Acta otorrinolaringologica espanola最新文献_第9页

Management of orbital complications of acute rhinosinusitis: A 13-year experience 急性鼻窦炎眼眶并发症的处理：13年的经验

IF 1.1

Acta otorrinolaringologica espanola Pub Date : 2025-09-01 Epub Date: 2025-09-18 DOI: 10.1016/j.otorri.2025.512262

Monica Rueda Vega , M Montserrat Asensi Diaz , María C Scola Torres , Carolina López Granados , Mónica Hernando , Juan Antonio Pasamontes

{"title":"Management of orbital complications of acute rhinosinusitis: A 13-year experience","authors":"Monica Rueda Vega , M Montserrat Asensi Diaz , María C Scola Torres , Carolina López Granados , Mónica Hernando , Juan Antonio Pasamontes","doi":"10.1016/j.otorri.2025.512262","DOIUrl":"10.1016/j.otorri.2025.512262","url":null,"abstract":"<div><h3>Introduction</h3><div>After the development of antibiotics and early diagnostic methods, the complications of acute rhinosinusitis (ARS) have reduced in recent years. However, in clinical practice, we still observe both orbital and intracranial complications.</div><div>The aim of this study is to describe a series of patients with complications of ARS and to define what clinical and radiological characteristics may indicate the need of surgical treatment.</div></div><div><h3>Materials</h3><div>Retrospective observational study of patients diagnosed with orbital complications secondary to ARS who were hospitalized at a tertiary hospital between 2010 and 2023. Demographic, clinical, radiological, microbiological data, therapeutic strategy and hospitalization time were studied.</div></div><div><h3>Results</h3><div>Fifty-six patients were included (59% male), with a mean age of 11.5 years (37 under 18 years old). The most frequent symptoms were eyelid edema (98%) and erythema (89%), proptosis (46%) and fever (50%). According to Chandler’s classification, the most frequent complications were subperiosteal abscesses (46%) and orbital cellulitis (23%). There were six cases of orbital abscesses and one cavernous sinus thrombosis. The most frequently used antibiotic was amoxicillin + clavulanic acid (54%). Surgical intervention was necessary in 26 patients (46%).</div></div><div><h3>Conclusion</h3><div>Orbital complications of ARS are rare, but they can have potentially vision-threatening and life-threatening complications. Therefore, it is essential to consider them in the differential diagnosis, and in case of suspicion, initiate antibiotic treatment as soon as possible, with or without surgical drainage. Endoscopic surgery is the preferred approach, but it may be necessary to combine it with external drainage, especially in lateral locations or on the orbital roof.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 5","pages":"Article 512262"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring DIAPH1 gene mutations in patients with sensorineural hearing loss of unknown etiology in Northern Spain 探索在西班牙北部不明病因感音神经性听力损失患者中膜片基因突变

IF 1.1

Acta otorrinolaringologica espanola Pub Date : 2025-09-01 Epub Date: 2025-09-18 DOI: 10.1016/j.otorri.2025.512269

Rocío González-Aguado , Aida Veiga-Alonso , Esther Onecha-De La Fuente , Carmelo Morales-Angulo

{"title":"Exploring DIAPH1 gene mutations in patients with sensorineural hearing loss of unknown etiology in Northern Spain","authors":"Rocío González-Aguado , Aida Veiga-Alonso , Esther Onecha-De La Fuente , Carmelo Morales-Angulo","doi":"10.1016/j.otorri.2025.512269","DOIUrl":"10.1016/j.otorri.2025.512269","url":null,"abstract":"<div><h3>Objective</h3><div>To determine the prevalence of variants in the DIAPH1 gene among patients with bilateral sensorineural hearing loss of unknown etiology in northern Spain and to characterize the associated phenotype. As a secondary objective, this study aims to improve genetic counseling by linking genotype to phenotype through clinical characterization of variant carriers.</div></div><div><h3>Patients and methods</h3><div>A six-year observational descriptive study was conducted at a tertiary referral center. Patients with bilateral sensorineural hearing loss of unknown origin were evaluated using DNA sequencing through next-generation sequencing. A gene panel was utilized to identify pathogenic or likely pathogenic variants in the DIAPH1 gene.</div></div><div><h3>Results</h3><div>Among 385 patients with SNHL, four (1%) harbored DIAPH1 variants. Two patients (0.5%) had pathogenic or likely pathogenic variants associated with macrothrombocytopenia and neutropenia (c.3586dupA, c.3575-3C>G), exhibiting early-onset, progressive bilateral SNHL, and vestibular abnormalities. One received a cochlear implant with good outcomes. Conclusions: Pathogenic variants in the DIAPH1 gene are rare among patients with bilateral sensorineural hearing loss of unknown etiology in northern Spain. These variants lead to bilateral SNHL with autosomal dominant inheritance. In our study, we identified two novel pathogenic DIAPH1 variants associated with macrothrombocytopenia, and also presenting neutropenia and vestibular involvement.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 5","pages":"Article 512269"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Otorhinolaryngological manifestations in patients with eosinophilic granulomatosis with polyangiitis in a single university center 单一大学中心嗜酸性肉芽肿病合并多血管炎患者的耳鼻喉科表现

