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Acta hepato-gastroenterologica最新文献

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Fasting serum gastrin in primary hyperparathyroidism and in chronic hypercalcemia. 原发性甲状旁腺功能亢进和慢性高钙血症的空腹血清胃泌素。
Acta hepato-gastroenterologica Pub Date : 1979-12-01
I Vantini, L Cominacini, A Ederle, G Galvanini, W Piubello, S Adami, G Cavallini, V Lo Cascio
{"title":"Fasting serum gastrin in primary hyperparathyroidism and in chronic hypercalcemia.","authors":"I Vantini,&nbsp;L Cominacini,&nbsp;A Ederle,&nbsp;G Galvanini,&nbsp;W Piubello,&nbsp;S Adami,&nbsp;G Cavallini,&nbsp;V Lo Cascio","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In order to investigate the frequency of fasting hypergastrinaemia in primary hyperparathyroidism (A) and in chronic hypercalcaemia (B), in 40 and 16 patients respectively gastrin, parathyroid hormone (PTH) and serum calcium levels were measured and compared with those of a control group (40 subjects) with similar distribution of sex and age. Moreover, possible linear relationships between these parameters were investigated. Notwithstanding significant differences in calcium and PTH levels between the three groups (A: high PTH, high Ca++; B: low PTH, high Ca++; C: normal PTH and Ca++ levels), no significant difference in gastrin levels were found. However, in the first group, a marked increase of gastrin was observed in one patient, very probably affected by a gastrin-secreting tumor (positive secretin test). While no linear relationship between PTH and gastrin values was present in all the three groups, a significant correlation between serum calcium and fasting gastrin was detectable in the group A, ruling-out the above mentioned patient. Present data suggest that PTH does not modify gastrin levels and that chronic moderate hypercalcaemia does not raise serum fasting gastrin, at least in clinical conditions. Moreover, the frequency of hypergastrinaemia in hyperparathyroidism is very low and it seems to be present only in patients with gastrin-secreting tumors.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 6","pages":"472-7"},"PeriodicalIF":0.0,"publicationDate":"1979-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11754039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differential diagnosis, laboratory tests and histology in 245 patients with cholestasis. 245例胆汁淤积症的鉴别诊断、实验室检查和组织学分析
Acta hepato-gastroenterologica Pub Date : 1979-10-01
M Stajić, J Milosavljević, A Begić-Janev
{"title":"Differential diagnosis, laboratory tests and histology in 245 patients with cholestasis.","authors":"M Stajić,&nbsp;J Milosavljević,&nbsp;A Begić-Janev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the course of 4 years, among 11,738 admissions there were 245 (2.08%) patients with cholestasis (106 women and 139 men). Intrahepatic cholestasis (i.c.) was detected in 46.5%, and extrahepatic (e.c.) in 53.5%. The most frequent cause of i.c. were alcoholic and nonalcoholic chr. liver disease (fatty liver, chr. hepatitis, cirrhosis) (37% and 30%), acute viral hepatitis (15%) and toxic liver injury (14%) respectively. The causes of e.c. were: choledocholithiasis (44%), cancer of the pancreatic head (15%), cancer of gallbladder and extrahepatic ducts (12%) and cancer of liver (10%). The causes of c. were benigne, in 78.2%, while malignant neoplasms were present in 21.8%. Out of the multitude of laboratory tests two appeared particularly significant: glut, transpeptidase was pathologic in 81% of alcoholic liver disease, in 62% of the cases with obstructive jaundice and in 27.7% of malignant neoplasms. LX-lipoprotein examined in 52 patients was positive in 24% of i.c., and 60% of e.c. Proliferation of bile ducts was the most frequent finding in surgical liver biopsies in choledocholithiasis cases.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 5","pages":"375"},"PeriodicalIF":0.0,"publicationDate":"1979-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11729551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of somatostatin on the absorption of triglycerides in partially gastrectomized subjects. 生长抑素对部分胃切除术患者甘油三酯吸收的影响。
Acta hepato-gastroenterologica Pub Date : 1979-10-01
G Hengl, J Prager, H Pointner
