中华内科杂志最新文献

{"title":"[Chinese expert consensus on the diagnosis and treatment of adult T-cell leukemia/lymphoma (2024)].","authors":"","doi":"10.3760/cma.j.cn112138-20240918-00586","DOIUrl":"10.3760/cma.j.cn112138-20240918-00586","url":null,"abstract":"<p><p>Adult T-cell leukemia/lymphoma (ATL), a rare and unique proliferative tumor of T lymphocytes, is associated with human T-cell leukemia virus type 1 (HTLV-1) infection. Due to its diverse clinical features, multidrug resistance of malignant cells, frequent opportunistic infection, and poor prognosis, ATL remains a clinical challenge. A unified understanding of ATL is currently lacking, and its diagnosis and treatment are not standardized in China due to the small number of cases. Therefore, to strengthen our understanding of ATL, hematology experts have formulated the \"Chinese expert consensus on the diagnosis and treatment of adult T-cell leukemia/lymphoma (2024)\" based on the latest research progress at home and abroad. This consensus proposes the latest diagnostic and subtype criteria for ATL in China. Furthermore, it briefly describes the infection situation of HTLV-1 in coastal areas of China, the epidemic trends in China, and the latest evidence and recommendations regarding the pathogenesis, clinical manifestations, and treatment strategies, with the aim to standardize the clinical diagnosis and treatment of ATL and ultimately improve the overall survival of patients with ATL.</p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"63 12","pages":"1196-1204"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Guidelines for the diagnosis and management of multiple myeloma in China (2024 revision)].","authors":"","doi":"10.3760/cma.j.cn112138-20240928-00616","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240928-00616","url":null,"abstract":"<p><p>Multiple myeloma (MM), an incurable clonal plasma cell dysplasia, is the second most common hematological malignancy in many countries, mainly developing in the elderly population. With the emergence of novel agents and laboratory methods, the diagnosis and treatment of MM have been significantly improved. In this version of the \"Guidelines for the diagnosis and management of multiple myeloma in China (2024 revision)\", several examination items have been updated in the diagnostic section; the definition of ultra high-risk MM has been proposed in the risk stratification section; for patients with equal or more than second-line relapse, chimeric antigen receptor T cell therapy and a bispecific T-cell engager have been added; and the treatment recommendations have been listed at different levels based on the best available evidence.</p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"63 12","pages":"1186-1195"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Guidelines for the diagnosis and management of multiple myeloma: 2024 updates].","authors":"J Lu","doi":"10.3760/cma.j.cn112138-20241008-00662","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20241008-00662","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"63 12","pages":"1160-1162"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Glucokinase activators: the first step in regulating intracellular glucose metabolism].","authors":"Y Hu, Y J Li, Y M Mu","doi":"10.3760/cma.j.cn112138-20240713-00448","DOIUrl":"10.3760/cma.j.cn112138-20240713-00448","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"63 12","pages":"1170-1174"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Interpretation of risk stratification in guidelines for the diagnosis and management of multiple myeloma in China (2024 revision)].","authors":"S N Chen, L G Qiu","doi":"10.3760/cma.j.cn112138-20241008-00665","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20241008-00665","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"63 12","pages":"1175-1178"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research progress in IgG₄-related disease over the recent decade].","authors":"Y X Nie, W Zhang","doi":"10.3760/cma.j.cn112138-20240924-00602","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240924-00602","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"63 12","pages":"1144-1148"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Expert consensus on multidisciplinary clinical management for chronic kidney disease].","authors":"","doi":"10.3760/cma.j.cn112138-20240910-00566","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240910-00566","url":null,"abstract":"<p><p>Chronic kidney disease (CKD) has been a major public health challenge threatening human health worldwide. When patients with CKD eventually progress to end-stage kidney disease, it imposes a substantial burden on individuals and society. Currently, the diagnosis rate of CKD in China remains low, with an unfavorable status regarding diagnosis and treatment. Therefore, it is urgent to establish a comprehensive prevention and treatment system of CKD, that enhances the multidisciplinary clinical management pathway for CKD patients while improving physicians' co-screening and co-management capabilities across various disciplines for high-risk individuals. Based on current evidence and clinical experience, we formulate the expert consensus on multidisciplinary clinical management approach for CKD, which aims to achieve early detection, early treatment, delay the progression of kidney failure, reduce the risk of cardiovascular, cerebrovascular diseases as well as death in CKD patients, while improving the prognosis of CKD patients and alleviating the burden of CKD disease with a multidisciplinary co-screening co-management model for CKD.</p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"63 12","pages":"1216-1227"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Study on the value of enhanced magnetic resonance imaging in the International Prophylaxis Study Group (IPSG) score of the synovium in hemophilic arthropathy].","authors":"Y X Zhang, S F Wei, F F Zhang, P C Lei, Y H Ge","doi":"10.3760/cma.j.cn112138-20240512-00299","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240512-00299","url":null,"abstract":"<p><p><b>Objective:</b> To evaluate the value of enhanced magnetic resonance imaging (MRI) on the assessment of synovial hyperplasia and International Prophylaxis Study Group (IPSG) score of hemophilic arthropathy (HA). <b>Methods:</b> This was a retrospective case series study. Briefly, 54 joints of 46 male patients with hemophilia type A and diagnosed with HA in Henan Provincial People's Hospital from August 2016 to September 2017 were selected. Plain and enhanced MRI were performed at the same time. The IPSG score of synovial hyperplasia and the total joint before and after enhancement were calculated, and the enhancement rate of the synovium and muscles at the same level were also calculated. The differences in synovial hyperplasia and joint total IPSG scores before and after enhancement were compared by paired rank sum test. The correlation between enhancement joint total IPSG score, synovial IPSG score, synovial enhancement rate, total joint bleeding number, course of disease, and Hemophilia Joint Health Score (HJHS) score were analyzed by Spearman's correlation analysis. <b>Results:</b> Enhanced MRI could more clearly show synovial hyperplasia and ensure better accuracy of joint total IPSG score (<i>Z</i>=-2.24, <i>P</i>=0.025). The enhancement extent of synovial hyperplasia was higher than that of the same level muscle. There was no correlation between synovial enhancement rate and total number of joint bleeding, course of disease, and HJHS score. After enhancement, the joint total IPSG score was highly positively correlated with the total number of joint bleeding and the disease course (<i>r</i>=0.96, 0.84, <i>P</i><0.001) and moderately positively correlated with the HJHS score (<i>r</i>=0.58, <i>P</i><0.001). The enhanced synovial IPSG score showed a low positive correlation with the total number of joint bleeding and the disease course (<i>r</i>=0.37, 0.36, <i>P</i>=0.006, 0.008), but no correlation with HJHS score. <b>Conclusion:</b> Enhanced MRI can provide accurate imaging of synovial hyperplasia of HA and make joint IPSG score more accurate.</p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"63 12","pages":"1246-1251"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[An overlooked risk factor for pan-vascular disease: hyperinsulinemia].","authors":"Y Qian, Q Fu, T Yang","doi":"10.3760/cma.j.cn112138-20240716-00455","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240716-00455","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"63 12","pages":"1163-1169"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Macrophage activation syndrome secondary to systemic sclerosis and systemic lupus erythematosus overlap syndrome: a case report].","authors":"D Ma, Q Wu, J R Cheng, Q R Wu, X Li, Y H Peng","doi":"10.3760/cma.j.cn112138-20240902-00550","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240902-00550","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"63 12","pages":"1257-1260"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}