IF 1.1

Acta otorrinolaringologica espanola Pub Date : 2025-09-01 Epub Date: 2025-09-18 DOI: 10.1016/j.otorri.2025.512263

Julia Fernández-Enseñat , Fabricio Benavides-Villanueva , Andrea Martínez-Camerano , Vanesa Calvo-Rio , Ricardo Blanco , Carmelo Morales-Angulo

{"title":"Otorhinolaryngological manifestations in patients with eosinophilic granulomatosis with polyangiitis in a single university center","authors":"Julia Fernández-Enseñat , Fabricio Benavides-Villanueva , Andrea Martínez-Camerano , Vanesa Calvo-Rio , Ricardo Blanco , Carmelo Morales-Angulo","doi":"10.1016/j.otorri.2025.512263","DOIUrl":"10.1016/j.otorri.2025.512263","url":null,"abstract":"<div><h3>Objectives</h3><div>Eosinophilic granulomatosis with polyangiitis (EGPA) is an ANCA-associated vasculitis affecting multiple systems, with common ear, nose and throat (ENT) manifestations. This study aimed to evaluate the most frequent ENT manifestations in EGPA patients and the relationship between nasal polyps and other clinical findings such as ANCA tests and eosinophilia.</div></div><div><h3>Materials and methods</h3><div>A retrospective observational study was conducted on EGPA patients diagnosed between 2000 and 2024 at a tertiary hospital using the 2022 ACR/EULAR criteria. Head and neck examinations, including audiometry, and their imaging and histopathological studies were reviewed. Patients were classified based on the presence or absence of nasal polyps, and the relationship between ANCA positivity and eosinophilia was assessed.</div></div><div><h3>Results</h3><div>Of 173 patients with ANCA vasculitis, 22 met EGPA criteria, with a prevalence of 3.6 per 100,000 in Cantabria. Head and neck manifestations were observed in 90.5% of patients (19/21). Sinonasal involvement was the most frequent (82%), with otological manifestations in 31.8% (7/21). Nasal polyps were the most common manifestation (7/21). Head and neck biopsies were performed in 7 cases (32%), which showed no evidence of vasculitis. There was no statistically significant association between nasal polyps, ANCA positivity, and eosinophilia.</div></div><div><h3>Conclusions</h3><div>Sinonasal involvement is prevalent in EGPA, often presenting as chronic rhinitis or rhinosinusitis with or without polyps. Otological issues, such as eustachian tube dysfunction and sensorineural hearing loss, are also common. No laryngeal, oral, or salivary gland lesions were observed. There was no significant correlation between the presence of polyps and ANCA positivity or eosinophilia.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 5","pages":"Article 512263"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nódulos en bambú de las cuerdas vocales: un reto clínico poco común 声带竹结节：罕见的临床挑战

IF 1.1

Acta otorrinolaringologica espanola Pub Date : 2025-09-01 Epub Date: 2025-07-18 DOI: 10.1016/j.otorri.2025.512266

María San Millán-González , Michael Bauer , Ana Fernández-Rodríguez , José Antonio Cámara-Arnaz

引用次数: 0

Adenopatía retrofaríngea en carcinoma sobre divertículo de Zenker Zenker憩室癌中的后咽部腺病

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Acta otorrinolaringologica espanola Pub Date : 2025-09-01 Epub Date: 2025-07-17 DOI: 10.1016/j.otorri.2025.512267

