Acta hepato-gastroenterologica最新文献_第4页

Histochemical, immunological, electron microscopic study in HBsAg patients with liver diseases and healthy carriers. 肝病患者与健康乙肝表面抗原携带者的组织化学、免疫学、电镜研究。

Acta hepato-gastroenterologica Pub Date : 1979-10-01

C Surrenti, V Anselmucci, G Bianchini, A Casini, D Ramarli, G Salvadori, P Gentilini

引用次数: 0

Binding sites for endotoxic lipopolysaccharide on the plasma membrane of isolated rabbit hepatocytes. 离体兔肝细胞质膜上内毒素脂多糖的结合位点。

Acta hepato-gastroenterologica Pub Date : 1979-10-01

G Ramadori, U Hopf, K H Meyer zum Büschenfelde

{"title":"Binding sites for endotoxic lipopolysaccharide on the plasma membrane of isolated rabbit hepatocytes.","authors":"G Ramadori, U Hopf, K H Meyer zum Büschenfelde","doi":"","DOIUrl":"","url":null,"abstract":"The in vitro fixation of bacterial lipopolysaccharide (LPS) on the plasma membrane of mechanically or enzymatically isolated hepatocytes from rabbits was studied by immunofluorescence technique. Antisera against LPS from E. coli 026:B6 and 0111:B4 were induced in rabbits. Antibody titers up to 1:1024 were determined by the passive hemagglutination test. There was no immunologic cross reactivity between the two antisera. IgG and IgM were prepared from anti-LPS as well as from normal rabbit serum and conjugated with fluorescein-isothiocyanate. The antibody activity against LPS was localized in the IgM fraction. Hepatocytes were isolated by a perfusion technique without enzymes and with collagenase. LPS binding to the hepatocellular plasma membrane increased proportionally with the LPS concentration in a range between 0.01 and 1.0 mg per ml. The fluorescence pattern of the membrane fixed IgM anti-LPS-antibody at the surface of LPS coated hepatocytes was coarse granular. The in vitro reaction of LPS with hepatocytes was not influenced by the presence of complement. The demonstration of binding sites for LPS on the hepatocellular plasma membrane supports the hypothesis that not only Kupffer cells but also parenchymal liver cells are involved in the hepatic clearance activity for endotoxin.","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 5","pages":"368-74"},"PeriodicalIF":0.0,"publicationDate":"1979-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11600767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The action of potato inhibitors on activation of zymogen forms of digestive system proteases. 马铃薯抑制剂对消化系统蛋白酶酶原形式激活的作用。

Acta hepato-gastroenterologica Pub Date : 1979-10-01

K Worowski, A Gabryelewicz, W Roszkowska, K Bajko

引用次数: 0

Pneumatosis cystoides intestinalis. A statistical study of 919 cases. 肠囊性肺肿。919例病例的统计研究。

Acta hepato-gastroenterologica Pub Date : 1979-10-01

J Jamart

引用次数: 0

Hepatitis-associated antigen in patients with liver diseases and in rural population of Iran. Increased incidence in men. 肝脏疾病患者和伊朗农村人口中的肝炎相关抗原男性发病率增加。

Acta hepato-gastroenterologica Pub Date : 1979-10-01

F Borhanmanesh, N Behforouz, M Sanadizadeh, M Soleimani

引用次数: 0

The effect of salbutamol and propranolol on pentagastrin, histamine and meal-stimulated acid and pepsin secretion in the dog. 沙丁胺醇和心得安对狗胃泌素、组胺和餐后刺激酸和胃蛋白酶分泌的影响。

Acta hepato-gastroenterologica Pub Date : 1979-10-01

R F McCloy, V A Dawson, J H Baron

引用次数: 0

Follow-up study on patients with non-alcoholic and non-diabetic fatty liver. 非酒精性和非糖尿病性脂肪肝患者的随访研究。

