{"title":"Antitumor Activity of Escin in Mice Cervical Carcinoma U_(14) In Vivo and Human Cervical Carcinoma Hela Cell Line In Vitro","authors":"Xueying Zhou, Changhai Wang, F. Fu","doi":"10.1109/ICBBE.2009.5162378","DOIUrl":"https://doi.org/10.1109/ICBBE.2009.5162378","url":null,"abstract":"Pollution made cancer a major disease threatening people's health. In the search for new cancer drug treatments, natural products perform an essential role. Escin, a mixture of triterpene saponins extracted from Aesculus Wilsonii Rehd., was used to analyze the cell growth inhibitory effects and the induction of apoptosis in human cervical carcinoma Hela cancer cell line in vitro. The results of MTT cell viability assay showed that escin could induce significant concentration-dependent and time-dependent inhibition of cell growth, and the cell cycle was arrested at G 1 /S phase in the escin-treated cells. Apoptosis were detected and assessed by Acridine Orange/Ethidium Bromide Staining and Flow Cytometry. The antitumor efficacy of escin on mice cervical carcinoma U_(14) in vivo was investigated, at dose of 2.8 mg/kg escin had rather high inhibition ratio(43.5%) on U_(14) tumor growth.","PeriodicalId":6430,"journal":{"name":"2009 3rd International Conference on Bioinformatics and Biomedical Engineering","volume":"11 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2009-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78378064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Urban Water Sustainable Utilization","authors":"H. Cui, Jun Liu, C. Gao, Fangqing Yu","doi":"10.1109/ICBBE.2009.5163732","DOIUrl":"https://doi.org/10.1109/ICBBE.2009.5163732","url":null,"abstract":"The prevalent water problems like quantity shortage, environment pollution and ecological damage restrict urban sustainable development. Unreasonable water utilizing causes conflicts between artificial water cycling system and natural cycling water system, which turns out to be the source of urban water problems. To find ultimate solutions to the water problems and the way of sustainable water utilization, artificial water cycling system with the whole urban water ecosystem is analyzed. After a comparative analysis of urban water ecosystem and steady natural ecosystem, unsmooth flowing and unbalanced in-out of matter is put forward as the inducement of water problems. It is quite necessary to strengthen wastewater-disposal making it accord with exploitation and using, and to strengthen water renewal forming efficient circulation. In all, water utilizing model should be completed. Reduce, reuse, recycle principle can be applied to promote water cycling efficiency. For further study wastewater can be utilized as resources with technical innovation.","PeriodicalId":6430,"journal":{"name":"2009 3rd International Conference on Bioinformatics and Biomedical Engineering","volume":"30 17 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2009-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78410472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dan Zhang, A. Ding, Wenjie Tan, Cheng Chen, Lirong Cheng, Yujiao Sun, Xue-yu Lin
{"title":"Microcosm Study on Response of Soil Microorganisms to Polycyclic Aromatic Hydrocarbons Contamination","authors":"Dan Zhang, A. Ding, Wenjie Tan, Cheng Chen, Lirong Cheng, Yujiao Sun, Xue-yu Lin","doi":"10.1109/ICBBE.2009.5163052","DOIUrl":"https://doi.org/10.1109/ICBBE.2009.5163052","url":null,"abstract":"Soil and groundwater contamination by petroleum and coal tar becomes one of the urgent environmental issues concerned by more and more scientists with regards to the public health. With the induction of organic contaminants to soil and groundwater it will change the environmental conditions within the plume and hence lead to the variation of indigenous microorganisms. The article aims to investigate the response of indigenous microorganisms to the petroleum contamination. Three polycyclic aromatic hydrocarbons (PAHs) phenanthrene, anthracene and pyrene were selected as the contaminants and tested using laboratory microcosm. The response of indigenous microorganisms to the PAHs induction was analyzed by measuring the change of soil microbial activity, soil catalase activity, contaminants concentration and geochemical parameters. The experimental results showed that: (1) the major parts of the PAHs were absorbed by the soil, its transport was retarded, (2) the soil microbial activity was inhibited at the initial stage of PAHs induction and then slowly increased, (3) the soil catalase activity was stimulated at first with PAHs induction and then inhibited within the range -0.05 mL (0.1 M KMnO 4 )/g (soil).","PeriodicalId":6430,"journal":{"name":"2009 3rd International Conference on Bioinformatics and Biomedical Engineering","volume":"1 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2009-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76148853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. M. Chen, G. X. Zhao, L. S. Zhang, J. Y. Guo, H. X. Yang, Z. M. Li
