{"title":"Understanding family formation and support in single mothers by choice: Insights from Swedish cohort studies.","authors":"Evangelia Elenis, Cecilia Mitt Holm, Ove Axelsson, Agneta Skoog Svanberg, Gunilla Sydsjö, Claudia Lampic","doi":"10.1111/aogs.70070","DOIUrl":"https://doi.org/10.1111/aogs.70070","url":null,"abstract":"","PeriodicalId":6990,"journal":{"name":"Acta Obstetricia et Gynecologica Scandinavica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145230944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yun Lin, Honghong Pan, Yupeng Chen, Chenshan Dong, Yijia Luo
{"title":"Transperineal ultrasound versus digital palpation: Identifying key parameters for objective pelvic floor muscle contraction assessment.","authors":"Yun Lin, Honghong Pan, Yupeng Chen, Chenshan Dong, Yijia Luo","doi":"10.1111/aogs.70065","DOIUrl":"https://doi.org/10.1111/aogs.70065","url":null,"abstract":"<p><strong>Introduction: </strong>The assessment of pelvic floor muscle function is crucial for managing pelvic floor dysfunctions, yet digital palpation is subjective and lacks reproducibility. This study aimed to correlate pelvic floor muscle contractility assessed by digital palpation with transperineal ultrasound measurements and evaluate the reliability of the Modified Oxford Scale and key ultrasound-derived parameters. By comparing these methods, the study sought to establish transperineal ultrasound as a reliable, objective, and non-invasive tool for assessing pelvic floor muscle contractility.</p><p><strong>Material and methods: </strong>A cross-sectional study was conducted at Shengli Provincial Hospital from November 2019 to July 2024. 442 of 512 screened women were included. Digital palpation was performed by two independent clinicians, and ultrasound measurements were conducted by two separate raters. Ultrasound raters were blinded to palpation (Modified Oxford Scale) findings. Transperineal ultrasound quantified multiple pelvic floor parameters, including proximal urethral axis angle change (maximal contraction-rest) and levator hiatus area. Inter-rater reliability was assessed using intraclass correlation coefficients for ultrasound measures and Cohen's kappa for MOS ratings. Correlations between ultrasound and palpation scores were analyzed using Spearman's rank. Cut-off values for key ultrasound parameters corresponding to palpation grades were determined via receiver operating characteristic curve analysis.</p><p><strong>Results: </strong>Significant correlations (p < 0.001) were found between ultrasound parameters and MOS scores, with the strongest correlations observed for proximal urethral axis angle change (maximal contraction-rest) (r<sub>s</sub> = 0.727) and proportional change in levator hiatus area (r<sub>s</sub> = 0.717). Ultrasound assessments showed high inter-rater reliability (intraclass correlation coefficient = 0.92 for proximal urethral axis angle change), while palpation demonstrated moderate agreement (Cohen's kappa = 0.55). Cut-off values for key parameters were derived, such as proximal urethral axis angle change <9.5° for absent contraction and >16.5° for strong contraction.</p><p><strong>Conclusions: </strong>Transperineal ultrasound demonstrated high reliability and provided an objective, non-invasive method for assessing pelvic floor muscle contractility. While digital palpation assessed functional strength, ultrasound visualized structural displacement during contraction. The two methods addressed complementary aspects of pelvic floor function, and their combined use enhanced clinical assessment.</p>","PeriodicalId":6990,"journal":{"name":"Acta Obstetricia et Gynecologica Scandinavica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lisa Tangnes Leeves, Trond Melbye Michelsen, Anne Flem Jacobsen, Aslak Vimme Solhoff, Nina Gunnes, Ingvil Krarup Sørbye
