{"title":"Structural characterization of potential modulation sites in the extracellular domain of the prokaryotic pentameric proton-gated ion channel GLIC","authors":"Z. Fourati, M. Delarue, L. Sauguet","doi":"10.2210/PDB4QH1/PDB","DOIUrl":"https://doi.org/10.2210/PDB4QH1/PDB","url":null,"abstract":"","PeriodicalId":6895,"journal":{"name":"Acta Crystallographica Section D: Biological Crystallography","volume":"12 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2015-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84894244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Structure of Human Saposin a at Lysosomal Ph.","authors":"C. Hill, R. Read, J. Deane","doi":"10.2210/PDB4UEX/PDB","DOIUrl":"https://doi.org/10.2210/PDB4UEX/PDB","url":null,"abstract":"","PeriodicalId":6895,"journal":{"name":"Acta Crystallographica Section D: Biological Crystallography","volume":"18 1","pages":"895"},"PeriodicalIF":2.2,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83349528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Yoon, Yong-Hak Kim, Nahee Kim, Bo-Young Yun, Jin-Sik Kim, Joon-Hee Lee, Hyun-soo Cho, Kangseok Lee, N. Ha
{"title":"Structure of the periplasmic copper-binding protein CueP from Salmonella enterica serovar Typhimurium. Corrigendum","authors":"B. Yoon, Yong-Hak Kim, Nahee Kim, Bo-Young Yun, Jin-Sik Kim, Joon-Hee Lee, Hyun-soo Cho, Kangseok Lee, N. Ha","doi":"10.1107/S1399004714013613","DOIUrl":"https://doi.org/10.1107/S1399004714013613","url":null,"abstract":"The affiliation of two of the authors of Yoon et al. [(2013). D69, 1867–1875] is corrected.","PeriodicalId":6895,"journal":{"name":"Acta Crystallographica Section D: Biological Crystallography","volume":"78 10 1","pages":"2053-2053"},"PeriodicalIF":2.2,"publicationDate":"2014-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87903742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Small Angle X-Ray and Neutron Scattering from Solutions of Biological Macromolecules.","authors":"L. Chavas","doi":"10.1107/S1399004714005719","DOIUrl":"https://doi.org/10.1107/S1399004714005719","url":null,"abstract":"A review of Small Angle X-Ray and Neutron Scattering from Solutions of Biological Macromolecules by Dmitri I. Svergun, Michel H. J. Koch, Peter A. Timmins and Roland P. May.","PeriodicalId":6895,"journal":{"name":"Acta Crystallographica Section D: Biological Crystallography","volume":"70 1","pages":"1175 - 1176"},"PeriodicalIF":2.2,"publicationDate":"2014-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1107/S1399004714005719","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61948336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Ponomarenko, S. Chatziefthimiou, I. Kurkova, Y. Mokrushina, A. Stepanova, I. Smirnov, E. M. Avakyan, T. Bobik, A. Mamedov, V. Mitkevich, A. Belogurov, O. Fedorova, M. Dubina, A. Golovin, V. Lamzin, A. Friboulet, A. Makarov, M. Wilmanns, A. Gabibov
{"title":"Role of Kappa>Lambda Light-Chain Constant-Domain Switch in the Structure and Functionality of A17 Reactibody","authors":"N. Ponomarenko, S. Chatziefthimiou, I. Kurkova, Y. Mokrushina, A. Stepanova, I. Smirnov, E. M. Avakyan, T. Bobik, A. Mamedov, V. Mitkevich, A. Belogurov, O. Fedorova, M. Dubina, A. Golovin, V. Lamzin, A. Friboulet, A. Makarov, M. Wilmanns, A. Gabibov","doi":"10.2210/PDB3ZL4/PDB","DOIUrl":"https://doi.org/10.2210/PDB3ZL4/PDB","url":null,"abstract":"","PeriodicalId":6895,"journal":{"name":"Acta Crystallographica Section D: Biological Crystallography","volume":"2 1","pages":"708"},"PeriodicalIF":2.2,"publicationDate":"2014-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82378644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Structure-based drug design","authors":"M. Rarey, B. Kramer, Thomas Lengauer","doi":"10.4172/2329-6887.1000E111","DOIUrl":"https://doi.org/10.4172/2329-6887.1000E111","url":null,"abstract":"Volume 1 • Issue 4 • 1000e111 J Pharmacovigilance ISSN: 2329-6887 JP, an open access journal In today’s world where life is fast-paced, public health is a big concern. With the tremendous ongoing development in the field of pharmaceutical drugs, people can find cure for a vast variety of diseases. These modern-day medicines have been proven to be more effective in treating, managing, controlling and preventing the diseases and their reoccurrence. For example, cancer patients, who had a very low rate of survival in 1970’s, can now be treated more efficiently by chemotherapy. At present, the cancer death rate has declined by 20% in comparison to 1990 [1]. However, along with rapid progress in the efficacy of these pharmaceutical medicines, have come long-term undesirable side effects, poor absorption and clearance, multi-drug resistance, excessive toxicities, and adverse reactions of these medicines. Hence, there is a stringent need to get a closer insight into these drugs in terms of their structure and function, their molecular interactions with large biomolecules (protein, nucleic acids) within the cell, so as to design and/or modify the drugs to have improved potency, fewer side effects and selective binding to their biomolecular target.","PeriodicalId":6895,"journal":{"name":"Acta Crystallographica Section D: Biological Crystallography","volume":"1989 1","pages":"379"},"PeriodicalIF":2.2,"publicationDate":"2013-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88758578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Visualizing the Invisible: Imaging Techniques for the Structural Biologist. By Peter B. Moore. Pp. 368. Oxford University Press, 2012. Price £45. ISBN 978-0-19-976709-0.","authors":"P. Paufler","doi":"10.1107/S0907444913001856","DOIUrl":"https://doi.org/10.1107/S0907444913001856","url":null,"abstract":"","PeriodicalId":6895,"journal":{"name":"Acta Crystallographica Section D: Biological Crystallography","volume":"57 1","pages":"924-924"},"PeriodicalIF":2.2,"publicationDate":"2013-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84754975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}