Acta Diabetologica最新文献

{"title":"Retrospective cohort study on treatment outcomes of early vs late onset gestational diabetes mellitus.","authors":"Riccardo Candido, Barbara Toffoli, Giulia Manfredi, Anna Turisani, Veronica Delfauro, Alessandra Petrucco, Chiara Gottardi, Elena Manca, Iris Buda, Laura Travan, Gianpaolo Maso, Stella Bernardi","doi":"10.1007/s00592-024-02405-y","DOIUrl":"https://doi.org/10.1007/s00592-024-02405-y","url":null,"abstract":"<p><strong>Background: </strong>Gestational diabetes mellitus (GDM) affects roughly 14% of pregnancies, its prevalence is increasing, and it is associated with a significant risk of complications for both mother and offspring. A high proportion of women with GDM can be detected early in pregnancy. In Italy, early GDM screening occurs in a selective way, as it is performed only in the presence of important risk factors. It remains to be elucidated not only how and when to diagnose early GDM but especially whether to treat it. This study aimed to compare the characteristics and complications of early vs late GDM as assessed and treated in a real-world setting, according to the Italian guidelines of the Istituto Superiore di Sanità.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study in women with GDM delivering singletons between 2017 and 2021.</p><p><strong>Results: </strong>Women with early GDM had higher BMI and a higher proportion of Middle Eastern or African women. Early GDM was independently associated with the use of insulin (p < 0.001). It required also higher doses of insulin, possibly due to the higher BMI. Early GDM was also independently associated with higher post-prandial (after dinner) glucose levels during the 3° trimester (p = 0.04). Nevertheless, early GDM women achieved glucose targets and put on less weight during gestation. Early GDM was independently associated with preeclampsia (p = 0.05). Otherwise, there were no other differences between early and late GDM in terms of pregnancy complications. After delivery, early GDM was independently associated with abnormal glucose tolerance.</p><p><strong>Conclusions: </strong>Early GDM women exhibited more severe GDM features. However, after achieving recommended glucose and body weight targets, there were no substantial differences between early and late GDM in terms of pregnancy complications apart from preeclampsia. These data support diagnosis and treatment of women with early GDM.</p>","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive markers of early endothelial dysregulation in type-1 diabetes: a meta-analysis.","authors":"Ranmali Ranasinghe, Michael Mathai, Mohammed Abdullah Alshawsh, Anthony Zulli, Ranmali Ranasinghe","doi":"10.1007/s00592-024-02401-2","DOIUrl":"https://doi.org/10.1007/s00592-024-02401-2","url":null,"abstract":"<p><strong>Background: </strong>This study identifies a new set of salient risk factors that may trigger danger signals of vascular dysregulation in T1D. Vascular abnormalities and impairment of CVD is a major adverse effect of T1D, particularly affecting children, adolescents and young adults.</p><p><strong>Methods: </strong>The patients of T1D were compared with the healthy control (HC) for the risk factors of vascular dysregulation in published studies from year 2013 to 2023. The PubMed, Web of Science and Google Scholar databases were searched from 1/1/2013 to 1/9/2023. The risk of bias was assessed with the Cochrane (ROBINS-I ) tool, relevant to clinical subjects. A random effects model was followed and analysed by RevMan 5.4 and GraphPad Prism software.</p><p><strong>Results: </strong>80 relevant case-control studies having 7492 T1D patients and 5293 HC were included. The age and sex-matched HC consisted of persons free of disease and not under any medication while clinical subjects of < 40 years were included. 28 risk factors were grouped into six primary outcome models, all of which favoured the T1D synonymous with a high risk of CVD.