Xavier León , Ana Gimenez , Julia de Juan , Camilo Rodríguez , Miquel Quer , Albert Pujol
{"title":"¿Está justificado hacer un screening a largo plazo para el cáncer de pulmón en los pacientes con un carcinoma de cabeza y cuello?","authors":"Xavier León , Ana Gimenez , Julia de Juan , Camilo Rodríguez , Miquel Quer , Albert Pujol","doi":"10.1016/j.otorri.2022.05.005","DOIUrl":"https://doi.org/10.1016/j.otorri.2022.05.005","url":null,"abstract":"<div><h3>Objective</h3><p>Patients with head and neck squamous cell carcinoma (HNSCC) have a higher risk of second lung neoplasms than the general population. The aim of the present study is to evaluate the long-term incidence of second lung malignancies after the diagnosis of a HNSCC and to consider the convenience of the screening for lung cancer in these patients.</p></div><div><h3>Material and methods</h3><p>We conducted a retrospective study performed on 4,954 patients with an index tumor located in the oral cavity, oropharynx, hypopharynx, or larynx during the period 1985-2017.</p></div><div><h3>Results</h3><p>During the follow-up period 469 patients (9.5%) presented a second pulmonary neoplasm. The incidence of second lung neoplasm was 1.26% per year and remained practically constant throughout the 25-year follow-up period analyzed. According to the results of a multivariate study, male patients, aged between 50 and 80 years, with a history of tobacco use, and with tumors located in the oropharynx or the supraglottis were those with the highest risk of second lung neoplasms.</p></div><div><h3>Conclusion</h3><p>Patients with a HNSCC index tumor have a high risk of second neoplasms located in the lung. In order to achieve an early diagnosis of these second neoplasms, it would be advisable to establish screening protocols based on the use of low-dose lung CT, which should be maintained indefinitely during the follow-up period.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49779241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative study on Saliva and Nasopharyngeal swabs and the outcome of RT-PCR test in patients with mild symptoms of SARS-CoV-2","authors":"Satvinder Singh Bakshi , V. Mangayarkarasi , Debabrata Dash , Soumyajit Das , Seepana Ramesh , Cheeranjeevi Jayam , Vinoth Kumar Kalidoss","doi":"10.1016/j.otorri.2022.12.001","DOIUrl":"https://doi.org/10.1016/j.otorri.2022.12.001","url":null,"abstract":"<div><h3>Aim</h3><p>A simple and reliable method for diagnosing COVID 19 infections is the needed. The role of saliva in the transmission of the infection has already been established.</p></div><div><h3>Method</h3><p>Saliva and nasopharyngeal swabs from patients suspected to have COVID 19 infections were taken simultaneously, and the results of the RT-PCR were compared.</p></div><div><h3>Result</h3><p>Total 405 samples were collected, of which 250 males and 155 females. In the 391 samples included for analysis, 370 (94.63%) samples were found to have concordance results, and 21 (5.37%) samples had discordant results.</p></div><div><h3>Conclusion</h3><p>The use of saliva to diagnose COVID 19 infection is reliable, and its use can be recommended.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49779260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Manifestaciones otológicas de la enfermedad relacionada con IgG4","authors":"Laura Baldizán Velasco , Carmelo Morales-Angulo","doi":"10.1016/j.otorri.2022.08.001","DOIUrl":"10.1016/j.otorri.2022.08.001","url":null,"abstract":"<div><p>IgG4-related disease (IgG4-RD) is a systemic autoimmune fibroinflammatory disease characterized by multiorgan infiltration of IgG4-positive plasma cells, fibrosis and vasculopathy that determine dysfunction of the affected organ. This review aims to characterize the otologic manifestations of the disease.</p><p>We have conducted a systematic review of the biomedical literature published describing cases of IgG4-RD with otologic manifestations. For the review, the bibliographic databases utilized were Pubmed, Web of Science and Scopus. We selected 48 cases from which we extracted several data collections.