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2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)最新文献

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Computer modeling of stress-strain state of the intact portion of the coronary artery with circular irregular stenosis 环形不规则狭窄冠状动脉完整部分应力-应变状态的计算机模拟
2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON) Pub Date : 2015-12-28 DOI: 10.1109/SIBIRCON.2015.7361877
P. Alexey, V. Alexey
{"title":"Computer modeling of stress-strain state of the intact portion of the coronary artery with circular irregular stenosis","authors":"P. Alexey, V. Alexey","doi":"10.1109/SIBIRCON.2015.7361877","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361877","url":null,"abstract":"According to the world health organization, diseases of the cardiovascular system occupy a leading place among the pathologies on disability and mortality in developed countries, and the defeat of coronary arteries, in turn, leads to coronary heart disease. The simulation of condition and parameters of coronary arteries with atherosclerotic lesions is an actual problem of modern biomechanics. The aim of the present work was to study the stress-strain state of the intact portion of the coronary artery with uniform circular stenosis. 3D computer modeling of the stress - strain state of the intact portion of the coronary artery with a circular irregular stenosis, the study of its mechanical parameters in accordance with the load on it with the atherosclerotic plaque and during stenting was performed. Comparative analysis of the influence of boundary conditions fixing the coronary arteries relative to the epicardium and geometric characteristics of the stenosis on the basic mechanical parameters of the stress-strain state of an artery was realized. The results of this analysis allow to minimize the dimension of the input data that affect the computer simulation. The results of study suggest of the necessity of development and creation of expert decision support system for interventional cardiologist in the field of stent size selection and balloon blowup pressure to reduce the traumatization of the endothelial vessel's layer during the operation, as well as reducing the duration of the procedure.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"77 1","pages":"176-179"},"PeriodicalIF":0.0,"publicationDate":"2015-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74062121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiplex detection of IgG class antibodies to Toxoplasma gondii, Rubella virus, Cytomegalovirus and Herpes virus using a novel multiplex flow immunoassay 用一种新的多重流免疫分析法检测刚地弓形虫、风疹病毒、巨细胞病毒和疱疹病毒IgG类抗体
2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON) Pub Date : 2015-12-28 DOI: 10.1109/SIBIRCON.2015.7361850
S. Dolgushin, S. Selishchev, E. Loseva, E. Odintsova, A. Tronin
{"title":"Multiplex detection of IgG class antibodies to Toxoplasma gondii, Rubella virus, Cytomegalovirus and Herpes virus using a novel multiplex flow immunoassay","authors":"S. Dolgushin, S. Selishchev, E. Loseva, E. Odintsova, A. Tronin","doi":"10.1109/SIBIRCON.2015.7361850","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361850","url":null,"abstract":"Preclinical tests of a novel multiplex immunoassay for the detection of TORCH infections in human serum using flow cytometry are presented. The immunoassay is intended for the qualitative detection of specific human IgG class antibodies to Toxoplasma gondii, Rubella virus Cytomegalovirus and Herpes virus in human serum. Multiplex analysis is performed in vitro on polystyrene microspheres encoded with organic dye. The diagnostic sensitivity of the kit is evaluated to be not less than 95%.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"27 1","pages":"57-58"},"PeriodicalIF":0.0,"publicationDate":"2015-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77471652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Development of microbicide equipment and research in pathogen inactivation by cold argon plasma 杀微生物设备的研制及冷氩等离子体灭活病原体的研究
2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON) Pub Date : 2015-12-28 DOI: 10.1109/SIBIRCON.2015.7361853
A. Semyonov, B. Baldanov, Ts. V. Ranzhurov, E. Nikolayev, S. Gomboyeva
{"title":"Development of microbicide equipment and research in pathogen inactivation by cold argon plasma","authors":"A. Semyonov, B. Baldanov, Ts. V. Ranzhurov, E. Nikolayev, S. Gomboyeva","doi":"10.1109/SIBIRCON.2015.7361853","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361853","url":null,"abstract":"The high bactericidal effect of cold argon plasma generated by low-current spark discharge plasma jets at atmospheric pressure has been presented. It has been found that the direct contact of low-current spark plasma jets helps perform effective inactivation of bacteria.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"114 1","pages":"68-71"},"PeriodicalIF":0.0,"publicationDate":"2015-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77735923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic nanoprobes based on the conjugates of quantum dots and single-domain antibodies for cancer biomarkers detection in immunohistochemistry and flow cytometry 基于量子点和单域抗体偶联物的诊断纳米探针在免疫组织化学和流式细胞术中检测癌症生物标志物
