Acta Chemica Iasi最新文献_第2页

IL-24 AND IL-29 IN T2DM WITH AND WITHOUT DIABETIC FOOT ULCERS Il-24和il-29在伴有和不伴有糖尿病足溃疡的t2dm中的作用

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Acta Chemica Iasi Pub Date : 2022-01-01 DOI: 10.47743/achi-2022-2-0005

Eswadi Aya Refat, AL-Hellawi Zainab Hussein

{"title":"IL-24 AND IL-29 IN T2DM WITH AND WITHOUT DIABETIC FOOT ULCERS","authors":"Eswadi Aya Refat, AL-Hellawi Zainab Hussein","doi":"10.47743/achi-2022-2-0005","DOIUrl":"https://doi.org/10.47743/achi-2022-2-0005","url":null,"abstract":": Type 2 Diabetes Mellitus (T2DM) is a common chronic metabolic disease that spread worldwide. Uncontrolled T2DM cause many complications such as neurological diseases and lower limb amputations, in addition to other health problems. Insulin resistance and low-grade chronic inflammation in adipose tissue is a characteristic of people with obesity and diabetes. In fact, T2DM is inflammatory cytokines are involved in the pathophysiology of this disease. About 1.4 million Iraqis suffer from diabetes. In this study, some clinical characteristics and parameters level sixty patients with T2DM (32 male and 28 female) and thirty as controls were quantified. There are no significant differences between patients and controls in both age and BMI. There are expected significant increase in FBG, HbA1c and HOMA-IR in T2DM patients than healthy groups. There is a significant decline (p = 0.003) in serum IL-24 level in T2DM patients as compared with the controls. The low level of interleukin-24 in patients with T2DM has serious consequences. Despite the neuropathies in patients and the disease-causing nerve damage and non-healing of wounds, the decrease of this interleukin leads to may decrease in the patients’ immunity. The skin acts as a barrier against harmful microbes on several levels: colonization, pH, mechanical/physical and immunological IL-24 significant decrease (p < 0.001) in patients with type 2 diabetes and those who suffer from diabetic foot (DF) ulcers in particular affects the healing of ulcers and poorly in wound healing. There is a significant decline (p = 0.03) in serum IL-29 level in T2DM patients as compared with controls. The decreased IL-29 levels in patients may be defect in immune system particularly patients with T2DM, where IL-29 is secreted from T-helper that affects keratinocytes and activated against viruses. In contrast, an IL-29 level decrease in patients with DF ulcers induce an inflammatory response.","PeriodicalId":6958,"journal":{"name":"Acta Chemica Iasi","volume":"63 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74361043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

REVIEW: ARSENIC CONTAMINATION IN THE WORLD AND THE SPECIFIC CASE OF ARSENIC POLLUTED AREA OF TARNIȚA, NORTHEASTERN ROMANIA 综述:世界砷污染现状及罗马尼亚东北部tarniȚa砷污染地区的具体情况

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Acta Chemica Iasi Pub Date : 2022-01-01 DOI: 10.47743/achi-2022-1-0001

Z. C. Lagobo, V. Mambo, B. O. Yapo, V. P. Houenou, R. Necula, G. Drochioiu

引用次数: 0

SYNTHESIS AND ANTIOXIDANT ACTIVITY OF SOME CHALCONES CONTAINING N-ARYLACETAMIDE GROUP 含n -芳基乙酰胺基团查尔酮的合成及其抗氧化活性

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Acta Chemica Iasi Pub Date : 2021-01-01 DOI: 10.47743/ACHI-2021-1-0001

C. T. Nguyen, Na Pham-Thien Vo, Lien Nguyen, Khue To, Kiet Van Doan, H. Tran

引用次数: 1

PREPARATION AND CHARACTERIZATION OF ORGANOMONTMORILLONITE MODIFIED WITH ALKYLAMMONIUM CATION SURFACTANT: ADSORPTION EFFECT OF ZENONE 烷基铵阳离子表面活性剂改性有机蒙脱土的制备及表征:对苯酮的吸附效果

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Acta Chemica Iasi Pub Date : 2021-01-01 DOI: 10.47743/ACHI-2021-1-0003

