中华儿科杂志最新文献

{"title":"[Clinical characteristics and prognosis of pediatric precursor lymphoid neoplasms with KMT2A gene rearrangement].","authors":"Y Y Zhu, P Ma, Y Y He, J W Zhou, S Huang, Y F Wang, Y T Su, R D Zhang, Y N Mao","doi":"10.3760/cma.j.cn112140-20251229-01155","DOIUrl":"10.3760/cma.j.cn112140-20251229-01155","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the clinical characteristics and prognostic factors of pediatric precursor lymphoid neoplasms with KMT2A gene rearrangement. <b>Methods:</b> In this retrospective cohort study, clinical data of 47 children with KMT2A gene rearrangement precursor lymphoid neoplasms diagnosed at the Children's Hospital Affiliated to Zhengzhou University from January 2018 to November 2024 were collected, so as to describe their clinical characteristics. According to whether hematopoietic stem cell transplantation (HSCT) was performed during first complete remission (CR1), children were divided into CR1 transplantation group and CR1 chemotherapy group, survival rates comparison and prognostic factor analysis were performed between two groups. For relapsed children in the CR1 chemotherapy group, they were further subdivided into a transplantation salvage group and a chemotherapy salvage group based on salvage therapy modality, and post-relapse survival rates were compared between the two subgroups. Survival rates were calculated using the Kaplan-Meier method and compared using the log-rank test. Prognostic factors were analyzed using the Cox proportional hazards regression model. <b>Results:</b> Among the 47 patients, there were 27 males and 20 females, with the age of 0.8 (0.4, 2.4) years. B-cell acute lymphoblastic leukemia accounted for 85% (40 cases). The initial white blood cell count was 89×10⁹ (27×10⁹, 302×10⁹)/L. Central nervous system leukemia was diagnosed in 10 children(22%, 46 children had central nervous system assessment). A total of 43 children were included in the efficacy evaluation, with a follow-up of 30.1 (13.8, 47.7) months. The 3-year overall survival and event-free survival (EFS) rates were (68.2±7.3) % and (51.7±8.0) %, respectively. The CR1 transplantation group (17 children) had significantly better 3-year overall survival and EFS rates than the CR1 chemotherapy group (26 children)(100.0% <i>vs.</i> (47.2±10.1) %, (84.7±10.3) % <i>vs.</i> (29.6±9.1) %, <i>χ</i>²=12.68 and 16.03, both <i>P</i><0.001). The transplantation salvage group (4 children) had a higher 18-month overall survival rate than the chemotherapy salvage group (14 children) (100.0% <i>vs.</i> (8.9±8.4)%, <i>χ</i>²=10.07, <i>P</i>=0.002). Multivariate analysis showed that negativity of minimal residual disease detected by quantitative real-time PCR (qPCR-MRD) at week 12 of induction therapy (<i>HR</i>=0.29, 95%<i>CI</i> 0.10-0.83, <i>P</i>=0.022) and HSCT (<i>HR</i>=0.15, 95%<i>CI</i> 0.05-0.44, <i>P</i><0.001) were both independent protective factors for EFS. <b>Conclusion:</b> Pediatric KMT2A gene rearrangement precursor lymphoid neoplasms are clinically highly aggressive and have a poor prognosis, but negative qPCR-MRD at week 12 of induction therapy and HSCT are independent protective factors for EFS.</p>","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"924-929"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Transcatheter closure of intracristal ventricular septal defect using eccentric occluders in 39 children].","authors":"T H Xia, Y Feng, W J Zhang, X R Lin, S Y Zhang, X Rong, R Z Wu","doi":"10.3760/cma.j.cn112140-20251226-01146","DOIUrl":"10.3760/cma.j.cn112140-20251226-01146","url":null,"abstract":"<p><p><b>Objective:</b> To evaluate the efficacy and clinical outcomes of transcatheter closure of intracristal ventricular septal defect (VSD) using an eccentric occluder. <b>Methods:</b> In this case series study, 39 children with intracristal VSD who underwent attempted transcatheter closure using an eccentric occluder at the Second Affiliated Hospital of Wenzhou Medical University from January 2011 to December 2021 were included. All children were regularly followed up at 1, 3, 6, 12, 24 and 36 months after the procedure. Echocardiography, electrocardiography and treadmill exercise testing were used for postoperative follow-up evaluation. The main outcomes included occlude morphology and position, residual shunt, valvular regurgitation, cardiac function, arrhythmia and postoperative exercise capacity. Comparisons among different follow-up time points were performed using the paired <i>t</i>-test or repeated-measures analysis of variance, Friedman test or Wilcoxon signed-rank test. <b>Results:</b> Device implantation was successful in 38 of 39 children (97%). One