中华儿科杂志最新文献

{"title":"[Expert consensus on the clinical application and management of pediatric fecal microbiota transplantation (2026)].","authors":"","doi":"10.3760/cma.j.cn112140-20260120-00064","DOIUrl":"10.3760/cma.j.cn112140-20260120-00064","url":null,"abstract":"","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"863-872"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Post-tracheostomy complications and management advances in children requiring long-term mechanical ventilation].","authors":"J Y Sun, S Y Qian, C N Fan","doi":"10.3760/cma.j.cn112140-20260410-00291","DOIUrl":"10.3760/cma.j.cn112140-20260410-00291","url":null,"abstract":"","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"961-964"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical characteristics of periorbital and orbital cellulitis in children].","authors":"Y Chang, T M Chen, B Hu, L Y Guo, H L Hu, X Guo, L Zhu, Z Z Dou, W Y Feng, L L Liu, B Liu, H J Xiao, X Ning, Q J Li, Y Xie, W T Ge, S C Wang, X J Yang, J Wu, Q He, R H Wu, J Yin, H M Yang, L Li, Y W Fan, G Liu","doi":"10.3760/cma.j.cn112140-20260209-00129","DOIUrl":"10.3760/cma.j.cn112140-20260209-00129","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the clinical characteristics, causative pathogens, complications, and treatment outcomes of orbital cellulitis in children. <b>Methods:</b> A retrospective cohort study was performed. Clinical data including clinical characteristics, laboratory tests, pathogen profiles, and treatment were analyzed for 175 pediatric patients with orbital cellulitis admitted to Beijing Children's Hospital, Capital Medical University from January 2016 to December 2023. Patients were categorized by lesion location into periorbital cellulitis (PC) and orbital cellulitis (OC) groups; by complication status into with and without complications. Intergroup comparisons were performed using the chi-square test and Mann-Whitney <i>U</i> test. Logistic regression analysis was used to identify risk factors for complications. <b>Results:</b> Of the 175 patients, 116 were male and 59 were female, with an age at presentation of 3.6 (2.1, 6.7) years. There were 81 patients in the PC group and 94 in the OC group. All patients presented with eyelid and periorbital erythema and edema. The OC group demonstrated higher proportions of males, sinusitis, proptosis, ocular motility disorders, bulbar conjunctival edema, and decreased visual acuity compared to the PC group, C-reactive protein levels, neutrophil counts, and platelet counts in the acute phase were also significantly higher in the OC group (all <i>P</i><0.05). A definitive microbiological diagnosis was established in 74 cases (42.3%), and a total of 76 pathogenic strains were isolated. The most common pathogen was <i>Staphylococcus aureus</i>, accounting for 47 strains (61.8%), including 33 strains (43.4%) of methicillin-susceptible <i>Staphylococcus aureus</i>, and 14 strains (18.4%) of methicillin-resistant <i>Staphylococcus aureus</i>, followed by <i>Streptococcus intermedius</i> and <i>Streptococcus</i> constellatus with 6 strains each (7.9%), and <i>Streptococcus</i> pneumoniae and <i>Pseudomonas aeruginosa</i> with 4 strainss each (5.3%). Complications developed in 47 cases (26.8%), most commonly orbital abscesses in 29 cases (16.6%), followed by purulent meningitis in 14 cases (8.0%). Multivariate logistic regression analysis identified proptosis (<i>OR</i>=3.56, 95%<i>CI</i> 1.49-8.49), decreased visual acuity (<i>OR</i>=4.45, 95%<i>CI</i> 1.27-15.66), and headache (<i>OR</i>=2.76, 95%<i>CI</i> 1.01-7.57) as independent risk factors for complications (all <i>P</i><0.05). <b>Conclusions:</b> Orbital cellulitis in children commonly presents with eyelid and periorbital redness and swelling. Male sex, sinusitis, proptosis, ocular motility disorders, bulbar conjunctival edema, and decreased vision acuity serve as high-risk indicators for orbital cellulitis. Elevated C-reactive protein, neutrophil count, and platelet counts in the acute phase are laboratory makers closely associated with orbital cellulitis. <i>Staphylococcus aureus</i> is the most common causative pathogen. Decreased vision ","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"881-886"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Advances in terminology related to childhood interstitial lung disease].","authors":"J H Chen, Y J Zheng","doi":"10.3760/cma.j.cn112140-20260109-00022","DOIUrl":"10.3760/cma.j.cn112140-20260109-00022","url":null,"abstract":"","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"958-961"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Obesity characteristics and body composition in children with osteogenesis imperfecta].","authors":"X Q Xu, J P Zheng, X L Zhou, H Lin, X F Chen, T Yuan, K Huang, G P Dong, J S Chen, J F Fu, W