Acta Stomatologica Croatica最新文献

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Exploring the Root Canal Morphology of Third Molars in the Bosnia and Herzegovina Population. 探索波斯尼亚和黑塞哥维那人口中第三磨牙的根管形态。
IF 1.4
Acta Stomatologica Croatica Pub Date : 2024-09-01 DOI: 10.15644/asc58/3/6
Aida Džanković, Amra Mahmutovic, Samra Korač, Irmina Tahmiščija, Alma Konjhodžić, Lajla Hasić-Branković, Naida Hadžiabdić
{"title":"Exploring the Root Canal Morphology of Third Molars in the Bosnia and Herzegovina Population.","authors":"Aida Džanković, Amra Mahmutovic, Samra Korač, Irmina Tahmiščija, Alma Konjhodžić, Lajla Hasić-Branković, Naida Hadžiabdić","doi":"10.15644/asc58/3/6","DOIUrl":"10.15644/asc58/3/6","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to evaluate the root canal morphology of third molars in the Bosnia-Herzegovina population.</p><p><strong>Materials and methods: </strong>A total of 241 extracted third molars (105 maxillary and 136 mandibular) were subjected to a clearing procedure. The specimens were categorized into ten groups based on the Alavi classification for maxillary third molars (MaxTMs), and six groups were based on the Gulabivala classification for mandibular third molars (ManTMs). Root canal type according to the Vertucci classification, the presence and position of lateral canals, and intercanal communication were analyzed using a stereomicroscope x15.</p><p><strong>Results: </strong>MaxTMs had three roots in 77.13% of the samples. Among MaxTMs, the most common morphology was three fused roots (33.33%) and Vertucci's type VIII (54. 28% of samples in Alavi's Group IV). 60.29% of ManTMs have two separate roots (Gulabivala's Groups II and III). The most prevalent types in mesial roots were type I (41.46% in Group II) and type IV (48.78% in Group III), although type I predominated in distal roots (91.24% and 100% in Groups II and III, respectively).</p><p><strong>Conclusion: </strong>Single-rooted third molars usually have a root canal morphology that is more favorable for endodontic treatment. In contrast, third molars with fused roots often have more complex root canal morphology.</p>","PeriodicalId":7154,"journal":{"name":"Acta Stomatologica Croatica","volume":"58 3","pages":"255-266"},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Steroidal Anti-Inflammatory Drugs for Oral Surgery: A Systematic Review and Meta-Analysis. 用于口腔手术的类固醇消炎药:系统回顾与元分析》。
IF 1.4
Acta Stomatologica Croatica Pub Date : 2024-09-01 DOI: 10.15644/asc58/3/7
Cristiana Palmela Pereira, Madalena Mourão Tropa, Rui Santos, Ana Rodrigues, Maria Fátima Brilhante, Francisco Azevedo Coutinho, Adriana Resende, Diana Augusto, Francisco Salvado E Silva
{"title":"Steroidal Anti-Inflammatory Drugs for Oral Surgery: A Systematic Review and Meta-Analysis.","authors":"Cristiana Palmela Pereira, Madalena Mourão Tropa, Rui Santos, Ana Rodrigues, Maria Fátima Brilhante, Francisco Azevedo Coutinho, Adriana Resende, Diana Augusto, Francisco Salvado E Silva","doi":"10.15644/asc58/3/7","DOIUrl":"10.15644/asc58/3/7","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the present study was to investigate if there are differences in mitigation acute pain following oral surgery procedures within a hospital setting and regarding various medication regimens.</p><p><strong>Materials and methods: </strong>A systematic literature search was performed between the years 2013 and 2023, including the databases PUBMED, Cochrane and Scopus, to identify the clinical trials investigating the prescription of non-steroidal (NSAID's) anti-inflammatory drugs before or after an oral surgery. A meta-analysis with meta-regression model was employed on the primary and secondary outcomes, such as pain, swelling and trismus.</p><p><strong>Results: </strong>Thirty-six articles were included, 6 of them being retrospective and 30 prospective, with a higher proportion of women than men, at a ratio of 1.34:1 and an average age of 31.9 years. Drugs with medium duration of action demonstrated lower values for pain and swelling. Regarding these parameters, pain and swelling, propionic acid derivatives and acetic acid derivatives exhibited lower values respectively.