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航天医学与医学工程最新文献

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[Development of a portable ambulatory ECG monitor based on embedded microprocessor unit]. 基于嵌入式微处理器的便携式动态心电监护仪的研制
航天医学与医学工程 Pub Date : 2005-06-01
Da-xiong Wang, Guo-jun Wang
{"title":"[Development of a portable ambulatory ECG monitor based on embedded microprocessor unit].","authors":"Da-xiong Wang,&nbsp;Guo-jun Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To develop a new kind of portable ambulatory ECG monitor.</p><p><strong>Method: </strong>The hardware and software were designed based on RCA-CDP1802. New methods of ECG data compression and feature extraction of QRS complexes were applied to software design. A model for automatic arrhythmia analysis was established for real-time ambulatory ECG Data analysis. Compact, low power consumption and low cost were emphasized in the hardware design.</p><p><strong>Result: </strong>This compact and light-weight monitor with low power consumption and high intelligence was capable of real-time monitoring arrhythmia for more than 48 h. More than ten types of arrhythmia could be detected, only the compressed abnormal ECG data was recorded and could be transmitted to the host if required.</p><p><strong>Conclusion: </strong>The monitor meets the design requirements and can be used for ambulatory ECG monitoring.</p>","PeriodicalId":63677,"journal":{"name":"航天医学与医学工程","volume":"18 3","pages":"196-200"},"PeriodicalIF":0.0,"publicationDate":"2005-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25298822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The influence of circadian gene mPeriod2 on Lewis cancer cell]. [节律基因mPeriod2对Lewis癌细胞的影响]。
航天医学与医学工程 Pub Date : 2005-06-01
Yue-qi Wang, Hui Hua, Bin Zhu, Hua-hu Yin, Yan-you Liu, Chun-lei Yang, Zheng-rong Wang
{"title":"[The influence of circadian gene mPeriod2 on Lewis cancer cell].","authors":"Yue-qi Wang,&nbsp;Hui Hua,&nbsp;Bin Zhu,&nbsp;Hua-hu Yin,&nbsp;Yan-you Liu,&nbsp;Chun-lei Yang,&nbsp;Zheng-rong Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the role of circadian gene mPeriod2 (mPer2) on tumor proliferation and apoptosis.</p><p><strong>Method: </strong>The eukaryotic mPer2 expression vector (pcDNA 3.1-mPer2) based on pcDNA 3.1 was transfected into the cultured Lewis tumor cell by liposome method in vivo. The expression of mPer2 in transfected Lewis tumor cell was detected by immunohistochemistry and flowcytometry. The stable transfected cell line was screened by G418 and its proliferation and apoptosis was examined by flowcytometry.</p><p><strong>Result: </strong>Expression of PERIOD2 protein in pcDNA 3.1-mPer2 transfected Lewis tumor cell was proved by immunohistochemistry and flowcytometry. Flowcytometry result of mPer2 expression Lewis tumor cell showed less proliferation and high rate of apoptosis.</p><p><strong>Conclusion: </strong>mPer2 expression can suppress the proliferation of tumor cell and increase the apoptosis of it.</p>","PeriodicalId":63677,"journal":{"name":"航天医学与医学工程","volume":"18 3","pages":"222-3"},"PeriodicalIF":0.0,"publicationDate":"2005-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25300585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cleavage of the deoxyribozyme targeting Period1 mRNA in vitro and its effects on morphine-induced reward in mice]. [体外靶向Period1 mRNA的脱氧核酶裂解及其对吗啡诱导小鼠奖赏的影响]。
航天医学与医学工程 Pub Date : 2005-06-01
Wei Zhou, Yan-you Liu, Yue-qi Wang, Ying-hui Liu, Yu-hui Wang, Zheng-rong Wang
{"title":"[Cleavage of the deoxyribozyme targeting Period1 mRNA in vitro and its effects on morphine-induced reward in mice].","authors":"Wei Zhou,&nbsp;Yan-you Liu,&nbsp;Yue-qi Wang,&nbsp;Ying-hui Liu,&nbsp;Yu-hui Wang,&nbsp;Zheng-rong Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To study the cleavage of the deoxyribozyme targeting Period1 (Per1) mRNA in vitro and its effect on the opiate-induced reward in mice.</p><p><strong>Method: </strong>The specific deoxyribozyme (DRz164) targeting Per1 mRNA was designed after MFold analysis and being synthesized chemically. The cleavage reactions containing DRz164 and Per1 RNA fragments transcripted in vitro were performed under certain conditions. DIG Nucleic Acid Detection Kit was used to detect the cleavage activity of DRz164. The morphine-induced reward in mice was observed in a conditioned place preference test after pretreatment with DRz164.