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Research Progress in the Preparation of 13C-Methacetin 13C-Methacetin的制备研究进展
药物化学 Pub Date : 2023-01-01 DOI: 10.12677/hjmce.2023.111005
国桢 付
{"title":"Research Progress in the Preparation of 13C-Methacetin","authors":"国桢 付","doi":"10.12677/hjmce.2023.111005","DOIUrl":"https://doi.org/10.12677/hjmce.2023.111005","url":null,"abstract":"","PeriodicalId":64647,"journal":{"name":"药物化学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66077494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research Progress on Histone Deacetylase Inhibitors 组蛋白去乙酰化酶抑制剂的研究进展
药物化学 Pub Date : 2023-01-01 DOI: 10.12677/hjmce.2023.112015
玉姜 汤
{"title":"Research Progress on Histone Deacetylase Inhibitors","authors":"玉姜 汤","doi":"10.12677/hjmce.2023.112015","DOIUrl":"https://doi.org/10.12677/hjmce.2023.112015","url":null,"abstract":"","PeriodicalId":64647,"journal":{"name":"药物化学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66078133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study on the Chemical Constituents from Hypericum lancasteri and Their Antioxidant Activities 兰开斯特金丝桃化学成分及其抗氧化活性研究
药物化学 Pub Date : 2023-01-01 DOI: 10.12677/hjmce.2023.113021
潘潘 张
{"title":"Study on the Chemical Constituents from Hypericum lancasteri and Their Antioxidant Activities","authors":"潘潘 张","doi":"10.12677/hjmce.2023.113021","DOIUrl":"https://doi.org/10.12677/hjmce.2023.113021","url":null,"abstract":"Objective: To isolate and identify the chemical composition of Hypericum lancasteri N. Robson; eva-*","PeriodicalId":64647,"journal":{"name":"药物化学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66078372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research Progress of Traditional Chinese Medicine Fermented by Intestinal Flora 中药肠道菌群发酵研究进展
药物化学 Pub Date : 2023-01-01 DOI: 10.12677/hjmce.2023.114027
西亚 罗
{"title":"Research Progress of Traditional Chinese Medicine Fermented by Intestinal Flora","authors":"西亚 罗","doi":"10.12677/hjmce.2023.114027","DOIUrl":"https://doi.org/10.12677/hjmce.2023.114027","url":null,"abstract":"With its unique advantages, traditional Chinese medicine fermentation technology has been passed on from ancient times to the present. Modern fermentation technology is closely combined with microbiology, bioengineering, genetics and other disciplines, which makes the fermentation mechanism mature gradually. The synergistic and attenuating effect of traditional Chinese medicine fermentation is more obvious, which greatly improves the quality of traditional Chinese medicine fermentation. The selection of suitable strain fermentation is the core and premise, and it is also the main problem faced by this technology. Intestinal flora is in line with the complexity, natural and scientific nature of traditional Chinese medicine fermentation compound bacteria. A large number of studies have confirmed that traditional Chinese medicine can interact with intestinal flora after oral administration, and then play the role of increasing efficiency and reducing toxicity and maintaining the homeostasis of the body. Based on the research status of traditional Chinese medicine fermentation and the advantages of intestinal flora fermentation of traditional Chinese medicine, this paper puts forward the concept of traditional Chinese medicine fermented by intestinal flora in vitro , and looks forward to the problems faced by this concept.","PeriodicalId":64647,"journal":{"name":"药物化学","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135508313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid Quality Evaluation of the Concentrated Liquid of Liuwei Dihuang Pills by Near-Infrared Spectroscopy 近红外光谱快速评价六味地黄丸浓缩液的质量
药物化学 Pub Date : 2023-01-01 DOI: 10.12677/hjmce.2023.111001
静 常