Beatriz Pallarés Martí, Juan José Díaz Argüello, Yolanda Escamilla Carpintero

引用次数: 0

Comparison of the EPOS 2020 and POLINA 2.0 guidelines for indicating biologic treatment in adults with chronic rhinosinusitis and nasal polyps epos2020和POLINA 2.0指南对成人慢性鼻窦炎和鼻息肉生物治疗的比较

IF 0.9

Acta otorrinolaringologica espanola Pub Date : 2025-07-01 Epub Date: 2025-07-28 DOI: 10.1016/j.otorri.2025.512224

Mireia Golet , Núria Padullés-Zamora , Alejandro Portillo , José María Caballero , Mariana Muñoz Esquerre , Joaquín Sastre , Isam Alobid , Xavier González-Compta

{"title":"Comparison of the EPOS 2020 and POLINA 2.0 guidelines for indicating biologic treatment in adults with chronic rhinosinusitis and nasal polyps","authors":"Mireia Golet , Núria Padullés-Zamora , Alejandro Portillo , José María Caballero , Mariana Muñoz Esquerre , Joaquín Sastre , Isam Alobid , Xavier González-Compta","doi":"10.1016/j.otorri.2025.512224","DOIUrl":"10.1016/j.otorri.2025.512224","url":null,"abstract":"<div><h3>Objective</h3><div>To analyze the volume of patients with chronic rhinosinusitis with nasal polyps (CRSwNP) to whom biologics would be prescribed based on the European and Spanish clinical practice guidelines, and to evaluate the impact that an increase of 1 required prior surgery (from 1 to 2) may have on the number of indications.</div></div><div><h3>Methods</h3><div>Cross-sectional analysis evaluating the application of the European Position Paper on CRSwNP Guidelines (EPOS 2020) and the Spanish Consensus on the Management of CRSwNP Guidelines (POLINA 2.0) on an on-going prospective cohort study of consecutive patients with severe CRSwNP in a tertiary hospital.</div></div><div><h3>Results</h3><div>For a total of 103 patients with severe CRSwNP, 57.3% met EPOS 2020 criteria for biological treatment, whereas only 32% met POLINA 2.0 criteria. However, if the number of surgeries required to prescribe a biological therapy is increased to 2, only 31.1% of the patients would have indication of biological treatment, in any of the two guidelines.</div></div><div><h3>Conclusions</h3><div>The differences among the POLINA 2.0 and the EPOS 2020 guidelines appear to have an impact in the proportion of patients eligible for biological therapies, with the former being stricter. Increasing the number of prior surgeries required, reduces the proportion of patients eligible for monoclonal antibodies prescription.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512224"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impacto de la rinosinusitis crónica con pólipos nasales en la disfunción de la trompa de Eustaquio 慢性鼻窦炎与鼻息肉对尤斯特流功能障碍的影响

IF 0.9

Acta otorrinolaringologica espanola Pub Date : 2025-07-01 Epub Date: 2025-07-22 DOI: 10.1016/j.otorri.2025.512235

Francisco Javier García-Callejo , Miguel Juantegui Azpilicueta , María Díaz Ferrer , Pablo Tiziano Guastella Almeida , John Deiver Cardona Henao