</p><p><strong>Result: </strong>When DRz164 and Per1 RNA transcripts were incubated under certain conditions with 37 degrees C for 30, 60, 90, and 120 min, about 36.4%, 40.5%, 47.8%, 63% of Per1 RNA transcripts were cleaved by DRz164 respectively. After pretreated with the deoxyribozyme, mice didn't show a morphine-induced place preference.</p><p><strong>Conclusion: </strong>DRz164 targeting per1 mRNA has the specific cleavage activity which increases with the time in vitro. Suppression of morphine-induced place preference occurs by pretreatment with the deoxyribozyme. Mice show a lack of morphine-induced reward, which alleviates the psychic dependence on the morphine.</p>","PeriodicalId":63677,"journal":{"name":"航天医学与医学工程","volume":"18 3","pages":"224-6"},"PeriodicalIF":0.0,"publicationDate":"2005-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25300586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[An automatic color correction algorithm for digital human body sections]. 一种数字人体切片的自动色彩校正算法。
航天医学与医学工程 Pub Date : 2005-06-01
Bin Zhuge, He-qin Zhou, Lei Tang, Wen-hui Lang, Huan-qing Feng
{"title":"[An automatic color correction algorithm for digital human body sections].","authors":"Bin Zhuge,&nbsp;He-qin Zhou,&nbsp;Lei Tang,&nbsp;Wen-hui Lang,&nbsp;Huan-qing Feng","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To find a new approach to improve the uniformity of color parameters for images data of the serial sections of the human body.</p><p><strong>Method: </strong>An auto-color correction algorithm in the RGB color space based on a standard CMYK color chart was proposed. The gray part of the color chart was auto-segmented from every original image, and fifteen gray values were attained. The transformation function between the measured gray value and the standard gray value of the color chart and the lookup table were obtained. In RGB color space, the colors of images were corrected according to the lookup table.</p><p><strong>Result: </strong>The color of original Chinese Digital Human Girl No. 1 (CDH-G1) database was corrected by using the algorithm with Matlab 6.5, and it took 13.475 s to deal with one picture on a personal computer.</p><p><strong>Conclusion: </strong>Using the algorithm, the color of the original database is corrected automatically and quickly. The uniformity of color parameters for corrected dataset is improved.</p>","PeriodicalId":63677,"journal":{"name":"航天医学与医学工程","volume":"18 3","pages":"211-5"},"PeriodicalIF":0.0,"publicationDate":"2005-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25298824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Regulative effects of hawthorn leave flavonoids on cytotoxicity, NO and Ca2+ in hypoxia-treated human umbilical vein endothelial cells. 山楂叶总黄酮对缺氧人脐静脉内皮细胞毒性、NO和Ca2+的调节作用。
航天医学与医学工程 Pub Date : 2005-06-01
Wen-jun Lan, Ya-kun Ge, Xiao-xiang Zheng
{"title":"Regulative effects of hawthorn leave flavonoids on cytotoxicity, NO and Ca2+ in hypoxia-treated human umbilical vein endothelial cells.","authors":"Wen-jun Lan,&nbsp;Ya-kun Ge,&nbsp;Xiao-xiang Zheng","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the potential effect of HLF (Hawthorn leave flavonoids, w/w, 80% flavonoids) against thrombus formation, effect of HLF on hypoxia-treated human umbilical vein endothelial cell (HUVECs) was studied.</p><p><strong>Method: </strong>The levels of cytotoxicity and NO upon HUVECs were studied by flow cytometry. Moreover, the level of calcium ion in HUVECs was examined through laser scanning confocal microscopy.</p><p><strong>Result: </strong>Data from this study showed that HLF at concentrations of 5 micrograms/ml and 10 micrograms/ml decreased the cytotoxicity of hypoxia to HUVECs (P<0.05, P<0.01). The intracellular levels of NO and calcium ion were downregulated by HLF at concentrations of 5 micrograms/ml (P<0.01; P<0.01) and 10 micrograms/ml (vs control, P<0.01; P<0.01) too.</p><p><strong>Conclusion: </strong>Results observed suggest that HLF protect HUVECs from hypoxia partly through its regulative effect on NO and calcium ion levels.</p>","PeriodicalId":63677,"journal":{"name":"航天医学与医学工程","volume":"18 3","pages":"157-60"},"PeriodicalIF":0.0,"publicationDate":"2005-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25300068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Progress of biological air filter (BAF) development in manned spacecraft cabin]. [载人飞船舱内生物空气过滤器(BAF)的发展进展]。