{"title":"Is indication for induction of labor associated with mode of delivery in term first births? A Norwegian registry-based study.","authors":"Lisa Tangnes Leeves, Trond Melbye Michelsen, Anne Flem Jacobsen, Aslak Vimme Solhoff, Nina Gunnes, Ingvil Krarup Sørbye","doi":"10.1111/aogs.70060","DOIUrl":"https://doi.org/10.1111/aogs.70060","url":null,"abstract":"<p><strong>Introduction: </strong>Few previous studies have examined the association between the indication for induction of labor (IOL) and the mode of delivery. To improve information for clinicians and women undergoing IOL, our study aimed to assess the association between the indication for IOL and the risk of cesarean and operative vaginal birth among nulliparous women with single cephalic term pregnancies. Furthermore, we examined whether associations varied by gestational length. Lastly, we evaluated reasons for cesarean and operative vaginal birth across indications for IOL.</p><p><strong>Material and methods: </strong>Data were extracted from the Medical Birth Registry of Norway from 2020 to 2021. We used the registered main indication for IOL. Multinomial logistic regression was applied to estimate relative risk ratios (RRRs) with associated 95% confidence intervals (CIs) of cesarean and operative vaginal birth versus spontaneous vaginal birth for the different IOL indications, using prelabor rupture of membranes (PROM) as the reference indication.</p><p><strong>Results: </strong>Risk of cesarean versus spontaneous vaginal birth was four times higher for women induced due to large fetus compared to women induced due to PROM (adjusted RRR: 4.39; 95% CI: 3.21 to 5.99). Indications such as maternal request, post-term pregnancy, oligo-/polyhydramnios, preeclampsia/hypertension, and diabetes were associated with a 40%-91% increased relative risk of cesarean versus spontaneous vaginal birth compared to PROM. Relative risk of operative vaginal versus spontaneous vaginal birth was increased by 23%-29% for oligo-/polyhydramnios, diabetes, and post-term pregnancy compared to PROM. Indication large fetus had similar relative risk ratios at all gestational lengths. Rate of operative delivery for fetal distress was highest for IOL due to intrauterine growth restriction (IUGR). For secondary outcomes, IOL due to IUGR had the highest proportions of cesarean and operative vaginal birth for fetal distress. Indication post-term pregnancy had the highest proportion of cesarean birth for prolonged labor, while large fetus had the highest proportion of operative vaginal birth for prolonged labor.</p><p><strong>Conclusions: </strong>Nulliparous women undergoing IOL for indications such as large fetus, post-term pregnancy, oligo-/polyhydramnios, preeclampsia/hypertension, and diabetes are at an elevated relative risk of cesarean versus spontaneous vaginal birth compared to IOL for PROM. In contrast, the relative risk of operative vaginal birth showed less variation by indication for IOL.</p>","PeriodicalId":6990,"journal":{"name":"Acta Obstetricia et Gynecologica Scandinavica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lyndsay Creswell, Pranav Pandya, Daniel Stott, Donald Peebles, George Attilakos, Eleni Nastouli, Haley Alchin, Kelly Pegoretti Baruteau, Raffaele Napolitano
{"title":"Parvovirus: Conservative management of fetal anemia and hydrops.","authors":"Lyndsay Creswell, Pranav Pandya, Daniel Stott, Donald Peebles, George Attilakos, Eleni Nastouli, Haley Alchin, Kelly Pegoretti Baruteau, Raffaele Napolitano","doi":"10.1111/aogs.70055","DOIUrl":"https://doi.org/10.1111/aogs.70055","url":null,"abstract":"<p><p>Following the COVID-19 pandemic, Northwestern Europe has experienced a marked increase in congenital parvovirus infections. This rise is attributed to social distancing measures which disrupted the usual seasonal variation of parvovirus B19. Fetal infection may cause severe anemia, thrombocytopenia, and hydrops fetalis, with significant risk of intrauterine death. Therefore, when acute parvovirus B19 infection is confirmed by maternal serology, serial ultrasound surveillance of the middle cerebral artery peak systolic velocity is recommended. Intrauterine transfusion remains the only established therapeutic option for cases of suspected fetal anemia or hydrops but carries risks of fetal loss and procedural-related complications including fetal hemorrhage and exsanguination. This review critically examines current literature on diagnosis, management, perinatal outcomes, and long-term neurodevelopmental sequelae following congenital parvovirus infection and intrauterine transfusion. Additionally, we report our tertiary fetal medicine center's experience during the 2024 epidemic, highlighting a novel conservative management approach for fetuses with parvovirus-related anemia and hydrops fetalis.