</p><p><strong>Conclusion: </strong>Our findings have strong implications for improving the quality of life and health economics related to vascular disease in T1D. HbA1c% is the most effective biomarker, followed by FBG, LDL-c, AI%, sICAM-1, and FMD% which could be evaluated with a simple blood test or non-invasive techniques. These may serve dual purposes as biomarkers of rapid diagnosis that could offer prospective tailor-made therapeutics for T1D. (Protocol registered at https://www.crd.york.ac.uk/prospero/CRD42022384636 ).</p>","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of new onset diabetes on cardiovascular risks in orthotopic liver transplant recipients: findings from the COLT study.","authors":"Alfredo Caturano, Anna di Martino, Gaetana Albanese, Carmine Coppola, Vincenzo Russo, Kateřina Koudelková, Raffaele Galiero, Luca Rinaldi, Celestino Sardu, Aldo Marrone, Marcellino Monda, Raffaele Marfella, Jan Gojda, Ferdinando Carlo Sasso, Teresa Salvatore","doi":"10.1007/s00592-024-02406-x","DOIUrl":"https://doi.org/10.1007/s00592-024-02406-x","url":null,"abstract":"<p><strong>Background: </strong>Orthotopic liver transplantation (OLT) has greatly improved short-term survival for end-stage liver disease. However, cardiovascular events (CVE) still pose a significant threat to long-term post-transplant health. Aim of this study is to assess the occurrence of long-term cardiovascular events and whether it relates to new-onset diabetes after liver transplantation (NODALT).</p><p><strong>Methods: </strong>We conducted a multicentric retrospective analysis of adult OLT recipients with regular follow-up visits spanning from January 1995 to December 2020. Data collection included anamnestic, clinical, anthropometric, and laboratory data from two centers. NODALT was diagnosed following ADA guidelines. The primary outcome was incident CVE (a composite of fatal and non-fatal stroke and myocardial infarction). CVE occurrence was analyzed in relation to NODALT diagnosis, along with clinical characteristics associated with its development.</p><p><strong>Results: </strong>Ninety-three eligible Caucasian patients, with a median age of 57.0 years (IQR: 49.0-62.0, 69.9% male), were enrolled. Over the median follow-up period of 100.5 months, 29 patients (31.2%) developed NODALT, and 14 patients (15.1%) developed any CVE, with 9 being in the NODALT group. A significant association between NODALT and cardiovascular complications was confirmed by both generalized estimating equation (OR 5.31; 95% CI 1.59-17.72, p = 0.006) and Kaplan-Meier analysis (log-rank = 0.046). Metabolic syndrome and impaired fasting glucose were identified as baseline risk factors for the incident NODALT (OR 5.75; 95% CI 1.44-22.92, p = 0.013 and OR 7.29; 95% CI 1.46-36.41, p = 0.015, respectively).</p><p><strong>Conclusions: </strong>Post-OLT cardiovascular events are less frequent than previously reported but are notably linked to NODALT, highlighting the interplay between metabolic syndrome and impaired fasting glucose.</p>","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A qualitative study of the mental health outcomes in people being treated for obesity and type 2 diabetes with glucagon-like peptide-1 receptor agonists.","authors":"Aureliane C S Pierret, Madeleine Benton, Piya Sen Gupta, Khalida Ismail","doi":"10.1007/s00592-024-02392-0","DOIUrl":"https://doi.org/10.1007/s00592-024-02392-0","url":null,"abstract":"<p><strong>Objective: </strong>Obesity and type 2 diabetes (T2D) are associated with increased rates of mental disorders, particularly depression, anxiety and binge-eating disorder. GLP-1 receptor agonists are a novel class of pharmacological agents for obesity and T2D. We aimed to describe participants' experiences of GLP-1 receptor agonists on their mental health.</p><p><strong>Methods: </strong>Qualitative, individual, semi-structured interviews were conducted in nine participants who were prescribed GLP-1 receptor agonists for the treatment of obesity and/or T2D. Mental health status was measured at time of GLP-1 receptor agonist initiation and assessed again at 12-16 weeks when the semi-structured interview took place. Data were analysed using reflexive thematic analysis.