中华内科杂志最新文献

{"title":"[A case of 11β-hydroxylase deficiency complicated with bilateral adrenal myelolipoma].","authors":"M Lin, Z Z Zhou, Z Y Li, F J Huang, X M Gao, D M Li, H J Zhang","doi":"10.3760/cma.j.cn112138-20240703-00421","DOIUrl":"10.3760/cma.j.cn112138-20240703-00421","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 2","pages":"167-172"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143043767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A case report of hypomagnesemia with secondary hypocalcemia caused by a novel compound heterozygous mutation of the TRPM6 gene].","authors":"Y J Wang, X N Hu, X L Wang, J M Ba, Z H Lyu","doi":"10.3760/cma.j.cn112138-20240701-00415","DOIUrl":"10.3760/cma.j.cn112138-20240701-00415","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"65-68"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143056161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A rare case of PIK3R1 gene mutation associated SHORT syndrome].","authors":"X Zhang, L W H Lin, L Xie, K N Chen, H B Quan","doi":"10.3760/cma.j.cn112138-20240513-00303","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240513-00303","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"60-64"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143056162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Expert opinions on influenza vaccination for patients with common cardiovascular diseases].","authors":"","doi":"10.3760/cma.j.cn112138-20240719-00462","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240719-00462","url":null,"abstract":"<p><p>The influenza virus is classified as a single-stranded negative-sense RNA virus in Orthomyxoviridae family, with epidemiological properties distinct from common cold. Previous studies have found that influenza infection can cause cardiac damage through various pathways, and patients with cardiovascular diseases are at relatively higher risk of adverse disease outcomes. Influenza vaccination has been proven to provide protective effect on patients with cardiovascular diseases. Currently, there is insufficient emphasis placed by cardiologists and cardiovascular disease patients on the prevention of influenza infection, leading to a low influenza vaccination rate in China. Therefore, based on the current clinical research progress and relevant guidelines, combined with the safety, feasibility and health economic benefits of influenza vaccinating in patients with cardiovascular diseases, as well as clinical experience from experts, this article proposes expert opinions on influenza vaccination in common cardiovascular diseases aiming to raise awareness of influenza prevention and benefiting patients.</p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"11-22"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The 510th case: fever of unknown origin, acute kidney injury].","authors":"Y R Shou, Y L Mai, F P Guo, H Zheng, C W Jia, X Y Li, Z Y Liu, T S Li","doi":"10.3760/cma.j.cn112138-20240508-00293","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240508-00293","url":null,"abstract":"<p><p>A 65-year-old male was admitted to Peking Union Medical College Hospital. The patient had intermittent fever for 2 months with a maximum body temperature of 39.3 ℃ and elevated serum creatinine levels for 1 week. He had no other suggestive symptoms or positive signs. Laboratory test results suggested acute kidney injury and a sharp elevation in serum lactic dehydrogenase levels. Abdominal enhanced computed tomography (CT) revealed multiple low-density lesions, and further biopsy pathology demonstrated chronic inflammation. Thereafter, positron emission tomography (PET)/CT showed abnormally elevated uptake value for the bones throughout the entire body, in addition to the liver and brain. Repeated bone marrow biopsy finally confirmed metastatic bone cancer, which possibly originated from the kidney according to immunohistochemical staining. In this rare case of fever of unknown origin, the primary lesion was a renal tumor with bone, liver, and brain metastases. Enhanced CT and PET/CT provided negative results, and the diagnosis was eventually confirmed by repeated bone marrow pathology.</p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"83-87"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analyses of the risk factors of delayed extubation after extended thymectomy in patients with myasthenia gravis].","authors":"M P Wang, X Q Sun, L Jiang, R Lou, Q Si, T T Wang, G J Lu","doi":"10.3760/cma.j.cn112138-20240905-00555","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240905-00555","url":null,"abstract":"<p><p><b>Objective:</b> To explore the risk factors of delayed extubation after expanded thymectomy in patients with myasthenia gravis. <b>Methods:</b> Patients with myasthenia gravis who underwent expanded thymectomy from May 2021 to January 2024 and were admitted to Intensive Care Unit (ICU) after surgery were retrospectively analyzed. Patients were divided in to the delayed extubation and successful extubation according to the length of mechanical ventilation whether exceeding than 48 hours. Multivariable logistics regression was used to explore the risk factors for delayed extubation after expanded thymectomy in patients with myasthenia gravis. <b>Results:</b> A total of 95 patients were included.15 (15.8%) of whom were delayed extubation. Compared with the successful extubation patients, the length of mechanical ventilation (94.0 h vs. 15.5 h, <i>P</i><0.001), ICU station (7.1 days vs. 1.7 days, <i>P</i><0.001), and hospitalization station (16.0 days vs. 9.1 days, <i>P</i><0.001) were significantly prolonged in the delayed extubation patients. Adjusted for age,gender, BMI, clinical classification, pathological classification of thymoma, dose of pyridostigmine preoperative, perioperative pneumonia, preoperative pulmonary dysfunction, SBT passing for the first time, neck lift time greater than 20 seconds, the multivariable logistic regression shown, the risk of delayed extubation increased by 29% (<i>OR</i>=1.290, 95%<i>CI</i> 1.090-1.714), 1% (<i>OR</i>=1.009, 95%<i>CI</i> 1.002-1.034), 3.9-fold (<i>OR</i>=4.977, 95%<i>CI</i> 1.486-10.939), and 64% (<i>OR</i>=1.635, 95%<i>CI</i> 1.396-2.682) for every 60 mg/day increase in preoperative dose of pyridostigmine, pathological classification of thymoma, perioperative pneumonia, and preoperative pulmonary dysfunction, respectively. Neck lift time greater than 20 seconds can reduce the risk of delayed extubation 48% (<i>OR</i>=0.524, 95%<i>CI</i> 0.322-0.794). <b>Conclusion:</b> Preoperative administration of a large dose of pyridostigmine, pulmonary dysfunction, pathological classification of thymoma, and perioperative pneumonia were risk factors for delayed extubation after thymectomy in these patients. And neck lift time greater than 20 seconds decreased the risk of delayed extubation. In the clinical practice,for high risk of MG patients with delayed extubation, the neck lifting test may be used to assess muscle strength and reduce the occurance of tracheal reintubation and its advise effects.