Acta otorrinolaringologica espanola最新文献

{"title":"Impacto de la rinosinusitis crónica con pólipos nasales en la disfunción de la trompa de Eustaquio","authors":"Francisco Javier García-Callejo ,&nbsp;Miguel Juantegui Azpilicueta ,&nbsp;María Díaz Ferrer ,&nbsp;Pablo Tiziano Guastella Almeida ,&nbsp;John Deiver Cardona Henao","doi":"10.1016/j.otorri.2025.512235","DOIUrl":"10.1016/j.otorri.2025.512235","url":null,"abstract":"<div><h3>Introduction</h3><div>Adequate nasal patency has been classically considered a crucial factor in middle ear ventilation. We valued the influence of nasosinusal polyposis on Eustachian tube function.</div></div><div><h3>Material and methods</h3><div>A prospective follow-up with all cases of chronic rhinosinusitis with nasal polyps assisted between January 2019 and October 2024 was carried out. Their endoscopic, radiological and clinical characteristics were noted, as well as the presence of a type 2 inflammation context and the incidence of middle ear pathology. Polypoid involvement and tubal dysfunction were studied using several scores: Lildholdt's scale, Lund-Mackay nasal polyp grading, Lund-Kennedy endoscopic scoring system, SNOT-22 and Eustachian Tube Dysfunction Questionnaire-7 score.</div></div><div><h3>Results</h3><div>Information was collected from 155 patients, with an incidence of 15.1 cases/100,000 inhabitants. A percentage of 70.9 showed a type 2 inflammation profile. This group showed a higher average of cases with acute otitis media and effusion (18.1 vs. 4.4%; p<!--> <!-->&lt;<!--> <!-->0.001), tympanometric alterations (12.7 vs. 4.4%; p<!--> <!-->&lt;<!--> <!-->0.01), conductive hearing loss (17.2 vs. 4.4%; p<!--> <!-->&lt;<!--> <!-->0.001) and needing for transtympanic drains (9.1 vs. 2.2%; p<!--> <!-->&lt;<!--> <!-->0.01) than the group without an eosinophilic profile or elevated IgE. The Eustachian Tube Dysfunction Questionnaire-7 score correlated well with the SNOT-22 and Lund-Kennedy scales.</div></div><div><h3>Conclusions</h3><div>Regression analysis revealed that a type 2 inflammation profile might play a more important role in tubal patency than nasal obstruction. Polyposis may alter Eustachian tube function, but more likely due to its inflammatory-allergic etiopathogenesis than to its obstructive nature.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512235"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the EPOS 2020 and POLINA 2.0 guidelines for indicating biologic treatment in adults with chronic rhinosinusitis and nasal polyps","authors":"Mireia Golet ,&nbsp;Núria Padullés-Zamora ,&nbsp;Alejandro Portillo ,&nbsp;José María Caballero ,&nbsp;Mariana Muñoz Esquerre ,&nbsp;Joaquín Sastre ,&nbsp;Isam Alobid ,&nbsp;Xavier González-Compta","doi":"10.1016/j.otorri.2025.512224","DOIUrl":"10.1016/j.otorri.2025.512224","url":null,"abstract":"<div><h3>Objective</h3><div>To analyze the volume of patients with chronic rhinosinusitis with nasal polyps (CRSwNP) to whom biologics would be prescribed based on the European and Spanish clinical practice guidelines, and to evaluate the impact that an increase of 1 required prior surgery (from 1 to 2) may have on the number of indications.</div></div><div><h3>Methods</h3><div>Cross-sectional analysis evaluating the application of the European Position Paper on CRSwNP Guidelines (EPOS 2020) and the Spanish Consensus on the Management of CRSwNP Guidelines (POLINA 2.0) on an on-going prospective cohort study of consecutive patients with severe CRSwNP in a tertiary hospital.</div></div><div><h3>Results</h3><div>For a total of 103 patients with severe CRSwNP, 57.3% met EPOS 2020 criteria for biological treatment, whereas only 32% met POLINA 2.0 criteria. However, if the number of surgeries required to prescribe a biological therapy is increased to 2, only 31.1% of the patients would have indication of biological treatment, in any of the two guidelines.</div></div><div><h3>Conclusions</h3><div>The differences among the POLINA 2.0 and the EPOS 2020 guidelines appear to have an impact in the proportion of patients eligible for biological therapies, with the former being stricter. Increasing the number of prior surgeries required, reduces the proportion of patients eligible for monoclonal antibodies prescription.