生物医学工程(英文)最新文献_第8页

EEG Analysis of the Contribution of Music Therapy and Virtual Reality to the Improvement of Cognition in Alzheimer’s Disease 音乐治疗和虚拟现实对阿尔茨海默病认知改善作用的脑电图分析

生物医学工程(英文) Pub Date : 2020-08-13 DOI: 10.4236/jbise.2020.138018

A. Byrns, H. Abdessalem, M. Cuesta, M. Bruneau, S. Belleville, C. Frasson

{"title":"EEG Analysis of the Contribution of Music Therapy and Virtual Reality to the Improvement of Cognition in Alzheimer’s Disease","authors":"A. Byrns, H. Abdessalem, M. Cuesta, M. Bruneau, S. Belleville, C. Frasson","doi":"10.4236/jbise.2020.138018","DOIUrl":"https://doi.org/10.4236/jbise.2020.138018","url":null,"abstract":"Alzheimer’s disease is the most common form of dementia, affecting nearly 9.9 million new people every year. The disease provokes important memory and cognitive impairment, eventually causing individuals to forget their loved ones and rendering them completely dependent on their caretakers. Alzheimer’s patients typically experience more negative emotions, such as frustration and apathy, than healthy older adults. There is currently no cure for the disease. Our research group explores how the integration of virtual reality (VR) and an EEG-based intelligent agent in music therapy can alleviate psychological and cognitive symptoms of the disease. We propose a theory explaining how, through activation of the brain reward system, music can reduce negative emotions, increase positive emotions and as a result increase performance on cognitive tasks. The results of our experimental study concord with our theory: emotional states of participants are improved, as per recorded through EEG, and performances on memory tasks show improvement following the intervention. We believe that the combination of EEG brain assessment, VR and music therapy is a promising method for emotional states and cognitive symptoms of Alzheimer’s disease.","PeriodicalId":64231,"journal":{"name":"生物医学工程(英文)","volume":"13 1","pages":"187-201"},"PeriodicalIF":0.0,"publicationDate":"2020-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44606355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Brain Tumor Classification in Magnetic Resonance Images Using Deep Learning and Wavelet Transform 基于深度学习和小波变换的磁共振图像脑肿瘤分类

生物医学工程(英文) Pub Date : 2020-06-11 DOI: 10.4236/jbise.2020.136010

A. Sarhan

引用次数: 47

Prediction of Intraoperative Fracture by Hammering Sound Frequency Analysis and Stress Estimation during Total Hip Arthroplasty 全髋关节置换术中锤击声频率分析及应力估计预测术中骨折

生物医学工程(英文) Pub Date : 2020-06-11 DOI: 10.4236/jbise.2020.136011

R. Sakai, Takeaki Yamamoto, K. Uchiyama, Kensuke Fukushima, N. Takahira, Kazuhiro Yoshida, M. Ujihira

{"title":"Prediction of Intraoperative Fracture by Hammering Sound Frequency Analysis and Stress Estimation during Total Hip Arthroplasty","authors":"R. Sakai, Takeaki Yamamoto, K. Uchiyama, Kensuke Fukushima, N. Takahira, Kazuhiro Yoshida, M. Ujihira","doi":"10.4236/jbise.2020.136011","DOIUrl":"https://doi.org/10.4236/jbise.2020.136011","url":null,"abstract":"When a stem is inserted into the femur during total hip arthroplasty, sufficient fixation depends on the surgeon’s experience. An objective method of evaluating whether the stem has been correctly fixed may aid clinicians in their decision. We examined the relationship between the sound frequency caused by hammering the stem and the internal stress in artificial femurs, and evaluated the utility of sound frequency analysis to prevent intraoperative fracture. Surgeons inserted one of two types of cementless stems (SL-PLUS and modified CLS) using routine operational procedures into 13 artificial femurs. These are the standard Zweymullers used in Europe. The difference is the lateral shape; SL-PLUS has holes for removal and the modified CLS has fins to prevent rotation. We estimated stress in the femur via finite element analysis, measured the hammering force, and recorded the sound of hammering for frequency analysis. Finite element analysis revealed that the hammering sound frequency decreased as the maximum stress increased. A decrease in frequency suggested that fixation was sufficient and that continued hammering would increase the risk of fracture. Thus, evaluation of the change in sound frequency during stem insertion may indicate when the hammering force should be reduced, thereby preventing intraoperative periprosthetic fractures. Further frequency change may also predict fractures prior to visual confirmation. We concluded that sound frequency analysis has potential as an objective evaluation method to help prevent intraoperative periprosthetic fractures during stem insertion.","PeriodicalId":64231,"journal":{"name":"生物医学工程(英文)","volume":"13 1","pages":"113-119"},"PeriodicalIF":0.0,"publicationDate":"2020-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41344083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Comparison of Plasma Levels of Tryptophan Metabolites between Healthy People and Patients of Bipolar Depression at Various Age and Gender 不同年龄和性别健康人与双相抑郁症患者血浆色氨酸代谢产物水平的比较