Wu","doi":"10.3760/cma.j.cn112140-20260205-00118","DOIUrl":"10.3760/cma.j.cn112140-20260205-00118","url":null,"abstract":"<p><p><b>Objective:</b> To describe the clinical symptoms, obesity status and body composition distribution in children with osteogenesis imperfecta (OI). <b>Methods:</b> This retrospective cohort study included 45 children aged 0-18 years with OI, diagnosed by clinical and genetic testing at Children's Hospital, Zhejiang University School of Medicine, from October 2020 to February 2025. Clinical data were collected on age, sex, symptoms, imaging examinations and genetic testing results. According to body mass index (BMI) criteria or weight-for-length Z-score, the OI patients were divided into non-overweight or obese group and overweight or obese group. Concurrently, 60 children with simple overweight or obesity, matched for sex, age and BMI, were enrolled as a control group. The <i>t</i>-test and Mann-Whitney <i>U</i> test were used to compare the clinical characteristics between the 2 OI groups, and body composition (lean mass index (LMI)and fat mass index (FMI)) between the overweight or obese OI group and the control group. Fracture frequency distribution between the two OI groups were compared using the <i>χ</i>² test. <b>Results:</b> Of the 45 OI children, 26 were male and 19 female, with an average age of (7.2±3.9) years. Genetic variants involved COL1A1 or COL1A2 in 40 cases, IFITM5 in 3, SERPINF1 in 1, and BMP1 in 1. Of the OI patients, 18 (40%) were in the overweight or obesity group and 27 (60%) in the non-overweight or obesity group; 19 (42%) had short stature or growth retardation. Between the 2 OI groups, none of sex, osteocalcin, bone mineral density Z-score, or vitamin D level differed significantly (all <i>P</i>>0.05), whereas fracture frequency did differ significantly (<i>P</i><0.05). Twenty seven OI children (13 in the overweight or obesity group and 14 in the non-overweight or obesity group) completed the dual-energy X-ray absorptiometry, and all of them had COL1A1 or COL1A2 genotypes. The FMI level was higher in the overweight or obese group than in the non-overweight or obese group (9.0 (6.1, 9.6) <i>vs.</i> 4.4 (3.7, 5.6) kg/m², <i>Z</i>=3.21, <i>P</i>=0.005), whereas LMI and abdominal-to-gluteal fat percentage ratio did not differ significantly (both <i>P</i>>0.05). In the OI overweight or obesity group, both FMI and LMI were lower than in the control group (9.0 (6.1, 9.6) <i>vs.</i> 10.4 (9.2, 11.7) kg/m², 12.1 (11.7, 12.9) <i>vs.</i> 13.9 (13.0, 15.1) kg/m², <i>Z</i>=3.45,3.72, both <i>P</i><0.05). <b>Conclusions:</b> Overweight or obesity was prevalent among children with OI and was closely associated with fracture frequency. Among those with COL1A1 or COL1A2 variants, the overweight or obese OI children was characterized by higher FMI and lower LMI.</p>","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"930-935"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical features and antimicrobial resistance analysis of invasive non-typhoid <i>Salmonella</i> infection in children at Xi'an].","authors":"J F Shi, J Y Tang, R N Li, C Shu, X J Yang, B L Lu","doi":"10.3760/cma.j.cn112140-20260316-00212","DOIUrl":"10.3760/cma.j.cn112140-20260316-00212","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To investigate the clinical characteristics, serogroups and antimicrobial resistance of invasive non-typhoid &lt;i&gt;Salmonella&lt;/i&gt; infection in children at Xi'an area. &lt;b&gt;Methods:&lt;/b&gt; Retrospective cohort study. The clinical manifestations, treatment, prognosis, serogroups and antimicrobial drug resistance of 51 hospitalized children with invasive non-typhoid &lt;i&gt;Salmonella&lt;/i&gt; infection confirmed by sterile body fluids or deep pus culture after operation at the Department of Infectious Diseases, the Department of General Surgery and the Department of Orthopedics in Xi'an Children's Hospital from January 2019 to December 2024 were retrospectively analyzed. The patients were divided into bloodstream infection group and local infection group according to the invasion site. The inflammatory markers, serogroups distribution and antimicrobial resistance were analyzed statistically by using Mann-Whitney &lt;i&gt;U&lt;/i&gt; test and &lt;i&gt;χ&lt;/i&gt;&lt;sup&gt;2&lt;/sup&gt; test. &lt;b&gt;Results:&lt;/b&gt; Among the 51 children, there were 27 males and 24 females, with an onset age of 19 (14, 40) months. Nine cases (17%) were &lt;1 year old, 28 cases (55%) under 1 - &lt;3 years old, 7 cases (14%) under 3-&lt;6 years old and 7 cases (14%) ≥ 6 years old. The onset time of 44 cases (86%) was from April to October. The diseases included 41 cases of bloodstream infection group, 10 cases of local infection group(including 6 cases of osteomyelitis involving the hip joint or humerus or