Kyong Young Kim, Soo Kyoung Kim, Sang Soo Kim, Jung-Hwan Cho, Jae Min Lee, Jong-Ha Baek
{"title":"Clinical utility of 1-h post-load glucose in accelerating diagnosis of type 2 diabetes: a prospective cohort study.","authors":"Kyong Young Kim, Soo Kyoung Kim, Sang Soo Kim, Jung-Hwan Cho, Jae Min Lee, Jong-Ha Baek","doi":"10.1007/s00592-026-02692-7","DOIUrl":"https://doi.org/10.1007/s00592-026-02692-7","url":null,"abstract":"","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elena Succurro, Giuseppe Cersosimo, Paola Sarnelli, Francesco Brisinda, Ilaria Gattuso, Valeria Mazza, Giuseppe Fabiano, Fiorella Iorio, Roberta Arena, Giovanni Mazzitello, Ramona Nicotera, Maria Capria, Gianluigi Zaza, Michele Andreucci, Raffaele Mancini, Francesco Andreozzi
{"title":"Role of automated insulin delivery (AID) systems in glucose control in patients with diabetes mellitus undergoing dialysis in Calabria: AID-DIAL-CAL.","authors":"Elena Succurro, Giuseppe Cersosimo, Paola Sarnelli, Francesco Brisinda, Ilaria Gattuso, Valeria Mazza, Giuseppe Fabiano, Fiorella Iorio, Roberta Arena, Giovanni Mazzitello, Ramona Nicotera, Maria Capria, Gianluigi Zaza, Michele Andreucci, Raffaele Mancini, Francesco Andreozzi","doi":"10.1007/s00592-026-02690-9","DOIUrl":"https://doi.org/10.1007/s00592-026-02690-9","url":null,"abstract":"<p><strong>Aims: </strong>To describe the main glycemic outcomes and the Quality of Life (QOL) observed in a cohort of people with type 1 (T1D) or type 2 (T2D) insulin-treated diabetes under dialysis who started an Automated Insulin Delivery (AID) system.</p><p><strong>Methods: </strong>This is a longitudinal retrospective pilot real-world analysis of 14 individuals with T1D and T2D undergoing dialysis who began using an AID system to optimize glycemic control. All subjects used the MiniMed™ 780G system. Glucose metrics were collected at baseline, 3, 6, and 12 months after initiating the SmartGuard™ feature. The WHOQoL-Bref questionnaire was administered at the last follow-up to evaluate the QOL.</p><p><strong>Results: </strong>Out of the 14 people, 8 reached 1-year follow-up. Time in Range (TIR) increased from 63% at baseline to 69% at 12 months, Time Below Range < 70 mg/dL (TBR70) decreased from 0.3% to 0%, and Time Above Range > 250 mg/dL (TAR250) decreased from 6.7% to 3.9%. Seven out of eight subjects who reached a 12-month follow-up achieved all three glycemic targets for this fragile population (TIR > 50%, TBR70 < 1% and TAR250 < 10%). At the last follow-up, 58.3% of the users were satisfied or very satisfied with their health status, versus only 25% with the previous treatment, and 81.7% had a good or very good QOL, whereas only 8.3% had a good QOL, and no one had a very good QOL with the previous treatment.</p><p><strong>Conclusion: </strong>This pilot real-world study showed how the use of an AID system is safe and can help to improve the glycemic outcomes and the QOL of people with diabetes in dialysis.</p>","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Methodological and statistical inconsistencies compromise the efficacy and safety analyses of orforglipron.","authors":"Raafey Imran, Manahil Imran, Muhammad Roshan","doi":"10.1007/s00592-026-02696-3","DOIUrl":"https://doi.org/10.1007/s00592-026-02696-3","url":null,"abstract":"","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of CT-based perirenal structural characteristics with chronic kidney disease risk categories: the additional value of imaging.","authors":"Jinlei Fan, Liping Zuo, Peng Du, Runzhe Tian, Weijia Zhao, Jiqing Li, Yun Liu, Dexin Yu","doi":"10.1007/s00592-026-02691-8","DOIUrl":"https://doi.org/10.1007/s00592-026-02691-8","url":null,"abstract":"<p><strong>Aims: </strong>Chronic kidney disease (CKD) is a major complication of type 2 diabetes mellitus (T2DM), yet diagnosis remains challenging. This study investigated whether perirenal structural features on CT offer diagnostic value for identifying T2DM patients at higher CKD risk.</p><p><strong>Methods: </strong>494 T2DM patients who underwent plain abdominal CT were enrolled from 2 institutions. Patients were stratified into lower or higher CKD risk categories per KDIGO 2012 guidelines. The grade of perirenal fat stranding, fascia thickening, perirenal fat thickness, and Mayo adhesive probability were evaluated. Predictors were selected via Lasso and logistic regression to build clinical, imaging, and combined nomogram models.</p><p><strong>Results: </strong>Perirenal fat stranding (grade 2) and fascia thickening constituted the imaging model for higher CKD risk, while systolic blood pressure and haemoglobin formed the clinical model. The nomogram incorporating these 4 factors achieved concordance indices of 0.888 (95% CI: 0.850-0.927), 0.830 (95% CI: 0.731-0.929), and 0.791 (95% CI: 0.681-0.900) in the training, internal, and external validation sets, respectively, for identifying T2DM patients at increased CKD risk.</p><p><strong>Conclusions: </strong>T2DM patients exhibiting perirenal fat stranding and fascia thickening should be identified as being at higher CKD risk. Further renal function tests are recommended to detect abnormalities early and be integrated promptly into standardised CKD management protocols.</p>","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Chico, Eva Aguilera-Hurtado, Mercè Albareda, Jesús Moreno-Fernández, Pilar Beato-Vibora, Elsa Fernández-Rubio, Martín Cuesta, Amparo Bartual, Francisco Javier Ampudia-Blasco, Orosia Bandrés, Jessica Ares, María Teresa Rivero, María José Picón-César
{"title":"A multicenter prospective evaluation of the benefits of Dexcom ONE + in subjects with type 2 diabetes on insulin therapy beyond glycemic control: results from the LIFE-ONE study.","authors":"Ana Chico, Eva Aguilera-Hurtado, Mercè Albareda, Jesús Moreno-Fernández, Pilar Beato-Vibora, Elsa Fernández-Rubio, Martín Cuesta, Amparo Bartual, Francisco Javier Ampudia-Blasco, Orosia Bandrés, Jessica Ares, María Teresa Rivero, María José Picón-César","doi":"10.1007/s00592-026-02682-9","DOIUrl":"https://doi.org/10.1007/s00592-026-02682-9","url":null,"abstract":"","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147662063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ivan Krecak, Marija Valovicic Krecak, Tina Marketin, Marta Marcinkovic, Hrvoje Holik, Marko Skelin, Josipa Budimir, Marko Lucijanic, Sanja Klobucar
{"title":"Differentiating polycythemia vera from sodium-glucose cotransporter 2 inhibitor-associated polycythemia.","authors":"Ivan Krecak, Marija Valovicic Krecak, Tina Marketin, Marta Marcinkovic, Hrvoje Holik, Marko Skelin, Josipa Budimir, Marko Lucijanic, Sanja Klobucar","doi":"10.1007/s00592-026-02651-2","DOIUrl":"https://doi.org/10.1007/s00592-026-02651-2","url":null,"abstract":"","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}