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17th International Photodynamic Association World Congress最新文献

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Design and evaluation of applicators for photodynamic therapy of oral cavity tumors in low resource settings (Conference Presentation) 低资源环境下口腔肿瘤光动力治疗应用器的设计与评价(会议报告)
17th International Photodynamic Association World Congress Pub Date : 2019-08-14 DOI: 10.1117/12.2525860
Amjad P. Khan, S. Mallidi, Hui Liu, L. Daly, Grant Rudd, M. Hussain, Shakir Khan, S. Siddiqui, S. Hasan, K. Akhtar, S. Siddiqui, M. August, M. Troulis, Filip Cuckov, J. Celli, T. Hasan
{"title":"Design and evaluation of applicators for photodynamic therapy of oral cavity tumors in low resource settings (Conference Presentation)","authors":"Amjad P. Khan, S. Mallidi, Hui Liu, L. Daly, Grant Rudd, M. Hussain, Shakir Khan, S. Siddiqui, S. Hasan, K. Akhtar, S. Siddiqui, M. August, M. Troulis, Filip Cuckov, J. Celli, T. Hasan","doi":"10.1117/12.2525860","DOIUrl":"https://doi.org/10.1117/12.2525860","url":null,"abstract":"","PeriodicalId":6365,"journal":{"name":"17th International Photodynamic Association World Congress","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83460295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dosimetric considerations for intra cavity photodynamic therapy (Conference Presentation) 腔内光动力治疗的剂量学考虑(会议报告)
17th International Photodynamic Association World Congress Pub Date : 2019-08-14 DOI: 10.1117/12.2528021
R. V. Veen, R. Boumans, Tessa van Doeveren, P. Schreuder, Maarten J. A. Alphen, F. Heijden, B. Tan, Baris Karakullukҫu
{"title":"Dosimetric considerations for intra cavity photodynamic therapy (Conference Presentation)","authors":"R. V. Veen, R. Boumans, Tessa van Doeveren, P. Schreuder, Maarten J. A. Alphen, F. Heijden, B. Tan, Baris Karakullukҫu","doi":"10.1117/12.2528021","DOIUrl":"https://doi.org/10.1117/12.2528021","url":null,"abstract":"","PeriodicalId":6365,"journal":{"name":"17th International Photodynamic Association World Congress","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73563335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new platform technology RuVaCare, an extracorporeal anti-cancer vaccine is efficient in breaking immune barrier to target cancer cells (Conference Presentation) 一个新的平台技术RuVaCare，一种体外抗癌疫苗，有效地打破免疫屏障，靶向癌细胞(会议报告)
17th International Photodynamic Association World Congress Pub Date : 2019-08-14 DOI: 10.1117/12.2526627
L. Lilge, M. A. Munegowda, A. Mandel, R. Dumoulin-White
{"title":"A new platform technology RuVaCare, an extracorporeal anti-cancer vaccine is efficient in breaking immune barrier to target cancer cells (Conference Presentation)","authors":"L. Lilge, M. A. Munegowda, A. Mandel, R. Dumoulin-White","doi":"10.1117/12.2526627","DOIUrl":"https://doi.org/10.1117/12.2526627","url":null,"abstract":"Even though a patient has a good immune system, tumors are shielded from it, because tumors grow by suppressing the host’s immune-response by various mechanisms. They are keeping their local microenvironment immune suppressed by producing immune suppressive cytokines like IL-10 and TGF-b, express immune checkpoint ligands like Programmed Death Ligand 1 (PDL1), and harbor immune suppressive cells like Tregs and MDSCs. To overcome these barriers a stronger anti-tumour immune-response is essential. We evaluated a whole cell vaccine with extracorporeal Rutherrin®-PDT treated cancer cells (RuVaCareTM) to break the suppressive barrier in the RG2-glioblastoma model. Rutherrin®-PDT induced strong immunogenic cell death (ICD) in glioblastoma cells in-vitro. RuVaCareTM supernatants showed significantly higher level of extracellular ATP, which is known to induce recruitment of antigen presenting cells (APCs) and their activation by eliciting an effective anti-tumour immune-response. Extracellular calreticulin (CRT) is one of the hallmarks of ICD; its expression went up in more than 85% cells undergoing Rutherrin®-PDT mediated cell death. There was a close to 10 times increase in expression of HSP 70 in RuVaCareTM. Immunostimulatory cytokines IFNa, IL-1b and GMCSF expression is high in the RuVaCareTM. In-vivo efficacy of the RuVaCare™ was evaluated in orthotopic RG2 rat glioblastoma model. There was a significant increase (~43% with 2-time vaccine and 87% in the 6-time vaccine) in survival in the RuVaCare™ vaccinated groups compared to unvaccinated controls. Increased intratumoral CD8+T-cell numbers are shown to be correlated with increased survival in glioblastoma rats, with RuVaCare™ there was a significant increase in the number of CD8+T-cells.","PeriodicalId":6365,"journal":{"name":"17th International Photodynamic Association World Congress","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87534930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The mechanisms of bacterial inactivation via MB-APDT avoid drug resistance (Conference Presentation) MB-APDT细菌灭活机制避免耐药性(会议报告)
17th International Photodynamic Association World Congress Pub Date : 2019-08-14 DOI: 10.1117/12.2526355
C. Sabino, M. Baptista, M. Ribeiro, N. Lincopán
