{"title":"High energy density storage, antifungal activity and enhanced bioimaging by green self-doped heteroatom carbon dots","authors":"Mohd Abdullah Sheikh, R. S. Chandok, Khan Abida","doi":"10.1186/s11671-023-03910-9","DOIUrl":"10.1186/s11671-023-03910-9","url":null,"abstract":"<div><p>Self-heteroatom-doped N-carbon dots (N-CDs) with a 2.35 eV energy gap and a 65.5% fluorescence quantum yield were created using a one-step, efficient, inexpensive, and environmentally friendly microwave irradiation method. FE-SEM, EDX, FT-IR, XRD, UV–VIS spectroscopy, FL spectroscopy, and CV electrochemical analysis were used to characterise the produced heteroatom-doped N-CDs. The graphitic carbon dot surface is doped with heteroatom functional groups such (S, P, K, Mg, Zn) = 1%, in addition to the additional passivating agent (N), according to the EDX surface morphology and the spontaneous heteroatom doping was caused by the heterogeneous chemical composition of pumpkin seeds. These spontaneous heteroatom-doped N-CDs possess quasispherical amorphous graphitic structure with an average size of less than 10 nm and the interplaner distance of 0.334 nm. Calculations utilising cyclic voltammetry showed that the heteroatom-doped N-CDs placed on nickel electrodes had a high specific capacitance value of 1044 F/g at a scan rate of 10 mV/s in 3 M of KOH electrolyte solution. Furthermore, it demonstrated a high energy and power density of 28.50 Wh/kg and 3350 W/kg, respectively. The higher value of specific capacitance and energy density were attributed to the fact that the Ni/CDs electrode material possesses both EDLC and PC properties due to the sufficient surface area and the multiple active sites of the prepared N-CDs. Furthermore, the heteroatom N-CDs revealed the antifungal action and bioimaging of the \"Cladosporium cladosporioides\" mould, which is mostly accountable for economic losses in agricultural products. The functional groups of nitrogen, sulphur, phosphorus, and zinc on the surface of the CDs have strong antibacterial and antifungal properties as well as fluorescence enhanced bioimaging.</p></div>","PeriodicalId":715,"journal":{"name":"Nanoscale Research Letters","volume":"18 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49694810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tuning nanofiltration membrane performance: OH–MoS2 nanosheet engineering and divalent cation influence on fouling and organic removal","authors":"Deepak Surendhra Mallya, Guoliang Yang, Weiwei Lei, Shobha Muthukumaran, Kanagaratnam Baskaran","doi":"10.1186/s11671-023-03909-2","DOIUrl":"10.1186/s11671-023-03909-2","url":null,"abstract":"<div><p>Natural organic matter (NOM) present in surface water causes severe organic fouling of nanofiltration (NF) membranes employed for the production of potable water. Calcium (Ca<sup>2+</sup>) and magnesium (Mg<sup>2+</sup>) are alkaline earth metals present in natural surface water and severely exacerbate organic fouling owing to their ability to cause charge neutralization, complexation, and bridging of NOM and the membrane surface. Hence, it is of practical significance to engineer membranes with properties suitable for addressing organic fouling in the presence of these cations. This study employed OH-functionalized molybdenum disulphide (OH–MoS<sub>2</sub>) nanosheets as nanofillers via the interfacial polymerization reaction to engineer NF membranes for enhanced removal of NOM and fouling mitigation performance. At an optimized concentration of 0.010 wt.% of OH–MoS<sub>2</sub> nanosheet, the membrane was endowed with higher hydrophilicity, negative charge and rougher membrane morphology which enhanced the pure water permeance by 46.33% from 11.2 to 16.39 L m<sup>−2</sup> h<sup>−1</sup> bar<sup>−1</sup> while bridging the trade-off between permeance and salt selectivity. The fouling performance was evaluated using humic acid (HA) and sodium alginate (SA), which represent the hydrophobic and hydrophilic components of NOM in the presence of 0, 0.5, and 1 mM Ca<sup>2+</sup> and Mg<sup>2+</sup>, respectively, and the performance was benchmarked with control and commercial membranes. The modified membrane exhibited normalized fluxes of 95.09% and 93.26% for HA and SA, respectively, at the end of the 6 h filtration experiments, compared to the control membrane at 89.71% and 74.25%, respectively. This study also revealed that Ca<sup>2+</sup> has a more detrimental effect than Mg<sup>2+</sup> on organic fouling and NOM removal. The engineered membrane outperformed the commercial and the pristine membranes during fouling tests in the presence of 1 mM Ca<sup>2+</sup> and Mg<sup>2+</sup> in the feed solution. In summary, this study has shown that incorporating OH–MoS<sub>2</sub> nanosheets into membranes is a promising strategy for producing potable water from alternative water sources with high salt and NOM contents.</p></div>","PeriodicalId":715,"journal":{"name":"Nanoscale Research Letters","volume":"18 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49694811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicolás Santos, Santiago Valenzuela, Camilo Segura, Igor Osorio-Roman, Macarena S. Arrázola, Concepción Panadero-Medianero, Paula A. Santana, Manuel Ahumada
