Skull base surgery via extended endoscopic endonasal approach: Predictors of ear-nose-throat complications

IF 1.1 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola Pub Date : 2025-09-01 DOI:10.1016/j.otorri.2025.512264

Anna Penella , Alejandro Portillo , Ricardo Bartel , Jose María Caballero , Enric Cisa , Francesc Cruellas , Mireia Golet , Jose L Sanmillan , Alberto Torres , Xavier González-Compta

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引用次数: 0

Abstract

Objective

To identify predictive factors for ear-nose-throat (ENT) complications in patients undergoing skull base surgery via extended endoscopic endonasal approaches (EEEA).

Methods

Single-center retrospective observational study of a cohort of patients who underwent EEEA for skull base surgery between January 2015 and December 2021. Patients were stratified according to ENT complications.

Results

Sixty-one patients were included in the study: 37 women (60.66%) and 24 men (39.34%). Craniopharyngioma was the most frequently observed pathology (36%). 40 patients (65,57%) presented with ENT complications, being olfactory disturbance the most common complication (40,98%), followed by nasal obstruction (24,59%) and synechiae formation (18,03%). Logistic regression analysis revealed that younger age (P = .026) and excision of middle turbinates during EEEA surgery (P = .034) were independent factors with a significant association with ENT complications. Anterior septal deviation was an independent factor significantly associated with synechiae formation (P = .023).

Conclusion

Surgeons performing skull base surgery using EEEA should be aware that excision of middle turbinate, younger age and anterior septal deviation may be risk factors for ENT postoperative complications.

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经扩展内窥镜鼻内入路颅底手术：耳鼻喉并发症的预测因素

目的探讨经扩展内镜鼻内入路颅底手术患者耳鼻喉（ENT）并发症的预测因素。方法对2015年1月至2021年12月期间接受EEEA颅底手术的患者进行单中心回顾性观察研究。根据耳鼻喉科并发症对患者进行分层。结果共纳入61例患者，其中女性37例（60.66%），男性24例（39.34%）。颅咽管瘤是最常见的病理（36%）。40例（65.57%）患者出现耳鼻喉科并发症，其中嗅觉障碍最为常见（40.98%），其次为鼻塞（24.59%）和粘连形成（18.03%）。Logistic回归分析显示，年龄较小（P = .026）和EEEA手术中中鼻甲切除（P = .034）是耳鼻喉科并发症的独立因素，与耳鼻喉科并发症有显著相关性。前间隔偏曲是与粘连形成显著相关的独立因素（P = .023）。结论应用EEEA进行颅底手术时应注意中鼻甲切除、年龄偏小和前间隔偏曲可能是耳鼻喉科术后并发症的危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta otorrinolaringologica espanola OTORHINOLARYNGOLOGY-

CiteScore

1.40

自引率

20.00%

发文量

审稿时长

44 days

期刊介绍： Es la revista más importante en español dedicada a la especialidad. Ofrece progresos científicos y técnicos tanto a nivel de originales como de casos clínicos. Además, es la Publicación Oficial de la Sociedad Española de Otorrinolaringología y Patología Cérvico-Facial y está presente en los más prestigiosos índices de referencia.