{"title":"Squamous cell carcinoma of the uterine cervix.","authors":"J E Johnsson","doi":"10.3109/02841867709133932","DOIUrl":"https://doi.org/10.3109/02841867709133932","url":null,"abstract":"<p><p>The healing among patients with squamous cell carcinoma of the uterine cervix in stages I B and II has been calculated in 189 patients from the 1950's and in 271 patients from 1969 to 1973. The observation period was 2 years. The first material was treated using the Stockholm technique. Extraperitoneal lymphadenesctomy was also performed in 59 per cent. The second material was treated with whole-pelvis irradiation using external high-voltage technique without central shielding, compelemented with intracavitary treatment using modified Stockholm applicators. The frequency of central recurrences, metastases on the pelvic wall after completion of treatment and deaths from carcinoma for stages I B and II were in material I approximately 6 and 20 per cent, approximately 8 and 14 per cent, and approximately 12 and 22 per cent, respectively; and in material II 9 and 20 per cent, 3 and 11 per cent, and 9 and 22 per cent, respectively.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"16 1","pages":"33-52"},"PeriodicalIF":0.0,"publicationDate":"1977-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867709133932","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12054626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Complications after radiation therapy for cervical carcinoma.","authors":"A Bosch, Z Frias","doi":"10.3109/02841867709133933","DOIUrl":"https://doi.org/10.3109/02841867709133933","url":null,"abstract":"<p><p>A series of 1 139 patients with invasive carcinoma of the cervix uteri who received a complete course of treatment by means of external irradiation followed by intracavitary curietherapy was evaluated in order to assess the results of treatment and, in particular, the radiation complications induced. Complications developed in 145 instances (12.7%). Severe complications occurred in only 3 per cent. Twenty-four cases had more than one complication. Rectosigmoidal injuries accounted for 72 per cent of all complications, and appeared earlier than did bladder complications and within the first two years after treatment. No apparent correlation between age and the occurrence of complications was found. The rate was higher in early stages. The radiation complications did not adversely affect the survival results.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"16 1","pages":"53-62"},"PeriodicalIF":0.0,"publicationDate":"1977-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867709133933","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12054627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of temperature on the activity of ciliated cells during exposure to ionizing radiation.","authors":"L Baldetrop, C H Håkansson, B Baldetrop","doi":"10.3109/02841867709133929","DOIUrl":"https://doi.org/10.3109/02841867709133929","url":null,"abstract":"<p><p>The influence of temperature on the early effects ionizing irradiation has been analysed using the trachea of the rabbit. ATP is assumed to be released by the effect of irradiation on the mitochondrial membranes, which increases the mucociliary activity in the epithelium, registered second-by-second during irradiation performed at 20 degrees C, 30 degrees C, 37 degrees C and 40 degrees C. The early effects of irradiation depended on the temperature, while hyperthermia does not potentiate this condition. A possible explanation is that phosphofructokinase, which is probably stimulated by irradiation, is inactivated at lower temperatures.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"16 1","pages":"17-26"},"PeriodicalIF":0.0,"publicationDate":"1977-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867709133929","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12054625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A P Andersen, K Bertelsen, O Elbrond, C Gadeberg, C Lund
{"title":"Malignant tumours of the oropharynx.","authors":"A P Andersen, K Bertelsen, O Elbrond, C Gadeberg, C Lund","doi":"10.3109/02841867709133934","DOIUrl":"https://doi.org/10.3109/02841867709133934","url":null,"abstract":"An analysis of a series of 127 patients with malignant tumours of the oropharynx is presented. All cases of epidermoid carcinoma were retrospectively classified according to the TNM system. Primary treatment consisted in irradiation in all cases of malignant lymphoma and epidermoid carcinoma. The corrected 5-year survival rate for patients with malignant lymphoma was 53 per cent, and for those with epidermoid carcinoma 40 per cent. In epidermoid carcinoma, 60Co treatment seemed to result in a better prognosis than 250 kV radiation therapy. Both in malignant lymphoma and epidermoid carcinoma, the prognosis was definitely related to the spread to regional lymph nodes.","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"16 1","pages":"63-72"},"PeriodicalIF":0.0,"publicationDate":"1977-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867709133934","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12054628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulmonary gas exchange following irradiation of cervical, mediastinal, hilar and axillary nodes.","authors":"C Lassvik, B Rosengren, B Wranne","doi":"10.3109/02841867709133930","DOIUrl":"https://doi.org/10.3109/02841867709133930","url":null,"abstract":"In the treatment of Hodgkin’s disease according to KAPLAN (1966) the cervical, mediastinal, hilar and axillary nodes are irradiated. Although as much as possible of the lung tissue is protected from irradiation there is always a potential risk of pulmonary, mediastinal and myocardial injury. LARSSON et coll. (1976) have recently investigated the effect on the cardiovascular system. They