2005 Asian Conference on Sensors and the International Conference on New Techniques in Pharmaceutical and Biomedical Research最新文献

{"title":"COVID‐19 Pandemic: Management and Challenges","authors":"Parisa Saberi-Hasanabadi, H. Mohammadi","doi":"10.18502/pbr.v7i2.7359","DOIUrl":"https://doi.org/10.18502/pbr.v7i2.7359","url":null,"abstract":"Background: Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‑CoV‑2). The outbreak was first identified in Wuhan, China, in December 2019. \u0000Objectives: This review gives a bird’s-eye view of the COVID-19 pandemic and its various effects on human society. Since knowledge about this virus is rapidly evolving, readers are urged to update themselves regularly. \u0000Methods: In this review, our searching was performed on international databases of Embase, ScienceDirect, Scopus, PubMed, and Web of Science (ISI) from October 2019 to June 2020. \u0000Results: Most patients infected with COVID‑19 have mild symptoms. Approximately 15% of patients have severe pneumonia, and about 5% acute distress syndrome or organ failure. In the absence of definitive treatment and vaccines, the most effective measure is to prevent infection, particularly in those at high risk of taking the severe form of the disease with adverse outcomes. Pharmacotherapy is essentially supportive; the role of antiviral agents is yet to be established. The commonest drugs used in treating this viral disease are tocilizumab, remdesivir, favipiravir, and camostat mesilate. Also, drugs related to malaria, AIDS, and Ebola, such as hydroxychloroquine, are widely used. Based on physical examinations alone, it is impossible to comment with certainty in mild cases of the disease. Accordingly, a wide range of methods is used for diagnosing and treating the disease. Various variables in reducing the severity of the epidemic and the effects of the virus require special management at the national, regional, and global levels. \u0000Conclusion: This review summarizes the latest findings in safety, management, and public services related to the COVID-19 virus epidemic.","PeriodicalId":6323,"journal":{"name":"2005 Asian Conference on Sensors and the International Conference on New Techniques in Pharmaceutical and Biomedical Research","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80508041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Case Series of Gastrointestinal Symptoms in Patients With Novel Coronavirus 2019 Infection","authors":"Hamideh Abbaspour kasgari, A. Shabani, H. Fakheri, Parnian Mohammadzadeh","doi":"10.18502/pbr.v7i2.7366","DOIUrl":"https://doi.org/10.18502/pbr.v7i2.7366","url":null,"abstract":"Background: Various digestive symptoms have been frequently reported in a significant portion of patients infected with the virus since the outbreak of Coronavirus Disease 2019 (COVID-19). Most patients with COVID-19 have a fever accompanied by respiratory signs and symptoms, such as cough and dyspnea. We present 36 cases with a chief complaint of Gastrointestinal (GI) symptoms along with respiratory symptoms. In this study, we aimed at investigating the prevalence and outcomes of COVID-19 patients with digestive symptoms. \u0000Methods: A variety of observed GI symptoms included nausea and vomiting (72.2%), diarrhea (25%), abdominal pain (19.4%), loss of appetite (14%), and anosmia (14%). The most nonGI symptoms were dyspnea (66.7%), fever (66.7%), dry cough (58.3%), myalgia (52.4%), and others. Six patients (16.6%) were critically ill, 7 (19.4%) were in stable condition, and 23 patients (64%) showed moderate symptoms. Among the patients, 7 (19.5%) needed critical care and were admitted to ICU. Leucopenia, lymphopenia, and elevated acute-phase proteins were other features observed in these patients. The most common antiviral regimen was hydroxychloroquine and oseltamivir. Finally, 32 patients (89%) were discharged, and 4 (11%) died. \u0000Conclusion: This case series study highlights that patients with COVID-19 are prone to GI symptoms along with fever and respiratory symptoms. Patients may even present with digestive symptoms and without any respiratory symptoms. Hence, clinicians should pay more attention to these patients and help diagnose COVID-19 earlier to start prompt treatment before the occurrence of severe disease.","PeriodicalId":6323,"journal":{"name":"2005 Asian Conference on Sensors and the International Conference on New Techniques in Pharmaceutical and Biomedical Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86438130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Study