Acta otorrinolaringologica espanola最新文献

{"title":"Nebulized hyaluronic acid and xylitol based solution after turbinate radiofrequency ablation. A triple blind randomized multicentric clinical trial","authors":"Christian Calvo-Henríquez ,&nbsp;Ainhoa García-Lliberos ,&nbsp;Byron Maldonado-Alvarado ,&nbsp;Miguel Rodriguez-Iglesias ,&nbsp;David Lobo-Duro ,&nbsp;Juan Maza-Solano ,&nbsp;Serafín Sánchez-Gomez ,&nbsp;Isam Alobid","doi":"10.1016/j.otorri.2025.512218","DOIUrl":"10.1016/j.otorri.2025.512218","url":null,"abstract":"<div><h3>Objective</h3><div>This prospective, triple blind randomized clinical trial aims to specifically evaluate the effect of Aluneb® (hyaluronic acid plus xilitol) in the postoperative treatment of inferior turbinate radiofrequency in adults compared to nebulized isotonic saline.</div></div><div><h3>Methods</h3><div>Adults undergoing radiofrequency turbinate ablation were included. Treatment group received Aluneb® (hyaluronic acid plus xylitol) while the control group received nebulized isotonic saline for two months after treatment. Participants were studied the week before surgery (visit 0), and at 7, 15, 30 and 60 days after surgery. At all visits, participants underwent physical examination, rhinomanometry, SNOT-22, and visual analogue scale (VAS) of symptoms.</div></div><div><h3>Results</h3><div>34 participants were recruited. Crusts (endoscopy) were less in the Aluneb® hyaluronic acid plus xylitol group. Nasal crusting, epistaxis and nasal obstruction VAS were statistically significant lower. VAS for Rhinorrea, halitosis, cacosmia and pain and nasal resistance obtained lower self-reported values in the hyaluronic acid plus xilitol group, but these differences were not statistically significant.</div></div><div><h3>Conclusions</h3><div>Hyaluronic acid plus xilitol demonstrated promise in improving postoperative outcomes, future studies with larger sample sizes and different surgical techniques are encouraged.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512218"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epignatus: una causa inusual de obstrucción de vía aérea en el recién nacido","authors":"Mónica Rueda Vega,&nbsp;Alex Lowy Benoliel,&nbsp;Rosalía Souvirón Encabo","doi":"10.1016/j.otorri.2025.512232","DOIUrl":"10.1016/j.otorri.2025.512232","url":null,"abstract":"","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512232"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric maxillary expansion to treat nasal obstruction","authors":"Christian Calvo-Henriquez ,&nbsp;Pedro Martínez-Seijas ,&nbsp;Antonino Maniaci ,&nbsp;Juan Carlos Pérez-Varela ,&nbsp;Sandra Kahn ,&nbsp;Isam Alobid ,&nbsp;Stanley Y. Liu","doi":"10.1016/j.otorri.2025.512220","DOIUrl":"10.1016/j.otorri.2025.512220","url":null,"abstract":"<div><h3>Objective</h3><div>An often neglected cause of nasal obstruction is maxillary constriction. Maxillary expansion (ME) has been proven to decrease nasal resistance and increase nasal volume and airflow thus improving nasal obstruction symptoms both in adults and children. However, up to the present, studies have reported on patients with an orthodontic indication for ME, but not being treated for nasal obstruction. In this study we report a case series of pediatric patients who have been diagnosed with nasal obstruction attributed to maxillary constriction and who have been treated with ME.</div></div><div><h3>Methods</h3><div>Participants were consecutively selected. All children performed anterior active rhinomanometry and SN-5 questionnaire before and after ME. The longest follow-up visit to otolaryngology was recorded for this study. The inclusion criteria were children without adenoid or turbinate enlargement with persistent oral breathing and nasal obstruction confirmed through rhinomanometry. All included children were referred to their odontologist who performed ME only if it was safe for the patient.</div></div><div><h3>Results</h3><div>23 participants with a mean age of 10.1 (range 6.66–13.27) were included. 78.3% had been previously submitted to surgery to restore or improve nasal breathing. There was a mean decrease in nasal resistance of 0.13 Pa s/cm³, which is a reduction of 34.2% over the mean initial value (<em>P</em> &lt; .001). There was a statistically significant correlation between the amount of expansion and the decrease in nasal resistance (Rho = 0.75; <em>P</em> &lt; .001), and the increase in nasal airflow (rho = 0.71; <em>P</em> &lt; .001). Participants demonstrated a statistically significant decrease in their nasal symptoms measured with the SN5 questionnaire (<em>P</em> = .033).</div></div><div><h3>Conclusions</h3><div>These are preliminary results that should be managed with caution. Considering previous reports which included ME performed for orthodontic reasons, and the case series herein presented, which includes ME performed for nasal breathing, it seems that ME could be used with this latter objective. Future controlled studies should corroborate these results before producing a general recommendation.