</p><p><strong>Conclusions: </strong>The quality of evidence was low to very low- certainty. The meta-analysis suggests that postoperative pain, swelling and trismus following oral surgery management may be effectively treated with the following drugs: NSAID medium-duration action drugs; propionic acid derivatives for lower pain levels and acetic acid derivatives for lower swelling measures; and Ibuprofen 400mg every 8h for 3 days or less.</p><p><strong>Clinical relevance: </strong>Anti-inflammatory and analgesic drugs are prescribed to prevent or treat dental pain. Ibuprofen 400mg was the most prescribed drug after or before an oral surgery procedure. However, the evidence is indirect and needs to be interpreted with caution.</p>","PeriodicalId":7154,"journal":{"name":"Acta Stomatologica Croatica","volume":"58 3","pages":"267-290"},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibacterial Efficacy of Rotary and Reciprocating Instrumentation Techniques. 旋转式和往复式器械技术的抗菌功效
IF 1.4
Acta Stomatologica Croatica Pub Date : 2024-09-01 DOI: 10.15644/asc58/3/5
Anja Sesar, Ana Budimir, Ivica Anić, Gabrijela Kapetanović Petričević, Ivona Bago
{"title":"Antibacterial Efficacy of Rotary and Reciprocating Instrumentation Techniques.","authors":"Anja Sesar, Ana Budimir, Ivica Anić, Gabrijela Kapetanović Petričević, Ivona Bago","doi":"10.15644/asc58/3/5","DOIUrl":"10.15644/asc58/3/5","url":null,"abstract":"<p><strong>Objectives: </strong>To clinically evaluate the effectiveness of rotary (ProTaper Next [PTN]) and reciprocating (Wave One Gold [WOG]) instrumentation techniques in eliminating bacteria from the root canals of teeth with apical periodontitis during a single-visit root canal treatment.</p><p><strong>Materials and methods: </strong>Forty patients were randomly assigned to the WOG or PTN instrumentation techniques groups. A single-visit root canal treatment was performed on all the patients. In both groups, root canals were irrigated with 10 ml of sodium hypochlorite (NaOCl) and the final irrigation protocol was applied. Microbiological samples from the root canal were collected initially (Sample 1), after chemo-mechanical instrumentation (Sample 2), and after the final irrigation protocol (Sample 3). Quantification of bacteria at each stage of root canal treatment was performed using the culture method (colony-forming units [CFUs]), and bacterial species were identified using MALDI-TOF mass spectrometry.</p><p><strong>Results: </strong>There were 55 aerobic and anaerobic bacterial species identified. Chemo-mechanical root canal treatment with both instrumentation techniques and the final irrigation protocol significantly reduced the number of CFUs (p<0.001). There were no statistically significant differences in antibacterial efficacy between WOG and PTN groups (p>0.05).</p><p><strong>Conclusion: </strong>Although both root canal instrumentation techniques were highly effective in removing bacteria from the necrotic canals of teeth with chronic apical periodontitis, no complete eradication of bacteria was found in any sample.</p>","PeriodicalId":7154,"journal":{"name":"Acta Stomatologica Croatica","volume":"58 3","pages":"245-254"},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Survival of Reduced-Thickness Monolithic Lithium-Disilicate Crowns: A 3-Year Randomized Controlled Trial. 厚度减小的整体式二硅酸锂冠的临床存活率:为期 3 年的随机对照试验。
IF 1.4
Acta Stomatologica Croatica Pub Date : 2024-06-01 DOI: 10.15644/asc58/2/2
Davor Špehar, Marko Jakovac
