Acta physiologica Academiae Scientiarum Hungaricae最新文献_第8页

Effect of the beta-receptor blocker pindolol on survival in HgCl2 induced acute renal failure in dogs. 受体阻滞剂品多洛尔对HgCl2诱导的犬急性肾功能衰竭存活的影响。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01

J Siklós, K Gaál

引用次数: 0

Metabolic and vascular volume oscillations in the cat brain cortex. 猫脑皮层的代谢和血管体积振荡。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01

E Dóra, A G Kovách

引用次数: 0

Effect of cyclophosphamide on the acute phase of experimental myocardial infarction in rats. 环磷酰胺对大鼠实验性心肌梗死急性期的影响。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01

I Leprán, M Koltai, L Szekeres

引用次数: 0

Pharmacological responses by different portions of guinea pig vas deferens circular muscle preparation. 豚鼠输精管环形肌制剂不同部位的药理作用。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01

E Minker, C Bartha

{"title":"Pharmacological responses by different portions of guinea pig vas deferens circular muscle preparation.","authors":"E Minker, C Bartha","doi":"","DOIUrl":"","url":null,"abstract":"The different segments of the guinea pig vas deferens circular muscle exhibit differential response patterns upon pharmacological stimulation. Namely, apart from barium chloride, the affinity and intrinsic activity of certain agonists and the strength of maximum contractions they induce appear to decrease along the path from the epididymis toward the prostate. If one subdivides the vas deferens into 3 parts of equal length such as epididymal, medial and prostatic portions, then adrenaline, acetylcholine, acetyl-beta-methylcholine, dopamine, histamine and bradykinin induce contractions on each of the 3 parts; whereas tyramine, ephedrine elicit responses in the epididymal and medial portions; amphetamine, DMPP, serotonin and PGF2 alpha in turn provoking contractions exclusively on the epididymal portion. The effects of adrenaline and noradrenaline are blocked by phentolamine and tolazoline; the responses to acetylcholine, acetyl-beta-methylcholine and carbamyl-beta-methylcholine are antagonized by atropine over a specific concentration range. The effects of tyramine, ephedrine and amphetamine are inhibited by phentolamine in an remarkably low dose range (pA2 = 13.51 +/- 0.09; 14.54 +/- 0.31; 14.35 +/- 0.12). The situation was the same when tyramine-dibenamine and tyramine-phenoxybenzamine combinations were tested (pD'2 = 14.03 +/- 0.37; 13.26 +/- 0.03). Based on these findings the presence of a peculiar alpha adrenergic receptor is suggested on the sympathetic postganglionic fibres. In addition to the already identified alpha adrenergic, muscarinic cholinergic and histamine H1 receptors, we could show the presence of dopaminergic receptors too in the vas deferens circular muscle.","PeriodicalId":7049,"journal":{"name":"Acta physiologica Academiae Scientiarum Hungaricae","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17188910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative analysis of lipase and amylase secreted into pancreatic juice and plasma volume in the rat. 大鼠胰液分泌脂肪酶、淀粉酶及血浆容量的定量分析。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01

M Papp, G Folly, P E Németh

引用次数: 0

Effect of cholecystokinin octapeptide sulphate ester on brain monoamines in the rat. 缩胆素硫酸八肽酯对大鼠脑单胺的影响。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01

M Fekete, M Várszegi, T Kádár, B Penke, K Kovács, G Telegdy

引用次数: 0

The role of membrane processes in controlling skeletal muscle function. 膜突在控制骨骼肌功能中的作用。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01

L Kovács

引用次数: 0

Effects of ACTH and PGE2 on ovarian venous outflow, progesterone and oestradiol-17 beta secretion in the HCG primed bitch. ACTH和PGE2对HCG启动母狗卵巢静脉流出、孕酮和雌二醇-17分泌的影响。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01

E Horváth, B Varga, E Stark

引用次数: 0

Regulation of brain prostaglandins by sexual steroids. 性类固醇对脑前列腺素的调节。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01

A Gecse, A Ottlecz, G Telegdy

{"title":"Regulation of brain prostaglandins by sexual steroids.","authors":"A Gecse, A Ottlecz, G Telegdy","doi":"","DOIUrl":"","url":null,"abstract":"Hypothalamic PGF2 alpha content was determined by radioimmunoassay in rats. The male animals had significantly higher PGF/2 alpha level than the females. The hypothalamic PGF2alpha content increased following orchidectomy (GDX), while ovariectomy alone or combined with oestrone (100 microgram/kg or 1mg/kg i.m.) resulted in a significant i.m.) alone was ineffective. Testosterone (1 or 5 mg/kg i.m.) in GDX animals restored the hypothalamic PGF2 alpha content to the control level. The synthesis and breakdown of prostaglandins were also studied in the microsomal and cytosol fraction of brain homogenate. The PGD2 was the main product of the arachidonate cascade in rat brain microsomes. OVX increased the formation of PGD2 and diminished the biosynthesis of PGF2 alpha. Oestrone administration to OVX rats enhanced the formation of PGF2 alpha. Progesterone injection decreased the biosynthesis of PGF2 alpha and PGD2 alpha and PGD2 in OVX animals. Combined administration of progesterone and oestrone to OVX rats failed to restore the PGF2 alpha synthesis. In orchidectomized animals the arachidonate cascade was found to be depressed, further the synthesis of prostaglandins was normalized after testosterone substitution. The inactivation of 3H-PGF2 alpha by rat brain cytosol fraction was negligible.","PeriodicalId":7049,"journal":{"name":"Acta physiologica Academiae Scientiarum Hungaricae","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17849084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of acetylcholine on ion transport in the frog skeletal muscle. 乙酰胆碱对青蛙骨骼肌离子转运的影响。

Acta physiologica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01

L Kovács, G Szücs, I Török

{"title":"Effect of acetylcholine on ion transport in the frog skeletal muscle.","authors":"L Kovács, G Szücs, I Török","doi":"","DOIUrl":"","url":null,"abstract":"1. The effect of acetylcholine (ACh) on the ion transport of frog (Rana esculenta) sartorius muscles was studied. ACh was applied in bathing solution, Na influx and K efflux were measured using 24Na and 42K isotopes. 2. Na influx of sartorius muscles was increased by 1 mmol/1 ACh 2-10 fold depending on the experimental arrangement. The increase was greater if Na influx was measured at the beginning of ACh depolarization. During ACh treatment the Na influx took about the same time course as the depolarization recorded extracellularly. This type of recording approximately reflects the depolarization proceeding on the sartorius muscle fibres. 3. The presence of 31 nmol/l tetrodotoxin (TTX) did not modify the degree of increase of Na influx. 4. Rate coefficients for K efflux were increased 2-5 fold by ACh. The maximum rate coefficients were obtained in the first minute of ACh treatment. 5. Increase in K loss evolves also in the presence of 31 nmol/l TTX. The increase in rate coefficients was found to be about 30% less than without TTX in the first minute of ACh action. 6. The results indicate that in the presence of ACh the observed increase in Na influx and K efflux is brought about mainly by changes in Na and K conductance induced by ACh at the end-plates rather than by the action potentials accompanying ACh depolarization.","PeriodicalId":7049,"journal":{"name":"Acta physiologica Academiae Scientiarum Hungaricae","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18026827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0