</p>","PeriodicalId":6990,"journal":{"name":"Acta Obstetricia et Gynecologica Scandinavica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amanda Wei Mun Tan, Shi Hui Lee, Rehena Sultana, Deepak Mathur, Shephali Tagore, Manisha Mathur
{"title":"Accurate estimation of blood loss during cesarean deliveries: A secondary analysis of a randomized controlled trial comparing visual, quantitative and calculated approaches.","authors":"Amanda Wei Mun Tan, Shi Hui Lee, Rehena Sultana, Deepak Mathur, Shephali Tagore, Manisha Mathur","doi":"10.1111/aogs.70052","DOIUrl":"https://doi.org/10.1111/aogs.70052","url":null,"abstract":"<p><strong>Introduction: </strong>Effective measurement of blood loss during delivery is key in timely diagnosis of hemorrhage and prevention of postpartum hemorrhage (PPH). Blood loss estimation in cesarean deliveries is challenging, with the risk of contamination of measured blood with amniotic and irrigation fluid. The objective of this study is to assess the level of agreement of visually estimated blood loss (vEBL), quantitative blood loss (QBL), and calculated estimated blood loss (cEBL) in cesarean deliveries.</p><p><strong>Material and methods: </strong>This is a secondary analysis of a double-blinded, randomized controlled trial in the largest maternity unit in Singapore. Medical records from 200 patients enrolled in the prior study were analyzed, and their blood loss data reviewed for comparison. Blood loss estimation was assessed by vEBL (by the anesthetic and surgical teams), QBL (weighing of soiled gauzes and measuring fluid volume) and cEBL (formula-based calculation using pre- and postdelivery hemoglobin). Mean estimated blood losses (EBLs) obtained from all three methods were compared.</p><p><strong>Results: </strong>The use of vEBL yielded the lowest mean blood loss, lowest proportion of women with EBL ≥500 and ≥1000 mL, while cEBL was the highest for all three outcomes. Intraclass correlation ranged from 0.29 (low <0.5) between vEBL and cEBL to 0.68 (moderate: 0.5-0.75) between vEBL and QBL. On average, vEBL was 249.7 mL (95% CI: -822.7-323.3) less than QBL, and 287.9 mL (95% CI: -1143.9-568.0) less than cEBL. Although vEBL tends to underestimate blood loss compared with QBL and cEBL on average, the wide confidence intervals suggest that these differences are not statistically significant. As blood loss increased, vEBL was more likely to underestimate blood loss. Women with body mass index (BMI) ≥30 kg/m<sup>2</sup> were more likely to have EBL ≥500 mL by cEBL (OR 1.13, 95% CI: 1.05-1.21, p < 0.01). Women with longer operative duration have higher odds of having EBL ≥500 mL by vEBL or QBL.</p><p><strong>Conclusions: </strong>vEBL appears to grossly underestimate actual blood loss when compared with QBL and cEBL methods. Although the observed differences were not statistically significant, the wide confidence intervals suggest potential for substantial underestimation. Given this limitation, reliance solely on vEBL may lead to under-recognition and delayed management of PPH. Therefore, it is recommended that QBL and cEBL be incorporated into routine practice, particularly in high-risk cases. Clinicians should also account for factors that can influence EBL accuracy, such as operative duration and maternal BMI, when assessing blood loss and initiating interventions.</p>","PeriodicalId":6990,"journal":{"name":"Acta Obstetricia et Gynecologica Scandinavica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145147370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ragnheidur I Bjarnadottir, Thora Steffensen, Alexander K Smarason, Karin Pettersson, Nikos Papadogiannakis, Kristjana Einarsdottir, Johanna Gunnarsdottir
