Shikha Sharma, B. V. Sunil Kumar, Kuldip Gupta, Ashwani Kumar
{"title":"Mammaglobin-A as a Diagnostic Marker of Canine Mammary Tumors: Insights from Immunohistochemical Analysis","authors":"Shikha Sharma, B. V. Sunil Kumar, Kuldip Gupta, Ashwani Kumar","doi":"10.1007/s40009-024-01444-x","DOIUrl":"10.1007/s40009-024-01444-x","url":null,"abstract":"<div><p>Mammaglobin-A (MAM-A) is a glycoprotein predominantly linked to mammary tissue. It is a secretory protein, characterized by its composition of 93 amino acids and a molecular weight of around 10 kDa. The primary objective of this study is to evaluate the tissue expression of MAM-A in different histotypes of canine mammary tumors (CMT). The present study includes a total of 40 samples of CMT and 5 samples of apparently healthy canine mammary tissues, which were subjected to histological and immunohistochemical examinations. Hyperimmune serum was generated against recombinant MAM-A (rMAM-A) in rabbits to establish a standardized immunohistochemical protocol for evaluating the expression of MAM-A protein in different histotypes of CMT. The histological study demonstrated a wide array of tumor classifications, predominantly consisting of carcinoma, followed by carcinosarcoma and sarcoma. The immunohistochemical examination demonstrated a pronounced expression of MAM-A in the majority of CMT histotypes. The immunohistochemical expression of MAM-A in CMT indicates its potential as a valuable diagnostic biomarker.</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"48 1","pages":"79 - 82"},"PeriodicalIF":1.2,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pandia Rajan Jeyaraj, Siva Prakash Asokan, Aravind Chellachi Kathiresan, Edward Rajan Samuel Nadar
{"title":"Perspective of Generalizing Deep Boltzmann Machine for ECG Signal Classification","authors":"Pandia Rajan Jeyaraj, Siva Prakash Asokan, Aravind Chellachi Kathiresan, Edward Rajan Samuel Nadar","doi":"10.1007/s40009-024-01424-1","DOIUrl":"10.1007/s40009-024-01424-1","url":null,"abstract":"<div><p>Deep learning is a highly efficient technique for handling large volume big data and decision-making processes. The above objective is achieved by incorporating healthcare service provider knowledge as a rule to meticulously classify physiological signal like Electrocardiogram (ECG) signal from the extracted large amount of big data from the wearable sensor. In this study, we generalized a novel deep Boltzmann machine (DBM) to diagnose arrhythmia in real-time ECG signals. The performance of proposed DBM was evaluated by accuracy, specificity, sensitivity and mean field interference of training algorithms. From the obtained results, we claim that the proposed deep learning model has high performance in the classification of most of the arrhythmia ECG and has high accuracy of 96.8% and sensitivity of 98.83% in classification. Moreover, the significance of proposed DBM model performs consistently on various real-time ECG dataset.</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"48 1","pages":"39 - 43"},"PeriodicalIF":1.2,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigations on 3D Printed Novel Stifel Prosthesis as IoT-Based Solution","authors":"Rupinder Singh, Arvind Kumar","doi":"10.1007/s40009-024-01442-z","DOIUrl":"10.1007/s40009-024-01442-z","url":null,"abstract":"<div><p>In the past, studies have been reported on the novel stifel prosthesis (SP) to address the patella luxation (PL) issues for different ages/breeds of canine. However, less has been reported on 3D printed SP as an Internet of Things (IoT) solution for online health monitoring of caine post-PL surgery. This study reports the investigations on novel 3D-printed SP for online health monitoring post-PL surgery in line with the microstrip patch antenna (MPA) concept. The study suggests the proposed solution has an acceptable rate at which energy is absorbed by the human body when exposed to an electromagnetic field (specific absorption ratio (SAR) of 1.4 W/kg). Also, the resonance frequency (R<sub>f</sub>) (for efficiently receiving and radiating electromagnetic energy) was observed as 3.61 GHz with insertion loss (S<sub>11</sub>) -25.25 dB while normal functioning/ movement of the patella in the trochlear grove. The shift in R<sub>f</sub> was observed for the movement of a sliding component fabricated by 3D printing of poly-lectic acid (PLA) using fused filament fabrication (FFF) in the cage/ race of 17 − 4 precipitate hardened (PH) stainless steel (SS) fabricated by direct metal laser sintering (DMLS) to mimic medial/ lateral PL. The R<sub>f</sub> was observed as 3.82 GHz (S<sub>11</sub> -24.26dB) and 3.79 GHz (S<sub>11</sub> -12.88 dB) for medial and lateral PL, respectively.