Academic Journal of Chemistry最新文献_第5页

Nutrients Recovery From Aquaculture Wastewater Using Thermally Treated Gastropod Shells 利用热处理腹足类贝壳回收水产养殖废水中的营养物质

Academic Journal of Chemistry Pub Date : 2018-08-24 DOI: 10.32861/ajc.48.60.68

Adelagun Ruth Olubukola Ajoke

引用次数: 0

Ultra Sensitive UPLC Method Development and Validation for the Simultaneous Estimation of Tamsulosin Hydrochloride and Tolterodine Tartrate in Bulk and Pharmaceutical Dosage Form 盐酸坦索罗辛和酒石酸托特罗定原料药和制剂同时测定的超灵敏UPLC方法建立与验证

Academic Journal of Chemistry Pub Date : 2018-08-20 DOI: 10.32861/ajc.48.50.59

M. Sebaiy, S. El-Adl, M. Baraka, Mostafa S. Mohram, F. Ibrahim

{"title":"Ultra Sensitive UPLC Method Development and Validation for the Simultaneous Estimation of Tamsulosin Hydrochloride and Tolterodine Tartrate in Bulk and Pharmaceutical Dosage Form","authors":"M. Sebaiy, S. El-Adl, M. Baraka, Mostafa S. Mohram, F. Ibrahim","doi":"10.32861/ajc.48.50.59","DOIUrl":"https://doi.org/10.32861/ajc.48.50.59","url":null,"abstract":"A rapid, sensitive and accurate ultra-performance reversed phase liquid chromatographic method was developed for the simultaneous determination of tamsulosin and tolterodine in pure form and pharmaceutical preparation. The developed UPLC method is superior to conventional HPLC with respect to speed, resolution, solvent consumption and cost. The separation was carried out on RP C18 nucleosil (1.7 µm, 5 cm x 2 mm) using an isocratic mode in eluting Tamsulosin and Tolterodine at 1.54 min and 2.43 min respectively with a mobile phase composed of acetonitrile and 0.025N potassium phosphate buffer pH 3.50 (60%:40%), respectively. Chromatographic run time was 5 min with a flow rate 0.5 ml/min and UV detection at 220 nm. The linearity for tamsulosin and tolterodine were in the range of 2-20 µg/mL for both drugs, showed excellent recoveries for bulk and tablet dosage form with a very low LOD of 4.29 and 0.59 ng/mL for tamsulosin and tolterodine, respectively. The method has been validated for linearity, accuracy, precision, specificity, and limit of detection, limit of Quantification, robustness, and ruggedness. The method which was developed was validated as per the ICH guidelines. Finally, the method was compared statistically with reference methods indicating that there is no significant difference between them in respect of precision and accuracy.","PeriodicalId":6965,"journal":{"name":"Academic Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91292065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Chemical Modification of Expandable Graphite by Boric Acid and Its Flame Retarded Application in Polyethylene 硼酸对可膨胀石墨的化学改性及其在聚乙烯中的阻燃应用

Academic Journal of Chemistry Pub Date : 2018-07-15 DOI: 10.32861/ajc.47.34.39

Yaxin Meng, X. Pang, Wei-shu Chang

引用次数: 0

Non Destructive Methods (XRF and XRD) For Estimation of Impure Carbon and Heavy Metals in Printer Toner Ink Powder 无损法(XRF和XRD)测定打印机墨粉中不纯碳和重金属

Academic Journal of Chemistry Pub Date : 2018-07-15 DOI: 10.32861/ajc.47.40.49

A. Itodo, S. Benjamin, S. Ande

{"title":"Non Destructive Methods (XRF and XRD) For Estimation of Impure Carbon and Heavy Metals in Printer Toner Ink Powder","authors":"A. Itodo, S. Benjamin, S. Ande","doi":"10.32861/ajc.47.40.49","DOIUrl":"https://doi.org/10.32861/ajc.47.40.49","url":null,"abstract":"Air pollution constitutes the largest among all of the environmental risks. Dust and soot fragments forms components of air particulates, which are released into the air as extremely small particles or liquid droplets. The basis of this research is to characterize toner ink powder and wood soot samples and the detection of metallic pollutants in wood soot (WS) and printer toner ink (PIS) for their physicochemical properties (pH, conductivity, bulk density and moisture content) and instrumental analysis using scanning electron microscopy (SEM) and Fourier Transform Infrared (FTIR). Two non- destructive analytical techniques; Dispersive X-ray Fluorescence Spectrometry (ED-XRF) and X-ray Diffraction (XRD) were adopted for heavy metals (elemental) composition and mineralogy respectively. The pH of printer ink and wood soot shows higher pH value which indicates that they are alkaline. Low conductivity values were reported with low moisture, indicating easy fragmentation and spreading. The bulk density values for samples shows that the soot can be easily spread by air current to the environment. The EDS analysis indicates that the soot particles to be composed of primarily impure carbon, thus pointing at potential organic pollutants. The IR spectra show characteristics signals at 749.2 cm-1, 745.5 cm-1, 738.0 cm-1 and 745.5 cm-1 for wood soot and printer ink which correspond to C-H of aromatic group, 1703.4 cm-1, 1699.7 cm-1. The XRF analysis reveals high concentration of Chromium and other toxic metals. The mineralogical components of the soot and printer ink samples revealed the presence of associated minerals. Generally, levels of toxic metal exceed the permissible legislative limit for air samples.","PeriodicalId":6965,"journal":{"name":"Academic Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90126682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1