</p><p>About 52% of the patients were male between the ages of 19 and 79 years. Otologic findings were characterized by pseudotumoral lesions that most often caused a clinical presentation similar to otitis media with effusion, with cochlear involvement or sensorineural hearing loss (uni or bilateral). Less frequent presentations included auricular chondritis, eosinophilic otitis, or hypertrophic pachymeningitis. In 32 patients (67%) the otologic manifestation was the first symptom of the ER-IgG4.</p><p>Sixteen patients (33%) were treated with mastoidectomies as a result of delayed diagnosis and lack of knowledge about this entity. Two patients needed a cochlear implant.</p><p>Although the otologic manifestations of IgG4-RD are unusual, it is important for the otorhinolaryngologist to know the otologic manifestations of this entity as it can be the onset of the disease, in order to allow early diagnosis and adequate treatment, avoiding permanent sequelae.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49648708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evolución de la incidencia de las enfermedades infecciosas del área ORL en edad pediátrica durante la pandemia COVID-19","authors":"Lidia Torres-García , Raúl Mellidez Acosta , Antonio Cañada Martínez , Isabel Ibáñez Alcañiz , Agustín Alamar Velázquez , Miguel Armengot Carceller","doi":"10.1016/j.otorri.2022.07.005","DOIUrl":"https://doi.org/10.1016/j.otorri.2022.07.005","url":null,"abstract":"<div><h3>Introduction</h3><p>SARS COV-2 infection is an emerging disease that has become a global pandemic since the beginning of 2020. To reduce transmission, measures have been imposed by governments such as home confinement, the use of masks, social distancing or promotion of hand hygiene. The aim of this study is to determine if the measures adopted to reduce the COVID-19 pandemic have produced a decrease in the incidence of infectious diseases and their complications in the ENT area in our center.</p></div><div><h3>Material and methods</h3><p>A retrospective descriptive study was carried out in a tertiary hospital of patients aged between 0 and 15 years who required admission due to deep cervical infections, complications derived from acute otitis media (mastoiditis or facial paralysis) or complicated acute sinusitis.</p></div><div><h3>Results</h3><p>There is a notable decrease in the number of global admissions in the COVID period (9) compared to the average of the previous 5 years (20.1). Likewise, there are statistically significant differences in the number of admissions for cervical infections (<em>P</em> = .027) and complications derived from acute otitis media (<em>P</em> = .029).</p></div><div><h3>Discussion/conclusion</h3><p>A decrease in the number of admissions caused by complications of infections in the ENT area in paediatric patients has been observed after the start of the COVID-19 pandemic in our environment, this fact could be explained by a global decrease in the number of infections of the upper respiratory tract due to the hygienic measures taken by the COVID-19 pandemic.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49778563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mafalda Correia de Oliveira , Miguel Martins , Pedro Correia-Rodrigues
{"title":"Oropharyngeal and laryngeal manifestations of human monkeypox","authors":"Mafalda Correia de Oliveira , Miguel Martins , Pedro Correia-Rodrigues","doi":"10.1016/j.otorri.2022.07.003","DOIUrl":"https://doi.org/10.1016/j.otorri.2022.07.003","url":null,"abstract":"","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49778565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Holgado , Xavier León , Miquel Quer , Valle Camacho , Alejando Fernández