</p><p><strong>Results: </strong>Three main themes were generated from the analysis: (1) acceptance of negative side effects for long term physical health benefits; (2) reflections on the diverse impact on mental health; (3) reduced appetite and increased control of eating behaviours.</p><p><strong>Discussion: </strong>Overall, participants with obesity and/or T2D described a positive impact of GLP-1 receptor agonists on their mental health, especially perception of improved control of eating behaviours. This suggests GLP-1 receptor agonists should be further studied for their potential effectiveness for treatment of binge-eating disorder.</p>","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In blood we trust: anemia as a negative healing prognostic factor in diabetic foot patients","authors":"Francesco Giangreco,&nbsp;Elisabetta Iacopi,&nbsp;Vittorio Malquori,&nbsp;Letizia Pieruzzi,&nbsp;Chiara Goretti,&nbsp;Alberto Piaggesi","doi":"10.1007/s00592-023-02188-8","DOIUrl":"10.1007/s00592-023-02188-8","url":null,"abstract":"<div><h3>Aim</h3><p>Anemia has been associated with severity of diabetic foot (DF) disease. Our study aimed to evaluate whether the presence of anemia could decrease the healing chances in DF.</p><h3>Methods</h3><p>We retrospectively analyzed all patients admitted in our department in 2021 for DF, dividing them according to presence (Group A) or absence (Group B) of anemia. Groups were compared for clinical and demographic characteristics, procedures and outcomes: healing rate (HR) at 6 months, healing time (HT) and recurrence rate (RR) at 12 months.</p><h3>Results</h3><p>We sorted out data from 196 consecutive patients: 114 (58%) in Group A and 82 (42%) in B. Group A had a higher male prevalence and a longer duration of disease. Group A showed lower hemoglobin concentration (10.3 ± 1.3 g/dL vs 13.1 ± 1.4 g/dL, <i>p</i> &lt; 0.002) and red blood cells count (3.4 ± 0.5 × 10⁶/mL vs 4.8 ± 0.6 × 10⁶/mL, <i>p</i> = 0.004). Group A presented a lower HR (55.2% vs 76.8%, <i>p</i> = 0.0028), no differences in HT and a higher RR (23.6% vs 17.1%, <i>p</i> &lt; 0.02). Cox’s logistic regression on healing confirmed the negative impact of anemia: hazard ratio 2.8 (CI 95% 1.4–5.4, <i>p</i> = 0.0037).</p><h3>Conclusions</h3><p>Anemia is frequent in DF and associates to a reduction in healing chances and an increase in recurrences representing an independent predictor of healing failure.</p></div>","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":"61 2","pages":"245 - 251"},"PeriodicalIF":3.1,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41231500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GLP-1RAs inhibit the activation of the NLRP3 inflammasome signaling pathway to regulate mouse renal podocyte pyroptosis","authors":"Xiang Li,&nbsp;Xiao Jiang,&nbsp;Mei Jiang,&nbsp;Zhi-feng Wang,&nbsp;Tao Zhao,&nbsp;Si-ming Cao,&nbsp;Qiu-Mei Li","doi":"10.1007/s00592-023-02184-y","DOIUrl":"10.1007/s00592-023-02184-y","url":null,"abstract":"<div><h3>Objective</h3><p>Podocytes are closely related to renal function as an important part of the glomerulus. The reduction and damage of podocytes lead to further decline of renal function and aggravate the progression of DKD. Glucagon-like peptide-1 receptor agonists (GLP-1RAS) have recently attracted great attention in improving podocyte dysfunction, but the specific mechanism remains uncertain.</p><h3>Methods</h3><p>We used mouse kidney podocyte MPC5 to construct a high-glucose injury model. Cell viability was detected by the MTT method; RT-qPCR and western blotting were used to detect the expressions of NF-κB p65, NLRP3, GSDMD, N-GSDMD, caspase-1 and cleaved-caspase-1, and we used ELISA to detect the expressions of inflammatory factors IL-1β and IL-18.</p><h3>Results</h3><p>Our results showed that high glucose decreased podocyte survival, while liraglutide and semaglutide increased podocyte survival under high glucose. Liraglutide and semaglutide can inhibit the expression of pyroptosis-related genes and proteins and also inhibit the expression of inflammatory factors IL-1β, IL-18 increase.