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512224"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomical variations of sphenoid sinus on cone beam computed tomography","authors":"Patrícia Fernandes Lopes ,&nbsp;Tatiana Carvalho ,&nbsp;Miguel Furtado","doi":"10.1016/j.otorri.2025.512229","DOIUrl":"10.1016/j.otorri.2025.512229","url":null,"abstract":"<div><h3>Introduction</h3><div>The surgical approach to the sphenoid sinus (SS) is one of the most challenging aspects of endoscopic surgery due to its proximity to critical structures. To minimize risks, computed tomography (CT) aids in navigational guidance. Although cone beam computed tomography (CBCT) has lower contrast resolution, it offers improved precision, reduced radiation exposure, and faster imaging, making it a viability as a preoperative tool.</div></div><div><h3>Methods</h3><div>We randomly selected 75 patients from 707 who underwent CBCT between January and December 2023. Two observers evaluated SS anatomy with consensus. Statistical analyses were conducted using Excel® and Jamovi®.</div></div><div><h3>Results</h3><div>Anatomical variations were documented, with prevalence rates as follows: sphenoethmoidal cell (15%); optic nerve (ON) protrusion (21%) and dehiscence (4%); internal carotid artery (ICA) protrusion (31%) and dehiscence (0%); vidian canal (VC) protrusion (39%) and dehiscence (6%); foramen rotundum (FR) protrusion (23%) and dehiscence (5%); anterior clinoid process (ACP) pneumatization (20%); pterygoid process (PP) pneumatization (33%); conchal (1%), presellar (7%), sellar (36%) and postsellar type (56%) SS; and intersphenoidal septum (47%). Statistically significant correlations were observed between ACP pneumatization and ON protrusion (<em>p</em> &lt; 0.001) and dehiscence (<em>p</em> = 0.018), and ICA protrusion (<em>p</em> = 0.001). PP pneumatization was significantly correlated with VC protrusion (<em>p</em> &lt; 0.001) and dehiscence (<em>p</em> = 0.011), and foramen rotundum protrusion (<em>p</em> &lt; 0.001).</div></div><div><h3>Discussion/Conclusion</h3><div>Our CBCT findings largely aligned with CT data in existing literature. Due to its faster acquisition and lower radiation exposure, CBCT shows potential as a preoperative evaluation method for assessing the SS.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512229"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A look at DFNB16 markers and their application in the genetic study of hearing loss in Iranian deaf families","authors":"Reihane Fazeli-Jezei ,&nbsp;Elham Davoudi-Dehaghani","doi":"10.1016/j.otorri.2025.512230","DOIUrl":"10.1016/j.otorri.2025.512230","url":null,"abstract":"<div><h3>Introduction</h3><div>The study of the gene encoding stereocilin (<em>STRC</em>) is complicated by the presence of a pseudogene (<em>STRCP1</em>) with over 98.8% similarity. We analysed the linkage between hearing loss and the DFNB16 locus in consanguineous Iranian deaf families.</div></div><div><h3>Materials and methods</h3><div>A review of previous studies on the DFNB16 locus was conducted to find the smallest regions linked to the <em>STRC</em> gene with no reported crossing-overs, as well as an investigation of short tandem repeat (STR) and single nucleotide polymorphism (SNP) markers of the DFNB16 locus using the UCSC, NCBI, and Iranome databases. A total of 36 consanguineous families with at least two individuals affected by autosomal recessive non-syndromic hearing loss (ARNSHL) were selected for the study. Autozygosity mapping was performed using tag SNP markers linked to the DFNB16 locus.</div></div><div><h3>Results</h3><div>The investigation showed that SNPs are more appropriate for linkage studies in these families than STR markers. In this study, 12 distinct haplotypes were identified, with frequencies ranging from 3.1% to 21.8%. Based on the haplotype analysis results and the autozygosity mapping, no linkage was found in any families analysed.</div></div><div><h3>Discussion</h3><div>In genetic studies of deafness in multi-affected consanguineous families, preliminary screening by autozygosity mapping can be helpful, especially for complicated genes like <em>STRC</em>. If the distance between STRs and the gene under study is significant, SNPs can provide a more effective solution. This study can potentially help to develop a more cost-effective method for genetic testing of <em>STRC</em>-related deafness.