Acta medica Hungarica最新文献_第5页

Lysosomal enzyme activities in frozen, non-cultured chorionic villi for prenatal diagnosis of enzymopathies. 在冷冻，非培养的绒毛膜绒毛溶酶体酶活性产前诊断酶病。

Acta medica Hungarica Pub Date : 1992-01-01

M Németh, A László, A Kovács, G Falkay

引用次数: 0

The effect of sulphonylurea therapy on the outcome of coronary heart diseases in diabetic patients. 磺脲类药物对糖尿病患者冠心病转归的影响。

Acta medica Hungarica Pub Date : 1992-01-01

G Pogatsa, M Z Koltai, G Jermendy, J Simon, Z Aranyi, G Ballagi-Pordany

{"title":"The effect of sulphonylurea therapy on the outcome of coronary heart diseases in diabetic patients.","authors":"G Pogatsa, M Z Koltai, G Jermendy, J Simon, Z Aranyi, G Ballagi-Pordany","doi":"","DOIUrl":"","url":null,"abstract":"A retrospective study was performed on 1040 diabetic patients. The survival time of those treated with first generation sulphonylureas (n = 227) was considerably (P < 0.001) shorter after the first attack of angina pectoris (5 +/- 1 years, mean +/- S.E.) or acute myocardial infarction (6 +/- 1 years) than of those (9 +/- 1 years) on glibenclamide treatment (n = 144), with regime alone (n = 282) or treated with insulin (n = 387). The systolic blood pressure of patients with first generation sulphonylureas (166 +/- 1/91 +/- 1 mmHg) proved to be higher (P < 0.01) than those treated with glibenclamide (159 +/- 1/91 +/- 1 mmHg) or being on regime alone (155 +/- 1/89 +/- 1 mmHg) or on insulin (156 +/- 1/89 +/- 1 mmHg) treatments. Serum sodium level was found to be lower (P < 0.05) in patients treated with any kind of sulphonylureas (138 +/- 1 mmol/l) than in the other patients (143 +/- 1 mmol/l). During an observation period, 576 of patients died, 412 of them due to cardiovascular or renal failures. Among the diabetic subjects suffering from coronary heart disease no difference could be detected in risk factors except for higher systolic blood pressure. The shorter survival time of patients treated with first-generation sulphonylureas might be explained by the arrhythmogenic activity of first-generation sulphonylureas. Improvement in therapy, metabolic and cardiovascular alterations during the survey can not be responsible for the shorter survival time of patients treated with first generation-sulphonylureas.","PeriodicalId":7090,"journal":{"name":"Acta medica Hungarica","volume":"49 1-2","pages":"39-51"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12469893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of atrial dilatation on reperfusion arrhythmias: development of supraventricular tachycardias on reperfusion with atrial stretching. 心房扩张对再灌注心律失常的影响:室上性心动过速的发展对心房扩张再灌注的影响。

Acta medica Hungarica Pub Date : 1992-01-01

F Solti, V Kékesi, A Juhász-Nagy

{"title":"The effect of atrial dilatation on reperfusion arrhythmias: development of supraventricular tachycardias on reperfusion with atrial stretching.","authors":"F Solti, V Kékesi, A Juhász-Nagy","doi":"","DOIUrl":"","url":null,"abstract":"Unlabelled: The study was aimed at investigating the effect of atrial dilatation on the genesis of supraventricular tachyarrhythmias following myocardial reperfusion. Experiments were carried out in 26 mongrel dogs under pentobarbital narcosis with artificial ventilation. Electrophysiological study was performed for studying the arrhythmic condition of the heart. Investigations were carried out: (i) in normal condition, (ii) during atrial stretching (balloon dilatation of the left atrium), (iii) in reperfusion following myocardial ischemia, (iv) in reperfusion combined with atrial stretching. On reperfusion the irritability of the atrium increased moderately (on atrial extrastimuli in 3 dogs non-sustained atrial tachycardia, in 7 dogs repeated atrial responses could be induced). Reperfusion with atrial stretching, however, very markedly enhanced the atrial vulnerability, and in 19 dogs atrial tachycardia appeared spontaneously. Comparison of the effect of atrial stretching to that of atrial stretching + reperfusion showed that the reperfusion significantly augmented the arrhythmia-inducing effect of atrial stretching.Clinical investigations: Aortocoronary bypass operations were followed by development of supraventricular tachycardia in 41 out of 428 operated cases. Atrial dilatation was detected in 37 cases, mostly before the appearance of atrial tachycardia. The data seem to prove that atrial dilatation has an important part in the pathogenesis of supraventricular tachyarrhythmias following reperfusion of myocardial ischemia.","PeriodicalId":7090,"journal":{"name":"Acta medica Hungarica","volume":"49 3-4","pages":"159-70"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12519245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship of serum antihistone antibody level to the patient's age. 血清抗组蛋白抗体水平与患者年龄的关系。

Acta medica Hungarica Pub Date : 1992-01-01

A Lakatos, J Sétáló, K Jobst, A Pár

引用次数: 0

Effect of vitamin E on the immunoreactivity of spleen cells in hyperlipidaemic rats. 维生素E对高脂血症大鼠脾细胞免疫反应性的影响。

Acta medica Hungarica Pub Date : 1992-01-01

R González-Cabello, A Blázovics, M E Horváth, G Müzes, P Gergely, J Fehér

引用次数: 0

Is the incidence of acute mountain sickness (AMS) at medium altitude in the Austrian Alps influenced by the height of home residence of the alpinist? 奥地利阿尔卑斯山区中海拔地区急性高山病(AMS)的发病率是否受登山者居住地高度的影响?