H. Mekhalfi, S. Boudjemaa

{"title":"PREPARATION AND CHARACTERIZATION OF ORGANOMONTMORILLONITE MODIFIED WITH ALKYLAMMONIUM CATION SURFACTANT: ADSORPTION EFFECT OF ZENONE","authors":"H. Mekhalfi, S. Boudjemaa","doi":"10.47743/ACHI-2021-1-0003","DOIUrl":"https://doi.org/10.47743/ACHI-2021-1-0003","url":null,"abstract":"Montmorillonite (MMT) has been subjected to modification through ion-exchange reaction by hexadecyltrimethylammonium chloride (CTAC) ([(C16H33)N(CH3)3]Cl). The organomodified montmorillonite (OMM) was characterized by FT-IR, XRD, ATG, SEM, EDX, and Nitrogen adsorption measurements (BET). The basal spacing of unmodified bentonite, determined by XRD was 13.54 Å and after modification it increased up to 19.74 Å. FTIR and TG/DTG results showed a good amount of organic compound in organomodified MMT. Results of the SEM study revealed a tendency towards lump formation and agglomeration of the organomodified clay particles of montmorillonite. The adsorption of Zenone (ZE), a mycotoxin from animal food, onto MMT and OMMT was investigated. Effects of alkylammonium Cation Surfactant in binding ZE were studied. The intercalation of MMT with CTAC, the OMMT exhibited the highest adsorption rate of ZE (94.1%) which was much higher than that of MMT (11.21%). The adsorption isotherm parameters were calculated by using the Langmuir and Freundlich models and the data fitted better to the first one. All results indicate that OMMT has great potential to be a high-performance material to control ZE contamination. Hamoudi Mekhalfi, e-mail: bsouf77@yahoo.fr 32 Hamoudi Mekhalfi and Soufiane Boudjemaa","PeriodicalId":6958,"journal":{"name":"Acta Chemica Iasi","volume":"140 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80144319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PURELY CLEAR KINETIC SPECTROPHOTOMETRIC PROCESS FOR BROMHEXINE HYDROCHLORIDE EVALUATION IN PHARMACEUTICAL PREPARATIONS 纯透明动力学分光光度法评价药物制剂中盐酸溴己辛

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Acta Chemica Iasi Pub Date : 2021-01-01 DOI: 10.47743/achi-2021-2-0009

M. Al-Rufaie

{"title":"PURELY CLEAR KINETIC SPECTROPHOTOMETRIC PROCESS FOR BROMHEXINE HYDROCHLORIDE EVALUATION IN PHARMACEUTICAL PREPARATIONS","authors":"M. Al-Rufaie","doi":"10.47743/achi-2021-2-0009","DOIUrl":"https://doi.org/10.47743/achi-2021-2-0009","url":null,"abstract":"For the evaluation of Bromhexine hydrochloride (BRO) in pure drugs as well as their pharmaceutical preparations, a successful, sensitivity spectrophotometric method has been proved as well as checked. The methodology is focused on the creation of the Schiff base by pdimethylaminobenzaldehyde (PDMB), giving a bright yellow color to the reaction of the drug with the reagent . The yellow colored absorbance of species was assessed at its maximum absorption λmax of 420 nm. The Beer’s law was obeyed in the 10-60 μg/ml as the concentration range. The optical values were measured to be 8.693 x10 (L/mol/cm), 0.0005 (μg/cm2), Molar absorption coefficient as well as Sandell sensitivity respectively. The LOD and the LOQ for the suggested methodology were measured 3.280μg/ml, 4.114 μg/ml, respectively. To maximize the reaction conditions, all the variables were studied. The interference for the suggested method was identified in the existence of traditional excipients of pharmaceutics. By testing BRO in its pharmaceutical formulations, the validity of the approach was checked and objectively tested by statistical tests for its accuracy. Strong recoveries were obtained by the method developed; the results obtained in its pharmaceutical dosage forms were critically evaluated and used effectively for determining BRO.","PeriodicalId":6958,"journal":{"name":"Acta Chemica Iasi","volume":"328 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77197943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SIMULTANEOUS VOLTAMMETRIC DETERMINATION OF PARACETAMOL AND ASCORBIC ACID USING ACTIVATED GLASSY CARBON ELECTRODE: CYCLIC VOLTAMMETRY AND SQUARE WAVE VOLTAMMETRY STUDY 活性炭电极伏安法同时测定扑热息痛和抗坏血酸:循环伏安法和方波伏安法的研究