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512230"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Características acústicas de la voz de los niños usuarios de implante coclear","authors":"Faustino Núñez-Batalla ,&nbsp;Ainoa Álvarez ,&nbsp;Isabel Sandoval ,&nbsp;Paula Sánchez ,&nbsp;Estefania Díaz-Fresno ,&nbsp;Jorge Javier Ramírez ,&nbsp;Maite Guntín ,&nbsp;Justo Gómez ,&nbsp;Jose Luis Llorente ,&nbsp;Verónica Suárez-Martínez","doi":"10.1016/j.otorri.2025.512238","DOIUrl":"10.1016/j.otorri.2025.512238","url":null,"abstract":"<div><h3>Introduction</h3><div>Congenital profound bilateral hearing loss prevents the correct development of speech and voice. This study assesses certain acoustic parameters of the voice in order to determine their normality in the implanted population.</div></div><div><h3>Method</h3><div>Two population groups were studied. A control group consisting of 42 healthy pediatric patients, 22 boys and 20 girls, and a group of 22 pediatric patients, 11 boys and 11 girls with congenital profound hearing loss implanted bilaterally.</div><div>The variables median pitch, CPPS, <em>jitter</em> rap and <em>shimmer</em> apq5 were evaluated in an isolated phonation exercise and another in connected speech for the phoneme /a/ with the PRAAT program. Student's t-test and Wilcoxcon tests were applied.</div></div><div><h3>Results</h3><div>Significant intergroup differences were obtained for all variables in the vowel extracted from connected speech, but not in the sustained vowel. The hearing-impaired population showed some significant differences in the intra-group analysis. The experimental group showed better results in the vocal quality parameters, particularly jitter, shimmer and CPPS showed statistically significant differences.</div></div><div><h3>Conclusion</h3><div>Early bilateral implantation allows the cochlear implant user to approximate his acoustic values to normative values in terms of pitch, stability, quality and articulatory precision.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512238"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estratificación de la severidad de la sialoadenitis obstructiva crónica en función de su impacto en la calidad de vida","authors":"William Aragonés Sanzen-Baker ,&nbsp;José Miguel Villacampa Aubá ,&nbsp;Ignacio Alcalá Rueda ,&nbsp;Jessica Mireya Santillán Coello ,&nbsp;Gonzalo Díaz Tapia ,&nbsp;Carlos Cenjor Español ,&nbsp;Álvaro Sánchez Barrueco","doi":"10.1016/j.otorri.2025.512223","DOIUrl":"10.1016/j.otorri.2025.512223","url":null,"abstract":"<div><h3>Introduction</h3><div>Chronic Obstructive Sialadenitis (COS) is a debilitating condition characterized by recurrent inflammation of the salivary glands due to excretory obstruction, significantly impacting patients’ quality of life (QoL). The COS Quality of Life Questionnaire (COSQ) has been validated to evaluate QoL in affected patients and to monitor changes post-treatment.</div></div><div><h3>Materials and methods</h3><div>This study included two patient groups with COS-affected glands. The first group of 342 patients completed the COSQ before minimally invasive surgery, while the second group of 215 patients completed both the COSQ and a Visual Analog Scale (VAS). Scores were analyzed and stratified into four severity categories: mild, moderate, severe, and very severe, based on COSQ outcomes.</div></div><div><h3>Results</h3><div>COSQ scores were distributed as follows: mild (12.87%), moderate (37.13%), severe (34.5%), and very severe (15.21%). A significant correlation was observed between COSQ and VAS scores, particularly in the moderate and severe categories. Stratification allowed for identification of patients with severe symptoms, aiding in tailored management.</div></div><div><h3>Conclusion</h3><div>The COSQ effectively assesses QoL in COS patients and aids in stratifying severity. This stratification can guide clinicians in developing personalized treatment strategies, monitoring disease progression, and evaluating treatment outcomes.