TMR整合医学最新文献

{"title":"Using simulation in complementary medicine education: an overview of clinical trials","authors":"Tamer Aboushanab, Saad Baslom, Monear Qoqandi","doi":"10.53388/tmrim202206014","DOIUrl":"https://doi.org/10.53388/tmrim202206014","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70828753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facial characteristics and Mizaj","authors":"Hamidreza Sheikh, Romina Negari, F. Ghadimi, Romina Sheikh, Zohreh Poorahmadi, R. Mirkazemi","doi":"10.53388/tmrim202206021","DOIUrl":"https://doi.org/10.53388/tmrim202206021","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70829419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the effect of Radix Bupleuri (Bupleurum chinense DC) on nonalcoholic fatty liver disease based on network pharmacology","authors":"Xu He, Ye Jiang, Kui Wang","doi":"10.53388/tmrim202206016","DOIUrl":"https://doi.org/10.53388/tmrim202206016","url":null,"abstract":"Objective : To investigate the main effects of Radix Bupleuri (Chinese name called Chai Hu) in the prevention and improvement of nonalcoholic fatty liver disease using network pharmacology techniques. Methods : We used the Traditional Chinese Medicine Systematic Pharmacology database to query the main active ingredients of Radix Bupleuri; used the DisGenet database, Treatment Target Database, and DrugBank Database to screen the targets of nonalcoholic fatty liver disease; used the matching traditional Chinese medicine-disease targets to build the traditional Chinese medicine-component-target network system using Cytoscape software; used STRING software to build the protein protein interaction system and visualized the data; DAVID database was used for gene ontology functional enrichment study and Kyoto Encyclopedia of Genes and Genomes pathway study. Results : Twelve major functional components and 175 targets have been obtained for the prevention and alleviation of nonalcoholic fatty liver disease in Radix Bupleuri; network pharmacology also confirmed the maximum degree value of kaempferol, the main active component of Radix Bupleuri; gene ontology functional enrichment analysis obtained the top 10 entries of biological process, cellular component, molecular function and Kyoto Encyclopedia of Genes and Genomes pathway analysis obtained the top 30 entries of the signalling pathway. Conclusion : Radix Bupleuri may use Fluid shear stress and atherosclerosis, Cancer, Advanced glycation end-(receptor of advanced glycation, interleukin 17, Hepatitis B, Toxoplasmosis, Relaxin, and tumor necrosis factor signalling pathway to regulate the inflammatory response of interleukin 6, tumor necrosis factor, and prostaglandin endoperoxide synthase2 targets and reduce extracellular matrix deposition to improve the therapeutic effect of Nonalcoholic fatty liver disease. And the active ingredient of traditional Chinese medicine Radix Bupleuri, kaempferol, may also play a significant role in this.","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70829148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the mechanism of Xingnao Kaiqiao acupuncture method for ischemic stroke based on EEG dynamic changes: a study protocol of an exploratory, prospective, interventional trial","authors":"Guixia Li, Lin Wu, Kaixuan Li, Fan Xu, Jia-Rong Wu, Li-Li Zhao, Haoqiang Guo, Ting Zhu","doi":"10.53388/tmrim202206033","DOIUrl":"https://doi.org/10.53388/tmrim202206033","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70829972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate effect of fomentation on pulmonary function in patient with bronchial asthma: a case series","authors":"Yogapriya Chidambaram, V. Vijayakumar, Deenadayalan Boopalan, Akila Arjunan, P. Ravi, Maheshkumar Kuppusamy","doi":"10.53388/tmrim202206018","DOIUrl":"https://doi.org/10.53388/tmrim202206018","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70829216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing evidence-based medicine in Persian medicine: obstacles, challenges, and solutions","authors":"Fataneh Hashem-Dabaghian, Aida Asghari, M. Qaraaty","doi":"10.53388/tmrim202206027","DOIUrl":"https://doi.org/10.53388/tmrim202206027","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70829335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ayurveda daily regimen practices (Dinacharya): a scientific system model approach suitable as a quaternary prevention strategy for non-communicable diseases","authors":"Vijay Kumar, Varnika Singh, Shalini Rai","doi":"10.53388/tmrim202206020","DOIUrl":"https://doi.org/10.53388/tmrim202206020","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70829475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reports of clinical trial protocols of coronavirus disease 2019: a systematic review","authors":"R. Qiu, Xuxu Wei, Meng-zhu Zhao, Changming Zhong, Chen Zhao, Jia-yuan Hu, Min Li, Ya Huang, Song-jie Han, Tianmai He, Jing Chen, H. Shang","doi":"10.53388/tmrim202206005","DOIUrl":"https://doi.org/10.53388/tmrim202206005","url":null,"abstract":"Background: To examine the outcomes heterogeneity of clinical trial protocols of coronavirus disease 2019 (COVID-19) to prioritize the establishment of a core outcome set. Methods: Databases of the International Committee of Medical Journal Editors - accepted clinical trial registry platforms were searched on February 14, 2020 and May 31, 2020. Randomized controlled trials and non-randomized controlled trials of COVID-19 were considered. Patient condition was classified as common, severe, or critical. Interventions included traditional Chinese medicine and Western medicine. We excluded trials that involved discharged patients, psychological intervention, and complications of COVID-19. The general information and outcomes, outcome measurement instruments, and measurement times were extracted. The results were analyzed by descriptive analysis. Results: In all, 19 registry platforms were searched. A total of 97 protocols were selected from among 160 protocols for the first search. For protocols of traditional Chinese medicine clinical trials, 76 outcomes from 16 outcome domains were reported, and almost half (34/76, 44.74%) of the outcomes were reported only once;the most frequently reported outcome was time taken for severe acute respiratory syndrome coronavirus 2 RNA to become negative. Twenty-seven (27/76, 35.53%) outcomes provided one or more outcome measurement instruments. Ten outcomes provided one or more measurement time frame. For protocols of Western medicine clinical trials, 126 outcomes from 17 outcome domains were reported;almost half (62/126, 49.21%) of the outcomes were reported only once;the most frequently reported outcome was proportion of patients with negative severe acute respiratory syndrome coronavirus 2. Twenty-seven outcomes provided one or more outcome measurement instruments. Forty (40/126, 31.75%) outcomes provided one or more measurement time frame. There were > 40 duplicated outcomes between the clinical trials protocols of traditional Chinese medicine and western medicine protocols. All of them were included in the Delphi survey when developing core outcome set for COVID-19. A total of 1,027 protocols were selected from 2,741 protocols for the second search. Forty-two new outcomes and 47 new outcome measurement instruments were reported. Conclusion: Outcome reporting in clinical trial protocols of COVID-19 is inconsistent. Thus, establishing a core outcome set is necessary for diagnosis and management.","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70828924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic review /meta-analysis re-evaluation of clinical effects of total glucosides of paeony in the treatment of rheumatoid arthritis","authors":"Shuang Yang, Sulan Zhang, Yanqin Wang, Yawen Liu, Jiaxuan Liu, Q. Meng, Jun Ma","doi":"10.53388/tmrim202206029","DOIUrl":"https://doi.org/10.53388/tmrim202206029","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70829380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Up-regulation of oxidative stress and inflammation in the brain of albino wistar rats following sub-acute administration of Synclisia scabrida root extract","authors":"E. Modo, Ijeoma Nina Eke, Utibe Evans Basssy, A. C. Nnamudi, E. Akpakpan, O. Etim, I. Wopara, Prosper Great Legborsi","doi":"10.53388/tmrim202206030","DOIUrl":"https://doi.org/10.53388/tmrim202206030","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70829448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}