</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"48 1","pages":"59 - 63"},"PeriodicalIF":1.2,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Folioceros Amboinensis – a Rare Hornwort, Discovered in Eastern Himalayan Bryo-Geographical Territory, India","authors":"S. K. Singh, Darshan Shukla","doi":"10.1007/s40009-024-01440-1","DOIUrl":"10.1007/s40009-024-01440-1","url":null,"abstract":"<div><p>Anthocerotophyta is a distinct group among bryophytes. The members of this group show characteristic similarity with Algae in having a single chloroplast with pyrenoid bodies, as well as thallose gametophytes like liverworts. They are unique among bryophytes in having a horn-like sporophyte with unlimited growth. The majority of members can fix atmospheric nitrogen by having Nostoc colonies embedded in their gametophytes. They also provide microhabitat to other small insects which is beneficial to the ecosystem. In India, they are represented by 7 genera viz., <i>Anthoceros</i>,<i> Folioceros</i>,<i> Notothylas</i>,<i> Phaeoceros</i>,<i> Megaceros</i> and a recently discovered genus <i>Phymatoceros.</i> The members of genus <i>Folioceros</i> mostly distributed in the tropical and subtropical regions of East and South-East Asia. <i>Folioceros amboinensis</i> (Schiffn.) Piippo [Anthocerotaceae; Anthocerotophyta], a very little-known species, earlier reported from Andaman & Nicobar Islands and Kerala in India, is reported and described here as a new distributional record from Mizoram, Eastern Himalayan Bryo-geographical territory. A detailed description, colour photo plate and SEM of sporoderm are provided.</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"48 1","pages":"103 - 108"},"PeriodicalIF":1.2,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tecomella undulata (Sm.) Seem (Lamiales: Bignoniaceae), a New Host Plant for Phenacoccus solenopsis Tinsley (Hemiptera: Pseudococcidae)","authors":"Tanmaya Kumar Bhoi, Sunil Joshi, Vipula Vyas, Varun Saini","doi":"10.1007/s40009-024-01441-0","DOIUrl":"10.1007/s40009-024-01441-0","url":null,"abstract":"<p>The cotton mealybug, <i>Phenacoccus solenopsis</i> is one of the most destructive polyphagous pests and is distributed worldwide. It is continuously expanding its host plants and known to feed on several commercial tree species. Survey was conducted during rainy and post rainy season 2023 at research farm of ICFRE-AFRI, Jodhpur, Rajasthan, India. During the survey, cotton mealybug was reported for the first time to feed on rohida tree, <i>Tecomella undulata</i>. nursery seedlings. This mealybug species is recorded for the first time on <i>Tecomella undulata</i>.</p>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"48 1","pages":"109 - 114"},"PeriodicalIF":1.2,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High Entropy Alloy Ni-Fe-Ti-Hf-Nb Addition Effect on Microstructure, Mechanical and Wear Behaviour of A356 Composite Fabricated by FSP Technique","authors":"Shashi Prakash Dwivedi, Shubham Sharma, Vandana Arora Sethi","doi":"10.1007/s40009-024-01434-z","DOIUrl":"10.1007/s40009-024-01434-z","url":null,"abstract":"<div><p>High Entropy Alloys (HEAs) have garnered substantial interest recently due to their unique blend of properties stemming from the presence of multiple elements in equiatomic or near-equiatomic compositions. This study delved into the impact of Ni-Fe-Ti-Hf-Nb addition as a high entropy alloy on the microstructure, mechanical characteristics, and wear behavior of an A356 composite. Fabricated through Friction Stir Processing (FSP), the composite benefited from refined microstructure and enhanced properties. The incorporation of Ni-Fe-Ti-Hf-Nb HEA altered the microstructure of the A356 composite, fostering unique phase formation, grain refinement, and improved homogeneity. These changes potentially translated to enhanced mechanical properties, notably hardness and tensile strength. Moreover, the addition of Ni-Fe-Ti-Hf-Nb HEA bolstered the wear resistance of the A356 composite. Consequently, the composite exhibited improved suitability for applications under abrasive or erosive conditions, with a notable 22.12% enhancement in tensile strength compared to A356 alone and a surface hardness boosted from 62 HV to 88 HV.</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"48 1","pages":"55 - 58"},"PeriodicalIF":1.2,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anup Chandra, K. K. Hazra, Ashok Kumar Parihar, Sujayanand G.K., G. P. Dixit
{"title":"‘ImageJ’ Based Screening Method for Field Pea Germplasm against Pea Leaf Miner (Phytomyza horticola Goureau)","authors":"Anup Chandra, K. K. Hazra, Ashok Kumar Parihar, Sujayanand G.K., G. P. Dixit","doi":"10.1007/s40009-024-01428-x","DOIUrl":"10.1007/s40009-024-01428-x","url":null,"abstract":"<div><p>\u0000 Accurately estimating crop infestation caused by insect pests is crucial, especially when screening a large panel of genotypes for potential resistant sources. The infestation by the pea leaf miner (PLM) is characterized by distinctive linear mines, often assessed by counting the number of infested leaves or visually approximating the infested leaf area. However, conventional estimation methods frequently suffer from inaccuracies. To