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512223"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated frontal sinus angiofibroma with external forehead deformity: A case report","authors":"Ali Tawfik,&nbsp;Ahmed Musaad Abd-Elfattah,&nbsp;Hisham Atef Ebada,&nbsp;Ahmad Muhammad Al-Arman,&nbsp;Donia Usama Hamza,&nbsp;Elsharawy Kamal","doi":"10.1016/j.otorri.2025.512227","DOIUrl":"10.1016/j.otorri.2025.512227","url":null,"abstract":"","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512227"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"¿Dónde se dirige la medicina del sueño? Un análisis de las unidades multidisciplinares en España","authors":"Laura Rodriguez Alcala ,&nbsp;Carlos O’Connor-Reina ,&nbsp;Carlos Egea ,&nbsp;F. Javier Puertas ,&nbsp;Milagros Merino ,&nbsp;Marina Carrasco ,&nbsp;Jose Maria Ignacio ,&nbsp;Peter Baptista ,&nbsp;Guillermo Plaza","doi":"10.1016/j.otorri.2025.512234","DOIUrl":"10.1016/j.otorri.2025.512234","url":null,"abstract":"","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512234"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"External ear affection in multiple myeloma","authors":"João Tavares Correia,&nbsp;Isabel Silva-Carvalho,&nbsp;Luís Meireles","doi":"10.1016/j.otorri.2025.512228","DOIUrl":"10.1016/j.otorri.2025.512228","url":null,"abstract":"","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512228"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144712491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complicaciones respiratorias en pacientes intervenidos por cáncer de cavidad oral, faringe y laringe en un hospital terciario","authors":"Marta Zabaleta López ,&nbsp;Belén Clemente Cuartero ,&nbsp;Pedro Díaz de Cerio Canduela ,&nbsp;Nisa Boukichou Addelkader ,&nbsp;Javier Ugedo Urruela","doi":"10.1016/j.otorri.2025.512236","DOIUrl":"10.1016/j.otorri.2025.512236","url":null,"abstract":"<div><h3>Background and objective</h3><div>The incidence of head and neck cancer (HNC) is directly related to tobacco and alcohol consumption, which explains why patients with HNC often present comorbidities, with chronic obstructive pulmonary disease (COPD) being an example. This condition is underdiagnosed, and various authors have demonstrated how its presence increases the incidence of respiratory complications in patients undergoing surgery for HNC.</div><div>We conducted a study aimed at evaluating respiratory complications in patients undergoing surgery for HNC at the San Pedro University Hospital (HUSP).</div></div><div><h3>Materials and methods</h3><div>A retrospective and descriptive study was conducted, including all adult patients diagnosed with oral cavity, pharyngeal, or laryngeal carcinoma who underwent surgery at the HUSP in Logroño between 2018 and 2021. Sociodemographic variables, medical history, previous pulmonary evaluation, and respiratory complications were recorded. A two-year follow-up was carried out.</div></div><div><h3>Results</h3><div>A total of 160 patients were included. 74.4% of the patients were men, and the mean age was 72<!--> <!-->years. 69.4% had a smoking habit, and 41.2% consumed alcohol. Comorbidities were documented in 82.5% of patients, with hypertension being the most prevalent, while COPD ranked fifth at 8.1%. Prior to surgery, only 16% of patients underwent spirometry, and fewer than 2% were evaluated in the pulmonology clinic.</div><div>Ten patients (6.25%) developed respiratory complications. Of these, 80% were smokers, and 30% had COPD, yet none had been evaluated in the pulmonology clinic prior to surgery. Diabetes mellitus and non-epidermoid cancer types were significantly associated with complications (<em>P</em> <!-->&lt;<!--> <!-->.05).</div></div><div><h3>Conclusions</h3><div>6.25% of patients who underwent surgery for HNC experienced respiratory complications. Although this rate is lower than those reported in other studies, it is noteworthy. This is especially relevant considering that, despite 30% of these patients having a prior diagnosis of COPD, none were evaluated before surgery to optimize treatment for this condition. These findings underscore the importance of identifying and managing COPD in patients with HNC and the need for further research in this area.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 4","pages":"Article 512236"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}