{"title":"The influence of somatostatin on the absorption of triglycerides in partially gastrectomized subjects.","authors":"G Hengl,&nbsp;J Prager,&nbsp;H Pointner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serum triglyceride levels were measured in 10 partially gastrectomized patients after an oral fat load of 100 g. Postprandial triglyceride elevation was completely blocked by somatostatin infusion. This depression cannot be an effect of delayed gastric emptying, because all our patients were Billroth-II operated, but is considered to be due to a direct effect of somatostatin of intestinal absorption.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 5","pages":"392-5"},"PeriodicalIF":0.0,"publicationDate":"1979-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11729553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Secondary malignant tumors accompanied by primary hepatocellular carcinoma. 继发性恶性肿瘤伴原发性肝细胞癌。
Acta hepato-gastroenterologica Pub Date : 1979-10-01
T Riesz, J M Jákó, J Juhász
{"title":"Secondary malignant tumors accompanied by primary hepatocellular carcinoma.","authors":"T Riesz,&nbsp;J M Jákó,&nbsp;J Juhász","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The occurrence of liver cirrhosis and PHC cases were analyzed from the autopsy material of three hospitals. In the course of this work 13,369 autopsy reports were examined. In 339 cases liver cirrhosis was established, the frequency of association with PHC was 19.4% (66 cases). Out of 66 PHC cases 17 (25.6%) were associated with a secondary malignant tumor. This number is 10 times greater than that of other tumors of epithelial origin. It also exceeds the enlarged number of linked secondary tumors as shown in the case of certain lymphoproliferative diseases.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 5","pages":"364-7"},"PeriodicalIF":0.0,"publicationDate":"1979-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11445472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of glucagon on the blood levels of gastrin, insulin and glucose in patients with gastric and duodenal ulcers. 胰高血糖素对胃溃疡和十二指肠溃疡患者胃泌素、胰岛素和葡萄糖水平的影响。
Acta hepato-gastroenterologica Pub Date : 1979-10-01
W Tkaczewski, J Chojnacki, Z Bogoniowska
{"title":"The effect of glucagon on the blood levels of gastrin, insulin and glucose in patients with gastric and duodenal ulcers.","authors":"W Tkaczewski,&nbsp;J Chojnacki,&nbsp;Z Bogoniowska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The blood serum levels of gastrin and insulin and arterial blood levels of glucose were determined immediately before intravenous injection of 1 mg of glucagon, and 10, 20, 40 and 60 minutes later in 12 gastric ulcer patients, 14 duodenal ulcer patients and 12 controls using the radioimmunological and orthotoluidine methods respectively. Following glucagon administration the gastrin levels dropped in the controls and the gastrin patients, and increased in the duodenal patients by an average of 30%. Insulin levels increased in all three groups, but the increase was statistically significant in the two patients groups. Glucose levels in the blood also increased with no significant differences between the groups. It is suggested that the different effect of glucagon on gastrin levels may be due to gastrin-insulin interaction; the levels of the two hormones in the blood of duodenal patients were higher than in the other two groups studied.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 5","pages":"396-8"},"PeriodicalIF":0.0,"publicationDate":"1979-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11729555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acid secretion and mucosal cyclic nucleotide content of the guinea pig isolated stomach during bethanechol stimulation. 豚鼠离体胃在乙二酚刺激下的酸分泌和粘膜环核苷酸含量。
Acta hepato-gastroenterologica Pub Date : 1979-10-01
S P Canfield, B P Curwain, C Price
{"title":"Acid secretion and mucosal cyclic nucleotide content of the guinea pig isolated stomach during bethanechol stimulation.","authors":"S P Canfield,&nbsp;B P Curwain,&nbsp;C Price","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Acid secretion and mucosal cyclic AMP and cyclic GMP content of guinea pig isolated stomach preparations were measured at various times after stimulation with bethanechol (1.7 X 10(-5) M). Significant increases in acid secretion were observed without changes in cyclic nucleotides. Pre-incubation of the tissues with theophylline (10(-3) M) increased acid secretion and nucleotide content. An additional increase in acid secretion was then obtained with bethanechol in these tissues but without further change in nucleotides. Carbachol (30 micrograms/kg) administered by interperitoneal injection to conscious guinea pigs also failed to change gastric mucosal cyclic nucleotides when the animals were sacrificed 15 min later. These results are discussed in relation to the mechanisms of cholinergic stimulation of gastric acid secretion.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 5","pages":"388-91"},"PeriodicalIF":0.0,"publicationDate":"1979-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11445396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum amino acids in hepatic encephalopathy--effects of branched chain amino acid infusion on serum aminogram. 肝性脑病血清氨基酸——支链氨基酸输注对血清氨基酸图的影响。
