Acta physiologica Scandinavica最新文献_第4页

Prostaglandin-mediated inhibition of noradrenaline release: IV. Prostaglandin synthesis is stimulated by myocardial adrenoceptors differing from the alpha- and beta-type. 前列腺素介导的去甲肾上腺素释放抑制:IV.不同于α型和β型的心肌肾上腺素能刺激前列腺素合成。

Acta physiologica Scandinavica Pub Date : 1978-03-01

A Wennmalm, T Brundin

{"title":"Prostaglandin-mediated inhibition of noradrenaline release: IV. Prostaglandin synthesis is stimulated by myocardial adrenoceptors differing from the alpha- and beta-type.","authors":"A Wennmalm, T Brundin","doi":"","DOIUrl":"","url":null,"abstract":"The release of prostaglandin E elicited by sympathomimetic amines was studied in the isolated rabbit heart. The hearts were prepared according to Langendorff, with conventional recording of stroke frequency and contractile force. Assays were made of the outflow of PGE during exposition to equimolar concentrations of methoxamine, noradrenaline, adrenaline and isoprenaline, in the absence and in the presence of phentolamine or propranolol. Noradrenaline caused an almost four-fold increase in the basal outflow of PGE from the heart, while methoxamine (an alpha-adrenoceptor agonist) and isoprenaline (a beta-adrenoceptor agonist) were both ineffective in this respect. Thus, the PGE-releasing capacity of the drugs was not correlated to their ability to activate alpha- or or beta-adrenoceptors. Furthermore, no relation was obtained between the PGE release induced by the drugs and the increase in heart rate and contractile force elicited by them. It is suggested that sympathomimetic drugs trigger PGE synthesis and release in the rabbit myocardium following activation of a hitherto unobserved adrenoceptive mechanism, optimally stimulated by NA.","PeriodicalId":7160,"journal":{"name":"Acta physiologica Scandinavica","volume":"102 3","pages":"374-81"},"PeriodicalIF":0.0,"publicationDate":"1978-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11847165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamics of saliva secretion and tissue volume changes during parasympathetic stimulation in the constant flow perfused cat submandibular gland. 恒流灌注猫颌下腺副交感神经刺激时唾液分泌和组织体积变化的动态。

Acta physiologica Scandinavica Pub Date : 1978-03-01

J Lundvall, J Holmberg

引用次数: 0

The effect of CO2 on peripheral airways. 二氧化碳对周围气道的影响。

Acta physiologica Scandinavica Pub Date : 1976-10-01

T M Nielsen, O F Pedersen

引用次数: 0

Aggregation fo blood platelets and increased hydraulic conductivity of pulmonary exchange vessels. 血小板聚集和肺交换血管的水力传导能力增加。

Acta physiologica Scandinavica Pub Date : 1976-10-01

J Vaage, G Nicolaysen, B A Waaler

{"title":"Aggregation fo blood platelets and increased hydraulic conductivity of pulmonary exchange vessels.","authors":"J Vaage, G Nicolaysen, B A Waaler","doi":"","DOIUrl":"","url":null,"abstract":"Pulmonary microembolization secondary to platelet aggregation has been suggested to be a pathogenetic component of the shock lung syndrome. In vitro experiments have also shown that platelets can release factors with a permeability-enhancing activity. We studied the effect of collagen-induced platelet aggregation on the hydraulic conductivity of thexchange vessels in isolated, blood-perfused rabbit lungs. The net rate of fluid filtration in each pair of lungs was determined during standardized elevations of left atrial pressure before and after platelet aggregation induced by intraarterial collagen infusions. Such infusions were followed by a significant, but transient increase in the net rate of fluid filtration. These lungs were papaverinized so that collagen infusions caused only minor increases in inflow pressure. Separate experiments indicated that the observed increase in pulmonary arterial pressure could not explain the increase in net filtration rate after collagen infusion. When platelet-poor plasma was used as a perfusate no change in the net rate of fluid filtration was observed after collagen infusion. The conclusion from these experiments is then that intravascular platelet aggregation induced by collagen infusion caused a transient increase in the permeability of the pulmonary exchange vessels.","PeriodicalId":7160,"journal":{"name":"Acta physiologica Scandinavica","volume":"98 2","pages":"175-84"},"PeriodicalIF":0.0,"publicationDate":"1976-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12165512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Choline acetyltransferase activity and weight of salivary glands in rats at different ages. 不同年龄大鼠唾液腺胆碱乙酰转移酶活性与体重的关系。

Acta physiologica Scandinavica Pub Date : 1976-10-01

J Ekström

引用次数: 0

A comparative study of in vitro metabolism of histamine in various tissues from domestic animals (cow, sheep, horse and pig). 组胺在家畜(牛、羊、马、猪)不同组织中体外代谢的比较研究。

Acta physiologica Scandinavica Pub Date : 1973-07-01

K A Eliassen

引用次数: 0

Comparison of the effect of different types of exercise on the baroreflex regulation of heart rate. 不同类型运动对心率压力反射调节效果的比较。

Acta physiologica Scandinavica Pub Date : 1972-12-01

D J Cunningham, E S Petersen, R Peto, T G Pickering, P Sleight