{"title":"Clinical Survival of Reduced-Thickness Monolithic Lithium-Disilicate Crowns: A 3-Year Randomized Controlled Trial.","authors":"Davor Špehar, Marko Jakovac","doi":"10.15644/asc58/2/2","DOIUrl":"10.15644/asc58/2/2","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this randomized controlled trial was to see if the minimally invasive approach (reduced restoration thickness) would result in good clinical success of monolithic ceramic crowns compared to conventional layered all-ceramic crowns, and thus be an alternative to conventional tooth preparation.</p><p><strong>Materials and methods: </strong>The ceramic that was investigated was IPS e.max lithium-disilicate ceramic produced using two different processing methods. A comparison was made between monolithic crowns with reduced thickness and standard layered crowns. Fifty-two patients, who had undergone endodontic treatment on either a premolar or molar, were randomly assigned into two groups. The teeth intended for layered crowns underwent to a 2 mm occlusal reduction with a 1 mm rounded shoulder, whereas the teeth intended for monolithic crowns underwent to a 1 mm reduction in the occlusal area with a 0.6 mm rounded shoulder. The clinical success was evaluated in eight categories using modified United States Public Health Service (USPHS) criteria. The observation period was 36 months, with control appointments every 6 months.</p><p><strong>Results: </strong>There was no significant difference in clinical success between monolithic and conventional layered crowns after 3 years. One monolithic crown fractured while all other crowns were intact and the survival rate was 96%. All layered crowns were intact and the survival rate was 100%.</p><p><strong>Conclusion: </strong>The results of this study indicate that the minimally invasive approach can be a good alternative to conventional tooth preparation. IPS e.max lithium-disilicate ceramic demonstrated an exceptional three-year survival rate independently of the thickness of the material.</p>","PeriodicalId":7154,"journal":{"name":"Acta Stomatologica Croatica","volume":"58 2","pages":"123-135"},"PeriodicalIF":1.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11256870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Periodontal Disease in Patients with Ischemic Stroke - an Exploratory Study. 缺血性中风患者的牙周病--一项探索性研究
IF 1.4
Acta Stomatologica Croatica Pub Date : 2024-06-01 DOI: 10.15644/asc58/2/1
Vedran Radujković, Arijana Lovrenčić-Huzjan, Ivan Puhar
{"title":"Periodontal Disease in Patients with Ischemic Stroke - an Exploratory Study.","authors":"Vedran Radujković, Arijana Lovrenčić-Huzjan, Ivan Puhar","doi":"10.15644/asc58/2/1","DOIUrl":"10.15644/asc58/2/1","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to assess the periodontal disease parameters in patients with ischemic stroke.</p><p><strong>Materials and methods: </strong>The study included 21 patients with ischemic brain stroke and a control group that was matched in number, age, and gender. All participants underwent a standard periodontal examination. The inclusion criterion of this study was the presence of at least 15 teeth. Periodontal epithelial surface area, periodontal inflamed surface area (PISA), and periodontal disease stage were determined. All participants were given a questionnaire to determine oral health-related quality of life (OHQL). Stroke risk factors were assessed.</p><p><strong>Results: </strong>Stroke patients had a significantly higher OHQL score than the control group (20.81 vs. 12.57) and a full-mouth plaque score (FMPS, 27.57 vs. 16.83), while full-mouth bleeding score (FMBS) was significantly higher in the control group than in the hospital group (10.17 vs. 6.42). For PISA, statistically significant negative correlations were found for smoking, cholesterol levels, and LDL levels, while significant positive correlations were found for FMBS, clinical attachment level and probing depth.</p><p><strong>Conclusion: </strong>Although PISA does represent the amount of periodontal tissue that is inflamed, tooth loss due to advanced periodontal disease combined with oral hygiene limitations imposed by the hospital setting and the stroke recovery process remain the most significant obstacles for a more meaningful understanding of the data represented by specific clinical, laboratory and various demographic parameters that characterize the two diseases.</p>","PeriodicalId":7154,"journal":{"name":"Acta Stomatologica Croatica","volume":"58 2","pages":"110-122"},"PeriodicalIF":1.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11256875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Sella Turcica Variations in Lateral Cephalometric Radiographs and its Association with Malocclusion. 评估头颅侧位X光片中的蝶鞍变异及其与错颌畸形的关系。