</p><h3>Conclusion</h3><p>The protective effect of liraglutide and semaglutide on podocytes may be achieved by regulating the NLRP3 inflammasome pathway and inhibiting pyroptosis, and there were no significant differences between the two GLP-1RAs (liraglutide and semaglutide) in inhibiting podocyte pyroptosis.</p></div>","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":"61 2","pages":"225 - 234"},"PeriodicalIF":3.1,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41231499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Family structures and parents’ occupational models: its impact on children’s diabetes","authors":"Pauline Schlarb,&nbsp;Janina M. Büttner,&nbsp;Sascha R. Tittel,&nbsp;Kirsten Mönkemöller,&nbsp;Esther Müller-Godeffroy,&nbsp;Claudia Boettcher,&nbsp;Angela Galler,&nbsp;Gabriele Berger,&nbsp;Burkhard Brosig,&nbsp;Reinhard W. Holl","doi":"10.1007/s00592-023-02187-9","DOIUrl":"10.1007/s00592-023-02187-9","url":null,"abstract":"<div><h3>Aims</h3><p>This study examines how family-related factors influence the management of children and adolescents with type 1 diabetes (T1DM). We investigate the relationship between family patterns, parental work schedules and metabolic control.</p><h3>Materials and methods</h3><p>We analysed data from a nationwide diabetes survey (DPV) focusing on HbA1c, severe hypoglycaemia, diabetic ketoacidosis, hospital admissions and inpatient treatment duration. We used linear regression and negative binomial regression models. Our study includes 15,340 children under the age of 18 with data on family structure and parental division of labour.</p><h3>Results</h3><p>Children from two-parent households have better HbA_1c outcomes than children from single-parent, blended or no-parent households (<i>p</i> &lt; .0001). Higher HbA_1C levels are associated with children living with an unemployed father, as opposed to those with full-time working parents or with a full-time working father and a part-time working mother (<i>p</i> &lt; .001).</p><h3>Conclusions</h3><p>These findings emphasise the importance of carefully considering family structure and working time models in the management of paediatric T1DM. Our results highlight risk factors within the family environment and emphasise the need for family-focused counselling of high-risk patients or severe cases in clinical practice.</p></div>","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":"61 2","pages":"235 - 244"},"PeriodicalIF":3.1,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10866793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41231498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual reality's impact on children with type 1 diabetes: a proof-of-concept randomized cross-over trial on anxiety, pain, adherence, and glycemic control","authors":"Noah Gruber,&nbsp;Moran Shemesh-Iron,&nbsp;Ethel Kraft,&nbsp;Karen Mitelberg,&nbsp;Elinor Mauda,&nbsp;Michal Ben-Ami,&nbsp;Kineret Mazor-Aronovitch,&nbsp;Yael Levy-Shraga,&nbsp;Neriya Levran,&nbsp;Noah Levek,&nbsp;Eyal Zimlichman,&nbsp;Orit Pinhas-Hamiel","doi":"10.1007/s00592-023-02195-9","DOIUrl":"10.1007/s00592-023-02195-9","url":null,"abstract":"<div><h3>Aims</h3><p> Assess the effectiveness of virtual reality (VR) technology, in reducing pain and anxiety, and improving adherence and glycemic control among children with type 1 diabetes (T1D).</p><h3>Methods</h3><p>Children with T1D, managed with continuous glucose monitoring and insulin pumps, were recruited for a randomized cross-over trial. Children were randomized to one of two interventions for diabetes management: group 1 used VR glasses first and group 2 listened to vocal-guided affective imagery first (audio). After 1 month, the interventions were crossed over. The outcome measures included pain and anxiety assessment, adherence, glycemic control, and patient-reported outcome measures (PROMs) of VR satisfaction and effectiveness.