of Apigenin Content and Antioxidant Potential of CosmosBipinnatus Transgenic Root Culture","authors":"Soroush Bijani, Z. Gharari, A. Ahmadnia, H. Danafar, A. Sharafi","doi":"10.18502/pbr.v7i2.7361","DOIUrl":"https://doi.org/10.18502/pbr.v7i2.7361","url":null,"abstract":"Background: Flavonoid-derived components have been studied for their therapeutic properties. \u0000Objectives: Apigenin has shown remarkable antioxidant and anti-inflammatory features, so we should have a reliable source of apigenin. \u0000Methods: In this study, we used high-performance liquid chromatography method to compare the amount of apigenin in flower, root, leaf, and stem of three varieties of osmos bipinnatus, i.e., ‘Dazzler,’ ‘Xanthos,’ ‘Sensation Pinkie’, and in transgenic root culture of C. bipinnatus ‘Dazzler’. Besides, the antioxidant activity of C. bipinnatus ‘Dazzler’ transgenic root culture was evaluated using Ferric Reducing Antioxidant Power (FRAP) assay. \u0000Results: Dazzler variety flowers showed the highest recovery of apigenin with 0.799 mg/100 mg Dry Weight (DW). However, the Sensation pinkie variety leafs had the lowest recovery with 0.089 mg/100mg. Apigenin content in transformed roots (0.797 mg/100 mg DW) of C. bipinnatus ‘Dazzler’ was significantly higher than non-transformed roots (0.42 mg/100 mg DW). The ethanolic extract of hairy root showed the FRAP value of 668.1 µM Fe2+/mg that was comparatively more than the wild root FRAP value (426.2 µM Fe2+/mg). \u0000Conclusion: In conclusion, the presence of apigenin in high amounts in hairy root cultures of C. bipinnatus ‘Dazzler’ indicates its great potential for the future pharmaceutical industry.","PeriodicalId":6323,"journal":{"name":"2005 Asian Conference on Sensors and the International Conference on New Techniques in Pharmaceutical and Biomedical Research","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89249392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibitory Effects of Salinispora-derived Metabolites Against Multidrug Resistance: An In-silico Study","authors":"Morteza Ghandadi","doi":"10.18502/pbr.v7i1.7354","DOIUrl":"https://doi.org/10.18502/pbr.v7i1.7354","url":null,"abstract":"Background: Multi Drug Resistance (MDR) is known to defeat most chemotherapies as one of the main anticancer strategies. The role of overexpression or overactivation of ATPBinding Cassette (ABC) transporters, especially P-glycoprotein (P-gp), in the development of chemotherapy has long been demonstrated. Salinispora is a marine actinomycete genus known for the production of novel bioactive metabolites. \u0000Objectives: In this study, the potential of Salinispora derived metabolites as inhibitor of ATPbinding cassette (ABC) transports have been investigated using in-silico approaches. \u0000Methods: Physicochemical, pharmacokinetic and drug likeness of the Salinispora derived metabolites have been analyzed using SwissADME server. This was accompanied by the employment of docking strategy to evaluate anti-MDR potential of the metabolites using P-gp, Breast Cancer Resistance Protein (BCRP) and Multidrug Resistance Protein 1 (MRP-1) as target proteins. \u0000Results: Nineteen metabolites were found to have demonstrated appropriate physicochemical, pharmacokinetic, and drug-likeness properties and were involved in the docking studies. Based on docking studies, saliniquinones, cyclomarazine, and cyanosporoside A demonstrated ABC transporters inhibitory potential. \u0000Conclusion: Our results suggest that further in vivo and in vitro studies on anti-MDR effects of Salinispora-derived metabolites are warranted.","PeriodicalId":6323,"journal":{"name":"2005 Asian Conference on Sensors and the International Conference on New Techniques in Pharmaceutical and Biomedical Research","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89482261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Doctors Perception of the Use of Hydroxychloroquine as Prophylaxis for COVID-19 Infection","authors":"Proteesh Rana, M. Ghadlinge, Pratap Singh, Rakhamaji D. Chandane, A. Khanna","doi":"10.18502/pbr.v7i2.7362","DOIUrl":"https://doi.org/10.18502/pbr.v7i2.7362","url":null,"abstract":"Background: The National Task force constituted by the Indian Council of Medical Research (ICMR) and various International agencies has recommended the use of Hydroxychloroquine (HCQ) as prophylaxis for Coronavirus Disease 2019 (COVID-19). This measure was taken because of the urgent need to protect high-risk individuals