box and EPM. Cannabidiol attenuated anxiety-like behavior produced at 24 h after abstinence from ethanol exposure only in the EPM test.","PeriodicalId":7185,"journal":{"name":"Acta Scientiarum. Health Science","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85044205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of horse riding equipment in activity of trunk and lower limb muscles in equine-assisted therapy 骑马器材对马辅助治疗中躯干和下肢肌肉活动的影响

Acta Scientiarum. Health Science Pub Date : 2020-07-23 DOI: 10.4025/actascihealthsci.v42i1.52739

J. B. Lage, M. F. Ribeiro, V. Teixeira, R. Rosa, A. A. Ferreira, Ana Paula Espindula

{"title":"Effect of horse riding equipment in activity of trunk and lower limb muscles in equine-assisted therapy","authors":"J. B. Lage, M. F. Ribeiro, V. Teixeira, R. Rosa, A. A. Ferreira, Ana Paula Espindula","doi":"10.4025/actascihealthsci.v42i1.52739","DOIUrl":"https://doi.org/10.4025/actascihealthsci.v42i1.52739","url":null,"abstract":"Equine-assisted therapy uses the horse in rehabilitation and/or education of people, such as Down syndrome (SD), cerebral palsy (PC) and intellectual disability (DI). In context, the rehabilitation program and horse riding equipment should be used according to the specific characteristics of each individual, becoming an ally in the quest for excellence in equine-assisted therapy programs. The aim was to evaluate the effect of riding equipment used in equine-assisted therapy on the muscular activity of trunk and lower limb of individuals with SD, PC and DI. The study included 15 individuals equally assigned to each group: SD, PC and DI with a mean age of 16.2 (± 1.10), 16 (± 1.22) e 16 (±0) years, respectively. The analysis of muscle activity was performed through surface electromyography, using four variations of horse riding equipment: saddle with and without feet supported on the stirrups and blanket with and without feet supported on the stirrups. Sigma Stat 3.5 software was used for statistical analysis. The Shapiro Wilk’s test was used for normality of the data, the Bartlett test for homogeneity of the variances and the Kruskal-Wallis test for repeated measures with no normal distribution. Statistically significant differences were observed for p < 0.05. The SD group presented a greater muscular activity of trunk and lower limbs with blanket equipment without the feet supported in the stirrups (H = 15.078, p = 0.002), as in the DI group (H = 8.302, p = 0.040), while in PC group was the saddle with feet supported in the stirrups (H = 11.137, p = 0.011). The choice of riding equipment used in equine-assisted therapy interferes differently in the pattern of muscular activation of the trunk and the lower limbs, according to the pathological processes of the practitioners. It should be an important aspect to consider when planning a treatment.","PeriodicalId":7185,"journal":{"name":"Acta Scientiarum. Health Science","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84419325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Occurrence of Mycoplasma spp. and Ureaplasma spp. in genital specimens 生殖道标本支原体和脲原体的发生

Acta Scientiarum. Health Science Pub Date : 2020-07-23 DOI: 10.4025/actascihealthsci.v42i1.50926

Nathally Claudiane de Souza Santos, R. B. Scodro, Vanessa Tatiana de Andrade, V. Siqueira, K. R. Caleffi-Ferracioli, Rubia Andreia Falleiros Padua, D. Micheletti, R. F. Cardoso

{"title":"Occurrence of Mycoplasma spp. and Ureaplasma spp. in genital specimens","authors":"Nathally Claudiane de Souza Santos, R. B. Scodro, Vanessa Tatiana de Andrade, V. Siqueira, K. R. Caleffi-Ferracioli, Rubia Andreia Falleiros Padua, D. Micheletti, R. F. Cardoso","doi":"10.4025/actascihealthsci.v42i1.50926","DOIUrl":"https://doi.org/10.4025/actascihealthsci.v42i1.50926","url":null,"abstract":"Mycoplasma spp. and Ureaplasma spp. belong to humans’ genitourinary microbiota and sometimes are associated with infections of the genitourinary tract. The aim of this study was to evaluate the occurrence of Mycoplasma spp. and Ureaplasma spp. in genital specimens from patients of the 15 Regional de Saúde of Paraná State, Brazil, and to correlate the results with clinical and laboratory data. A retrospective cross-sectional study was conducted, based on the analysis of results of vaginal, endocervical, urine and urethral culture for mycoplasmas from patients attended in a reference laboratory, from January 2009 to December 2016. We evaluated 2,475 results of culture for mycoplasmas. A total of 50.8% patients were positive for mycoplasmas. Of these, 76.8% had positive culture exclusively for Ureaplasma spp. and 4.7% for Mycoplasma hominis. Both microorganisms were isolated in the microbiology culture of 18.5% of patients. Among the positive culture, 81.4% had significant concentrations. Bacterial vaginosis was the most common alteration observed in association with mycoplasmas. The high positivity of cultures for mycoplasmas, especially Ureaplasma spp. found in our study, highlight the presence of these microorganisms in many of the genital tract disorders that can be sexually transmitted and, consequently, should not be neglected.","PeriodicalId":7185,"journal":{"name":"Acta Scientiarum. Health Science","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77091880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Linear mixed model for weight analysis in mice infected by Trypanosoma cruzi 克氏锥虫感染小鼠体重分析的线性混合模型

Acta Scientiarum. Health Science Pub Date : 2020-07-20 DOI: 10.4025/actascihealthsci.v42i1.49916

Roney Peterson Pereira, T. A. Guedes, É. C. Ferreira, S. M. Araújo, Larissa Aparecida Ricardini, L. Ciupa

{"title":"Linear mixed model for weight analysis in mice infected by Trypanosoma cruzi","authors":"Roney Peterson Pereira, T. A. Guedes, É. C. Ferreira, S. M. Araújo, Larissa Aparecida Ricardini, L. Ciupa","doi":"10.4025/actascihealthsci.v42i1.49916","DOIUrl":"https://doi.org/10.4025/actascihealthsci.v42i1.49916","url":null,"abstract":"The use of linear mixed models for nested structure longitudinal data is called hierarchical linear modeling. This modeling takes into account the dependence of existing data within each level and between hierarchical levels. The process of modeling, estimating and analyzing diagnoses was illustrated through data on the weights of mice experimentally infected by Trypanosoma cruzi, divided into different treatment groups, with the purpose of verifying the evolution of their body weight as a result of using different types of biotherapeutics produced from Gallus gallus domesticus (chicken) serum to treat Trypanosoma cruzi. Through the model selection criteria AIC and BIC and the likelihood ratio test, a model was chosen to describe the data correctly. Model diagnoses were then performed by means of residual analysis for both levels and an analysis of influential observations to verify if any observations were signaled as influencing the fixed effects, the components of variance and the adjusted values. After the analysis, it was possible to notice that the observations that were signaled as influential had little impact on the Model chosen initially, so it was maintained, with no differences being evidenced between the treatments with the biotherapeutics tested; only the Time variable and the Random intercept were necessary to describe the weight of the mice.","PeriodicalId":7185,"journal":{"name":"Acta Scientiarum. Health Science","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80168951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0