2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON) Pub Date : 2015-12-28 DOI: 10.1109/SIBIRCON.2015.7361863
A. Sukhanova, J. Millot, M. Pluot, J. Cohen, I. Nabiev
{"title":"Diagnostic nanoprobes based on the conjugates of quantum dots and single-domain antibodies for cancer biomarkers detection in immunohistochemistry and flow cytometry","authors":"A. Sukhanova, J. Millot, M. Pluot, J. Cohen, I. Nabiev","doi":"10.1109/SIBIRCON.2015.7361863","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361863","url":null,"abstract":"Monoclonal antibodies (mAbs) are often too big for the nanoparticle targeting purpose and the conditions used for their conjugation provide nanoprobes with irregular orientation of mAbs on the surface of nanoparticle. Here, we are reviewing our recent publications reporting on ultra-small nanoprobes engineered through oriented conjugation of quantum dots (QDs) with 13-kDa single-domain antibodies (sdAbs) derived from llama and produced in E. coli. Developed nanoprobes with hydrodynamic diameter below 12 nm contain four homogeneously oriented copies of sdAbs on the surface of each QD. They demonstrated excellent specificity and sensitivity for the quantitative detection of rare biomarker-expressing cells using flow cytometry. The higher diffusibility of sdAbs enables immunohistochemical analysis of thick tissues not accessible to mAbs. The data shows that sdAbs-QD conjugates lead to biopsy tissue labelling displaying an equivalent or even better quality than that obtained with gold standard immunohistochemical diagnostics. Developed sdAbs-QD nanoprobes should find numerous applications in multiplexed high-throughput diagnostics and FRET-based detection platforms.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"37 1","pages":"113-118"},"PeriodicalIF":0.0,"publicationDate":"2015-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79526114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Patient-specific 1D model of the human cardiovascular system 人体心血管系统患者特异性1D模型
2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON) Pub Date : 2015-12-28 DOI: 10.1109/SIBIRCON.2015.7361855
I. Kiselev, F. Kolpakov, E. Biberdorf, V. Baranov, T. G. Komlyagina, I. Suvorova, V. Melnikov, S. Krivoschekov
{"title":"Patient-specific 1D model of the human cardiovascular system","authors":"I. Kiselev, F. Kolpakov, E. Biberdorf, V. Baranov, T. G. Komlyagina, I. Suvorova, V. Melnikov, S. Krivoschekov","doi":"10.1109/SIBIRCON.2015.7361855","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361855","url":null,"abstract":"A technique of parameter personalization of a 1d hemodynamic model is discussed and validated against physiological data of 1546 examined patients. Different parameter combinations were used, with the quality of prediction of the systolic and diastolic pressures used as the principle validation criterion. It is shown that with an appropriate personalization the model can provide adequate predictions (correlations near 0.9), where the decisive role is played by the total peripheral resistance parameter. Meanwhile parameters of the largest arteries do not play a significant role in the prediction.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"5 1","pages":"76-81"},"PeriodicalIF":0.0,"publicationDate":"2015-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84186893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Digraph based medical treatment planning 基于有向图的医疗计划
2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON) Pub Date : 2015-12-28 DOI: 10.1109/SIBIRCON.2015.7361876
M. Levin
{"title":"Digraph based medical treatment planning","authors":"M. Levin","doi":"10.1109/SIBIRCON.2015.7361876","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361876","url":null,"abstract":"The paper focuses on framework of combinatorial planning for medical treatment on the basis of digraph with three-component vertices (analysis/diagnosis, de-sign/implementation, analysis/decision). A generalized medical treatment plan is considered as a route/trajectory over the digraph. The set of used underlying problems involves: (a) multicriteria analysis/diagnosis, (b) multicriteria selection/design, (c) selection of the treatment direction. Combinatorial synthesis based on morphological clique is used (i.e., Hierarchical Morphological Design). An illustrative numerical example corresponds to children asthma.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"29 1","pages":"171-175"},"PeriodicalIF":0.0,"publicationDate":"2015-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72842441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The potential of lasing in quantum dots for sensing and diagnostic applications 量子点激光在传感和诊断应用中的潜力
2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON) Pub Date : 2015-12-28 DOI: 10.1109/SIBIRCON.2015.7361865
S. Dayneko, I. Nabiev