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Acta Chemica Iasi Pub Date : 2021-01-01 DOI: 10.47743/achi-2021-2-0008

Yared Shewarega, Dereje Yenealem, Fikadu Siyum

引用次数: 1

OCCURRENCE OF SELECTED ANTHROPOGENIC ORGANIC CONTAMINANTS IN DRINKING WATER FROM RURAL AREAS OF EASTERN ROMANIA 罗马尼亚东部农村地区饮用水中出现的某些人为有机污染物

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Acta Chemica Iasi Pub Date : 2021-01-01 DOI: 10.47743/achi-2021-2-0012

D. Dirtu, Manuela Pancu, Luminita Minea

引用次数: 0

A NEW SPECTROSCOPY METHOD FOR THE QUANTITATIVE DETERMINATION OF IRON(III) BASED ON CURCUMIN REAGENT 基于姜黄素试剂的光谱定量测定铁(iii)的新方法

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Acta Chemica Iasi Pub Date : 2021-01-01 DOI: 10.47743/ACHI-2021-1-0004

Q. Tran, Dinh-Vu Le

引用次数: 1

EVALUATION OF THE HAEMOSTATIC POTENTIALS OF CRUDE METHANOLIC LEAF EXTRACT OF PERSEA AMERICANA IN WISTAR RATS 美洲洋槐粗甲醇叶提取物对wistar大鼠的止血作用评价

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Acta Chemica Iasi Pub Date : 2021-01-01 DOI: 10.47743/ACHI-2021-1-0006

G. C. Anigbo, O. Onyekwere, P. I. Akwukwaegbu, A. Lackson, C. Bando, Obinna Okoye, Azubuike Bright Okoroafor, Patrick Esemaya, C. Patrick

{"title":"EVALUATION OF THE HAEMOSTATIC POTENTIALS OF CRUDE METHANOLIC LEAF EXTRACT OF PERSEA AMERICANA IN WISTAR RATS","authors":"G. C. Anigbo, O. Onyekwere, P. I. Akwukwaegbu, A. Lackson, C. Bando, Obinna Okoye, Azubuike Bright Okoroafor, Patrick Esemaya, C. Patrick","doi":"10.47743/ACHI-2021-1-0006","DOIUrl":"https://doi.org/10.47743/ACHI-2021-1-0006","url":null,"abstract":"To date, there is limited information on the coagulative and possible haemostatic potentials of Persea americana extract. In light of this, the study was aimed to investigate the haemostatic potentials of crude methanolic leaf extract of Persea americana in Wistar rats using standard analytical methods. A total of twenty-five adult male Wistar rats were arbitrarily distributed into five groups of five rats each and kept under suitable conditions for acclimatization and feeding. Group A was used as control and received feed and water only while various plant extracts (with concentrations 200, 400, 600 and 800 mg/kg) were orally administered on daily basis per body weight of animal in addition to normal feed and water for thirty days to the test groups B-E. After 4 weeks, the animals were sacrificed painlessly and blood samples were collected by retro-orbital plexus of Onyekachi A. Onyekwere, e-mail: onyekachi.onyekwere.au@gmail.com 82 George C. Anigbo et al. the median canthus of the eyes. The prothrombin and activated partial thromboplastin times (PT and APTT), clotting and bleeding times (CT and BT) and plasma fibrinogen concentration were determined. Phytochemical screening of the leaf extract revealed substantial percentage of alkaloids, saponins, tannins, flavonoids, steroids and phenols. Results of the haemostatic potential showed a dose-dependent significant decrease (P<0.05) in the PT, APTT, CT, and BT and a slightly increase (P<0.05) in the plasma fibrinogen concentration when compared with the control. This study suggested that the leaf extract of Persea Americana had a stimulatory effect on intrinsic and extrinsic properties of the coagulation cascade.","PeriodicalId":6958,"journal":{"name":"Acta Chemica Iasi","volume":"15 1","pages":"81-96"},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87170835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

INVESTIGATION ON MAGNETIC PROPERTIES AND CURIE TEMPERATURE OF SAMARIUM MODIFIED COBALT FERRITE 钐改性钴铁氧体磁性能及居里温度的研究

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Acta Chemica Iasi Pub Date : 2021-01-01 DOI: 10.47743/achi-2021-2-0010

Sita Rama Raju Padam, M. Dasari

引用次数: 0