生物医学工程(英文) Pub Date : 2020-06-11 DOI: 10.4236/jbise.2020.136012

H. Tomioka, J. Masuda, A. Takada, A. Iwanami

引用次数: 2

Numerical Investigation of Flexural Bending in Biaxial Braided Structures for Flexor Tendon Repair 屈肌腱修复中双轴编织结构弯曲弯曲的数值研究

生物医学工程(英文) Pub Date : 2020-06-11 DOI: 10.4236/jbise.2020.136009

J. Ochola, B. Malengier, L. Langenhove

{"title":"Numerical Investigation of Flexural Bending in Biaxial Braided Structures for Flexor Tendon Repair","authors":"J. Ochola, B. Malengier, L. Langenhove","doi":"10.4236/jbise.2020.136009","DOIUrl":"https://doi.org/10.4236/jbise.2020.136009","url":null,"abstract":"Flexor tendon repair has conventionally been done by suturing techniques. However, in recent times, there have been attempts of using fibrous braided structures for the repair of ruptured tendons. In this regard, the numerical analysis of the flexural stiffness of a braided structure under bending moments is vital for understanding its capabilities in the repair of flexor tendons. In this paper, the bending deflection, curvature, contact stresses and flexural bending stiffness in the braided structure due to bending moments are simulated using Finite Element (FE) techniques. Three dimensional geometry and FE models of five sets of biaxial braided structures were developed using a python programming script. The FE models of the hybrid biaxial braids were imported into ABAQUS (v17) for post-processing and analysis. It was established that the braided fabric with largest braid angle, θ = 52.5˚ had the highest flexural deflection while the lowest deflection was seen in the results of the braided structure with the least braid angle, θ = 38.5˚. The results in this study also portrayed that the curvature in biaxial braids will increase with a decrease in the angle between the braided yarns. This was also consistent with the change of bending angle of the biaxial structures under a bending moment. The deformation of the structures increased with increase in the braid angles. This implies that the flexural bending stiffness decreased with increase in braid angle. The stress limits during bending of the braided structures were established to be within the range that could be handled by flexor tendons during finger bending.","PeriodicalId":64231,"journal":{"name":"生物医学工程(英文)","volume":"13 1","pages":"93-101"},"PeriodicalIF":0.0,"publicationDate":"2020-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46845913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Application of the Somatosensory Interaction Technology Combined with Virtual Reality Technology on Upper Limbs Function in Cerebrovascular Disease Patients 体感交互技术结合虚拟现实技术在脑血管病患者上肢功能研究中的应用