Acta hepato-gastroenterologica Pub Date : 1979-08-01

S Massarrat, G Jordan, G Sahrhage, K Asholt, P Schmitz-Moormann, J C Bode

引用次数: 0

Efficient treatment of gastric ulcer with proglumide (Milid) in outpatients (double blind trial). 丙谷氨酰胺(米利德)有效治疗门诊患者胃溃疡(双盲试验)。

Acta hepato-gastroenterologica Pub Date : 1979-08-01

S E Miederer, H Lindstaedt, K Kutz, R Mayershofer

{"title":"Efficient treatment of gastric ulcer with proglumide (Milid) in outpatients (double blind trial).","authors":"S E Miederer, H Lindstaedt, K Kutz, R Mayershofer","doi":"","DOIUrl":"","url":null,"abstract":"Eleven male and five female gastric ulcer outpatients as well as twenty eight male and seven female duodenal ulcer outpatients received Proglumide (1200 mg/day) or magnesiumtrisilicate (1320 mg/day) in a prospective double blind study. The sizes of the ulcers were assessed by endoscopy before and after 4 weeks therapy. A complete healing of gastric ulcers was observed in 75% (n = 8) of the patients receiving Proglumide and 25% (n = 8) of the antacid treated controls (p less than 0.05; x2 test). The healed area was significantly (p less than 0.05) larger in the Proglumide 91 mm2) than in the anticida group (23 mm2). In addition, the half time of the ulcer-healing was significantly (p less than 0.05) shorter in the Proglumide treated patients (18 days and 26 days respectively). There was no significant effect of the drug on the duodenal ulcers. The spontaneous healing rate was 61% in the antacid (n = 18) and 59% in the Proglumide treated (n = 17) patients. The drug does not effect the basal and pentagastrin stimulated gastric secretion nor the serum gastrin concentration. No side effects on blood pressure, blood cell count, transaminases or blood glucose concentrations could be observed.","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 4","pages":"314-8"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11594014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of ethanol ingestion on plasma biochemistry and the pancreas in the rat. 乙醇摄入对大鼠血浆生化及胰腺的影响。

Acta hepato-gastroenterologica Pub Date : 1979-08-01

S N Joffe, M M Ferrie, R O'Hare

引用次数: 0

Acute hemorrhagic pancreatic necrosis in mice: lack of a pathogenetic role for complement. 小鼠急性出血性胰腺坏死:补体缺乏致病作用。

Acta hepato-gastroenterologica Pub Date : 1979-08-01

R H Kelly, K N Rao, V S Harvey, B Lombardi

{"title":"Acute hemorrhagic pancreatic necrosis in mice: lack of a pathogenetic role for complement.","authors":"R H Kelly, K N Rao, V S Harvey, B Lombardi","doi":"","DOIUrl":"","url":null,"abstract":"Feeding a choline-deficient diet containing 0.5% DL-ethionine induces an acute hemorrhagic pancreatitis in 100% of young female mice. Evidence for deposition of the third component of complement (C3) on acinar cell plasma membranes was sought, during the inductive stages, by a sandwich immunofluorescence technique. Such a localization could not be demonstrated even though the method is capable of detecting less than 8 x 10(-5) microgram of protein/mm2 of cell membrane. Artifactual binding of immunoglobulin reagents was encountered when goat antisera, with high levels of circulating immune complexes, formed the middle layer in the sandwich technique. This was attributed to the appearance of Fc receptors on the plasma membrane of degenerating acinar cells, and could be avoided by ultracentrifuging acinar cells, and could be avoided by ultracentrifuging the goat antisera prior to sue. In view of the fact that C3 cleavage represents an amplification loop in both the calssical and alternate pathways of complement activation, the lack of demonstrable C3 staining in tbe present experiments strongly suggests that complement plays no role in acinar cell necrosis in this model of pancreatitis.","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 4","pages":"302-9"},"PeriodicalIF":0.0,"publicationDate":"1979-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11311815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0