child underwent surgical repair because the aortic valve prolapse protruded into the VSD shunt orifice, making transcatheter closure unsuitable. No severe complications occurred after the procedure. Follow-up showed that residual shunt was observed in 7 children (18%) after the procedure and disappeared within 24 months of follow-up. Valvular regurgitation occurred in 9 children (24%) and did not worsen during follow-up; in 7children, valvular regurgitation disappeared within 36 months. Arrhythmia occurred in 6 children (16%), including incomplete right bundle branch block in 2 children and premature ventricular contractions in 4 children. Five children resolved within 12 months, and the remaining 1 child resolved by 36 months of follow-up. Compared with baseline, the Z scores of left ventricular end-diastolic diameters and left atrial diameters showed a progressive decrease during the first 1 to 6 months after transcatheter closure (both <i>P</i><0.05), and remained stable after 24 months. Right ventricular diameter and left ventricular ejection fraction showed no significant changes before and after the procedure (all <i>P</i>>0.05). A total of 20 children underwent treadmill exercise testing 1 year after the procedure, and 19 children (95%) had negative results. <b>Conclusion:</b> Transcatheter closure of intracristal VSD using an eccentric occluder is effective and feasible, with favorable safety and efficacy during short-and mid-term follow-up.</p>","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"936-940"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Role of immune resilience in pediatric infection research].","authors":"H M Liu, F Fang","doi":"10.3760/cma.j.cn112140-20260606-00441","DOIUrl":"10.3760/cma.j.cn112140-20260606-00441","url":null,"abstract":"","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"845-847"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Significance of the multi-pathogen surveillance of pediatric patients with acute respiratory infections in Beijing from 2024 to 2025].","authors":"Y C Sun, R N Zhu, Y Sun, Y T Zhou, Y Yao, Y L Feng, C Yan, G Q Zhang, X L Ma, J Yuan, C M Zhu, L Q Zhao","doi":"10.3760/cma.j.cn112140-20260120-00061","DOIUrl":"10.3760/cma.j.cn112140-20260120-00061","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To delineate the pathogen spectrum and epidemiological features of acute respiratory infections (ARI) among pediatric patients in Beijing during 2024-2025. &lt;b&gt;Methods:&lt;/b&gt; In this cross-sectional study, 1 435 children diagnosed with ARI were enrolled from outpatient, emergency, respiratory medicine, and critical care medicine department of Capital Center for Children's Health, Capital Medical University between July 2024 and June 2025. Respiratory specimens were collected and screened for 28 respiratory pathogens using multiplex real-time quantitative PCR. Specimens positive for influenza virus, respiratory syncytial virus (RSV), human metapneumovirus (HMPV), and human rhinovirus were further subtyped. Patients were categorized into influenza-like illness (ILI) and severe acute respiratory infection (SARI) groups. Positivity rates across different sources, visit periods, and age groups were compared using the chi-square test and Wilcoxon rank-sum test. &lt;b&gt;Results:&lt;/b&gt; Among the 1 435 children, there were 770 males and 665 females, with an age at presentation was 6.7 (4.4, 12.6) years. The total positive rate for the 28 pathogens was 80.5% (1 155/1 435). The ILI group comprised 1 040 cases (549 males, 491 females) with age at presentation was 6.8 (4.5, 12.8) years and the positive rate of 76.6% (797/1 040). Common viral pathogens included human rhinovirus 15.7% (163/1 040), human parainfluenza-virus (HPIV) 10.3% (107/1 040), and Influenza virus 7.1% (74/1 040), while common bacterial and atypical pathogens included &lt;i&gt;Mycoplasma pneumoniae&lt;/i&gt; (MP) 18.7% (194/1 040), &lt;i&gt;Haemophilus influenzae&lt;/i&gt; (HI) 18.4% (191/1 040), and &lt;i&gt;Streptococcus pneumonia&lt;/i&gt; (SP) 17.1% (178/1 040). The SARI group comprised 395 cases (221 males, 174 females) with age at presentation was 6.5 (4.0, 12.3) years and the positive rate of 90.6% (358/395). Common viral pathogens included human rhinovirus 17.2% (68/395), RSV 9.9% (39/395), and HPIV 7.1% (28/395), while common bacterial and atypical pathogens included MP 51.4% (203/395), SP 15.4% (61/395), and HI 13.4% (53/395). Co-detections of multiple pathogens accounted for 43.0% (497/1 155) of all positive cases. The positivity rates of RSV and MP in the SARI group were significantly higher than those in the ILI group (both &lt;i&gt;P&lt;/i&gt;&lt;0.001). RSV positive