生物医学工程(英文) Pub Date : 2020-05-20 DOI: 10.4236/jbise.2020.135006

Wangxiang Mai, Liang Fang, Zhuoming Chen, Xiuping Wang, Wanting Li, Weiyi He

{"title":"Application of the Somatosensory Interaction Technology Combined with Virtual Reality Technology on Upper Limbs Function in Cerebrovascular Disease Patients","authors":"Wangxiang Mai, Liang Fang, Zhuoming Chen, Xiuping Wang, Wanting Li, Weiyi He","doi":"10.4236/jbise.2020.135006","DOIUrl":"https://doi.org/10.4236/jbise.2020.135006","url":null,"abstract":"Objective: To explore the effects of the somatosensory interaction technology combined with virtual reality technology on upper limbs function and activities of daily living (ADL) in cerebrovascular disease patients. Methods: Form January, 2019 to December, 2019, 80 cerebrovascular disease patients were recruited, and had been divided into control group (n = 40) and observation group (n = 40), randomly. The control groups received conventional rehabilitation treatment, for 40 minutes per day, while observation group received conventional rehabilitation treatment, for 20 minutes per day, and virtual reality technology treatment, 20 minutes per day, 5 days a week for 4 weeks. Wolf Motor Function Test (WMFT), Fugl-Meyer Assessment-Upper Extremities (FMA-UE) and modified Barthel index (MBI) were used to assess the motor function of the upper limbs and ADL before and after treatment. Results: Before treatment, the scores of WMFT, FMA-UE and MBI were no significant difference between two groups (P > 0.05). The scores improved in both groups after treatment (P < 0.01), and were higher in the observation group than in the control group (P < 0.05). Conclusion: The somatosensory interaction technology combined with virtual reality technology could facilitate to improve the upper limbs function and ADL in cerebrovascular disease patients.","PeriodicalId":64231,"journal":{"name":"生物医学工程(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46874072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

pLoc_Deep-mGpos: Predict Subcellular Localization of Gram Positive Bacteria Proteins by Deep Learning pLoc_Dep-mGpos：通过深度学习预测革兰氏阳性菌蛋白质的亚细胞定位

生物医学工程(英文) Pub Date : 2020-05-11 DOI: 10.4236/jbise.2020.135005

Zhe Lu, K. Chou

{"title":"pLoc_Deep-mGpos: Predict Subcellular Localization of Gram Positive Bacteria Proteins by Deep Learning","authors":"Zhe Lu, K. Chou","doi":"10.4236/jbise.2020.135005","DOIUrl":"https://doi.org/10.4236/jbise.2020.135005","url":null,"abstract":"The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological process within a cell level and provide useful clues to develop antiviral drugs, information of Gram positive bacteria protein subcellular localization is vitally important. In view of this, a CNN based protein subcellular localization predictor called “pLoc_Deep-mGpos” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 99% and its local accuracy is around 92% - 99%. Both are transcending other existing state-of-the-art predictors significantly. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at http://www.jci-bioinfo.cn/pLoc_Deep-mGpos/, which will become a very powerful tool for developing effective drugs to fight pandemic coronavirus and save the mankind of this planet.","PeriodicalId":64231,"journal":{"name":"生物医学工程(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48567167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A Novel Lung Cancer Detection Method Using Wavelet Decomposition and Convolutional Neural Network 基于小波分解和卷积神经网络的肺癌检测新方法

生物医学工程(英文) Pub Date : 2020-05-11 DOI: 10.4236/jbise.2020.135008

A. Sarhan

引用次数: 4

Usefulness of Hammering Sound Frequency Analysis as an Evaluation Method for the Prevention of Trouble during Hip Replacement 锤击声频率分析作为髋关节置换术中预防问题的评估方法的有用性

生物医学工程(英文) Pub Date : 2020-05-11 DOI: 10.4236/jbise.2020.135007

R. Sakai, K. Uchiyama, N. Takahira, M. Kakeshita, Y. Otsu, Kazuhiro Yoshida, M. Ujihira

引用次数: 4

Detection and Classification of Brain Tumor Based on Multilevel Segmentation with Convolutional Neural Network 基于卷积神经网络多层次分割的脑肿瘤检测与分类

生物医学工程(英文) Pub Date : 2020-04-30 DOI: 10.4236/jbise.2020.134004

Rafiqul Islam, S. Imran, M. Ashikuzzaman, Md. Munim Ali Khan

引用次数: 27