counter this limitation, digital images of infested leaves were processed using ‘ImageJ’ software to precisely map both the total and infested leaf areas. This methodology was employed to evaluate the susceptibility of twenty different field pea (<i>Pisum sativum</i> L.) genotypes to PLM. The analysis revealed that foliage damage was highest in DPFPD 62 (10.2%) and lowest in Pant P 72 (0.55%). Additionally, three out of the twenty genotypes were categorized as ‘highly resistant’. Results indicated a negative correlation of foliage damage by PLM with leaf thickness (<i>p</i> = 0.008) and SPAD chlorophyll meter readings (<i>p</i> = 0.068). While a significant positive correlation was observed between foliage damage and leaf size/area (<i>p</i> = 0.002). Consequently, the precise estimation of PLM infestation through image analysis could offer a promising approach to gain in-depth insights into characterizing infestation severity in relation to host plant traits.</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"48 1","pages":"7 - 11"},"PeriodicalIF":1.2,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On the Recycled Acrylonitrile Butadiene Styrene Composite Filaments with Tuneable Thermo-Mechanical Properties","authors":"Ranvijay Kumar, Rupinder Singh, Nishant Ranjan, Vinay Kumar","doi":"10.1007/s40009-024-01433-0","DOIUrl":"10.1007/s40009-024-01433-0","url":null,"abstract":"<div><p>In the past two decades, several studies have been reported on the 3D printing of acrylonitrile butadiene styrene (ABS) based functional prototypes (of amorphous nature) using the fused filament fabrication (FFF) process. It has been reported that the reinforcements (commercial metallic powders) result in the tuned crystalline behaviour of the ABS matrix, leading to compromised 3D printing capabilities. This study highlights the fabrication of secondary (2°) recycled ABS filament with reinforcement of burnt incense stick powder waste (ISPW) for acceptable thermo-mechanical properties and 3D printing capabilities. The reinforcement of ISPW (0.75% by wt.) in ABS was selected based on the rheological and mechanical properties. The X-ray diffraction (XRD) results show an improvement in crystallinity (from 28.5 to 34.9%) with a minor change in mechanical strength (from 29.8 MPa to 29.47 MPa) in the ABS-0.75%ISPW composite. The differential scanning calorimetry (DSC) analysis outlined that glass transition temperature (Tg) was improved (from 94.97 °C to 105.27 °C) for the prepared composite. The results were also validated through Fourier-transform infrared spectroscopy (FTIR) analysis.</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"48 1","pages":"51 - 54"},"PeriodicalIF":1.2,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Climate-Induced Pandemics in the Plastisphere","authors":"Sung Hee Joo","doi":"10.1007/s40009-024-01439-8","DOIUrl":"10.1007/s40009-024-01439-8","url":null,"abstract":"<div><p>With the increasing manufacture of plastics and its resultant plastic waste generation, disease outbreaks are likely to occur through the interactive effects of climatic hazards and (transformed) plastic-induced antibiotic resistance. However, no information is available regarding the climatic hazards linked to antibiotic-resistant pandemics in the plastisphere. This comment article offers a new forum for commenting on issues that have not been addressed. Several approaches with remedial and mitigation strategies are suggested in four primary areas (i.e., manufacture of plastics, education, risk assessment, research in public health and medicine).</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"48 1","pages":"135 - 137"},"PeriodicalIF":1.2,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhancing GaN LED Efficiency with Advanced Quantum Well Structure","authors":"Shahzaib Aftab, Shabbir Majeed Chaudhry","doi":"10.1007/s40009-024-01457-6","DOIUrl":"10.1007/s40009-024-01457-6","url":null,"abstract":"<div><p>This short communication presents a novel GaN LED design featuring multiple quantum wells (MQW). The MQW is designed using a specific arrangement of GaN/AlGaN layers in a 5-period superlattice (SL) configuration, positioned both above and below a 3-period stack of AlGaN/InGaN active layers (SAL). The incorporation of SL layers effectively curbs electron and hole leakage from the SAL towards the anode and cathode. This proposed structure optimizes radiative recombination within the quantum wells, resulting in remarkable LED performance: an impressive output power of 9.77 W/cm and internal quantum efficiency of 89%. Notably, efficiency droop is reduced to merely 3.33% at maximum current, rendering it highly promising for low-power lighting applications.</p></div>","PeriodicalId":717,"journal":{"name":"National Academy Science Letters","volume":"48 2","pages":"195 - 198"},"PeriodicalIF":1.2,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143856524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}