2010 IEEE International Ultrasonics Symposium最新文献

Modeling nonlinear acoustic wave fields in media with inhomogeneity in the attenuation and in the nonlinearity 衰减和非线性不均匀介质中非线性声波场的模拟

2010 IEEE International Ultrasonics Symposium Pub Date : 2010-12-01 DOI: 10.1109/ULTSYM.2010.5935492

L. Demi, M. Verweij, N. D. Jong, K. V. Dongen

{"title":"Modeling nonlinear acoustic wave fields in media with inhomogeneity in the attenuation and in the nonlinearity","authors":"L. Demi, M. Verweij, N. D. Jong, K. V. Dongen","doi":"10.1109/ULTSYM.2010.5935492","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935492","url":null,"abstract":"Biomedical tissues usually show inhomogeneity in their acoustic medium parameters. These inhomogeneities cause refraction and scattering of diagnostic and therapeutic ultrasound waves. A method that is able to model the effects of inhomogeneity in the attenuation and in the nonlinearity is essential for the design of transducers for new ultrasound modalities and the development of novel ultrasound applications. The Iterative Nonlinear Contrast Source (INCS) method has originally been designed for the accurate modeling of nonlinear acoustic wave fields in homogeneous media. It considers the nonlinear term from the Westervelt equation as a distributed contrast source, and the corresponding integral equation is solved using an iterative Neumann scheme. This paper presents an extension of the INCS method that can handle inhomogeneity in the attenuation and in the coefficient of nonlinearity. Results are presented for the one-dimensional case. These show that in this case the presented method correctly predicts the effects related to nonlinear propagation and scattering by inhomogeneities in the attenuation and the coefficient of non-linearity.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78421687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Lipid distribution and viscosity of coated microbubbles 包被微泡的脂质分布和粘度

2010 IEEE International Ultrasonics Symposium Pub Date : 2010-12-01 DOI: 10.1109/ULTSYM.2010.5935903

K. Kooiman, M. Emmer, T. Kokhuis, J. Bosch, H. D. de Gruiter, M. V. van Royen, W. V. van Cappellen, A. Houtsmuller, A. V. D. van der Steen, N. de Jong

{"title":"Lipid distribution and viscosity of coated microbubbles","authors":"K. Kooiman, M. Emmer, T. Kokhuis, J. Bosch, H. D. de Gruiter, M. V. van Royen, W. V. van Cappellen, A. Houtsmuller, A. V. D. van der Steen, N. de Jong","doi":"10.1109/ULTSYM.2010.5935903","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935903","url":null,"abstract":"Ultrasound contrast agents consist of gas-filled coated microbubbles with diameters between 1 and 10 µm. Within an ultrasound field, high differences in responses of similar sized microbubbles have been reported. Heterogeneous coating properties have been suggested to be the underlying cause. Until now, properties of this coating, like viscosity have been studied dynamically using a set-up of vibrating microbubbles in an ultrasound field. This study focuses on determining the viscosity of the coating for lipid-coated microbubbles in a static set-up. The viscosity of the coating was determined by measuring the mobility of a fluorescent lipid using Fluorescence Recovery After Photobleaching (FRAP). We found a surface shear viscosity of 8×10−6 kg/s that was independent of the microbubble size. In addition, we found that the lipid distribution in the coating was heterogeneous and varied from microbubble to microbubble. In conclusion, this study shows that the static surface shear viscosity of the coating can be determined in an independent way which can now be used in microbubble dynamics models.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79884520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

A simple technique for obtaining (1120) or (1010) textured ZnO films by RF bias sputtering 一种通过射频偏置溅射获得(1120)或(1010)织化ZnO薄膜的简单技术

2010 IEEE International Ultrasonics Symposium Pub Date : 2010-12-01 DOI: 10.1109/ULTSYM.2010.5935655

S. Takayanagi, T. Yanagitani, M. Matsukawa, Yoshiaki Watanabe

引用次数: 5

Design of a low power time-gain-compensation amplifier for a 2D piezoelectric ultrasound transducer 二维压电超声换能器低功率时增益补偿放大器的设计