rate was the highest in children under 1 year of age, accounting for 15.3% (13/85), while MP positive rate was the highest in children aged 7 to 18 years, accounting for 38.1% (205/538). Typing results revealed that 96.5% (83/86) were typed to H1N1 among influenza virus A cases, while 58.3% (42/72) were genotyped as RSV-A ON1 among RSV cases, 86.3% (63/73) were subtyped to B2 among HMPV cases, and 45.0% (104/231) were typed to human rhinovirus-A among human rhinovirus cases. &lt;b&gt;Conclusion:&lt;/b&gt; The pathogen spectrum of pediatric patients with ARI in Beijing from 2024 to 2025 was characterized by the alternation or co-circulation of multiple bacteria a","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"887-892"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Advances in diagnosis and treatment for heart failure with preserved ejection fraction in children].","authors":"D Lu, Y Yin, Y X Yuan, B Pan, H C Sun, M Li, T W Lyu, J Tian","doi":"10.3760/cma.j.cn112140-20251215-01107","DOIUrl":"10.3760/cma.j.cn112140-20251215-01107","url":null,"abstract":"","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"965-968"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Expert consensus on clinical diagnosis and treatment of pediatric newly diagnosed Hodgkin lymphoma (2026)].","authors":"","doi":"10.3760/cma.j.cn112140-20260209-00127","DOIUrl":"10.3760/cma.j.cn112140-20260209-00127","url":null,"abstract":"","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"873-880"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical analysis of 9 children of B-cell acute lymphoblastic leukemia with MEF2D gene rearrangement].","authors":"X P Jia, A N Lian, Y S Zhang, J Luo, Y J Ren, X J Xu, S T Bai, G Y Sheng, C M Wang","doi":"10.3760/cma.j.cn112140-20251230-01163","DOIUrl":"10.3760/cma.j.cn112140-20251230-01163","url":null,"abstract":"<p><p><b>Objective:</b> To summarize the clinical characteristics, molecular genetic features, diagnosis and treatment of pediatric B-cell acute lymphoblastic leukemia (B-ALL) with myocyte enhancer factor 2D (MEF2D) gene rearrangement. <b>Methods:</b> In this case series study, clinical data of 9 children newly diagnosed B-ALL with MEF2D gene rearranged, admitted to the First Affiliated Hospital of Zhengzhou University from May 2020 to June 2025 were collected. The clinical characteristics, laboratory findings, treatment regimens, and outcomes of these patients were systematically analyzed. <b>Results:</b> A total of 9 chlidren were enrolled (3 boys and 6 girls), with the diagnostic age of 12.0 (11.0, 13.8) years. Five children initially presented with fever accompanied by arthralgia. Immunophenotyping revealed that 1 child was early precursor B-ALL and the remaining 8 children were common B-ALL. Uniformly high expression of CD38 and absence of cytoplasmic immunoglobulin M (cIgM) expression in all 9 children. Bone marrow smear examination demonstrated cytoplasmic vacuolization in 5 children. RNA sequencing detected 5 types of MEF2D gene fusion partners, including BCL9 gene in 4 children, FOXJ2 gene in 2 children, and 1 child each of DAZAP1 gene, SS18 gene, and ARNT gene. Heterozygous deletions of CDKN2A or CDKN2B gene were detected in 6 children, and 8 children exhibited concurrent gene variations. Induction therapy with the vincristine+daunorubicin+L-asparaginase+prednisone (VDLP) regimen was administered to all 9 children in accordance with＂the Clinical Practice Guideline for Childhood Acute Lymphoblastic Leukemia (2018)＂. At the end of induction remission therapy, minimal residual disease (MRD) assessed by flow cytometry were all negative (<0.01%) in all cases. One child was lost to follow-up during the maintenance phase. Three children experienced relapse and succumbed. The remaining 5 children were followed up until October 10, 2025, with 2 in disease-free survival and 3 still receiving regular treatment. <b>Conclusions:</b> B-ALL with MEF2D gene rearrangement predominantly affects older children, typically presenting with fever accompanied by arthralgia. This subtype exhibits high CD38 expression and absence of cIgM expression, with a frequent incidence of CDKN2A or CDKN2B gene deletions. Although the initial treatment response was good, the risk of recurrence was high and the efficacy of salvage treatment was limited. For this high-risk sub-type, the use of next-generation sequencing for MRD monitoring could be explored to more accurately assess the risk of relapse.