{"title":"Investigation of Resistivity's Abnormity and Moduli of Elasticity Softening in NiTi Shape Memory Alloy","authors":"F. M. Chen, G. X. Zhao, L. S. Zhang, J. Y. Guo, H. X. Yang, Z. M. Li","doi":"10.1109/ICBBE.2009.5162982","DOIUrl":"https://doi.org/10.1109/ICBBE.2009.5162982","url":null,"abstract":"Spreading the landau phase change theory, by using two order parameters, that is martensite transition percentange Φ and mean shearing strain ε, and supposing friction function is the first-order linear coupling of them. Explaining the experimental facts of resistivity’s abnormal raising and moduli of elasticity’s softening on the Thermoelastic Martensitic Tansformation. Keywords-phase transformations; stress; thermoelastic martensite; phenomenological theory ; Shape memory effect","PeriodicalId":6430,"journal":{"name":"2009 3rd International Conference on Bioinformatics and Biomedical Engineering","volume":"21 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2009-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75027859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Contralateral Stimulation on Auditory Filter Bandwidth: A Preliminary Study","authors":"Chang Liu","doi":"10.1109/ICBBE.2009.5162691","DOIUrl":"https://doi.org/10.1109/ICBBE.2009.5162691","url":null,"abstract":"The main goal of this study was to examine the effect of contralateral stimulation on auditory filter shape. Auditory filter was measured at 1 and 2 kHz for normal-hearing listeners using notched-noise method with and without contralateral stimulation presented. A broadband noise was presented as contralateral stimulation at three levels: 50, 60, and 70 dB SPL. Results indicated that contralateral stimulation at 50 dB SPL slightly increased frequency selectivity (i.e. reduced auditory filter bandwidth) for 2 kHz, suggesting that auditory efferent fibers such as medial olivocochlear bundles may function to improve frequency selectivity of the cochlear. Such improvement in the cochlear frequency selectivity appeared to be dependent on signal frequency and intensity of contralateral stimulation.","PeriodicalId":6430,"journal":{"name":"2009 3rd International Conference on Bioinformatics and Biomedical Engineering","volume":"26 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2009-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74987843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development and Validity of Tissue Biomechanics Modeling for Virtual Robot Assisted Orthopedic Surgery System","authors":"Monan Wang","doi":"10.1109/ICBBE.2009.5162638","DOIUrl":"https://doi.org/10.1109/ICBBE.2009.5162638","url":null,"abstract":"Information with respect to the internal stresses/strains in the human leg during bone-setting is helpful to control the medical robots in HIT-robot assisted orthopedic surgery system (HIT-RAOS). While techniques to measure external pressure are well established, direct measurement of the internal stresses/strains is difficult. A three-dimensional (3D) finite element model of the human leg is developed using the actual geometry of the leg skeleton and soft tissues, which were obtained from 3D reconstruction of CT images. The major tendons are simulated using tension-only truss elements by connecting the corresponding attachment points on the bone surfaces. The bony structures are defined as linearly elastic, while the soft tissue and muscles are assumed to be hyper elastic. The bony and tendons structures are embedded in a volume of soft tissues. To validate this model, the same cadaver is utilized in experiment, during reposition procedure, the force needed to separate the two broken bones and corresponding the distance are recorded. Then, another set of data is acquired from the finite element analysis. After comparison, the finite element model is proved to be acceptable. This simulation model is used in virtual HIT-robot assisted orthopedic surgery system.","PeriodicalId":6430,"journal":{"name":"2009 3rd International Conference on Bioinformatics and Biomedical Engineering","volume":"40 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2009-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77713390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Su-yun Chang, Jingmei Sun, Jianjun Huang, Baosheng Sun, P. Sun
{"title":"Cultivation of High Cell Density to Improve Degradation Efficiency of River-Water","authors":"Su-yun Chang, Jingmei Sun, Jianjun Huang, Baosheng Sun, P. Sun","doi":"10.1109/ICBBE.2009.5162566","DOIUrl":"https://doi.org/10.1109/ICBBE.2009.5162566","url":null,"abstract":"Technology of bioaugmentation was used to degrade contaminants of river water. It was realized that degradation effectives was affected by the density of added microbes. Improving the density of microbes was necessary to reach satisfactory degradation effects on the contaminated river. Therefore a practical recycle cultivation method was studied. It was proved to be practical and effective, for easy to combine with air-lift bioreactor, and the process was easy to implement and take low cost. To achieve high cell density and keep them with high activity, three times cycle was the optimum. It was noticed that recycle cultivation was affected by centrifuge temperature and carbon concentration. More carbon source and higher centrifugal temperature were required to harvest high cell density. But for degradation ability of individual microbe, more carbon was not effective. Finally recycle culture was ended at low centrifugal temperature or higher, because a lot of gels were produced. The gels wrap to the cells so firmly that the cells can't uptake the nutrient and their activities were limited.","PeriodicalId":6430,"journal":{"name":"2009 3rd International Conference on Bioinformatics and Biomedical Engineering","volume":"12 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2009-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78035315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yanguo Teng, J.Y. Xiao, Q. Zhang, R. Zuo, Jinsheng Wang, Jie Yang