found an increased incidence of ECG abnormalities, mainly T-wave changes and atrial arrhythmias, during treatment and also a considerable fall in the arterial blood pressure in about 20 per cent of the patients. However, 6 months after treatment the abnormalities had disappeared. The effect on the pulmonary gas exchange following irradiation of the mediastinal, hilar, cervical and axillary nodes is now reported.","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"16 1","pages":"27-31"},"PeriodicalIF":0.0,"publicationDate":"1977-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867709133930","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11780194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiation therapy in Burkitt's lymphoma of the central nervous system.","authors":"T Norin","doi":"10.3109/02841867709133935","DOIUrl":"https://doi.org/10.3109/02841867709133935","url":null,"abstract":"<p><p>Involvement of the central nervous system in patients with with Burkitt's lymphoma was treated by superfractionated irradiation. The primary effect in 20 patients is reported. In 3 of 5 patients with paraplegia, complete regression was achieved. Only one patient of 6 with cranial neuropathy and irradiated to the brain improved. In 8 patients with either cranial neuropathy or other neurologic symptoms of signs, the brain and spinal cord were irradiated. Three of these patients, with recurrences after previous intrathecal chemotherapy, responded with complete regression.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"16 1","pages":"73-80"},"PeriodicalIF":0.0,"publicationDate":"1977-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867709133935","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12054629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In vivo absorption of carbohydrates in rats with gastro-intestinal radiation syndrome.","authors":"A Becciolini, G B Gerber, J Deroo","doi":"10.3109/02841867709133937","DOIUrl":"https://doi.org/10.3109/02841867709133937","url":null,"abstract":"<p><p>Absorption of glucose and sucrose by intestine from supralethally irradiated rats was investigated using an in vivo preparation. An activation of glucose absorption one day day after exposure is followed by a marked fall in glucose and sucrose absorption on day 3. Experiments under different conditions of loading indicate that at 20 hours active transport of glucose is already impaired although the maximum velocity is increased. After 3 days maximum velocity and active transport decrease markedly. Inverstase activity increases after 20 hours, but this is not accompanied by an increased sucrose absorption. The defect in sucrose absorption 72 hours after irradiation is paralleled by a decrease in invertase activity.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"16 1","pages":"87-96"},"PeriodicalIF":0.0,"publicationDate":"1977-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867709133937","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12054631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hyperthermic tumour-cell devitalization in vivo.","authors":"K Overgaard, J Overgaard","doi":"10.3109/02841867709133928","DOIUrl":"https://doi.org/10.3109/02841867709133928","url":null,"abstract":"<p><p>A review of the morphologic, biochemical and clinical effects of hyperthermia on malignant cells indicates the presence of two principally different heat-induced alterations. (1) A 'destructive' lysosomal dependent cytoplasmic reaction dominates the tumour-cell devitalization in vivo, probably influenced by the characteristic tumour cell environment. (2) 'Repressive' nuclear abnormalities may be observed, but seem to be secondary in the in vivo reaction. However, under certain conditions (combined treatment modalities) this nuclear effect may be of importance.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"16 1","pages":"1-16"},"PeriodicalIF":0.0,"publicationDate":"1977-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867709133928","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11240207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bone mineral content of the forearm in a healthy population.","authors":"P Karjalainen, E M Alhava","doi":"10.3109/02841867709134313","DOIUrl":"https://doi.org/10.3109/02841867709134313","url":null,"abstract":"<p><p>The bone mineral content in the distal radius, in the midshaft radius and ulna was measured in 83 healthy males and 89 females from 11 to 87 years old using the 241Am gamma ray attenuation method. The age distributions of different 'density' quantities characterizing bone mineral are presented and the usefulness of these quantities is discussed.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"16 2","pages":"199-208"},"PeriodicalIF":0.0,"publicationDate":"1977-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867709134313","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12053492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Xeroradiography in radiation therapy.","authors":"C Lagergren, L E Larsson","doi":"10.3109/02841867709134304","DOIUrl":"https://doi.org/10.3109/02841867709134304","url":null,"abstract":"<p><p>The xerographic technique has been introduced at Radiumhemmet for direct field control in therapy with high energy photon radiation (60Co-unit, 6 MV linear accelerator and 42 MeV betatron). The xerograms are of a sufficiently good quality for this purpose. The advantages and disadvantages connected with the xerographic facilities at present available are discussed.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"16 2","pages":"125-8"},"PeriodicalIF":0.0,"publicationDate":"1977-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867709134304","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11613348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}