</p>","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"941-946"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Passing the torch for 60 years, guarding children's gastrointestinal health with benevolence].","authors":"X Jiang, L Y Ye, Z H Huang, C D Xu, B X Wang, X W Xu, J Chen, H F Liu, M Z Jiang, Z L Li, Y Huang, X M Zhong, L L Geng, S N Shu, S T Gong, J Wu","doi":"10.3760/cma.j.cn112140-20260507-00367","DOIUrl":"10.3760/cma.j.cn112140-20260507-00367","url":null,"abstract":"","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 7","pages":"839-841"},"PeriodicalIF":0.0,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148260614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evaluation of quality-control management for pediatric fulminant myocarditis].","authors":"L J Yang, W T Zhao, Y C Zhang, Y Q Cui, J Wang, L W Lyu, Y X Guo, W Wang, X M Mo, R Lin","doi":"10.3760/cma.j.cn112140-20251230-01162","DOIUrl":"10.3760/cma.j.cn112140-20251230-01162","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To explore the efficacy of the implementation of quality control (QC) program for children with fulminant myocarditis (FM) on improving the survival rate, reducing mortality and complication rates, and to evaluate the feasibility of the QC protocol. &lt;b&gt;Methods:&lt;/b&gt; A retrospective cohort study was conducted. A Clinical Medical Quality Control Scoring Scale for Pediatric Fulminant Myocarditis (the QC Scale) was implemented since January 2021. Clinical data and the QC Scale data of 187 children with FM admitted to 8 tertiary hospitals capable of pediatric extracorporeal membrane oxygenation (ECMO) treatment over 6 years were collected, including the pre-QC group (January 2018 to December 2020) and the post-QC group (January 2021 to December 2023). Independent-samples &lt;i&gt;t&lt;/i&gt;-test, Mann-Whitney &lt;i&gt;U&lt;/i&gt; test, Chi-square test or Fisher's exact test were used for intergroup comparisons; and multivariate Logistic regression was performed for risk factor analysis. The clinical characteristics of pediatric FM and the feasibility and clinical efficacy of the QC protocol were evaluated. &lt;b&gt;Results:&lt;/b&gt; A total of 187 children with FM were enrolled, including 82 cases in the pre-QC period and 105 cases in the post-QC period. The age was (8±4) years, and the weight was (28±14) kg. There were 104 female cases (55.5%) and 83 male cases (44.5%). A total of 156 children survived and 31 died, with an overall in-hospital mortality rate of 16.6% (31/187). The completion rates of electrocardiogram or cardiac monitoring and echocardiography or non-invasive hemodynamic monitoring within 30 min after admission were 98.7% (81/82) and 92.6% (72/82) in the pre-QC group, compared with 96.2% (101/105) and 90.5% (95/105) in the post-QC group. The post-QC group showed significantly higher completion rates of blood lactate measurement and Glasgow Coma Scale assessment within 60 min of admission than the pre-QC group (86.5% (71/82) &lt;i&gt;vs.&lt;/i&gt; 98.1% (103/105), 62.2% (51/82) &lt;i&gt;vs.&lt;/i&gt; 81.9% (86/105), &lt;i&gt;χ²&lt;/i&gt;=9.43, 8.72; &lt;i&gt;P&lt;/i&gt;=0.002, 0.003). The pre-QC completion rates of reaching blood lactate ≤5 mmol/L, central venous oxygen saturation ≥65%, and urine output≥1 ml/(kg·h) at 12 h after treatment were 82.1%(46/56), 72.1%(31/43) and 72.7%(48/66), respectively, compared with 81.1%(77/95), 69.1%(47/68) and 80.9%(76/94) in the post-QC group. The time from admission to ECMO initiation was shorter in the post-QC group than in the pre-QC group ((11±17) &lt;i&gt;vs.&lt;/i&gt; (7±10) h, &lt;i&gt;t&lt;/i&gt;=2.09, &lt;i&gt;P&lt;/i&gt;=0.037). The mortality rates were 22.0% (18/82) in the pre-QC group and 12.4% (13/105) in the post-QC group. Compared with the pre-QC group, the post-QC group presented decreased rates of pre-ECMO cardiopulmonary resuscitation, cerebral injury and severe renal injury (51.2% (42/82) &lt;i&gt;vs.&lt;/i&gt; 28.6% (30/105), 19.5% (16/82) &lt;i&gt;vs.&lt;/i&gt; 8.6% (9/105), 19.5% (16/82) &lt;i&gt;vs.&lt;/i&gt; 8.6% (9/105); &lt;i&gt;χ²&lt;/i&gt;=9.97, 4.76, 4.76, all &lt;i&gt;P&lt;/i&gt;&lt;0.05). &lt;b&gt;Conclusions:&lt;/b&gt; The implementat","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 7","pages":"795-801"},"PeriodicalIF":0.0,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148260623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Expert consensus on the identification and management pathways of common emotional and psychosomatic problems in pediatric clinical services (2026)].","authors":"","doi":"10.3760/cma.j.cn112140-20260401-00260","DOIUrl":"10.3760/cma.j.cn112140-20260401-00260","url":null,"abstract":"","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 7","pages":"739-746"},"PeriodicalIF":0.0,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148260653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}