{"title":"The potential of lasing in quantum dots for sensing and diagnostic applications","authors":"S. Dayneko, I. Nabiev","doi":"10.1109/SIBIRCON.2015.7361865","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361865","url":null,"abstract":"Sensing with semiconductor colloidal quantum dots (QDs) is driven by attractive properties of these fluorophores such as spectrally narrow and tunable emission and broad absorption spectra, which enable simultaneous excitation of fluorescence of different colors. The possibility of lasing upon inclusion of QDs into microcavities offers new opportunities for highly sensitive sensing. Here, we discuss the fundamental properties of QDs, the principles of lasing from QDs, and potential applications of the effect of QD lasing to diagnostics and ultrasensitive sensing.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"117 1","pages":"122-123"},"PeriodicalIF":0.0,"publicationDate":"2015-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86800027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Linguistic view on brain-computer interface 脑机接口的语言学观点
2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON) Pub Date : 2015-12-28 DOI: 10.1109/SIBIRCON.2015.7361839
Mariya K. Timofeeva
{"title":"Linguistic view on brain-computer interface","authors":"Mariya K. Timofeeva","doi":"10.1109/SIBIRCON.2015.7361839","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361839","url":null,"abstract":"Being a sort of communication, Brain-Computer Interface (BCI) uses a language, and therefore can be an object of linguistic consideration. This fact gives rise to two questions. What analogies can be found between BCI and linguistic approaches, methods, experience; what hypothesis about applicability of linguistics to BCI can be proposed? What challenges for linguistics can result from prospective development of BCI? The paper considers both issues. For the first it draws parallels between BCI (particularly training the BCI skill) and field linguistics. For the second the paper considers challenges connected with general and semantic linguistic issues.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"41 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2015-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91220638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of electron-beam irradiation on electrospinning produced scaffolds 电子束辐照对静电纺丝制备支架的影响
2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON) Pub Date : 2015-12-28 DOI: 10.1109/SIBIRCON.2015.7361846
A. Stepanova, M. V. Korobeinikov, A. S. Yunoshev, P. Laktionov
{"title":"Effect of electron-beam irradiation on electrospinning produced scaffolds","authors":"A. Stepanova, M. V. Korobeinikov, A. S. Yunoshev, P. Laktionov","doi":"10.1109/SIBIRCON.2015.7361846","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361846","url":null,"abstract":"The influence of electron beam irradiation on the stiffness, stability and biocompatibility of electrospun scaffolds, produced from Nylon 6, polycaprolactone (PCL) and poly(DL-lactic-co-glicolic acid) (PLGA) was investigated. It was shown that irradiation of the matrices with an electron beam generated by the electron beam accelerator ILA-6 (2.2 MeV, 400 mA 10 Hz, “Radiochemical technologies Ltd”) can potentially be used for sterilization of the matrices (irradiation by a dose of 25 kGy does not interfere with the mechanical properties of all studied matrices). Irradiation of the matrices produced from PCL by a dose of 100 kGy increases the proportional limit of the material and allowed us to introduce durable regions into the vascular grafts by irradiating the graft through the template with open areas. Electron beam irradiation of the matrices does not interfere with the capacity of the matrices to support adhesion and viability of primary human endotheliocytes at the surfaces of these matrices, as it was shown using Alamar Blue assay.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"34 1","pages":"39-42"},"PeriodicalIF":0.0,"publicationDate":"2015-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79028161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Microcubes aided photonic jet scalpel tips for potential use in ultraprecise laser surgery 微立方体辅助光子射流手术刀尖端在超精密激光手术中的潜在应用
2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON) Pub Date : 2015-12-28 DOI: 10.1109/SIBIRCON.2015.7361842
O. Minin, I. Minin, Nikita A. Kharitoshin
{"title":"Microcubes aided photonic jet scalpel tips for potential use in ultraprecise laser surgery","authors":"O. Minin, I. Minin, Nikita A. Kharitoshin","doi":"10.1109/SIBIRCON.2015.7361842","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361842","url":null,"abstract":"The task of development of compact light-focusing tools for biomedical applications is challenging due to subwavelength focusing in such devices. In this study we have shown that it is possible to focusing light beyond the diffraction limit by 3D mesoscale particles in application to laser scalpel tips for potential use in ultraprecise laser surgery. The focusing properties as a single as a chain of cubic particles including metamaterials are discussed to form ultraprecise subdiffraction area both axisymmetrical and curvelinear (photonic hook scalpel).","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"35 1","pages":"18-21"},"PeriodicalIF":0.0,"publicationDate":"2015-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81401752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
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