{"title":"Poly(ethylene imine)-chitosan carbon dots: study of its physical–chemical properties and biological in vitro performance","authors":"Nicolás Santos, Santiago Valenzuela, Camilo Segura, Igor Osorio-Roman, Macarena S. Arrázola, Concepción Panadero-Medianero, Paula A. Santana, Manuel Ahumada","doi":"10.1186/s11671-023-03907-4","DOIUrl":"10.1186/s11671-023-03907-4","url":null,"abstract":"<div><p>Carbon dots (CDs) have been quickly extended for nanomedicine uses because of their multiple applications, such as bioimaging, sensors, and drug delivery. However, the interest in increasing their photoluminescence properties is not always accompanied by cytocompatibility. Thus, a knowledge gap exists regarding their interactions with biological systems linked to the selected formulations and synthesis methods. In this work, we have developed carbon dots (CDs) based on poly (ethylene imine) (PEI) and chitosan (CS) by using microwave irradiation, hydrothermal synthesis, and a combination of both, and further characterized them by physicochemical and biological means. Our results indicate that synthesized CDs have sizes between 1 and 5 nm, a high presence of amine groups on the surface, and increased positive ζ potential values. Further, it is established that the choice and use of different synthesis procedures can contribute to a different answer to the CDs regarding their optical and biological properties. In this regard, PEI-only CDs showed the longest photoluminescent emission lifetime, non-hemolytic activity, and high toxicity against fibroblast. On the other hand, CS-only CDs have higher PL emission, non-cytotoxicity associated with fibroblast, and high hemolytic activity. Interestingly, their combination using the proposed methodologies allow a synergic effect in their CDs properties. Therefore, this work contributes to developing and characterizing CD formulations based on PEI and CS and better understanding the CD’s properties and biological interaction.</p></div>","PeriodicalId":715,"journal":{"name":"Nanoscale Research Letters","volume":"18 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Carrier lifetime modulation on current capability of SiC PiN diodes in a pulsed system","authors":"Xingliang Xu, Lin Zhang, lianghui Li, Zhiqiang Li, Juntao Li, Jian Zhang, Peng Dong","doi":"10.1186/s11671-023-03905-6","DOIUrl":"10.1186/s11671-023-03905-6","url":null,"abstract":"<div><p>Silicon carbide (SiC) PiN diode has shown substantial promise as the freewheel diode for switch protection in a pulsed system. In this paper, we investigate the carrier lifetime (<i>τ</i>) modulation on pulsed current capability of SiC PiN diodes. The carrier lifetime in 4H–SiC is modulated by the generation of the <i>Z</i><sub>1/2</sub> center through neutron irradiation. Surprisingly, we found that the pulsed current of SiC PiN diodes shows a limited improvement when the carrier lifetime (<i>τ</i>) increases from 0.22 to 1.3 μs, while is significantly promoted as the carrier lifetime increases from 0.03 to 0.22 μs. This changing trend is obviously different from the on-state resistance, which decreases with the increased carrier lifetime. The simulation result indicates that the heat generation (i.e., maximum temperature rise) inside the PiN diodes, especially in the drift layer, is remarkably aggravated in the pulse tests for <i>τ</i> < 0.1 μs, but which is significantly suppressed as carrier lifetime rises to 0.2 μs and above. Therefore, the dependence of pulsed current on carrier lifetime is ascribed to the heat generation resulting from the carrier lifetime controlled conductivity modulation effect, which hence affects the temperature rise and brings about the failure of SiC PiN diodes under high pulsed current.