David Baek, O. Oralkan, M. Kupnik, M. Willatzen, B. Khuri-Yakub, J. Jensen
{"title":"Simulating capacitive micromachined ultrasonic transducers (CMUTs) using field II","authors":"David Baek, O. Oralkan, M. Kupnik, M. Willatzen, B. Khuri-Yakub, J. Jensen","doi":"10.1109/ULTSYM.2010.5935580","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935580","url":null,"abstract":"Field II has been a recognized simulation tool for piezoceramic medical transducer arrays for more than a decade. The program has its strength in doing fast computations of the spatial impulse response (SIR) from array elements by dividing the elements into smaller mathematical elements (ME)s from which it calculates the SIR responses. The program features predefined models for classical transducer geometries, but currently none for the fast advancing CMUTs. This work addresses the assumptions required for modeling CMUTs with Field II. It is shown that rectangular array elements, populated with cells, can be well approximated by neglecting the cells. Further, it is demonstrated that scaling of the SIR translates into better computational efficiency.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75347031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Duy, Brian E. Hackett, Sasha Alcott, T. Mlsna, J. Vetelino, D. Neivandt
{"title":"Detection of peroxide based explosives utilizing a lateral field excited acoustic wave sensor","authors":"W. Duy, Brian E. Hackett, Sasha Alcott, T. Mlsna, J. Vetelino, D. Neivandt","doi":"10.1109/ULTSYM.2010.5935823","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935823","url":null,"abstract":"Due to extensive use of Peroxide Based Explosives (PBEs) in terrorist and insurgent activities, the need for a rapid and accurate sensor is paramount. PBEs can be prepared from items found ubiquitously such as acetone and hydrogen peroxide. Current tests to detect PBEs typically require swabbing of suspected items, which is time consuming and may not be remotely deployed. The results of such tests are qualitative in nature and false positives are common. A need exists for a sensor that can detect PBE constituents in air. The current work is investigating the utility of employing the Lateral Field Excited (LFE) acoustic wave sensor platform for PBE detection. Specifically, a polymer film that is sensitive to both acetone and hydrogen peroxide vapor has been deposited on an LFE platform. The resulting sensor has been demonstrated to be capable of identifying ppm concentrations of the PBE constituent vapors in air.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74930929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. François, G. Martin, P. Grosclaude, M. Lamothe, G. Goavec-Mérou, S. Ballandras, J. Friedt
{"title":"Fabrication and characterization of a SAW-oscillator-based sensing system including an integrated reciprocal counter and a wireless ZigBee transmission system","authors":"B. François, G. Martin, P. Grosclaude, M. Lamothe, G. Goavec-Mérou, S. Ballandras, J. Friedt","doi":"10.1109/ULTSYM.2010.5935999","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935999","url":null,"abstract":"We focus here on the optimization of a sensing system based on SAW resonators inserted in an oscillation loop for very high accuracy measurements. We use single-port SAW resonators built on AT Quartz, inserted in a Colpitts oscillator loop operating near 434 MHz. A reciprocal counter then is implemented on a FPGA platform which communicates the counting result to the ZigBee transmission system using an IEEE 802.15.4 protocol at 2.4 GHz. This system was tested by measuring the temperature of a climatic oven, revealing a measurement accuracy of a couple of 10 μK.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75294117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Front-end implications to multi-standard cellular radios: State-of-the-art and future trends","authors":"R. Vazny, H. Pretl, L. Maurer, R. Weigel","doi":"10.1109/ULTSYM.2010.5935487","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935487","url":null,"abstract":"The present work discusses the implications to the RF front-end for multi-standard multi-band cellular radios by analyzing noise and linearity specifications of the active circuits as well as isolation and insertion loss limits of the involved passive elements. Optimal adjustments of pertinent trade-offs and an outlook into future requirements and trends are presented.