like Health Care Workers (HCW) from contracting COVID-19. \u0000Objectives: This study aimed to assess the awareness, attitudes, and practices on using HCQ as prophylaxis to prevent COVID-19 infection. \u0000Methods: A cross-sectional study was conducted among the doctors working in Dr RML Hospital, New Delhi, India, a tertiary care public hospital involved in the care of COVID-19 patients. The invitation to participate was electronically circulated, and the consenting participants were allowed to access an online survey. The survey had a total of 23 questions that were designed to understand the awareness, perception, and practices of doctors regarding the use of HCQ as prophylaxis in COVID-19. \u0000Results: About 147 doctors participated in this survey. The major source of knowledge regarding HCQ prophylaxis was quoted as regulatory agencies (44%), particularly ICMR, and the main indication was reported as being a healthcare worker (60%). Most of the participants (91%) believed that the HCQ effect is not clear and felt more scientific data regarding the use of HCQ as prophylaxis for COVID-19. But many doctors (51%) still recommend using HCQ to their colleagues. \u0000Conclusion: In this study, we observed that most doctors were aware of the recommendations regarding the HCQ prophylaxis in COVID-19 and had good adherence to therapy but felt the need for more concrete scientific evidence for using HCQ.","PeriodicalId":6323,"journal":{"name":"2005 Asian Conference on Sensors and the International Conference on New Techniques in Pharmaceutical and Biomedical Research","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84343836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Susceptibility and Resistance of Human Infectious Bacteria and Identification of Bioactive Compounds in Pistacia atlantica, Cassia absus, and Quercus persica","authors":"M. Alamholo, Yosof Amraie","doi":"10.18502/pbr.v7i2.7363","DOIUrl":"https://doi.org/10.18502/pbr.v7i2.7363","url":null,"abstract":"Background: The antimicrobial activity of plants has long been considered an effective mechanism for controlling pathogenic microorganisms. \u0000Objectives: This study aimed to identify phytochemical compounds of the seed extracts from ethnomedicinal plants of Pistacia atlantica, Cassia absus, and Quercus persica with Gas Chromatography-Mass Spectrometry (GC-MS) and investigation of their antibacterial and antioxidant activities. \u0000Methods: The seeds were collected from Lorestan Province, Iran. Their antibacterial and antiradical activities were analyzed by disk-diffusion and 2,2-diphenyl-1-picrylhydrazyl assays, respectively. Ethanol (96%), methanol (80%), and distilled water extracts were obtained by the maceration method. The methanol extract was used for the analysis of chemical compositions. \u0000Results: About 40, 31, and 8 compounds were identified by GC-MS in the seeds of C. absus, P. atlantica, and Q. persica, respectively. Results indicated that 2,4-di-tert-butylphenol (36.043%) and tetradecanoic acid (4.92%) were dominated in the seed extracts of C. absus. However, germacyclopetene (38.119%) and 1,2,3-benzenetriol (8.115%) were dominated in the seed extracts of P. atlantica. Furthermore, 5H-tetrazole-5-thione, 1,4-dihydro-1,4-dimethy (38.505%), and tetradecanoic acid (30.546%) were dominated in the seed extracts of Q. persica. The highest inhibitory activity against Micrococcus luteus was observed on the methanol extract of C. absus with ascorbic acid. A significant difference was observed between the Inhibitory Concentration (IC50) values of methanol extract of C. absus with ascorbic acid. \u0000Conclusion: Because of the presence of antimicrobial compounds in the tested ethnomedicinal plants, they can be used to synthesize new antimicrobial drugs in medicinal and pharmaceutical sciences.","PeriodicalId":6323,"journal":{"name":"2005 Asian Conference on Sensors and the International Conference on New Techniques in Pharmaceutical and Biomedical Research","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78030870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"L-arginine Ameliorated Mitochondrial Oxidative Damage Induced by Sub-chronic Exposure to Cadmium in Mice Kidney","authors":"F. Shaki, Melika Teymoori, F. Motafeghi, Nasibeh Hemmati, M. Arab-Nozari","doi":"10.18502/pbr.v7i2.7360","DOIUrl":"https://doi.org/10.18502/pbr.v7i2.7360","url":null,"abstract":"Background:Cadmium is a heavy metal that can cause various injuries in the body, including nephrotoxicity. L-Arginine