{"title":"The mechanisms of bacterial inactivation via MB-APDT avoid drug resistance (Conference Presentation)","authors":"C. Sabino, M. Baptista, M. Ribeiro, N. Lincopán","doi":"10.1117/12.2526355","DOIUrl":"https://doi.org/10.1117/12.2526355","url":null,"abstract":"","PeriodicalId":6365,"journal":{"name":"17th International Photodynamic Association World Congress","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88787787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Photodynamic nanomedicine synchronizes cytotoxic and molecular therapies to suppress multiple treatment escape pathways (Conference Presentation) 光动力纳米医学同步细胞毒和分子疗法抑制多种治疗逃逸途径(会议报告)
17th International Photodynamic Association World Congress Pub Date : 2019-08-14 DOI: 10.1117/12.2526045
Bryan Q. Spring
{"title":"Photodynamic nanomedicine synchronizes cytotoxic and molecular therapies to suppress multiple treatment escape pathways (Conference Presentation)","authors":"Bryan Q. Spring","doi":"10.1117/12.2526045","DOIUrl":"https://doi.org/10.1117/12.2526045","url":null,"abstract":"","PeriodicalId":6365,"journal":{"name":"17th International Photodynamic Association World Congress","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88387332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The scientific basis of photochemical internalization (PCI) (Conference Presentation) 光化学内化(PCI)的科学基础(会议报告)
17th International Photodynamic Association World Congress Pub Date : 2019-08-14 DOI: 10.1117/12.2527907
K. Berg
{"title":"The scientific basis of photochemical internalization (PCI) (Conference Presentation)","authors":"K. Berg","doi":"10.1117/12.2527907","DOIUrl":"https://doi.org/10.1117/12.2527907","url":null,"abstract":"","PeriodicalId":6365,"journal":{"name":"17th International Photodynamic Association World Congress","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78512329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implantable electronic device and tissue-adhesive nanosheets can introduce photodynamic therapy into inside the body (Conference Presentation) 植入式电子设备和组织黏附纳米片可将光动力疗法引入体内(会议报告)
17th International Photodynamic Association World Congress Pub Date : 2019-08-14 DOI: 10.1117/12.2528044
I. Kirino, K. Yamagishi, I. Takahashi, H. Amano, Takeoka Shinji, S. Uemoto, T. Fujie, Y. Morimoto
{"title":"Implantable electronic device and tissue-adhesive nanosheets can introduce photodynamic therapy into inside the body (Conference Presentation)","authors":"I. Kirino, K. Yamagishi, I. Takahashi, H. Amano, Takeoka Shinji, S. Uemoto, T. Fujie, Y. Morimoto","doi":"10.1117/12.2528044","DOIUrl":"https://doi.org/10.1117/12.2528044","url":null,"abstract":"","PeriodicalId":6365,"journal":{"name":"17th International Photodynamic Association World Congress","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78925035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phase I clinical study for validation of photochemical internalisation (fimaVacc): a novel technology for enhancing cellular immune responses important for therapeutic effect of peptide- and protein-based vaccines (Conference Presentation) 验证光化学内化(fimaVacc)的I期临床研究:一种增强细胞免疫反应的新技术，对肽和蛋白基疫苗的治疗效果很重要(会议报告)
17th International Photodynamic Association World Congress Pub Date : 2019-08-14 DOI: 10.1117/12.2526042
A. Høgset, A. Nedberg, V. Edwards, M. Håkerud, H. Olivecrona, T. Otterhaug
{"title":"Phase I clinical study for validation of photochemical internalisation (fimaVacc): a novel technology for enhancing cellular immune responses important for therapeutic effect of peptide- and protein-based vaccines (Conference Presentation)","authors":"A. Høgset, A. Nedberg, V. Edwards, M. Håkerud, H. Olivecrona, T. Otterhaug","doi":"10.1117/12.2526042","DOIUrl":"https://doi.org/10.1117/12.2526042","url":null,"abstract":"","PeriodicalId":6365,"journal":{"name":"17th International Photodynamic Association World Congress","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76432005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Real-time GPU accelerated hyperspectral unmixing (Conference Presentation) 实时GPU加速高光谱解混(会议报告)
17th International Photodynamic Association World Congress Pub Date : 2019-08-14 DOI: 10.1117/12.2527922
Eric M. Kercher, Julia Tatz, Q. Fang, Bryan Q. Spring
{"title":"Real-time GPU accelerated hyperspectral unmixing (Conference Presentation)","authors":"Eric M. Kercher, Julia Tatz, Q. Fang, Bryan Q. Spring","doi":"10.1117/12.2527922","DOIUrl":"https://doi.org/10.1117/12.2527922","url":null,"abstract":"","PeriodicalId":6365,"journal":{"name":"17th International Photodynamic Association World Congress","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73609062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Capecitabine (Xeloda) enhanced photodynamic therapy for treatment of breast cancer and its metastases in a murine breast tumor model (Conference Presentation) 卡培他滨(希罗达)增强光动力疗法治疗乳腺癌及其在小鼠乳腺肿瘤模型中的转移(会议报告)
17th International Photodynamic Association World Congress Pub Date : 2019-08-14 DOI: 10.1117/12.2525564
S. Anand, Anton Yasinchak, Taylor A. Bullock, Mukul Govande, E. Maytin
{"title":"Capecitabine (Xeloda) enhanced photodynamic therapy for treatment of breast cancer and its metastases in a murine breast tumor model (Conference Presentation)","authors":"S. Anand, Anton Yasinchak, Taylor A. Bullock, Mukul Govande, E. Maytin","doi":"10.1117/12.2525564","DOIUrl":"https://doi.org/10.1117/12.2525564","url":null,"abstract":"","PeriodicalId":6365,"journal":{"name":"17th International Photodynamic Association World Congress","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73623273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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