{"title":"Stillbirth in Iceland 1996-2021: Incidence and etiology.","authors":"Ragnheidur I Bjarnadottir, Thora Steffensen, Alexander K Smarason, Karin Pettersson, Nikos Papadogiannakis, Kristjana Einarsdottir, Johanna Gunnarsdottir","doi":"10.1111/aogs.70058","DOIUrl":"https://doi.org/10.1111/aogs.70058","url":null,"abstract":"<p><strong>Introduction: </strong>This study describes the stillbirth rate (SBR) in Iceland 1996-2021 and the causes of stillbirth according to the Stockholm classification of stillbirth, comparing time periods and gestational age (GA) groups.</p><p><strong>Material and methods: </strong>Clinical information was obtained from medical records of mothers who had stillbirths and their infants (n = 395). Infants were divided into groups according to GA at diagnosis of stillbirth: early preterm: ≥22 but <28 weeks (n = 140), late preterm: ≥28 but <37 weeks (n = 130), and term: ≥37 weeks (n = 125). Autopsy records and gross descriptions of the placenta were reviewed, and microscopic slides were reevaluated, and findings classified according to the Amsterdam Consensus. Primary and associated causes of death were assigned according to the Stockholm classification of stillbirth. The SBR, maternal and fetoplacental characteristics, and causes of death were compared between two 13-year periods (1996-2008 and 2009-2021) and between GA groups.</p><p><strong>Results: </strong>The SBR decreased from 4.10 to 2.88/1000 births (p = 0.009) between the two periods, but this decrease was limited to stillbirths diagnosed before term. Fewer stillbirths in the latter period were attributed to causes such as infection and placental abruption, and unexplained stillbirths reduced (0.59 vs. 0.16/1000, p < 0.05). The most common primary causes of stillbirth were reduced circulation in the umbilical cord (25.6%) and placental insufficiency (25.2%); both increased in incidence with more advanced gestation. Despite no difference in small-for-gestational-age infants, a larger percentage of stillbirths had low placental weight (21.3% vs. 30.3%, p = 0.002) and high fetoplacental ratio for GA (15.7% vs. 24.2%, p = 0.005) in the latter period, when a larger proportion of stillbirths were attributed to placental insufficiency (17.0% vs. 37.0%, p = 0.0002).</p><p><strong>Conclusions: </strong>The SBR decreased in the latter period due to a reduction in preterm stillbirth, whereas the SBR at term was unchanged. Reduced circulation of the umbilical cord and placental insufficiency were the commonest causes, and both increased with GA. Stillbirth due to infection and placental abruption, as well as unexplained stillbirths, decreased during the study period, whereas deaths attributed to placental insufficiency became more common, reflecting a lack of reduction of stillbirth at term in the latter period.</p>","PeriodicalId":6990,"journal":{"name":"Acta Obstetricia et Gynecologica Scandinavica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145136088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ann H Hansen, Lærke Priskorn, Niels Jørgensen, Nina O Nathan, Anja Pinborg, Anders Juul, Hanne K Hegaard
{"title":"Health behaviors in women conceiving by medically assisted reproduction vs natural conception: A cross-sectional study of 23,334 nulliparous women.","authors":"Ann H Hansen, Lærke Priskorn, Niels Jørgensen, Nina O Nathan, Anja Pinborg, Anders Juul, Hanne K Hegaard","doi":"10.1111/aogs.70051","DOIUrl":"https://doi.org/10.1111/aogs.70051","url":null,"abstract":"<p><strong>Introduction: </strong>Women conceiving by medically assisted reproduction (MAR) have a planned pregnancy, easing adherence to preconception recommendations, which they are expected to be highly motivated to comply with. However, little is known about the actual adherence among these women. Thus, we investigate to what extent women conceiving by MAR treatment adhere to recommendations from the Danish Health Authority regarding preconception health behavior and whether the adherence differs from that observed in women conceiving naturally. Secondly, we elucidate differences in health behavior in early pregnancy by mode of conception.