</p></div>","PeriodicalId":715,"journal":{"name":"Nanoscale Research Letters","volume":"18 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579193/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Protein-modified nanomaterials: emerging trends in skin wound healing","authors":"Deepinder Sharda, Pawandeep Kaur, Diptiman Choudhury","doi":"10.1186/s11671-023-03903-8","DOIUrl":"10.1186/s11671-023-03903-8","url":null,"abstract":"<div><p>Prolonged inflammation can impede wound healing, which is regulated by several proteins and cytokines, including IL-4, IL-10, IL-13, and TGF-β. Concentration-dependent effects of these molecules at the target site have been investigated by researchers to develop them as wound-healing agents by regulating signaling strength. Nanotechnology has provided a promising approach to achieve tissue-targeted delivery and increased effective concentration by developing protein-functionalized nanoparticles with growth factors (EGF, IGF, FGF, PDGF, TGF-β, TNF-α, and VEGF), antidiabetic wound-healing agents (insulin), and extracellular proteins (keratin, heparin, and silk fibroin). These molecules play critical roles in promoting cell proliferation, migration, ECM production, angiogenesis, and inflammation regulation. Therefore, protein-functionalized nanoparticles have emerged as a potential strategy for improving wound healing in delayed or impaired healing cases. This review summarizes the preparation and applications of these nanoparticles for normal or diabetic wound healing and highlights their potential to enhance wound healing.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":715,"journal":{"name":"Nanoscale Research Letters","volume":"18 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus","authors":"Caifeng Ren, Qiyun Ke, Xiaoxia Fan, Keke Ning, Yuan Wu, Jiangong Liang","doi":"10.1186/s11671-023-03900-x","DOIUrl":"10.1186/s11671-023-03900-x","url":null,"abstract":"<div><p>Traditional Chinese medicines (TCMs)/nanopreparations as viral antagonists exhibited a structure–function correlation, i.e., the differences in surface area/volume ratio caused by the variations in shape and size could result in different biochemical properties and biological activities, suggesting an important impact of morphology and structure on the antiviral activity of TCM-based nanoparticles. However, few studies paid attention to this aspect. Here, the effect of TCM-based nanoparticles with different morphologies on their antiviral activity was explored by synthesizing rhein/silver nanocomposites (Rhe@AgNPs) with spherical (S-Rhe/Ag) and linear (L-Rhe/Ag) morphologies, using rhein (an active TCM ingredient) as a reducing agent and taking its self-assembly advantage. Using porcine reproductive and respiratory syndrome virus (PRRSV) as a model virus, the inhibitory effects of S-Rhe/Ag and L-Rhe/Ag on PRRSV were compared. Results showed that the product morphology could be regulated by varying pH values, and both S- and L-Rhe/Ag exhibited good dispersion and stability, but with a smaller size for L-Rhe/Ag. Antiviral experiments revealed that Rhe@AgNPs could effectively inhibit PRRSV infection, but the antiviral effect was morphology-dependent. Compared with L-Rhe/Ag, S-Rhe/Ag could more effectively inactivate PRRSV in vitro and antagonize its adsorption, invasion, replication, and release stages. Mechanistic studies indicated that Rhe@AgNPs could reduce the production of reactive oxygen species (ROS) induced by PRRSV infection, and S-Rhe/Ag also had stronger ROS inhibitory effect. This work confirmed the inhibitory effect of Rhe@AgNPs with different morphologies on PRRSV and provided useful information for treating PRRSV infection with metal nanoparticles synthesized from TCM ingredients.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":715,"journal":{"name":"Nanoscale Research Letters","volume":"18 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41221945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joseph Ekhebume Ogbezode, Ucheckukwu Stella Ezealigo, Abdulhakeem Bello, Vitalis Chioh Anye, Azikiwe Peter Onwualu
{"title":"A narrative review of the synthesis, characterization, and applications of iron oxide nanoparticles","authors":"Joseph Ekhebume Ogbezode, Ucheckukwu Stella Ezealigo, Abdulhakeem Bello, Vitalis Chioh Anye, Azikiwe Peter Onwualu","doi":"10.1186/s11671-023-03898-2","DOIUrl":"10.1186/s11671-023-03898-2","url":null,"abstract":"<div><p>The significance of green synthesized nanomaterials with a uniform shape, reduced sizes, superior mechanical capabilities, phase microstructure, magnetic behavior, and superior performance cannot be overemphasized. Iron oxide nanoparticles (IONPs) are found within the size range of 1–100 nm in nanomaterials and have a diverse range of applications in fields such as biomedicine, wastewater purification, and environmental remediation. Nevertheless, the understanding of their fundamental material composition, chemical reactions, toxicological properties, and research methodologies is constrained and extensively elucidated during their practical implementation. The importance of producing IONPs using advanced nanofabrication techniques that exhibit strong potential for disease therapy, microbial pathogen control, and elimination of cancer cells is underscored by the adoption of the green synthesis approach. These IONPs can serve as