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512220"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cochleo-vestibular phenotype in patients with pathogenic variations in the ACTG1 gene","authors":"Rocío González-Aguado ,&nbsp;Jaime Gallo-Terán ,&nbsp;Eshter Onecha ,&nbsp;Carmelo Morales-Angulo","doi":"10.1016/j.otorri.2025.512217","DOIUrl":"10.1016/j.otorri.2025.512217","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the prevalence of pathogenic, likely pathogenic, and variants of unknown significance in the <em>ACTG1</em> gene among families with suspected bilateral sensorineural hearing loss of genetic origin. Additionally, the research aimed to elucidate the cochleovestibular phenotype of individuals carrying these variants.</div></div><div><h3>Methods</h3><div>A cohort of 365 unrelated families with sensorineural hearing loss participated in this study. Genetic analysis was conducted using Next-Generation Sequencing (NGS).</div></div><div><h3>Results</h3><div>The study identified c.94C&gt;A and c.721G&gt;A pathogenic variants in heterozygosity in the <em>ACTG1</em> gene among three probands. Two of these cases exhibited an autosomal dominant inheritance pattern, while the third was a <em>de novo</em> variant. Additionally, three other family members underwent genetic and audiological evaluations. Onset of hearing loss typically occurred between the first and second decades of life, initially affecting high frequencies and gradually extending to all frequencies. Treatment with hearing aids yielded favourable outcomes in all cases.</div></div><div><h3>Conclusions</h3><div>Pathogenic variants in the <em>ACTG1</em> gene were found to be rare in the studied population. Nonetheless, these variants should be considered in families presenting with postlingual bilateral sensorineural hearing loss, particularly when high-frequency hearing loss progressively worsens to profound levels.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512217"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consenso de la SEORL-CCC sobre la nomenclatura de los vaciamientos ganglionares cervicales","authors":"Laura Rodrigáñez ,&nbsp;Alexander Sistiaga ,&nbsp;Fernando López ,&nbsp;Eduardo Ferrandis ,&nbsp;Pedro Diaz de Cerio ,&nbsp;Pablo Parente ,&nbsp;Alejandro Castro ,&nbsp;Javier Gavilán","doi":"10.1016/j.otorri.2025.512231","DOIUrl":"10.1016/j.otorri.2025.512231","url":null,"abstract":"<div><div>There have been multiple classifications of cervical dissections for decades in the literature, but none of them has been completely imposed worldwide. After an exhaustive review of them, the Oncology and Head and Neck Surgery Commission of the SEORL-CCC has agreed on its own classification to standardize neck dissections to be able to compare results.</div><div>The Oncology and Head and Neck Surgery Commission of the SEORL-CCC considers that cervical dissections should be classified according to the type of surgical approach performed (functional or radical) and its extension pursuant to the anatomical areas dissected (comprehensive or selective).</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512231"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving voice quality in laryngectomy patients with botulinum toxin A","authors":"Gonçalo Caetano ,&nbsp;Filipa Morgado ,&nbsp;Joana Póvoa ,&nbsp;Francisco Branquinho","doi":"10.1016/j.otorri.2025.512222","DOIUrl":"10.1016/j.otorri.2025.512222","url":null,"abstract":"<div><h3>Introduction</h3><div>Tracheoesophageal (TEP) speech is the main voice rehabilitation method following laryngectomy. Pharyngoesophageal hypertonicity is one of the main causes for failure to achieve tracheoesophageal speech after laryngectomy. Botulinum toxin A (BTA) has been used to chemically denervate the pharyngeal musculature, and is an alternative to invasive surgical procedures. The aim of this work is to study the effectiveness and safety of this procedure.</div></div><div><h3>Material &amp; methods</h3><div>A retrospective cohort study from 2019 to 2023 was performed of 20 patients with failure to achieve a functional tracheoesophageal voice following laryngectomy. These patients undergone local pharyngoesophageal segment BTA injection. A total of 100 units of BTA were injected at 6 different sites, 3 in each side.</div><div>Perceptual ratings of voice quality were performed before and 72 h after BTA injection by a speech therapist using a 7-point equal-appearing interval scale.</div></div><div><h3>Results</h3><div>Speech quality mean rating (μ) improved from 2.05 before to 4.55 after BTA injection (<em>P</em> = .004), 17 (85%) patients had an improvement in postinjection perceptual TEP speech quality ratings, with scores in the good-to-excellent range (5–6 in the 7-point equal-appearing interval scale) in 12 patients (60%).</div><div>Three patients (15%) didn’t improve their voice quality, two of them with no discernible TEP speech.</div><div>No adverse effects were reported.</div></div><div><h3>Conclusions</h3><div>The majority of the patients enrolled in this study (85%) showed an improvement in TEP speech following BTA injection. This is a safe and effective method to improve TEP speech following laryngectomy.