{"title":"Asociación entre el standarized uptake value (SUV) máximo y el control local en pacientes con carcinoma de orofaringe tratados con radioterapia","authors":"Anna Holgado , Xavier León , Miquel Quer , Valle Camacho , Alejando Fernández","doi":"10.1016/j.otorri.2022.05.004","DOIUrl":"https://doi.org/10.1016/j.otorri.2022.05.004","url":null,"abstract":"<div><h3>Objective</h3><p>To analyse the prognostic ability of the maximum standardised uptake value (SUV<sub>max</sub>) on local disease control in patients with oropharyngeal carcinoma treated with radiotherapy.</p></div><div><h3>Material and methods</h3><p>Retrospective study of 105 patients with oropharyngeal carcinomas treated with radiotherapy, including chemo- and bio-radiotherapy, and who had a PET-CT scan prior to the start of treatment.</p></div><div><h3>Result</h3><p>Patients with a SUV<sub>max</sub> value higher than 17.2 at the primary tumour site had a significantly higher risk of local recurrence. The 5-year local recurrence-free survival for patients with SUV<sub>max</sub> less than or equal to 17.2 (<em>n</em> <!-->=<!--> <!-->71) was 86.5% (95% CI: 78.2–94.7%), and for patients with SUV<sub>max</sub> greater than 17.2 (<em>n</em> <!-->=<!--> <!-->34) it was 55.8% (95% CI: 36.0–75.6%) (<em>P</em>=.0001). This difference in local control was maintained regardless of patients’ HPV status. Specific survival was similarly lower for patients with a SUV greater than 17.2. The 5-year specific survival for patients with SUV<sub>max</sub> greater than 17.2 was 39.5% (95% CI: 20.6–58.3%), significantly shorter than that of patients with SUV<sub>max</sub> equal to or less than 17.2, which was 77.3% (95% CI: 66.9–87.6%) (<em>P</em>=.0001).</p></div><div><h3>Conclusions</h3><p>Patients with oropharyngeal carcinomas treated with radiotherapy with a SUV<sub>max</sub> greater than 17.2 at the level of the primary tumour site had a significantly higher risk of local recurrence.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49778566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Variación de los parámetros acústicos: f0, Jitter, Shimmer y Alpha ratio en relación con distintos niveles de ruido de fondo","authors":"María José Marsano-Cornejo , Ángel Roco-Videla","doi":"10.1016/j.otorri.2022.06.003","DOIUrl":"https://doi.org/10.1016/j.otorri.2022.06.003","url":null,"abstract":"<div><h3>Background and objectives</h3><p>Research involving acoustic analysis does not always consider the level of background noise in the room where the recording process is going to be carried out, or if they do, the maximum value of background noise used varies from author to author. The objective of this research is to establish if the parameters: f<sub>0</sub>, Jitter, Shimmer and Alpha ratio vary in relation to different levels of background noise in the room where the recording process is carried out and to establish a maximum value of this.</p></div><div><h3>Materials and methods</h3><p>The Praat program was used to get the average value of the parameters: f<sub>0</sub>, Jitter, Shimmer and Alpha ratio from a voice sample of 33 subjects inside an audiometric booth whose background noise level was 28.1<!--> <!-->dB(A). A statistical comparison was made between the average value of each parameter as the background noise increased in relation to the average values obtained with the baseline background noise of the cabin for each parameter.</p></div><div><h3>Results</h3><p>The f<sub>0</sub> and Alpha ratio parameters show reliable values up to a background noise level of 47.7<!--> <!-->dB(A), while the Jitter and Shimmer parameters do so up to a background noise level of 43.8<!--> <!-->dB(A).</p></div><div><h3>Conclusions</h3><p>Considering that the acoustic parameters are all obtained from the same recording, we can point out that the recommended maximum background noise level in the room where the recordings are made should not exceed 43.8<!--> <!-->dB(A).</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49778564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maurizio Barbara , Saad Elzayat , Ashraf Lotfy , Luigi Sabino , Giorgio Bandiera , Hossam S. Elsherif , Maiada Youssef , Ayman Fouad , Khaled Nasr , Luigi Volpini , Haitham H. Elfarargy