{"title":"Rapid Quality Evaluation of the Concentrated Liquid of Liuwei Dihuang Pills by Near-Infrared Spectroscopy","authors":"静 常","doi":"10.12677/hjmce.2023.111001","DOIUrl":"https://doi.org/10.12677/hjmce.2023.111001","url":null,"abstract":"","PeriodicalId":64647,"journal":{"name":"药物化学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66077653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of Acetylated Ursolic Acid Catalyzed by Phosphotungstic Acid 磷钨酸催化合成乙酰化熊果酸
药物化学 Pub Date : 2023-01-01 DOI: 10.12677/hjmce.2023.111002
玉丽 郑
{"title":"Synthesis of Acetylated Ursolic Acid Catalyzed by Phosphotungstic Acid","authors":"玉丽 郑","doi":"10.12677/hjmce.2023.111002","DOIUrl":"https://doi.org/10.12677/hjmce.2023.111002","url":null,"abstract":"","PeriodicalId":64647,"journal":{"name":"药物化学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66077688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Technology Optimization of Removing Ginkgolic Acid from Ginkgo biloba by Ultrasound Assisting Alkaline Solution 超声辅助碱性溶液脱除银杏中银杏酸的工艺优化
药物化学 Pub Date : 2023-01-01 DOI: 10.12677/hjmce.2023.114029
君豪 龚
{"title":"Technology Optimization of Removing Ginkgolic Acid from Ginkgo biloba by Ultrasound Assisting Alkaline Solution","authors":"君豪 龚","doi":"10.12677/hjmce.2023.114029","DOIUrl":"https://doi.org/10.12677/hjmce.2023.114029","url":null,"abstract":"In this paper, fixed power ultrasound assisting alkaline solution was used to reduce the content of ginkgolic acid in Ginkgo biloba and establish a new process for reducing the allergenic substances","PeriodicalId":64647,"journal":{"name":"药物化学","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135661328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role and Future Directions of PI3K Inhibitors in Cancer Treatment PI3K抑制剂在癌症治疗中的作用及未来发展方向
药物化学 Pub Date : 2023-01-01 DOI: 10.12677/hjmce.2023.112013
思远 郝
{"title":"Role and Future Directions of PI3K Inhibitors in Cancer Treatment","authors":"思远 郝","doi":"10.12677/hjmce.2023.112013","DOIUrl":"https://doi.org/10.12677/hjmce.2023.112013","url":null,"abstract":"The phosphoinositol 3 kinase (PI3K)-protein kinase B (PKB/AKT) mammalian rapamycin target protein (mTOR) axis is a key signal transduction system that connects oncogenes and multiple receptor categories, participating in many important cellular functions. The abnormal PI3K signaling pathway is one of the most common mutation pathways in cancer. Due to the fact that carcino-*","PeriodicalId":64647,"journal":{"name":"药物化学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66077844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study on the Elution Process of Ginkgo Folium Polyamide Based on MSPC 基于MSPC的银杏叶聚酰胺洗脱工艺研究
药物化学 Pub Date : 2023-01-01 DOI: 10.12677/hjmce.2023.112014
钧 王
{"title":"Study on the Elution Process of Ginkgo Folium Polyamide Based on MSPC","authors":"钧 王","doi":"10.12677/hjmce.2023.112014","DOIUrl":"https://doi.org/10.12677/hjmce.2023.112014","url":null,"abstract":"Objective: In this paper, by establishing the polyamide chromatography elution process trajectory of ginkgo folium crude extract, the whole online monitoring of the elution process is realized, and","PeriodicalId":64647,"journal":{"name":"药物化学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66077962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanism of Cephalophyllum cephalus Intervention in Diabetes Based on Network Pharmacology and Molecular Docking Technology 基于网络药理学和分子对接技术的头叶草干预糖尿病的机制研究
药物化学 Pub Date : 2023-01-01 DOI: 10.12677/hjmce.2023.112011
志梁 范
{"title":"Mechanism of Cephalophyllum cephalus Intervention in Diabetes Based on Network Pharmacology and Molecular Docking Technology","authors":"志梁 范","doi":"10.12677/hjmce.2023.112011","DOIUrl":"https://doi.org/10.12677/hjmce.2023.112011","url":null,"abstract":"","PeriodicalId":64647,"journal":{"name":"药物化学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66078178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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