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75319461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Realtime control of multiple-focus phased array heating patterns based on noninvasive ultrasound thermography","authors":"A. Casper, Dalong Liu, E. Ebbini","doi":"10.1109/ULTSYM.2010.5935977","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935977","url":null,"abstract":"We present results from realtime feedback control of single- and multiple-focus phased array heating patterns based on ultrasound thermography. The results illustrate several important aspects of realtime control of phased array heating patterns as they are envisioned to be used in noninvasive, image-guided thermal therapy applications. First, complex, multiple-focus heating patterns require multi-point, noninvasive temperature feedback that may not be easily available using thermocouple or other invasive proibes. Second, multiple-focus pattern synthesis must be optimized to maintain the highest efficiency of the phased array driver in order to achieve the control objectives. This has led to the development of a dynamic power reallocation algorithm for realtime management of the power share of each focus accoring to maximize its heating rate. Third, realtime integration between the feedback thermography and array driver control with high spatial and temporal resolution is necessary, especially for short exposures used in ablative treatments. These aspects are well illustrated by the results shown: 1) realtime thermography at frame rates up to 100 fps, 2) realtime multiple-focus pattern resynthesis with update rates up to 1000 patterns per second, and 3) an intelligent dynamic power reallocation scheme to distribute the available driving power according to the collective needs of the individual foci in the multiple-focus heating patterns. Without this dynamic power reallocation, the standard multiple-focus pattern synthesis may produce low-efficiency driving patterns that may fail to achieve the control objective at the some or all control points in the heating pattern.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74759352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Tsujino, T. Yokozuka, Shinnichiro Suga, E. Sugimoto
{"title":"Welding characteristics of bi-metal, braided wires, aluminum and copper foils using 20 kHz ultrasonic complex vibration welding equipments","authors":"J. Tsujino, T. Yokozuka, Shinnichiro Suga, E. Sugimoto","doi":"10.1109/ULTSYM.2010.5935892","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935892","url":null,"abstract":"Welding characteristics of copper, bimetalic strip, braided flexible copper and tin coated copper wires consisted of thin wire elements, and large number of aluminum and copper thin foils are studied. Welding of copper, bimetal and braided wires and different metal foils are required for various electronic devices and multi-layer fuel cell, battery or EDLC electrodes for electric or hybrid automobile and various industry fields. These specimens are welded successfully using complex vibration welding.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73181206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reshu Saini, J. Warram, A. Sorace, H. Umphrey, K. Zinn, K. Hoyt
{"title":"Validation of controlled receptor expression using adenoviral techniques and targeted ultrasound imaging","authors":"Reshu Saini, J. Warram, A. Sorace, H. Umphrey, K. Zinn, K. Hoyt","doi":"10.1109/ULTSYM.2010.5935763","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935763","url":null,"abstract":"This paper details a model system for evaluating targeted ultrasound (US) contrast agents using adenoviral (Ad) vectors for controlled receptor expression. Breast cancer cell receptor density in vitro was modulated by varying the multiplicity of infection (MOI) from 0 to 100. Target receptors were induced using a GFP-positive Ad vector for gene transfer and expression of the human somatostatin receptor subtype 2a (hSSTr2) with a hemagglutinin (HA) tag. Subsequently, receptor expression and anti-HA antibody (Ab) binding was examined with flow cytometry. Targeted US contrast agents (MB) were created by conjugating either biotinylated anti-HA or isotype control Ab to the surface of biotin coated MBs via a streptavidin bridge. Targeted MBs were incubated with Ad infected cells with to test in vitro MB binding. An in vivo study was performed in tumor-bearing nude athymic mice with induced HA-hSSTr2-GFP receptor expression by intratumoral injection of the Ad vector (MOI of 100). Mice were sorted and injected via the tail vein with the two MB groups followed by US imaging. 24 hrs later mice groups were switched and the MB study repeated. Experimental in vitro results found GFP expression to be directly correlated with Ad MOI (R2 = 0.96). Increasing the Ad MOI produced a corresponding increase in binding and accumulation of anti-HA Ab on the cell surface (P < 0.01). However, no differences was found between Cy5.5-labeled anti-HA Ab exposed cell groups at an MOI of 0 (P > 0.29) or in the control Ab group (P > 0.44) indicating minimal nonspecific binding. No difference was found between cells groups incubated with control MBs (P > 0.42) regardless of receptor density. However, cells exposed to targeted MBs showed increased levels of cell binding proportional to receptor expression levels (P < 0.02). Images taken from in vivo experiments were analyzed by two blinded reviewers in consensus to compare intratumoral MB accumulation. It was concluded that 78% (7 of 9) of US images from the targeted MB group exhibited increased local intratumoral accumulation compared to the control group. Overall, this study demonstrates use of an Ad vector for selectively controlling cellular expression and modulation of the receptor density. Furthermore, results demonstrate targeted MB accumulation at the receptor site.