</p><h3>Results</h3><p> Forty children, mean age 11.4 ± 1.8 years, were participated. During the VR part, the monthly mean pain score compared to the baseline improved in both groups by 30% (<i>p</i> = 0.03). A 14% reduction in the state anxiety score was observed from baseline to 1 month in both groups (<i>p</i> = 0.009). Glycemic control measures including time in range, time above range, and glucose management indicator improved in both groups during VR part (<i>p</i> &lt; 0.004 for all), compared to audio part. After one month, the patient-reported outcome measure (PROM) of satisfaction and effectiveness was sixfold higher after 1 month in group 1 compared to group 2 (<i>p</i> = 0.002). Adherence improved for both groups.</p><h3>Conclusions</h3><p>VR was shown to be effective in reducing pain and anxiety, improving adherence, PROM, and glycemic control among children with T1D. We suggest incorporating VR technology in pediatric diabetes clinics to facilitate and improve coping and management of diabetes.</p><h3>Trial registration</h3><p>Trial registration number and date of registration for prospectively registered trials:ClinicalTrials.gov Identifier: NCT05883267, May 10th, 2023.</p></div>","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":"61 2","pages":"215 - 224"},"PeriodicalIF":3.1,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41231501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic effect between pre-pregnancy smoking and assisted reproductive technology on gestational diabetes mellitus in twin pregnancies","authors":"Lingyu Zhang,&nbsp;Yan Huang,&nbsp;Mingjin Zhang,&nbsp;Yanqi Jin","doi":"10.1007/s00592-023-02183-z","DOIUrl":"10.1007/s00592-023-02183-z","url":null,"abstract":"<div><h3>Aim</h3><p>Women with twin pregnancies have an increased risk of gestational diabetes mellitus (GDM). Assisted reproductive technology (ART) and pre-pregnancy smoking were both associated with GDM. However, the relationships between pre-pregnancy smoking and ART and GDM in twin pregnancies were unclear. Herein, this study aims to explore the roles of pre-pregnancy smoking and ART in GDM among women with twin pregnancies.</p><h3>Methods</h3><p>Data of women with twin pregnancies were extracted from the National Vital Statistics System (NVSS) database in 2016–2020 in this retrospective cohort study. Univariate and multivariate logistic regression analyses were used to explore the associations between pre-pregnancy smoking and ART and GDM in women with twin pregnancies. The evaluation index was odds ratios (ORs) with 95% confidence intervals (CIs). Subgroup analysis of age and BMI was also performed.</p><h3>Results</h3><p>A total of 19,860 (9.15%) women had GDM in our study. After adjusting for covariates, we found that receiving ART was associated with high odds of GDM [OR = 1.41, 95% CI (1.34–1.48)], while pre-pregnancy smoking combined with ART was associated with higher odds of GDM [OR = 1.66, 95% CI (1.14–2.42)]. In addition, these relationships were also found in women who aged ≥ 35 years old [OR = 1.98, 95% CI (1.14–3.44)] and with BMI ≥ 25 kg/m² [OR = 1.69, 95% CI (1.11–2.55)].</p><h3>Conclusion</h3><p>Pre-pregnancy smoking may further increase the risk of GDM from ART in women with twin pregnancies. In clinical, women who are ready to receive ART treatment are recommend to quit smoking, which may reduce the risk of GDM and prevent adverse pregnancy outcomes.</p></div>","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":"61 2","pages":"205 - 214"},"PeriodicalIF":3.1,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41187728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gremlin-1 in pregnancy and postpartum: health risk monitoring of women with gestational diabetes mellitus","authors":"Tomoyuki Kawada","doi":"10.1007/s00592-023-02196-8","DOIUrl":"10.1007/s00592-023-02196-8","url":null,"abstract":"","PeriodicalId":6921,"journal":{"name":"Acta Diabetologica","volume":"61 1","pages":"135 - 136"},"PeriodicalIF":3.1,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41187727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}