2010 IEEE International Ultrasonics Symposium Pub Date : 2010-12-01 DOI: 10.1109/ULTSYM.2010.5935775

J. Yao, Z. Yu, M. Pertijs, G. Meijer, C. Lancée, J. Bosch, N. de Jong

引用次数: 12

Efficacy of perfluorobutane as a phase-change contrast agent for low-energy ultrasonic imaging 全氟丁烷作为相变造影剂在低能超声成像中的效果

2010 IEEE International Ultrasonics Symposium Pub Date : 2010-12-01 DOI: 10.1109/ULTSYM.2010.5935592

P. Sheeran, Vincent P. Wong, R. J. McFarland, William D. Ross, S. Feingold, T. Matsunaga, P. Dayton

{"title":"Efficacy of perfluorobutane as a phase-change contrast agent for low-energy ultrasonic imaging","authors":"P. Sheeran, Vincent P. Wong, R. J. McFarland, William D. Ross, S. Feingold, T. Matsunaga, P. Dayton","doi":"10.1109/ULTSYM.2010.5935592","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935592","url":null,"abstract":"Most gas-filled ultrasound contrast agents are produced range of several microns in diameter, which limits them to flow within intravascular space. One mechanism proposed to produce extravascular imaging agents is acoustic droplet vaporization. Liquid perfluorocarbon droplets can be manufactured in the sub-micron range and can then passively diffuse through leaky tumor vasculature. It is hypothesized that once extravasated, these droplets could be converted to microbubbles in the micron range through additional energy input in the form of ultrasound, resulting in enhanced imaging contrast. Recent studies show current formulations of phase-change contrast agents in the sub-micron range may require substantial acoustic energy to vaporize, which increases the chance of bioeffects. Thus, phase-change contrast agents with reduced acoustic activation energies would have significant advantages. In this study, the generation and activation of novel phase-change contrast agents formulated with perfluorobutane is demonstrated. Perfluorobutane — normally a gas at room temperature — can be incorporated into metastable liquid sub-micron droplets with lipid encapsulation methods. The resulting droplets are shown to be acoustically vaporizable with substantially less energy than other compounds proposed for phase-change contrast agents such as perfluoropentane and perfluorohexane.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86824487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A possible mechanism causing subharmonics in ultrasonic testing of a closed crack 在封闭裂纹的超声波检测中引起次谐波的可能机制

2010 IEEE International Ultrasonics Symposium Pub Date : 2010-12-01 DOI: 10.1109/ULTSYM.2010.5935556

K. Naito, T. Sugiura

{"title":"A possible mechanism causing subharmonics in ultrasonic testing of a closed crack","authors":"K. Naito, T. Sugiura","doi":"10.1109/ULTSYM.2010.5935556","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935556","url":null,"abstract":"Nowadays nondestructive testing is noted due to the need of maintenance in structures, such as nuclear energy plants and aircrafts. However, detection and sizing of a closed crack are difficult by the conventional ultrasonic testing, because ultrasonic waves penetrate the contact area of the closed crack. Now nonlinear ultrasonic testing is attracting attention. Though there have been experimental reports on superharmonics or subharmonics and some theoretical researches accounting the superharmonics, so far there have yet been few reports that clarify the mechanism causing the subharmonics. Generation of superharmonics at a closed crack was theoretically explained by modeling the contact of the crack surfaces as a nonlinear spring. This modeling is based on the fact that, when the gap between the crack surfaces decreases, the contact pressure increases nonlinearly due to the asperity of the crack surfaces. In this study a closed crack was regarded as a nonlinear spring with up to the third order terms, and nonlinear analysis and numerical simulation were carried out. In experiment, two aluminum specimens strongly pressed were used in place of a metal block with a closed crack. Numerical simulation predicts generation of the subharmonics. They can appear if the input frequency close to twice the natural frequency. Conditions for the subharmonics can also be found analytically with respect to the input frequency and the input amplitude. Subharmonics were also confirmed by experiment. In conclusion, a possible mechanism causing the subharmonics at a closed crack was explained by regarding a closed crack as a nonlinear spring with up to the third order terms.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83923857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Photoacoustic imaging with biodegradable plasmonic nanoclusters 生物可降解等离子体纳米团簇的光声成像