IF 1.4
Acta Stomatologica Croatica Pub Date : 2024-06-01 DOI: 10.15644/asc58/2/6
Taniya Poorsoleiman, Benyamin Kazemi, Maryam Tofangchiha, Mehdi Ranjbaran, Marjan Bolbolian, Francesco Pagnoni, Rodolfo Reda, Luca Testarelli
{"title":"Evaluation of Sella Turcica Variations in Lateral Cephalometric Radiographs and its Association with Malocclusion.","authors":"Taniya Poorsoleiman, Benyamin Kazemi, Maryam Tofangchiha, Mehdi Ranjbaran, Marjan Bolbolian, Francesco Pagnoni, Rodolfo Reda, Luca Testarelli","doi":"10.15644/asc58/2/6","DOIUrl":"10.15644/asc58/2/6","url":null,"abstract":"<p><strong>Objectives: </strong>Understanding the shape and size of the sella turcica may help predict future orthodontic treatment needs related to skeletal malocclusion. This study aims to assess different morphological types of the sella turcica in lateral cephalometric radiographs and its correlation with malocclusion, as well as the relationship between gender and linear measurements of sella turcica.</p><p><strong>Materials and methods: </strong>The lateral cephalometric radiographs of 410 volunteers (111 men and 299 women) aged 8 to 30 years were evaluated. The patients were divided into three groups based on their skeletal growth patterns (cl I, II, and III). Then the anatomical shape and linear dimensions of sella turcica were assessed. Measurements were made using Adobe Photoshop Version: 20.0.0 software, and data analysis was performed by IBM SPSS Statistics version 25.</p><p><strong>Results: </strong>The following morphologies were observed: normal (37.8%), oblique anterior wall (9.3%), double contour of the floor (21.5%), sella turcica bridge (8.8%), irregularity (notching) in the posterior part of sella turcica (16.6%), and pyramidal shape of the dorsum sellae (6.1%). No statistically significant relationship was found between sella turcica variations and skeletal malocclusion. The correlation between female sex with the diameter (p=0.027) and depth values (p=0.035) of sella turcica was statistically significant. There was no statistically significant difference (p>0.05) in length based on gender.</p><p><strong>Conclusion: </strong>The most morphological type reported was normal sella turcica (37.8%). Anatomical variations of sella turcica had no association with malocclusion. The most considerable depth and diameter of sella turcica were found in women.</p>","PeriodicalId":7154,"journal":{"name":"Acta Stomatologica Croatica","volume":"58 2","pages":"169-176"},"PeriodicalIF":1.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11256869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early Childhood Oral Health Impact Scale: Psychometric Evaluation in Portuguese Preschoolers. 幼儿口腔健康影响量表:葡萄牙学龄前儿童心理计量学评估。
IF 1.4
Acta Stomatologica Croatica Pub Date : 2024-03-01 DOI: 10.15644/asc58/1/4
Carolina Correia, Sandra Ribeiro Graça, Sónia Mendes
{"title":"Early Childhood Oral Health Impact Scale: Psychometric Evaluation in Portuguese Preschoolers.","authors":"Carolina Correia, Sandra Ribeiro Graça, Sónia Mendes","doi":"10.15644/asc58/1/4","DOIUrl":"10.15644/asc58/1/4","url":null,"abstract":"<p><strong>Objective: </strong>to contribute to the validation of the <i>Early Childhood Oral Impact Scale</i> (ECOHIS) by studying its psychometric properties when applied to a Portuguese preschool population.