is a metal chelator that can prevent oxidative damage caused by oxygen free radicals. \u0000Objectives:This study aimed to investigate the effect of L-arginine in inhibiting mitochondrial toxicity induced by subchronic cadmium exposure in the kidney of male mice. \u0000Methods: A total of 42 male mice were randomly divided into six groups (n=6): control (normal saline), cadmium (2 mg/kg), cadmium (2 mg/kg) plus three doses of L-arginine (50, 100, and 200 mg/kg) and finally cadmium (2 mg/kg) plus vitamin C (500 mg/kg). After 42 days, the animals were anesthetized with ketamine/xylazine. Their kidney tissues were removed, and mitochondrial fractions were isolated. Oxidative stress factors and mitochondrial damage parameters (MTT, swelling, and mitochondrial membrane potential) were measured in renal isolated mitochondria. Also, evaluation of Blood Urea Nitrogen (BUN) and Creatinine (Cr) tests were done. \u0000Results: Significant rise in BUN and Cr were observed in cadmium-treated mice (P<0.05). Cadmium enhanced oxidative stress in the kidney via increasing lipid peroxidation and oxidation of protein and glutathione. It caused significant mitochondrial dysfunction, mitochondrial membrane potential collapse, and swelling in isolated mitochondria (P<0.05). L-Arginine significantly ameliorated cadmium-induced oxidative stress and mitochondrial damage (P<0.05). Furthermore, a significant reduction in serum BUN and Cr were observed in L-arginine received group (P<0.05). \u0000Conclusion: The results showed that L-arginine has significant protective effects against cadmium-induced renal toxicity in male mice.","PeriodicalId":6323,"journal":{"name":"2005 Asian Conference on Sensors and the International Conference on New Techniques in Pharmaceutical and Biomedical Research","volume":"483 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78124671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poisoning and its Management in Healthcare Facilities in Lagos State, Nigeria","authors":"A. Joda, O. Ajetunmobi, O. Olugbake","doi":"10.18502/pbr.v7i1.7352","DOIUrl":"https://doi.org/10.18502/pbr.v7i1.7352","url":null,"abstract":"Background: Poisons are chemical substances that produce harmful effects on the body. About 0.3 million people die annually from poisoning. Poisons are produced by animals, plants, microorganisms, and food contamination. Poisoning is a global public health problem, especially in children and teenagers and healthcare providers ought to provide protocols for its management. \u0000Objectives: The main aim of this study was to document the mode, knowledge of antidotes, and management of poisoning by healthcare providers in selected community pharmacies and hospitals in Lagos state. \u0000Methods: This study was a descriptive cross-sectional study. The study data were collected using questionnaires administered to 112 providers in selected community pharmacies and hospitals in Lagos state. The obtained data were collated and analyzed using SPSS version 20.0. Results were presented as frequency tables and charts. \u0000Results: A response rate of 85.7% was achieved. The most common mode of poisoning was accidental (89% and 68% among pharmacists and physicians, respectively) and the highest incidence was among children 0-5 years old (41.5% and 48.3% among pharmacists and physicians, respectively). Management was mainly via gastric decontamination with activated charcoal in pharmacies and supportive care in the hospitals. Knowledge and availability of antidotes and management of poisoning were poor. \u0000Conclusion: Management of poisoning was generally inadequate and the prominence of a poison control center was recognized. The establishment of poison control centers in healthcare facilities and the organization of updated lectures for healthcare providers will go a long way to improving poisoning management in the state.","PeriodicalId":6323,"journal":{"name":"2005 Asian Conference on Sensors and the International Conference on New Techniques in Pharmaceutical and Biomedical Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74495043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemorrhagic Events in Patients Receiving Heparin or Enoxaparin in Combination With Oral Antithrombotics, NSAIDs, and Antiplatelet Medications: A Multi-Center Case-Series Study","authors":"A. Ghanbarzamani, Aida Sefidani Forough, J. Salamzadeh, F. Fahimi","doi":"10.18502/pbr.v7i2.7364","DOIUrl":"https://doi.org/10.18502/pbr.v7i2.7364","url":null,"abstract":"Background: