Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry最新文献_第10页

The presence of dolichol in liver supernatant. 肝脏上清液中乙醇的存在。

Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry Pub Date : 1985-01-01 DOI: 10.3891/acta.chem.scand.39b-0072

E L Appelkvist, T Chojnacki, G Dallner

引用次数: 7

Effect of plasticizers on the polyprene distribution in the liver. 增塑剂对肝脏中聚丙烯分布的影响。

Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry Pub Date : 1985-01-01 DOI: 10.3891/acta.chem.scand.39b-0315

C Edlund, A E Ganning, A Elhammer

引用次数: 0

Protected homocysteine peptides as precursors of labelled methionine peptides. Application in preparation of methionine-enkephalin. 保护同型半胱氨酸肽作为标记蛋氨酸肽的前体。在蛋氨酸-脑啡肽制备中的应用。

Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry Pub Date : 1985-01-01 DOI: 10.3891/acta.chem.scand.39b-0157

K Någren, B Långström, U Ragnarsson

{"title":"Protected homocysteine peptides as precursors of labelled methionine peptides. Application in preparation of methionine-enkephalin.","authors":"K Någren, B Långström, U Ragnarsson","doi":"10.3891/acta.chem.scand.39b-0157","DOIUrl":"https://doi.org/10.3891/acta.chem.scand.39b-0157","url":null,"abstract":"A synthetic scheme from N-benzyloxycarbonyl S-benzyl homocysteine peptide benzyl ester, assembled using well-established procedures in solution and purified, to the corresponding free methionine peptide, has been explored preparatively. Deprotection by sodium in liquid ammonia followed by alkylation on sulfur with methyl iodide gave, after purification by semipreparative HPLC, in the case of methionine-enkephalin a pure product in high yield. No evidence from side-reactions on tyrosine could be detected by HPLC. The scheme was primarily designed to be adaptable to the preparation of 11C-labelled methionine-enkephalin and, in particular, to exploit 11C-methyl iodide, now in routine production in our laboratory, in peptide synthesis, thus providing access to 11C-labelled enkephalins with high specific radioactivity for in vivo experiments. Applying 2H-, 3H-, 13C- or 14C-methyl iodide instead, however, this approach should be equally useful for the preparation of the corresponding peptides. Provided overalkylation by methyl iodide and fatal splitting of peptide bonds by the sodium/ammonia reagent can be avoided, the scheme should be applicable also to the synthesis of other methionine-containing peptides.","PeriodicalId":6886,"journal":{"name":"Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry","volume":"39 3","pages":"157-61"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15108654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Stable glucopyranosylpalladium complexes with cis-beta-hydrogen. A six-membered ring metallocycle with an oxygen donor ligand. 与顺式-氢稳定的葡萄糖吡喃钯配合物。含氧配体的六元环金属环

Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry Pub Date : 1985-01-01 DOI: 10.3891/acta.chem.scand.39b-0469

U Hacksell, H T Kalinkoski, D F Barofsky, G D Daves

{"title":"Stable glucopyranosylpalladium complexes with cis-beta-hydrogen. A six-membered ring metallocycle with an oxygen donor ligand.","authors":"U Hacksell, H T Kalinkoski, D F Barofsky, G D Daves","doi":"10.3891/acta.chem.scand.39b-0469","DOIUrl":"https://doi.org/10.3891/acta.chem.scand.39b-0469","url":null,"abstract":"Two stable glucopyranosylpalladium complexes, chloro[1,3-dimethyl-5-(3,4,6-tri-O-acetyl-2-deoxy-alpha-D -arabinohexopyranosyl)-2,4(1H,3H)-pyrimidinedionnato] (triphenylphosphine)-palladium and the corresponding triphenylarsine analog, were studied using fast atom bombardment mass spectrometry, 1H, 13C and 31P nuclear magnetic resonance, UV and IR spectroscopy to establish structures for these complexes. The data obtained indicate that the pyranosyl ring is in a chair conformation in which palladium (C2'), acetoxy (C3' C4') and acetoxymethyl (C5') are equatorial and 1,3-dimethyl-2,4(1H,3H) pyrimidinedion-5-yl (C1') is axial. The palladium(II) ion is encompassed in a six-membered ring metallocycle in which C2' of the glucopyranosyl ring and the oxygen of the C4 carbonyl of the pyrimidinedionyl group occupy adjacent ligand sites. The other two ligand sites on square planar palladium are occupied by triphenylphosphine (or triphenylarsine) cis to C2' and trans to carbonyl oxygen, and chloride trans to C2' and cis to oxygen. This stable metallocycle has three unusual features, a cis-beta-hydrogen, a six-membered Pd-containing ring and an oxygen donor ligand. Its surprising stability is due to conformational barriers to the proper alignment of Pd with pyranosyl ring substituents required for elimination reactions.","PeriodicalId":6886,"journal":{"name":"Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry","volume":"39 6","pages":"469-76"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15173268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Characterization of calcium and phospholipid dependent protein kinase in isolated rat adipocytes. 离体大鼠脂肪细胞中钙和磷脂依赖性蛋白激酶的表征。

Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry Pub Date : 1985-01-01 DOI: 10.3891/acta.chem.scand.39b-0219

G Skoglund, A Hansson, M Ingelman-Sundberg

引用次数: 16

Chemical heterogeneity of heparan sulfate from a human neuroblastoma cell line. 人神经母细胞瘤细胞系硫酸肝素的化学异质性。

Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry Pub Date : 1985-01-01 DOI: 10.3891/acta.chem.scand.39b-0305

L A Fransson, I Hampson, S Kumar, J Gallagher

引用次数: 2

The presence of isoprenoid compounds in human organs. 类异戊二烯类化合物在人体器官中的存在。

Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry Pub Date : 1985-01-01 DOI: 10.3891/acta.chem.scand.39b-0075

O Tollbom

引用次数: 1

Synthesis of adenylyl-(3'----5')-guanosine and some analogues as probes to explore the molecular mechanism of stimulation of influenza virus RNA polymerase. 合成腺苷基-(3'----5')-鸟苷及其类似物作为探针，探讨刺激流感病毒RNA聚合酶的分子机制。

Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry Pub Date : 1985-01-01 DOI: 10.3891/acta.chem.scand.39b-0657

J Heikkilä, S Stridh, B Oberg, J Chattopadhyaya

引用次数: 0

The purity of two commercial hemeproteins. 两种商业血红蛋白的纯度。

Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry Pub Date : 1985-01-01 DOI: 10.3891/acta.chem.scand.39b-0507

K G Paul, P I Ohlson, B Norden, M L Smith

引用次数: 3

Distribution of dolichol in human and rabbit blood. 乙醇在人和兔血液中的分布。

Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry Pub Date : 1985-01-01 DOI: 10.3891/acta.chem.scand.39b-0323

G Elmberger, P Engfeldt

引用次数: 26