</p><p><strong>Methods: </strong>Cross-sectional study conducted with children aged between three and five-years-old. The non-probabilistic sample included two preschools in the municipality of Lisbon. Children who agreed to participate and whose guardians signed the informed consent were included. Data collection included a questionnaire, administered to the parents, and an intraoral examination of the children. The questionnaire included the Portuguese version of ECOHIS. The intraoral examination included the caries diagnosis according to the World Health Organization criteria. Discriminant validity compared the ECOHIS score between children with and without caries experience (Mann-Whitney U-test). Cohen's d was calculated to estimate the magnitude of the difference. Reliability analysis included Cronbach's α and test-retest. Construct validity was analyzed by the correlation between the ECOHIS score and dmft (Spearman's correlation). A significance level of 5% was used.</p><p><strong>Results: </strong>The sample included 104 children (mean age 4.1 years). ECOHIS values were significantly different between children with and without caries (p=0.004). The Cohen's d was 0.84. The Cronbach's was 0.78, with no significant increase in value when eliminating any of the items. The test-retest showed significant correlation (r=0.76; p=0.01). There was a significant correlation between the ECOHIS score and caries experience (r=0.28; p=0.004).</p><p><strong>Conclusion: </strong>The Portuguese version of the ECOHIS showed good psychometric properties, indicating that it is a reliable and valid tool to measure the impact of oral health in preschool children.</p>","PeriodicalId":7154,"journal":{"name":"Acta Stomatologica Croatica","volume":"58 1","pages":"39-51"},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10981910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140334320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding and Practices of Oral Hygiene in the Intensive Care Units: Perspectives of Medical Staff at Two University Hospital Centers. 重症监护室口腔卫生的认识与实践:两所大学医院中心医务人员的观点。
IF 1.4
Acta Stomatologica Croatica Pub Date : 2024-03-01 DOI: 10.15644/asc58/1/8
Vesna Vucelić, Vesna Bratić, Dubravka Negovetić Vranić, Arjana Tambić Andrašević, Vesna Degoricija, Zlatan Mihaljević, Snježana Ramić, Ivana Piteša Košutić, Luka Šimunović, Bruno Špiljak, Vlaho Brailo
{"title":"Understanding and Practices of Oral Hygiene in the Intensive Care Units: Perspectives of Medical Staff at Two University Hospital Centers.","authors":"Vesna Vucelić, Vesna Bratić, Dubravka Negovetić Vranić, Arjana Tambić Andrašević, Vesna Degoricija, Zlatan Mihaljević, Snježana Ramić, Ivana Piteša Košutić, Luka Šimunović, Bruno Špiljak, Vlaho Brailo","doi":"10.15644/asc58/1/8","DOIUrl":"10.15644/asc58/1/8","url":null,"abstract":"<p><strong>Objective: </strong>This study assesses the knowledge, practices, and attitudes of medical staff in intensive care units (ICUs) regarding oral hygiene care for critically ill, bedridden patients.</p><p><strong>Material and methods: </strong>A cross-sectional study included 65 employees from the Intensive Care Units of the Sestre Milosrdnice Clinical Hospital Centre (CHC SM) and the Clinic for Anesthesiology and Intensive Care at the University Clinical Hospital Centre Zagreb (CHC ZG). A self-administered questionnaire was used to assess knowledge, methods, frequency, and attitudes towards oral care for mechanically ventilated patients. The data were examined through descriptive statistical methods, presented in terms of proportions (percentages). For the purpose of comparing the feedback across the two hospital centers and different educational backgrounds, the Chi-square and Fisher's exact tests were employed.