2010 IEEE International Ultrasonics Symposium Pub Date : 2010-12-01 DOI: 10.1109/ULTSYM.2010.5935805

S. Yoon, S. Mallidi, J. Tam, Justina Tam, Avinash K. Murthy, K. Johnston, K. Sokolov, S. Emelianov

引用次数: 0

Subharmonic spectroscopy of ultrasound contrast agents 超声造影剂的次谐波光谱

2010 IEEE International Ultrasonics Symposium Pub Date : 2010-12-01 DOI: 10.1109/ULTSYM.2010.5935706

T. Faez, M. Emmer, M. Docter, M. Versluis, N. de Jong

引用次数: 3

The Luxembourg-Gorky effect for in vitro characterization of lipid-coated microbubbles 脂包微泡体外表征的卢森堡-高尔基效应

2010 IEEE International Ultrasonics Symposium Pub Date : 2010-12-01 DOI: 10.1109/ULTSYM.2010.5935699

G. Renaud, J. Bosch, A. V. D. van der Steen, N. de Jong

{"title":"The Luxembourg-Gorky effect for in vitro characterization of lipid-coated microbubbles","authors":"G. Renaud, J. Bosch, A. V. D. van der Steen, N. de Jong","doi":"10.1109/ULTSYM.2010.5935699","DOIUrl":"https://doi.org/10.1109/ULTSYM.2010.5935699","url":null,"abstract":"The Luxembourg-Gorky effect, defined as a transfer of amplitude-modulation from one wave to a second wave, is applied to lipid-coated microbubbles tailored for nonlinear contrast ultrasound imaging. This nonlinear effect is non-classical because not created in micro-homogeneous media. A simple experimental set-up allowing the dual-frequency dual-beam insonification of single bubbles was developed to study the interaction between a high-frequency probing ultrasonic wave and an amplitude-modulated low-frequency wave. Low-amplitude acoustic pressures are employed for both waves to reduce acoustically induced non-reversible processes. The frequency of the probing wave lies above the resonance frequency of microbubbles such that the pressure amplitude scattered by a single bubble is proportional to its diameter. As a result the bubble radial oscillation induced by the low-frequency wave produces an amplitude modulation and a phase modulation in the high-frequency signal scattered by single bubbles. The analysis of the latter signal provides direct access to the LF radial motion of bubbles. Using the high-frequency signal recorded before and after the LF manipulation as a reference, we show how the Luxembourg-Gorky effect can be used to quantify the asymmetry in acoustical induced vibrations of lipid-coated microbubbles. Among 220 investigated single bubbles, 49% exhibited full compression-only behavior. This low-amplitude highly nonlinear behavior is of great interest for medical contrast ultrasound imaging. Further work will aim at developing an ”single-bubble acoustical camera” able to derive the absolute value of the radial oscillation.","PeriodicalId":6437,"journal":{"name":"2010 IEEE International Ultrasonics Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76048128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Combined use of iteration, quadratic interpolation and an extra kernel for high-resolution 2D particle tracking: A first evaluation 结合使用迭代，二次插值和一个额外的核高分辨率二维粒子跟踪:第一次评估

2010 IEEE International Ultrasonics Symposium Pub Date : 2010-12-01 DOI: 10.1109/ULTSYM.2010.5935430

J. Albinsson, S. Brorsson, F. Lindgren, Å. R. Ahlgren, M. Cinthio

引用次数: 2