Acta hepato-gastroenterologica Pub Date : 1979-10-01
A Watanabe, A Takesue, T Higashi, N Nagashima
{"title":"Serum amino acids in hepatic encephalopathy--effects of branched chain amino acid infusion on serum aminogram.","authors":"A Watanabe,&nbsp;A Takesue,&nbsp;T Higashi,&nbsp;N Nagashima","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Encephalopathic patients with cirrhosis of the liver consistently showed elevated levels of the aromatic amino acids, phenylalanine, tyrosine and free tryptophan as well as methionine in serum, whereas levels of the branched chain amino acids, valine, leucine and isoleucine, were depressed. Comatose patients with fulminant hepatitis had markedly elevated levels of all amino acids, the results being greatly different from those of cirrhotic patients. Molar ratios of (valine + leucine + isoleucine)/(phenylalanine + tyrosine) decreased both in cirrhotics with and without encephalopathy and in cases with fulminant hepatitis. Infusion of a commercially available L-amino acid solution in a cirrhotic patient induced a strikingly abnormal aminogram documented in hepatic encephalopathy. Therefore, effects of branched chain amino acid infusion on the deranged amino acid pattern were primarily studied for the purpose of improvement in hepatic encephalopathy by normalization of serum amino acid patterns. Elevated levels of the aromatic amino acids and methionine could be apparently depressed in a cirrhotic patient by this type of infusion but not in a case of fulminant hepatitis probably because of the poor utilization of these amino acids in severely impaired liver.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 5","pages":"346-57"},"PeriodicalIF":0.0,"publicationDate":"1979-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11729629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Achlorhydria and benign gastric ulcer. 胃酸过少和良性胃溃疡。
Acta hepato-gastroenterologica Pub Date : 1979-10-01
J A Whitaker, A R Cooke
{"title":"Achlorhydria and benign gastric ulcer.","authors":"J A Whitaker,&nbsp;A R Cooke","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 76 year-old man with a benign gastric ulcer and pernicious anemia is reported. The etiology of the ulcer is unexplained.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 5","pages":"417-8"},"PeriodicalIF":0.0,"publicationDate":"1979-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11729341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parotid salivary gland function in patients with exocrine pancreatic insufficiency. 外分泌胰腺功能不全患者的腮腺涎腺功能。
Acta hepato-gastroenterologica Pub Date : 1979-10-01
K E McColl, M J Brodie, R Whitesmith, K F Gray, T J Thomson
{"title":"Parotid salivary gland function in patients with exocrine pancreatic insufficiency.","authors":"K E McColl,&nbsp;M J Brodie,&nbsp;R Whitesmith,&nbsp;K F Gray,&nbsp;T J Thomson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Parotid function tests were performed on 12 patients with pancreatic insufficiency due to chronic pancreatitis. The concentrations of sodium and bicarbonate in stimulated parotid juice were reduced compared to controls (p less than 0.001). The secretion of 75Se-selenomethionine by the parotid salivary gland and exocrine pancreas following a Lundh test meal was measured in 12 patients with normal pancreatic function and 16 patients with exocrine pancreatic insufficiency. Eight of these patients had chronic pancreatitis both parotid and pancreatic secretion of the isotope were impaired. In pancreatic carcinoma the pancreatic excretion was impaired with no significant impairment of parotid secretion. The combined pancreatic/parotid radio-selenium test may be useful in differentiating between chronic pancreatitis and pancreatic carcinoma as the cause of pancreatic insufficiency.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 5","pages":"407-12"},"PeriodicalIF":0.0,"publicationDate":"1979-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11729557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Value of electron microscopy in gastroenterology. 电子显微镜在胃肠病学中的价值。
Acta hepato-gastroenterologica Pub Date : 1979-10-01
J F Riemann
{"title":"Value of electron microscopy in gastroenterology.","authors":"J F Riemann","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 5","pages":"343-5"},"PeriodicalIF":0.0,"publicationDate":"1979-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11729627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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