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74260162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of low intensity CW ultrasound on acoustic responses of microbubbles generated from phase change nano droplet","authors":"K. Kawabata, R. Asami, T. Azuma, S. Umemura","doi":"10.1109/ULTSYM.2010.5935683","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935683","url":null,"abstract":"Sustaining of microbubbles generated from a phase-change nano-droplet (PCND) was demonstrated by using low intensity ultrasound aiming at precisely targeted ultrasound therapy. PCND, a droplet containing superheated perfluorocarbon, dispersed in polyacrylamide gel was exposed to 1.1-MHz ultrasound pulses at 1.2 kW/cm2 with 100 cycles. The resulting microbubbles were further exposed to very low intensity continuous wave (CW) or burst ultrasound to sustain the bubbles. When CW exposure was used for the sustaining procedure, only fundamental components were observed from the PCND at acoustic intensities around 100 mW/cm2. This suggests the fundamental signal was emitted from the sustained microbubbles because further exposure of 100 W/cm2 ultrasound following the sustaining ultrasound resulted in the generation of fractional harmonics, suggesting the induction of cavitation, while no harmonic components were observed in the absence of the sustaining ultrasound. It was possible to use pulsed ultrasound for the sustaining procedure, when the interval between each pulse was within 10 ms. The time constant was about the same as the lifetime of the microbubbles induced from the PCND in the absence of the sustaining ultrasound. The obtained results are promising for controlling the sensitivity of local sites to therapeutic ultrasound by using PCND and low intensity ultrasound","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74498485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Sherrit, X. Bao, M. Badescu, Y. Bar-Cohen, P. Allen
{"title":"Monolithic rapid prototype flexured ultrasonic horns","authors":"S. Sherrit, X. Bao, M. Badescu, Y. Bar-Cohen, P. Allen","doi":"10.1109/ULTSYM.2010.5935440","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935440","url":null,"abstract":"Piezoelectric ultrasonic horn actuators are used in high power medical/surgical, automotive, food preparation, textile cutting, and material joining applications. Typically, these horn actuators are assembled by pre-stressing piezoelectric rings between the horn and backing layer using a pre-stress bolt. In the ultrasonic horn actuators presented in this paper the bolt was removed and the number of overall parts was reduced significantly allowing for easy fabrication and integration of the actuators into other structures. The elimination of the need for the conventional stress bolt internal to the piezoelectric stack and the reduction of the related complexity were achieved by using external flexures. The actuator structure was produced by an electron beam melting rapid prototype manufacturing process. This manufacturing process allows for horn structures with internal cavities if required. This design allows for using solid piezoelectric stacks (with no central hole) to produce a highly effective actuator. This paper presents the results of a novel design of a monolithic ultrasonic horn.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72790526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In-line rheometry for highly filled suspensions through Doppler ultrasound","authors":"S. Ricci, B. Birkhofer, D. Lootens, P. Tortoli","doi":"10.1109/ULTSYM.2010.5935438","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935438","url":null,"abstract":"For chemical, cosmetic, pharmaceutical, and food industries the rheological properties of a product represent an important quality factor. Unfortunately such features are often difficult to estimate, in particular in a continuous production process. In this work, we present an ultrasound (US) Doppler method suitable for in-line rheological assessment of highly filled opaque suspensions. The velocity profile developed by highly filled and opaque polyurethane based adhesives and sealants flowing in a pipe was measured through a proprietary US board. The high resolution profile was then fitted to the power law model and the wall shear rate (WSR), a reliable rheological indicator in high shear-thinning suspensions, was obtained. The accuracy of the method was evaluated comparing the measured WSR to reference values obtained from off-line laboratory rheometry. The error from 78 measurements at flow rates between 1 and 35 ml/s featured a mean +3.6% bias and a standard deviation below 12%. Moreover, measurements are only minimally affected by the variation of several US parameters over a wide range of values demonstrating the robusness of the technique.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74605320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}