</p><p><strong>Results: </strong>Results of a survey of 65 participants (18 from CHC SM and 47 from CHC ZG) revealed a notable disparity in oral hygiene knowledge, with graduate nurses displaying the highest proportion of adequate knowledge (100%) and regular nurses showing the least (30.3%) (p<.001). Although the execution of oral care practices did not vary significantly among the groups, graduate nurses performed oral care more frequently (80% vs. baccalaureate technicians 33.33% and nurses 57.6%, three or more times a day) and demonstrated better proficiency in both mechanical (p=.005) and chemical (p<.001) biofilm management compared to their counterparts. No significant difference was observed in the delivery of oral care to orotracheally intubated patients across different educational levels (p=.127). However, a marked difference was noted in the perception of being adequately trained for such care, with nurses feeling less prepared (12.1%, p<.001). Despite these variances, all respondents recognized the importance of oral hygiene, thus showing a strong dedication to oral health care. <b>Conclusions:</b> This study highlights variability in ICU oral hygiene practices and points to the importance of standardized care protocols and improved training for healthcare staff.</p>","PeriodicalId":7154,"journal":{"name":"Acta Stomatologica Croatica","volume":"58 1","pages":"85-93"},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10981905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140334325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Grape Seed Oligomeric Proanthocyanidin and Nisin on Dental Pulp Stem Cells. 葡萄籽低聚原花青素和 Nisin 对牙髓干细胞的影响
IF 1.4
Acta Stomatologica Croatica Pub Date : 2024-03-01 DOI: 10.15644/asc58/1/1
Elif Ballikaya, Sena Babadag, Nalan Oya San Keskin, Betül Çelebi-Saltik
{"title":"The Effects of Grape Seed Oligomeric Proanthocyanidin and Nisin on Dental Pulp Stem Cells.","authors":"Elif Ballikaya, Sena Babadag, Nalan Oya San Keskin, Betül Çelebi-Saltik","doi":"10.15644/asc58/1/1","DOIUrl":"10.15644/asc58/1/1","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the biological effects of \"proanthocyanidin\" (PA), and \"nisin\" (Ni), on dental pulp stem cells (DPSCs) and LPS-induced DPSCs as well as their antimicrobial effects against <i>S. aureus</i> and <i>E. coli</i>.</p><p><strong>Materials and methods: </strong>After characterization of DPSCs, cytotoxicity of PA and Ni on DPSCs were evaluated using a water-soluble tetrazolium salt (WST-1). The cytokines and chemokines released by DPSCs and the expression levels of IL-6, IL-8, and TNF alpha were detected with human Cytokine Array C5 and enzyme-linked immunosorbent assay (ELİSA), respectively. The antibacterial activities of PA and Ni were tested using the drop plate method.</p><p><strong>Results: </strong>PA at 75 μg/ml increased cell viability, decreased TNF-α expression of DPSCs, did not show any cytotoxic effects on LPS-induced DPSCs, and also showed a tendency to decrease TNF-α expression. PA at 75 μg/ml exhibited higher expressions of TIMP-2, OPG, IL-7, and IL-8 in LPS-induced DPSCs compared to DPSCs. Ni at 100 μg/ml decreased TNF-α expression in DPSCs with no cytotoxic effects. It provided increased cell viability and a downregulation trend of TNF-α expression in LPS-induced DPSCs. Both Ni and PA provided strong antibacterial effects against <i>S. aureus</i>. Ni at 200μg/ml had strong antibacterial effects against <i>E. coli</i> without affecting negatively the viability of both DPSCs and LPS-induced DPSCs and showed anti-inflammatory activity by decreasing TNF-α expression. PA provided strong antibacterial effects against <i>E. coli</i> at 200 μg/ml but affected DPSCs viability negatively.</p><p><strong>Conclusion: </strong>PA and Ni at specific concentrations exhibited immunomodulatory activity on DPSCs and LPS-induced DPSCs without any cytotoxic effects and strong antibacterial effects on <i>S. aureus</i>.</p>","PeriodicalId":7154,"journal":{"name":"Acta Stomatologica Croatica","volume":"58 1","pages":"2-17"},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10981911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140334324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monowave vs. Polywave Light - Curing Units: Effect on Light Transmission of Composite without Alternative Photoinitiators. 单波与多波光固化装置:对无替代光引发剂的复合材料透光率的影响。
IF 1.4
Acta Stomatologica Croatica Pub Date : 2024-03-01 DOI: 10.15644/asc58/1/3
Danijela Marović, Paulina Daničić, Gloria Bojo, Matej Par, Zrinka Tarle
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