{"title":"Bioavailable Vanadium Extracting with EDTA in Panzhihua Urban Park Topsoil","authors":"Yanguo Teng, J.Y. Xiao, Q. Zhang, R. Zuo, Jinsheng Wang, Jie Yang","doi":"10.1109/ICBBE.2009.5162440","DOIUrl":"https://doi.org/10.1109/ICBBE.2009.5162440","url":null,"abstract":"Vanadium was a trace element, which may be biologically beneficial and possibly essential but certainly harmful to human beings and some living organisms if excessive. In order to investigate potentially environmental risk of vanadium, a total of 46 topsoil samples were collected in dry and wet season in Panzhihua urban park. The concentration of bioavailable vanadium in wet season was higher than that in the dry season. The higher concentration of bioavailable vanadium was distributed in the gateway, the children's pleasure ground and the resting place. In contrast to the toxicity reference values (TRV) in Eco-SSLs for vanadium in the soil and bioavailable vanadium, there was a slight health risk. So some countermeasures of reducing pollution of vanadium in urban park soil should be put forward.","PeriodicalId":6430,"journal":{"name":"2009 3rd International Conference on Bioinformatics and Biomedical Engineering","volume":"193 1 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2009-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79784922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of Sewage Sludge Application on Growth of Maize Grown in Aluminum-Toxic Soils","authors":"Qiang Liu, X. Zou, C. Xiao, L. Luo","doi":"10.1109/ICBBE.2009.5162753","DOIUrl":"https://doi.org/10.1109/ICBBE.2009.5162753","url":null,"abstract":"In the present study, a pot experiment was conducted to investigate the ameliorative effects of sewage sludge on maize grown in acid soils by measuring plant growth and physiological responses. The sewage sludge had higher pH and organic matter than red soil, thus the application of sewage sludge significantly increased soil pH and decreased monomeric aluminum (Al) concentration in soil solution. In general, there was a trend of increasing plant height, fresh weight, chlorophyll (Chi) content and activities of peroxides (POD) and catalase (CAT), or decreasing contents of malondialdehyde (MDA) and membrane permeability (MP), with sewage sludge ratio increased from 0% to 10%. However, those index mentioned above were opposite at a higher sewage sludge application ratio, ie. 30%, partly due to the high contents of soluble salts and NH 4 -N in sewage sludge. The physiological amelioration (such as keeping higher activities of POD and CAT, more chlorophyll content and lower contents of MDA and MP) for maize grown in Al-toxic soils at 10% sewage sludge ratio provides foundations for the tolerance to Al, thus resulting in highest plant growth.","PeriodicalId":6430,"journal":{"name":"2009 3rd International Conference on Bioinformatics and Biomedical Engineering","volume":"89 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2009-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80305247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pinaki S. Mitra, Vanathi Gopalakrishnan, R. McNamee
{"title":"Utilization of Spatial Coherence in Functional Neuroimage-Based Classification","authors":"Pinaki S. Mitra, Vanathi Gopalakrishnan, R. McNamee","doi":"10.1109/ICBBE.2009.5163742","DOIUrl":"https://doi.org/10.1109/ICBBE.2009.5163742","url":null,"abstract":"Functional magnetic resonance imaging provides a non-invasive mechanism for monitoring brain activity of subjects during performance of a task. While this approach has been used extensively for human brain mapping activities, automated classification of subjects based on neural activation patterns is also of interest. However, due to the high dimensionality of the image data, classification accuracy is highly dependent upon the adequacy of the features used in the models. In this work 1 , we present a new feature refinement strategy that uses spatial coherence information to eliminate irrelevant features from consideration. For a neurobehavioral disinhibition dataset, we show that this new approach for feature selection using spatially coherent voxels (SCV) outperforms conventional methods.","PeriodicalId":6430,"journal":{"name":"2009 3rd International Conference on Bioinformatics and Biomedical Engineering","volume":"165 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2009-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80416590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}