viable alternatives for soil remediation and the elimination of environmental contaminants. Therefore, this paper presents a comprehensive analysis of the research conducted on different types of IONPs and IONP composite-based materials. It examines the synthesis methods and characterization techniques employed in these studies and also addresses the obstacles encountered in prior investigations with comparable objectives. A green engineering strategy was proposed for the synthesis, characterization, and application of IONPs and their composites with reduced environmental impact. Additionally, the influence of their phase structure, magnetic properties, biocompatibility, toxicity, milling time, nanoparticle size, and shape was also discussed. The study proposes the use of biological and physicochemical methods as a more viable alternative nanofabrication strategy that can mitigate the limitations imposed by the conventional methods of IONP synthesis.</p></div>","PeriodicalId":715,"journal":{"name":"Nanoscale Research Letters","volume":"18 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41184314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tejaswini S. Rao, Indrajit Mondal, Bharath Bannur, Giridhar U. Kulkarni
{"title":"A scalable solution recipe for a Ag-based neuromorphic device","authors":"Tejaswini S. Rao, Indrajit Mondal, Bharath Bannur, Giridhar U. Kulkarni","doi":"10.1186/s11671-023-03906-5","DOIUrl":"10.1186/s11671-023-03906-5","url":null,"abstract":"<div><p>Integration and scalability have posed significant problems in the advancement of brain-inspired intelligent systems. Here, we report a self-formed Ag device fabricated through a chemical dewetting process using an Ag organic precursor, which offers easy processing, scalability, and flexibility to address the above issues to a certain extent. The conditions of spin coating, precursor dilution, and use of solvents were varied to obtain different dewetted structures (broadly classified as bimodal and nearly unimodal). A microscopic study is performed to obtain insight into the dewetting mechanism. The electrical behavior of selected bimodal and nearly unimodal devices is related to the statistical analysis of their microscopic structures. A capacitance model is proposed to relate the threshold voltage (V<sub>th</sub>) obtained electrically to the various microscopic parameters. Synaptic functionalities such as short-term potentiation (STP) and long-term potentiation (LTP) were emulated in a representative nearly unimodal and bimodal device, with the bimodal device showing a better performance. One of the cognitive behaviors, associative learning, was emulated in a bimodal device. Scalability is demonstrated by fabricating more than 1000 devices, with 96% exhibiting switching behavior. A flexible device is also fabricated, demonstrating synaptic functionalities (STP and LTP).</p></div>","PeriodicalId":715,"journal":{"name":"Nanoscale Research Letters","volume":"18 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41160579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Toral-Lopez, E. G. Marin, F. Pasadas, M. D. Ganeriwala, F. G. Ruiz, D. Jiménez, A. Godoy
{"title":"Reconfigurable frequency multipliers based on graphene field-effect transistors","authors":"A. Toral-Lopez, E. G. Marin, F. Pasadas, M. D. Ganeriwala, F. G. Ruiz, D. Jiménez, A. Godoy","doi":"10.1186/s11671-023-03884-8","DOIUrl":"10.1186/s11671-023-03884-8","url":null,"abstract":"<div><p>Run-time device-level reconfigurability has the potential to boost the performance and functionality of numerous circuits beyond the limits imposed by the integration density. The key ingredient for the implementation of reconfigurable electronics lies in ambipolarity, which is easily accessible in a substantial number of two-dimensional materials, either by contact engineering or architecture device-level design. In this work, we showcase graphene as an optimal solution to implement high-frequency reconfigurable electronics. We propose and analyze a split-gate graphene field-effect transistor, demonstrating its capability to perform as a dynamically tunable frequency multiplier. The study is based on a physically based numerical simulator validated and tested against experiments. The proposed architecture is evaluated in terms of its performance as a tunable frequency multiplier, able to switch between doubler, tripler or quadrupler operation modes. Different material and device parameters are analyzed, and their impact is assessed in terms of the reconfigurable graphene frequency multiplier performance.</p></div>","PeriodicalId":715,"journal":{"name":"Nanoscale Research Letters","volume":"18 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41143600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}