航天医学与医学工程 Pub Date : 2005-06-01
Yong-kang Tang, Shuang-sheng Guo, Wei-dang Ai
{"title":"[Progress of biological air filter (BAF) development in manned spacecraft cabin].","authors":"Yong-kang Tang,&nbsp;Shuang-sheng Guo,&nbsp;Wei-dang Ai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The contaminants originating from human metabolism, material off-gassing and waste processing, may influence human health and the growth and development of higher plants when they accumulate at some degree in the spacecraft cabin. So the contaminants concentrations must be controlled below the spacecraft maximum allowable concentration (SMAC). For the long manned space missions and planetary habitation, biological technique is available for the removal of the contaminants. The biological air filter, BAF, is a system that degrades the contaminants into carbon dioxide, water and salts. It holds many advantages such as small weight and volume, low power consumption, easy maintenance and good working performance under the condition of microgravity. Its wide application will be seen in the space field in near future.</p>","PeriodicalId":63677,"journal":{"name":"航天医学与医学工程","volume":"18 3","pages":"230-4"},"PeriodicalIF":0.0,"publicationDate":"2005-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25300588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effects of simulated weightlessness on rats mandible, lumbar vertebra and femur]. [模拟失重对大鼠下颌骨、腰椎和股骨的影响]。
航天医学与医学工程 Pub Date : 2005-06-01
Rui Guo, Min Hu, Zhen-yu Sun, Jing-wei Xue
{"title":"[Effects of simulated weightlessness on rats mandible, lumbar vertebra and femur].","authors":"Rui Guo,&nbsp;Min Hu,&nbsp;Zhen-yu Sun,&nbsp;Jing-wei Xue","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To observe the effect of weightlessness simulation on rats mandible, lumbar vertebra and femur.</p><p><strong>Method: </strong>Twenty five Wistar rats were randomly arranged into control group (n=10) and tail-suspension group (n=15 rats). The experiment lasted for 28 d. Then the mandible, lumbar vertebra and femur were excised and the histological structure of condylar process of mandible, molar and premolar area of mandible body, first lumbar, head, middle segment and condyle of femur were examined.</p><p><strong>Result: </strong>After tail-suspension there was no distinct change in bone density and bone mass of condylar process. But the degree of interlacement of trabecular bone increased. The bone substance of mandible was very dense in both control and experimental groups. There was no stimulated difference of bone structure and bone mass between the two groups. There was no marked change in the thickness of periodontal membrane. The bone lamella in premolar area of experimental group arranged regularly. And its maturity was higher than that in molar area. The line of bone hyperplasia in molar area of experimental group arranged disorderly and irregularly, which means that much bone remodeling occurred. The component of trabecular bone decreased in femur and lumbar vertebra and the thickness was uneven. The interlacement and connection among trabecular bones was poor.</p><p><strong>Conclusion: </strong>Four weeks of stimulated weightlessness can lead to osteoporosis in acantha and femur [correction of feurar] but has no distinct effect on mandible.</p>","PeriodicalId":63677,"journal":{"name":"航天医学与医学工程","volume":"18 3","pages":"165-9"},"PeriodicalIF":0.0,"publicationDate":"2005-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25300070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effects of different light-dark cycles on total and differential leukocyte counts as well as spontaneous locomotor activity in mice]. [不同明暗周期对小鼠白细胞总数和差异计数以及自发运动活动的影响]。
航天医学与医学工程 Pub Date : 2005-06-01
Li Guo, Yan-you Liu, Bo Yang, Zhou Jiang, Yue-qi Wang, Zheng-rong Wang