{"title":"Impacto de la rinosinusitis crónica con pólipos nasales en la disfunción de la trompa de Eustaquio","authors":"Francisco Javier García-Callejo , Miguel Juantegui Azpilicueta , María Díaz Ferrer , Pablo Tiziano Guastella Almeida , John Deiver Cardona Henao","doi":"10.1016/j.otorri.2025.512235","DOIUrl":"10.1016/j.otorri.2025.512235","url":null,"abstract":"<div><h3>Introduction</h3><div>Adequate nasal patency has been classically considered a crucial factor in middle ear ventilation. We valued the influence of nasosinusal polyposis on Eustachian tube function.</div></div><div><h3>Material and methods</h3><div>A prospective follow-up with all cases of chronic rhinosinusitis with nasal polyps assisted between January 2019 and October 2024 was carried out. Their endoscopic, radiological and clinical characteristics were noted, as well as the presence of a type 2 inflammation context and the incidence of middle ear pathology. Polypoid involvement and tubal dysfunction were studied using several scores: Lildholdt's scale, Lund-Mackay nasal polyp grading, Lund-Kennedy endoscopic scoring system, SNOT-22 and Eustachian Tube Dysfunction Questionnaire-7 score.</div></div><div><h3>Results</h3><div>Information was collected from 155 patients, with an incidence of 15.1 cases/100,000 inhabitants. A percentage of 70.9 showed a type 2 inflammation profile. This group showed a higher average of cases with acute otitis media and effusion (18.1 vs. 4.4%; p<0.001), tympanometric alterations (12.7 vs. 4.4%; p<0.01), conductive hearing loss (17.2 vs. 4.4%; p<0.001) and needing for transtympanic drains (9.1 vs. 2.2%; p<0.01) than the group without an eosinophilic profile or elevated IgE. The Eustachian Tube Dysfunction Questionnaire-7 score correlated well with the SNOT-22 and Lund-Kennedy scales.</div></div><div><h3>Conclusions</h3><div>Regression analysis revealed that a type 2 inflammation profile might play a more important role in tubal patency than nasal obstruction. Polyposis may alter Eustachian tube function, but more likely due to its inflammatory-allergic etiopathogenesis than to its obstructive nature.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512235"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anatomical variations of sphenoid sinus on cone beam computed tomography 锥束计算机体层摄影在蝶窦解剖上的变化

IF 0.9

Acta otorrinolaringologica espanola Pub Date : 2025-07-01 Epub Date: 2025-07-28 DOI: 10.1016/j.otorri.2025.512229

Patrícia Fernandes Lopes , Tatiana Carvalho , Miguel Furtado

{"title":"Anatomical variations of sphenoid sinus on cone beam computed tomography","authors":"Patrícia Fernandes Lopes , Tatiana Carvalho , Miguel Furtado","doi":"10.1016/j.otorri.2025.512229","DOIUrl":"10.1016/j.otorri.2025.512229","url":null,"abstract":"<div><h3>Introduction</h3><div>The surgical approach to the sphenoid sinus (SS) is one of the most challenging aspects of endoscopic surgery due to its proximity to critical structures. To minimize risks, computed tomography (CT) aids in navigational guidance. Although cone beam computed tomography (CBCT) has lower contrast resolution, it offers improved precision, reduced radiation exposure, and faster imaging, making it a viability as a preoperative tool.</div></div><div><h3>Methods</h3><div>We randomly selected 75 patients from 707 who underwent CBCT between January and December 2023. Two observers evaluated SS anatomy with consensus. Statistical analyses were conducted using Excel® and Jamovi®.</div></div><div><h3>Results</h3><div>Anatomical variations were documented, with prevalence rates as follows: sphenoethmoidal cell (15%); optic nerve (ON) protrusion (21%) and dehiscence (4%); internal carotid artery (ICA) protrusion (31%) and dehiscence (0%); vidian canal (VC) protrusion (39%) and dehiscence (6%); foramen rotundum (FR) protrusion (23%) and dehiscence (5%); anterior clinoid process (ACP) pneumatization (20%); pterygoid process (PP) pneumatization (33%); conchal (1%), presellar (7%), sellar (36%) and postsellar type (56%) SS; and intersphenoidal septum (47%). Statistically significant correlations were observed between ACP pneumatization and ON protrusion (<em>p</em> < 0.001) and dehiscence (<em>p</em> = 0.018), and ICA protrusion (<em>p</em> = 0.001). PP pneumatization was significantly correlated with VC protrusion (<em>p</em> < 0.001) and dehiscence (<em>p</em> = 0.011), and foramen rotundum protrusion (<em>p</em> < 0.001).</div></div><div><h3>Discussion/Conclusion</h3><div>Our CBCT findings largely aligned with CT data in existing literature. Due to its faster acquisition and lower radiation exposure, CBCT shows potential as a preoperative evaluation method for assessing the SS.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512229"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Características acústicas de la voz de los niños usuarios de implante coclear 人工耳蜗使用者儿童声音的声学特征

IF 0.9

Acta otorrinolaringologica espanola Pub Date : 2025-07-01 Epub Date: 2025-04-05 DOI: 10.1016/j.otorri.2025.512238

Faustino Núñez-Batalla , Ainoa Álvarez , Isabel Sandoval , Paula Sánchez , Estefania Díaz-Fresno , Jorge Javier Ramírez , Maite Guntín , Justo Gómez , Jose Luis Llorente , Verónica Suárez-Martínez