</p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"52-59"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Technical standards for performing radiofrequency catheter ablation for atrial fibrillation: a series of consortium standards].","authors":"","doi":"10.3760/cma.j.cn112138-20240907-00559","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240907-00559","url":null,"abstract":"<p><p>Atrial fibrillation (AF) has emerged as a major global cardiovascular disease in the 21st century. In China, there are greater than 12 million patients with AF, and its incidence continues to rise. AF affects patients' quality of life and significantly increases the risks of mortality, stroke, heart failure, cognitive impairment, and dementia. In recent years, multiple clinical guidelines have expanded the indications for catheter ablation and raised its level of recommendation. Concurrently, there has been a rapid and sustained increase in the number of AF ablation procedures performed across China. Among these, radiofrequency catheter ablation remains the most used method. Consequently, the Chinese Heart Rhythm Society of the Chinese Society of Biomedical Engineering, in collaboration with 40 arrhythmia centers and 60 leading clinical experts specializing in AF catheter ablation, developed a comprehensive set of standards. These standards were developed based on extensive clinical experience accumulated in recent years and the latest national and international AF guidelines and consensus documents. They address five critical domains: periprocedural management, intra-atrial septal puncture, anatomical reconstruction and electroanatomic mapping, ablation, and complication identification and management. By providing a structured framework, these standards aim to guide AF catheter ablation practice, thereby enhancing procedural safety and efficacy.</p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"23-35"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The diagnosis and treatment of chimeric antigen receptor T-cell associated hemophagocytic lymphohistiocytosis].","authors":"J L Hu, C C Feng, L B He, Y N Wang","doi":"10.3760/cma.j.cn112138-20240506-00284","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240506-00284","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"77-82"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The impact of frailty on the prognosis of chronic heart failure patients treated with cardiac resynchronization therapy defibrillator implantation].","authors":"L Gao, H S Lyu, B P Tang, X H Zhou, X C Cheng, Y Q Shi, Y D Li, J H Zhang, Q Xing, Tuerhong Zukela, Y M Lu","doi":"10.3760/cma.j.cn112138-20240827-00537","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240827-00537","url":null,"abstract":"<p><p><b>Objective:</b> The aim of this study was to assess the frailty status of patients with heart failure undergoing CRT-D and then explore the predictive value of frailty for all-cause mortality and heart failure-related readmissions in these patients. <b>Methods:</b> We retrospectively included 374 patients with chronic heart failure who underwent CRT-D treatment at the First Affiliated Hospital of Xinjiang Medical University between June 2020 and June 2024. Based on the Tilburg Debilitation Assessment Scale, 175 patients (46.8%) were classified as frail while 199 (53.2%) were classified as non-frail. The baseline data between the two groups was compared using Cox regression analysis and Kaplan-Meier curves were used for survival analysis. <i>P</i>-values of <0.05 indicated statistically significant differences. <b>Results:</b> A total of 374 patients aged 25-93 (68±11) years were enrolled in this study, 101 (27.0%) of which were female. Among these, 175 (46.8%) were categorized as frail, and 199 (53.2%) were classified as non-frail. Over a median follow-up time of 23 (5, 45) months, 35 (9.4%) patients experienced all-cause mortality, with 30 (17.1%) deaths occurring in the frail group and 5 (2.5%) in the non-frail group; meanwhile, readmission events due to heart failure occurred in a total of 174 (46.5%) patients, including 122 (70.1%) in the frail group, and 52 (29.9%) in the non-frail group. Cox analysis showed that frailty was a significant determinant of all-cause mortality (<i>HR</i>=21.25, 95%<i>CI</i> 3.99-113.30, <i>P</i><0.001) and readmission among heart failure patients receiving CRT-D (<i>HR</i>=2.52, 95%<i>CI</i> 1.73-3.68, <i>P</i><0.001). Log-rank tests showed that the survival rate of patients in the frail group was significantly lower than that of patients in the non-frail group (<i>HR</i>=7.22, 95%<i>CI</i> 2.80-18.60, <i>P</i><0.001) and the risk of readmission events due to heart failure was significantly higher among patients in the frail group than among those in the non-frail group (<i>HR</i>=2.75, 95%<i>CI</i> 1.98-3.81, <i>P</i><0.001). <b>Conclusions:</b> Frailty is an independent predictor of postoperative all-cause mortality and the occurrence of heart failure-related readmissions in patients with heart failure treated receiving CRT-D.</p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"45-51"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Interpretation of the transparent reporting of a multivariable prediction model for individual prognosis or diagnosis based on regression or machine learning methods (TRIPOD+AI)].","authors":"M H Yan, Y Y Zhao, X Liu, W Li, Y Wang","doi":"10.3760/cma.j.cn112138-20240926-00609","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240926-00609","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"4-10"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}