{"title":"[Effects of different light-dark cycles on total and differential leukocyte counts as well as spontaneous locomotor activity in mice].","authors":"Li Guo,&nbsp;Yan-you Liu,&nbsp;Bo Yang,&nbsp;Zhou Jiang,&nbsp;Yue-qi Wang,&nbsp;Zheng-rong Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effect of different light-dark cycles on total and differential counts of leukocyte as well as spontaneous locomotor activity in mice.</p><p><strong>Method: </strong>144 ICR mice were raised under different light-dark cycles including LD 7 h/7 h, LD 12 h/12 h and LD 16 h/16 h for 8 weeks. Blood samples were obtained by enucleation of eye for total and differential counts of leukocyte. Another 9 mice were also divided into 3 groups and fed under same conditions as above. Their activities were recorded continuously.</p><p><strong>Result: </strong>The change of spontaneous locomotor activity and leukocyte count were synchronized with the light-dark cycle.</p><p><strong>Conclusion: </strong>Different light-dark cycles can influence not only the spontaneous locomotor activity, but also total and differential leukocyte counts in mice.</p>","PeriodicalId":63677,"journal":{"name":"航天医学与医学工程","volume":"18 3","pages":"219-21"},"PeriodicalIF":0.0,"publicationDate":"2005-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25298825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A novel myocardial motion estimation algorithm for ultrasonic image using optimal window size]. [一种基于最优窗口大小的超声图像心肌运动估计算法]。
航天医学与医学工程 Pub Date : 2005-06-01
Yong Jiang, Jing Bai
{"title":"[A novel myocardial motion estimation algorithm for ultrasonic image using optimal window size].","authors":"Yong Jiang,&nbsp;Jing Bai","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To establish a novel speckle tracking algorithm for estimating myocardial motion.</p><p><strong>Method: </strong>A search method was proposed to find the optimal window size for image matching. Simulation and clinical experiment were conducted to demonstrate the validity of this algorithm.</p><p><strong>Result: </strong>The optimal window size for image matching was determined using this algorithm. Correct speckle tracking could be fulfilled with the algorithm proposed.</p><p><strong>Conclusion: </strong>The method proposed in this paper is effective for speckle tracking.</p>","PeriodicalId":63677,"journal":{"name":"航天医学与医学工程","volume":"18 3","pages":"201-5"},"PeriodicalIF":0.0,"publicationDate":"2005-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25298823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effects of silverionized drinking water on lipids metabolism in tail-suspended rats]. [银离子饮用水对尾悬大鼠脂质代谢的影响]。
航天医学与医学工程 Pub Date : 2005-06-01
De-bing Zhu, Ji-ming Huang, Zhi-xia Li, Jian-wu Hong, Shu-min Bai, San-feng Chen
{"title":"[Effects of silverionized drinking water on lipids metabolism in tail-suspended rats].","authors":"De-bing Zhu,&nbsp;Ji-ming Huang,&nbsp;Zhi-xia Li,&nbsp;Jian-wu Hong,&nbsp;Shu-min Bai,&nbsp;San-feng Chen","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To study the effect of silverionized drinking water on erythrocyte membrane fluidity, serum lipids and vascular endothelial cells in tail-suspended rats.</p><p><strong>Method: </strong>Thirty male SD rats were randomly divided into ground control group (GC), simulated weightlessness control group (SC), simulated weightlessness and silverionized water drinking group (SS). Number of circulating endothelial cells (CEC), serum lipids and erythrocyte membranes fluidity was measured on the 21st day of tail suspension.</p><p><strong>Result: </strong>Levels of serum TC, TG, HDL-C, HDL-C/TC and erythrocyte membrane fluidity in SC rats were significantly lower than those in GC rats; LDL-C/HDL-C ratio and number of CEC in SC rats were markedly higher than those in GC rats. Levels of serum TC, LDL-C and LDL-C/HDL-C in SS rats were higher than those in SC rats; HDL-C/TC ratio and erythrocyte membrane fluidity in SS rats were lower than those in SC rats.</p><p><strong>Conclusion: </strong>Drinking silverionized water has a negative effect on lipid metabolism in tail-suspended rats.</p>","PeriodicalId":63677,"journal":{"name":"航天医学与医学工程","volume":"18 3","pages":"161-4"},"PeriodicalIF":0.0,"publicationDate":"2005-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25300069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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