</p><p><strong>Material and methods: </strong>A cross-sectional study using patient-reported questionnaire data from 23,443 nulliparous women collected in connection with their first-trimester nuchal translucency scan from 2012 to 2022 at Copenhagen University Hospital in Denmark. The women answered an online questionnaire including information on whether they conceived by MAR, which type of treatment, and their health behaviors before and during pregnancy. This included alcohol consumption, smoking, exercise, and intake of dietary supplements. Differences in health behaviors by mode of conception were analyzed using multiple logistic regression with adjustments for age and educational level.</p><p><strong>Results: </strong>Overall, 91% of women answered the questionnaire. Women who conceived by MAR (15%) had healthier preconception behaviors with significantly higher odds of taking folic acid supplements (adjusted odds ratio [aOR] 11.40, 95% confidence interval [CI]:9.95;13.04), stopping smoking due to planning of pregnancy (aOR 1.72, 95% CI:1.49;1.98), avoiding smoking (aOR 4.67, 95% CI:3.88;5.62), and avoiding alcohol (aOR 2.40 95% CI: 2.19;2.64) compared to women conceiving naturally. Adherence to recommendations among women who conceived by MAR was 30.6% for alcohol avoidance preconceptionally. In early pregnancy, women conceiving by MAR still had significantly healthier behaviors overall, except for exercise, which was lower (aOR 0.86, 95% CI: 0.80; 0.93), with 46.3% meeting the recommended weekly hours of exercise.</p><p><strong>Conclusions: </strong>Women conceiving by MAR generally exhibit healthy behaviors with high adherence to recommendations from the Danish Health Authority both preconceptionally and in early pregnancy, though only one third adhered to recommendations on avoiding alcohol preconceptionally, and half of the women adhered to recommendations on exercise in early pregnancy. Overall, women conceiving by MAR had healthier behaviors than women conceiving naturally.</p>","PeriodicalId":6990,"journal":{"name":"Acta Obstetricia et Gynecologica Scandinavica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145074149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charlotte L LeJeune, Gajane Santrosyan, Anna S Koning, Marjon A de Boer, Christianne A R Lok, Nelleke Ottevanger, Elyce Cardonick, Robert Fruscio, Roman G Shmakov, Lone Storgaard, Kristel Van Calsteren, Michael J Halaska, Frédéric Amant
{"title":"Vulvar and vaginal cancer during pregnancy: A pooled analysis of 15 cases from the International Network on Cancer, Infertility and Pregnancy and review of the literature.","authors":"Charlotte L LeJeune, Gajane Santrosyan, Anna S Koning, Marjon A de Boer, Christianne A R Lok, Nelleke Ottevanger, Elyce Cardonick, Robert Fruscio, Roman G Shmakov, Lone Storgaard, Kristel Van Calsteren, Michael J Halaska, Frédéric Amant","doi":"10.1111/aogs.70044","DOIUrl":"https://doi.org/10.1111/aogs.70044","url":null,"abstract":"<p><strong>Introduction: </strong>Vulvovaginal cancer in pregnancy is rare. Limited data complicate decision-making and patient counseling. Our review, coupled with new case data, fills a current gap in the literature and provides practical insights.</p><p><strong>Material and methods: </strong>Oncological and obstetric data of these pregnancies were examined by a case collection from the International Network on Cancer, Infertility and Pregnancy (INCIP) registry (vulvar n = 10, vaginal n = 5) and a literature review (vulvar n = 46, vaginal n = 37).