维生素E对高脂血症大鼠脾细胞免疫反应性的影响。

Acta medica Hungarica Pub Date : 1992-01-01

R González-Cabello, A Blázovics, M E Horváth, G Müzes, P Gergely, J Fehér

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引用次数: 0

摘要

致动脉粥样硬化(富含脂质)饮食抑制大鼠丝裂原诱导的淋巴细胞成母反应。补充维生素E完全消除了饮食的抑制作用。致动脉粥样硬化饮食也降低了脾脏巨噬细胞产生的肿瘤坏死因子α (tnf - α)活性，然而，补充维生素E未能消除这种影响。饮食或补充对巨噬细胞白细胞介素-1 (IL-1)的产生没有可测量的作用。

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Effect of vitamin E on the immunoreactivity of spleen cells in hyperlipidaemic rats.

Atherogenic (lipid-rich) diet suppressed mitogen-induced lymphocyte blastogenic responses in rats. Supplementation with vitamin E completely abolished the suppressive effect of the diet. The atherogenic diet also decreased the tumour necrosis factor alpha (TNF-alpha) activity produced by spleen macrophages, however, vitamin E supplementation failed to abolish this effect. Diet or supplementation had no measurable action on interleukin-1 (IL-1) production of macrophages.

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来源期刊

Acta medica Hungarica

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