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512222"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Cochlear Implant in a Labyrinthine Facial Nerve Dehiscence”","authors":"Inés Tortajada Torralba ,&nbsp;Santiago Almanzo ,&nbsp;Carlos de Paula Vernetta","doi":"10.1016/j.otorri.2025.512226","DOIUrl":"10.1016/j.otorri.2025.512226","url":null,"abstract":"","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512226"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comentario al artículo: «Absceso periamigdalino recurrente en adultos: incidencia y factores de riesgo en una cohorte prospectiva longitudinal»","authors":"Francisco Javier García-Callejo,&nbsp;Miguel Juantegui Azpilicueta","doi":"10.1016/j.otorri.2025.512233","DOIUrl":"10.1016/j.otorri.2025.512233","url":null,"abstract":"","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512233"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of bariatric surgery in the treatment of obstructive sleep apnea in obese patients","authors":"Silvia Matarredona-Quiles ,&nbsp;Marina Carrasco-Llatas ,&nbsp;Paula Martínez-Ruíz de Apodaca ,&nbsp;Jose Ángel Díez-Ares ,&nbsp;Elena González-Turienzo ,&nbsp;José Dalmau-Galofre","doi":"10.1016/j.otorri.2025.512221","DOIUrl":"10.1016/j.otorri.2025.512221","url":null,"abstract":"<div><h3>Purpose</h3><div>To analyze the success rate of bariatric surgery in the treatment of obstructive sleep apnea (OSA) in obese patients and its related factors.</div></div><div><h3>Methods</h3><div>Longitudinal, prospective, single cohort study, with consecutive sampling including OSA patients aged 18–65 years intervened of bariatric surgery. An anamnesis regarding OSA, a complete upper airway (UA) exploration and a cardiorespiratory polygraphy (CRP) pre- and post-surgery were performed.</div></div><div><h3>Results</h3><div>Fifty-seven patients were included in this study. The overall surgical success and cure rates for bariatric surgery as a treatment for OSA were 61.4% and 52.6%, respectively. Factors predicting success were female sex (OR = 12.54; CI95% = 1.75–89.88, p = 0.012), age below 53 years old (OR = 7.24; CI95% = 1.48–35.51, p = 0.015) and pre-surgical weight below 105 kg (OR = 8.1; CI95% = 1.44–45.62, p = 0.018). Surgical success cases had lower weight and body mass index, greater weight loss, smaller postsurgical neck circumference and less palatal webbing, however these were not independent factors in the multivariate analysis.</div></div><div><h3>Conclusions</h3><div>Our results show that bariatric surgery is a feasible option for OSA treatment in obese patients, with a higher success rate in female, younger and thinner patients. Moreover, adipose tissue on the UA has been proven to decrease as a result of weight loss, although not correlated with surgery success in the treatment of OSA.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512221"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relación de la infección por el virus del papiloma humano con la aparición de segundas neoplasias y su repercusión pronóstica en los pacientes con carcinoma de orofaringe","authors":"Julia Gayà ,&nbsp;David Rubio ,&nbsp;Cristina Valero ,&nbsp;Cristina Vázquez-López ,&nbsp;Anna Holgado ,&nbsp;Miquel Quer ,&nbsp;Xavier León","doi":"10.1016/j.otorri.2025.512237","DOIUrl":"10.1016/j.otorri.2025.512237","url":null,"abstract":"<div><h3>Introduction</h3><div>This study analyzes the incidence of second neoplasms in patients with oropharyngeal carcinoma according to human papillomavirus (HPV) status and its impact on survival.</div></div><div><h3>Material and methods</h3><div>A retrospective analysis of 583 patients with oropharyngeal cancer treated between 1991 and 2023 was performed. A total of 112 patients (19.2%) had HPV-positive tumors.</div></div><div><h3>Results</h3><div>During the follow-up, 181 patients (31.0%) had a second neoplasm. The 5-year and 10-year second neoplasm-free survival for HPV-negative patients were 60.5% and 37.5%, significantly lower than in HPV-positive patients, which were 88.2% and 70.8%, respectively (<em>P</em> =.0001). The 84.4% of second and subsequent neoplasms in HPV-negative patients occurred in locations associated with tobacco and alcohol use, compared to 65.5% in HPV-positive patients (<em>P</em>=.001). In comparison to HPV-positive patients with no history of toxics consumption, HPV-positive patients with severe toxics consumption had a significantly higher risk of second neoplasms in locations associated with tobacco and alcohol use (<em>P</em> =.003). The competitive mortality associated with the appearance of second and subsequent neoplasms was significantly higher for patients with HPV-negative tumors (<em>P</em> =.0001).</div></div><div><h3>Conclusions</h3><div>Patients with HPV-positive oropharyngeal carcinomas have a lower risk of second neoplasms and lower competitive mortality associated with the appearance of second neoplasms compared with HPV-negative patients.</div></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512237"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}