Acta medica Hungarica Pub Date : 1992-01-01

G Röggla, A Wagner, M Röggla

引用次数: 0

Porphyrin studies in chronic renal failure and renal transplantation. 卟啉在慢性肾功能衰竭和肾移植中的研究。

Acta medica Hungarica Pub Date : 1992-01-01

M M el-Sharabasy

引用次数: 0

Anticardiolipin antibodies: association with anti-DNA antibodies, disease activity, renal involvement and a history of thrombosis in systemic lupus erythematosus. 抗心磷脂抗体:与系统性红斑狼疮的抗dna抗体、疾病活动性、肾脏受累和血栓史相关

Acta medica Hungarica Pub Date : 1992-01-01

R Reul, J Kádár, I Bodó, P Gergely

引用次数: 0

Clinical utility of quantitative assessment of liver haemodynamics in cirrhosis provided by dynamic hepatoscintigraphy. 动态肝显像定量评估肝硬化肝血流动力学的临床应用。

Acta medica Hungarica Pub Date : 1992-01-01

M Hartleb, T Kloc, A Becker, I Mańczyk, H Bołdys

{"title":"Clinical utility of quantitative assessment of liver haemodynamics in cirrhosis provided by dynamic hepatoscintigraphy.","authors":"M Hartleb, T Kloc, A Becker, I Mańczyk, H Bołdys","doi":"","DOIUrl":"","url":null,"abstract":"Interrelationships between quantitative assessment of portal (%Qp) and arterial (%Qa) components of hepatic blood supply obtained by dynamic hepatoscintigraphy, and clinical variables characterizing the severity of liver cirrhosis and portal hypertension were studied in 25 cirrhotic patients. The variables, clinical state, size of oesophageal varices, ascites accumulation, sonographic stigmata of portal hypertension, liver mass and elimination rate of lidocaine and antipyrine were studied. The %Qa rose in proportion to the severity of liver injury estimated from the Child-Turcotte and McCormick grading scores. The mean %Qa for patients with Child A cirrhosis was significantly higher than that for 8 healthy subjects (34.8 +/- 7.9% vs 18.1 +/- 4.0; P < 0.01). The %Qp values showed relationship with the size of esophageal varices, provided discriminatory data with respect to the ascitic fluid accumulation and the development of intraabdominal collateral circulation. The liver mass had no impact on hepatic dual blood supply pattern, but was linked with the rate of antipyrine clearance. Neither antipyrine clearance nor lidocaine elimination rate corresponded to alterations of hepatic dual blood supply. The %Qp showed a negative correlation with the initial half-life of lidocaine, which was referred to lowered hepatic uptake of the drug. It is concluded that the quantitative assessment of %Qp and %Qa reflect the advancement of portal hypertension better than liver function failure does.","PeriodicalId":7090,"journal":{"name":"Acta medica Hungarica","volume":"49 1-2","pages":"17-28"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12469891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Macroethical responsibilities of societies of gynaecologists and obstetricians. 妇产科医师协会的宏观伦理责任。

Acta medica Hungarica Pub Date : 1992-01-01

R J Cook, L G Lampé

{"title":"Macroethical responsibilities of societies of gynaecologists and obstetricians.","authors":"R J Cook, L G Lampé","doi":"","DOIUrl":"","url":null,"abstract":"The theme of maternal mortality and morbidity is of transcending macroethical importance. High rates of maternal mortality and morbidity can be significantly reduced by cost-effective means that are not dependent on advanced biotechnology. It has been shown that a major cause of maternal mortality comes from women (i) bearing children too early or too late in their reproductive lives, (ii) too frequently or at insufficiently spaced intervals. If women were able to control their fertility in order not to have children at unwanted times in periods of their life when pregnancy is inimical to their health, the incidence of maternal mortality and morbidity would drop. Improved standards of women's education, both in general and in particular regarding women's reproductive health, would reinforce the understanding of how to protect and improve one's reproductive health, and would accelerate the decline of maternal mortality and chronic morbidities. Accordingly, the macroethical demands of respect for autonomy, beneficence and justice would coincide. The value of justice would be served not only regarding women themselves, particularly those who have traditionally been vulnerable by virtue of their growing age, or dependent status in their communities, but also regarding the children dependent on such women, and families also dependent on the services of such women, like mothers, wives, daughters and grand-daughters.","PeriodicalId":7090,"journal":{"name":"Acta medica Hungarica","volume":"49 1-2","pages":"3-16"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12469892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0