{"title":"Características acústicas de la voz de los niños usuarios de implante coclear","authors":"Faustino Núñez-Batalla , Ainoa Álvarez , Isabel Sandoval , Paula Sánchez , Estefania Díaz-Fresno , Jorge Javier Ramírez , Maite Guntín , Justo Gómez , Jose Luis Llorente , Verónica Suárez-Martínez","doi":"10.1016/j.otorri.2025.512238","DOIUrl":"10.1016/j.otorri.2025.512238","url":null,"abstract":"<div><h3>Introduction</h3><div>Congenital profound bilateral hearing loss prevents the correct development of speech and voice. This study assesses certain acoustic parameters of the voice in order to determine their normality in the implanted population.</div></div><div><h3>Method</h3><div>Two population groups were studied. A control group consisting of 42 healthy pediatric patients, 22 boys and 20 girls, and a group of 22 pediatric patients, 11 boys and 11 girls with congenital profound hearing loss implanted bilaterally.</div><div>The variables median pitch, CPPS, <em>jitter</em> rap and <em>shimmer</em> apq5 were evaluated in an isolated phonation exercise and another in connected speech for the phoneme /a/ with the PRAAT program. Student's t-test and Wilcoxcon tests were applied.</div></div><div><h3>Results</h3><div>Significant intergroup differences were obtained for all variables in the vowel extracted from connected speech, but not in the sustained vowel. The hearing-impaired population showed some significant differences in the intra-group analysis. The experimental group showed better results in the vocal quality parameters, particularly jitter, shimmer and CPPS showed statistically significant differences.</div></div><div><h3>Conclusion</h3><div>Early bilateral implantation allows the cochlear implant user to approximate his acoustic values to normative values in terms of pitch, stability, quality and articulatory precision.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512238"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estratificación de la severidad de la sialoadenitis obstructiva crónica en función de su impacto en la calidad de vida 按对生活质量的影响对慢性阻塞性脊柱炎严重程度进行分层

IF 0.9

Acta otorrinolaringologica espanola Pub Date : 2025-07-01 Epub Date: 2025-06-25 DOI: 10.1016/j.otorri.2025.512223

William Aragonés Sanzen-Baker , José Miguel Villacampa Aubá , Ignacio Alcalá Rueda , Jessica Mireya Santillán Coello , Gonzalo Díaz Tapia , Carlos Cenjor Español , Álvaro Sánchez Barrueco

{"title":"Estratificación de la severidad de la sialoadenitis obstructiva crónica en función de su impacto en la calidad de vida","authors":"William Aragonés Sanzen-Baker , José Miguel Villacampa Aubá , Ignacio Alcalá Rueda , Jessica Mireya Santillán Coello , Gonzalo Díaz Tapia , Carlos Cenjor Español , Álvaro Sánchez Barrueco","doi":"10.1016/j.otorri.2025.512223","DOIUrl":"10.1016/j.otorri.2025.512223","url":null,"abstract":"<div><h3>Introduction</h3><div>Chronic Obstructive Sialadenitis (COS) is a debilitating condition characterized by recurrent inflammation of the salivary glands due to excretory obstruction, significantly impacting patients’ quality of life (QoL). The COS Quality of Life Questionnaire (COSQ) has been validated to evaluate QoL in affected patients and to monitor changes post-treatment.</div></div><div><h3>Materials and methods</h3><div>This study included two patient groups with COS-affected glands. The first group of 342 patients completed the COSQ before minimally invasive surgery, while the second group of 215 patients completed both the COSQ and a Visual Analog Scale (VAS). Scores were analyzed and stratified into four severity categories: mild, moderate, severe, and very severe, based on COSQ outcomes.</div></div><div><h3>Results</h3><div>COSQ scores were distributed as follows: mild (12.87%), moderate (37.13%), severe (34.5%), and very severe (15.21%). A significant correlation was observed between COSQ and VAS scores, particularly in the moderate and severe categories. Stratification allowed for identification of patients with severe symptoms, aiding in tailored management.</div></div><div><h3>Conclusion</h3><div>The COSQ effectively assesses QoL in COS patients and aids in stratifying severity. This stratification can guide clinicians in developing personalized treatment strategies, monitoring disease progression, and evaluating treatment outcomes.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512223"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0