</p><p><strong>Results: </strong>Although preoperative imaging of inguinofemoral lymph nodes is feasible, only 16.1% of vulvar cancer patients underwent ultrasound or MRI. Treatment was initiated during pregnancy for 69.1% of vulvar cancer and 28.4% of vaginal cancer patients. Surgical lymph node staging of vulvar cancer was postponed until after delivery in 10 cases, although uni- or bilateral lymphadenectomy during pregnancy was not associated with more complications. Delivery outcomes included a live birth rate of 96.4% for vulvar cancer and 50% for vaginal cancer due to the high rate of pregnancy terminations, with most births preterm. The overall 5-year survival rates for vulvar (81.3%) and vaginal (66.4%) cancer during pregnancy are comparable to nonpregnant populations, indicating that pregnancy does not adversely impact maternal prognosis.</p><p><strong>Conclusions: </strong>This study underscores the feasibility of adapting standard oncological care for pregnant patients, emphasizing multidisciplinary teams to optimize maternal and fetal outcomes.</p>","PeriodicalId":6990,"journal":{"name":"Acta Obstetricia et Gynecologica Scandinavica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thibaud Quibel, Anne Rousseau, Claire Thuillier, Mireille Ruiz, Patrick Rozenberg
{"title":"Risk of preterm delivery in women with a history of preterm labor successfully arrested by tocolytic treatment in their previous pregnancy.","authors":"Thibaud Quibel, Anne Rousseau, Claire Thuillier, Mireille Ruiz, Patrick Rozenberg","doi":"10.1111/aogs.70054","DOIUrl":"https://doi.org/10.1111/aogs.70054","url":null,"abstract":"<p><strong>Introduction: </strong>We aimed to determine if women with a history of preterm labor successfully arrested by tocolytic treatment who gave birth at term in their previous pregnancy are at an increased risk of preterm delivery in their next pregnancy.</p><p><strong>Material and methods: </strong>This case-control study included women with two consecutive singleton pregnancies who gave birth in the 15-year period of 2000-2014 at the tertiary hospital of Poissy-Saint-Germain. Cases (preterm labor [PTL] group) included all women admitted with intact membranes for preterm labor that was successfully arrested by tocolytic treatment between 24 + 0 and 34 + 6 weeks' gestation and who gave birth at term in the first of these two pregnancies. Two control groups were selected: (i) a spontaneous preterm delivery (sPTD) group including all women with a preterm delivery in the first pregnancy, and (ii) a term delivery (TD) group that included women selected among those who gave birth at term in the previous pregnancy. The primary outcome was the spontaneous preterm birth in the next pregnancy.</p><p><strong>Results: </strong>The PTL, sPTD, and TD groups included 114, 50, and 114 women, respectively. There were no significant differences for maternal age, body mass index, or relationship situation for both pregnancies. The mean (± SD) gestational age at the first study delivery was 39.1 (±1.2) weeks in the PTL group, 33.2 (±3.7) weeks in the PTD group, and 39.6 (±1.2) weeks in the TD group (p < 0.001 for each comparison). The delivery rate before 37 weeks of gestation in the subsequent pregnancy was 18.4% in the arrested PTL group, 34.0% in the PTB group, and 4.4% in the TD groups (p = 0.047 between arrested PTL and sPTD; p < 0,001 between arrested PTL and TD) and before 34 weeks, 6.1%, 16.0%, and 0%, respectively (p = 0.044 between arrested PTL and sPTD; p < 0,001 between arrested PTL and TD).</p><p><strong>Conclusions: </strong>Women with a history of preterm labor that was successfully arrested by tocolytic treatment, resulting in a TD, are at a higher risk of preterm delivery in their next pregnancy than women with no such history, but a lower risk than those with a preterm delivery in their last pregnancy.</p>","PeriodicalId":6990,"journal":{"name":"Acta Obstetricia et Gynecologica Scandinavica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beyond the diagnosis: The need for deeper psychosocial evaluation in single mothers by choice.","authors":"Mei Zhao, Fuhua Zhou","doi":"10.1111/aogs.70056","DOIUrl":"https://doi.org/10.1111/aogs.70056","url":null,"abstract":"","PeriodicalId":6990,"journal":{"name":"Acta Obstetricia et Gynecologica Scandinavica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}