{"title":"Invasive fungal rhinosinusitis associated with COVID-19: Course changes and prognosis predictors","authors":"Maurizio Barbara , Saad Elzayat , Ashraf Lotfy , Luigi Sabino , Giorgio Bandiera , Hossam S. Elsherif , Maiada Youssef , Ayman Fouad , Khaled Nasr , Luigi Volpini , Haitham H. Elfarargy","doi":"10.1016/j.otorri.2022.09.003","DOIUrl":"https://doi.org/10.1016/j.otorri.2022.09.003","url":null,"abstract":"<div><h3>Background</h3><p>This study aimed to analyze the behavior of acute invasive fungal rhinosinusitis (AIFRS) associated with COVID-19 infection as there has been an increase in the rate of AIFRS cases in the last two years, and many reports connected this rising with the COVID-19 infection. We studied most factors that may impact the prognosis as a trial to find the most affecting factors to improve the outcomes.</p></div><div><h3>Methods</h3><p>It was a retrospective observational study that included cases from four tertiary referral institutions between November 2020 to February 2022. We included sixty-six patients who suffered from AIFRS associated with confirmed COVID-19. We observed the prognosis of all included patients with a six-month follow-up. We correlated the prognosis with many factors, such as demographic data, medical conditions, blood investigations, the features of fungal infections, and management.</p></div><div><h3>Results</h3><p>Forty-two patients (64%) survived after the AIFRS associated with COVID-19, and twenty-two patients (36%) died. High doses of corticosteroids with prolonged use were the main factors that affected the behavior of the AIFRS associated with COVID-19. HbA1c was a good predictor of the prognosis; a level less than 9.35% may indicate survival with 87.5% sensitivity.</p></div><div><h3>Conclusions</h3><p><span>According to this multi-center study, the mortality of the AIFRS associated with COVID-19 was high. The behavior was affected by glycemic control<span><span>, the type of fungal species, and the type of antifungal therapy<span>. Early surgical debridement, a combination of </span></span>Amphotericin B with </span></span>Voriconazole<span>, and anticoagulants helped improve the prognosis.</span></p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49778603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Catarina Carvalho, Ana S. Marinho, Joana Barbosa-Sequeira, Mário R. Correia, José Banquart-Leitão, Fátima Carvalho
{"title":"Quality of life after otoplasty for prominent ears in children","authors":"Catarina Carvalho, Ana S. Marinho, Joana Barbosa-Sequeira, Mário R. Correia, José Banquart-Leitão, Fátima Carvalho","doi":"10.1016/j.otorri.2022.07.004","DOIUrl":"https://doi.org/10.1016/j.otorri.2022.07.004","url":null,"abstract":"<div><h3>Aim</h3><p><span>Prominent ears are a common congenital malformation and are associated with low self-esteem, social isolation and diminished school performance. Our goal was to evaluate the influence of </span>otoplasty<span> on children’s quality of life (QoL).</span></p></div><div><h3>Material and methods</h3><p>Patients submitted to otoplasty from 2016 to 2018 were summoned for a reevaluation. Seventy patients and respective caregivers agreed to participate. Surgical, demographic and clinical data were reviewed from electronic registries.</p></div><div><h3>Two sets of inquiries were performed</h3><p>Pediatric Quality of Life Inventory 4.0 (for parent and child) and an adaptation of the Glasgow Children Benefit Inventory (GCBI-b). Fifteen patients were excluded for incomplete inquiries.</p></div><div><h3>Results</h3><p>Fifty-five patients were included, 70.9% were males. Median age at surgery was 7.7 ± 3.3 years. Aesthetic dissatisfaction was the main previous negative experience. Median self-report quality of life was 85.6% and parent-report was 86.9%. Median GCBI-b was +20.5, indicating an improvement in patients’ QoL. Bullying and high parental expectations for life change post-surgery were predictive of higher GCBI-b scores (p < 0.05). Ninety-six percent of parents would recommend surgery to other children.</p></div><div><h3>Conclusions</h3><p>Otoplasty is a valid treatment option for prominent ears in children,improving not only aesthetics but also health-related QoL.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49778562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}