Hemorrhagic events are amongst the significant adverse effects of injectable anticoagulants such as heparin and enoxaparin. This undesirable effect needs close monitoring of their use for clinically relevant drug-drug interactions. \u0000Objectives: To study the rate of hemorrhagic events, the anatomical site, and the severity of the bleeding in patients receiving heparin or enoxaparin in combination with clopidogrel, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), and warfarin. \u0000Methods: We designed a prospective, multi-center, case-series study. Patients admitted to two teaching hospitals who received either an NSAID, or warfarin, or clopidogrel were evaluated. Any hemorrhagic event was recorded by Yellow Card Scheme. Also, the Naranjo scale was utilized for causality assessment.Results: A total of 123 patients were eligible for inclusion. They were admitted between November 2014 and April 2015. Sixty-five patients (52.5%) received heparin and 58 patients (47.2%) received enoxaparin. Of 123 patients, 115 patients (93.5%) received aspirin, 69 (56.1%) warfarin, 34 (27.6%) an antiplatelet medication, and 121 (98.4%) NSAIDs in combination with heparin or enoxaparin. Overall, 26 cases (21.1%) of the hemorrhagic incident were reported, of whom six cases (4.9%) were categorized as major bleeding. Patients receiving heparin constituted the largest proportion among all 26 hemorrhagic incidents (57.7%). All patients with the hemorrhagic incident had aspirin in their medication regimen, while 19 patients (73.0%) were concomitantly receiving warfarin as well. Hematuria (46.2%), hematoma in the injection site (38.5%), and hematoma (34.6%) were the top three types of hemorrhagic events. In Naranjo scale analysis, 19 patients scored more than 9 points, indicating a definite Adverse Drug Reaction (ADR) causality. Moreover, seven patients scored 5 to 8, affirming a possible association with ADR. \u0000Conclusion: The risk of hemorrhagic can be influenced by undesirable drug-drug interactions. Close monitoring of high-risk patients is advised to prevent adverse hemorrhagic reactions. Further studies to detect the explanatory factors associated with the hemorrhagic events are recommended. \u0000 ","PeriodicalId":6323,"journal":{"name":"2005 Asian Conference on Sensors and the International Conference on New Techniques in Pharmaceutical and Biomedical Research","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78943002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Inclusive Quality Management on the Educational Accreditation Results of the Educational Centers of Mazandaran University of Medical Sciences in 2015-2018","authors":"Roya Malekzadeh, F. Amuei, Elahe Mahmoudi, G. Abedi, H. Mohammadi","doi":"10.18502/pbr.v7i1.7353","DOIUrl":"https://doi.org/10.18502/pbr.v7i1.7353","url":null,"abstract":"Background: The Deming model is an effective method for comprehensive quality management. \u0000Objectives: This study aimed to investigate the effect of inclusive quality management on the educational accreditation results of the educational hospitals in the Mazandaran Province, Iran. \u0000Methods: This interventional study was conducted in 5 hospitals. In this study, the Deming cycle validation model was employed. This model, which is based on the checklist for the educational centers of the Ministry of Health and Medical Education, has 91 benchmarks for 81 standards. Descriptive statistical methods (Wilcoxon and Friedman nonparametric tests) were used to analyze the data. \u0000Results: A significant difference was observed among the accreditation scores of the hospitals before and after the intervention (P<0.05). The accreditation score obtained by the educational centers improved by 41.1, 37, 15.7, 53.2, and 49.2 units. Besides, the intervention outcomes in all areas of accreditation, except facilities management, space, facilities, equipment, and resources, were significantly different. \u0000Conclusion: The use of the Deming cycle has proved effective in performing the educational accreditation of the centers, which can be achieved with continuous and proper implementation. This study can help improve the standards of education of the educational centers.","PeriodicalId":6323,"journal":{"name":"2005 Asian Conference on Sensors and the International Conference on New Techniques in Pharmaceutical and Biomedical Research","volume":"1992 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82377231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}