pubis or navicular bone, 2 case of appendicitis with peritonitis and 2 cases of perianal or intra-abdominal abscess). The clinical manifestations were fever in 45 cases(88%), diarrhea and abdominal pain in 22 cases (43%), nausea and vomiting in 11 cases (22%), mesenteric lymphadenopathy in 4 cases (8%). Thirty-one cases (61%) were cured and twenty cases (39%) were improved by effective antibiotics treatment. White blood cell count in local infection group was significantly higher than that in bloodstream infection group (&lt;i&gt;P&lt;/i&gt;&lt;0.05).The serogroups of D (&lt;i&gt;Salmonella&lt;/i&gt; enteritidis), C and B were the most prevalent among non-typhoid Salmonella isolates, accounting for 21 cases (41%), 10 cases (20%) and 10 cases (20%) respectively. Antibacterial drug sensitivity test showed that the sensitivity rates of piperaciratazobactam, ertapenem and imipenem all were 100% (51/51), those of ceftazidime, ceftriaxone and cefepime were 80% (41/51), 80% (41/51) and 86% (44/51), respectively. The drug resistance(including intermediate) rates of trimethoprim-sulfamethoxazole, aztreonam, ampicillin, ampicillin-sulbactam and ciprofloxacin were 24% (12/51), 16% (8/51), 57% (29/51), 57% (29/51) and 75% (38/51), respectively. There were no statistical differences in the drug resistance (including intermediate) rates of ceftazidime, ceftriaxone, cefepime, trimethoprim-sulfamethoxazole, ampicillin, ampicillin-sulbactam, aztreonam and ciprofloxacin between the bloodstream infection group and local infection group (all &lt;i&gt;P&lt;/i&gt;&gt;0.05). ","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"893-897"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Age-stratified analysis of left ventricular ejection fraction threshold heterogeneity for heart failure with preserved ejection fraction in children].","authors":"S Y Huang, J Gao, Y X Yuan, H X Huang, F J Wang, Z Chen, Y Guo, X Shen, X C Liang, B Pan, T W Lyu, J Tian","doi":"10.3760/cma.j.cn112140-20251214-01102","DOIUrl":"10.3760/cma.j.cn112140-20251214-01102","url":null,"abstract":"<p><p><b>Objective:</b> To explore age-adapted left ventricular ejection fraction (LVEF) diagnostic thresholds for heart failure with preserved ejection fraction (HFpEF) in children. <b>Methods:</b> In this multicenter retrospective cohort study, children with chronic heart failure were selected from 3 546 hospitalized pediatric heart failure patients across 30 medical centers in 20 provinces, autonomous regions and municipalities in China from January 2013 to December 2022. Children were divided into 3 groups based on LVEF:<50%, 50%-<55%, and ≥55%. Age-stratified analyses were performed using cutoffs at 9, 10, 11, 12, and 13 years of age. Intergroup comparisons were conducted using the chi-square test or Fisher's exact test, Wilcoxon rank-sum test or Kruskal-Wallis test. Multivariable linear regression was used to analyze the independent association between LVEF categories and cardiac structural parameters. <b>Results:</b> A total of 1 018 pediatric patients were included in the analysis. Among them, 527 (51.8%) were male and 491 (48.2%) were female, with an age of 1.2 (0.4, 7.1) years. There were 447 children in LVEF <50% group, 62 children in 50%-<55% group, and 509 children in ≥55% group. Statistical differences in baseline clinical characteristics were observed among the 3 groups, including age, heart rate, respiratory symptoms, systemic congestion symptoms, congenital heart disease, cardiomyopathy cardiovascular events, growth retardation (all <i>P</i><0.05). Age-stratified analysis showed that when using 9, 10 and 11 years of age as cutoffs, left ventricular end-systolic diameter (LVESD) differed between the LVEF <50% and 50%-<55% groups in children aged at or above the respective cutoff (all <i>P</i><0.05). When using 12 and 13 years of age as the cutoff, left atrial diameter differed between the LVEF 50%-<55% and ≥55% groups in children below 12 and 13 years of age (both <i>P</i><0.05). After adjustment for covariates using multivariable linear regression, when using 10 and 11 years of age as the cut-offs, LVEF were correlated with LVESD in both children aged ≥10 years and those aged ≥11 years (<i>β</i>=11.62 and 10.94,95%<i>CI</i> 2.38-20.85 and 1.32-20.56, <i>P</i>=0.018 and 0.029). And when using 12 years of age as the cut-offs, LVEF was correlated with left atrial diameter in children aged <12 years of age (<i>β</i>=-1.82,95%<i>CI</i> -3.29--0.35,<i>P</i>=0.015). <b>Conclusion:</b> Age-related heterogeneity may exist in the LVEF thresholds for pediatric HFpEF, an LVEF threshold of 55% is recommended for children younger than 12 years, whereas 50% consistent with adult criteria, may be considered for those aged 12 years or older.</p>","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"898-904"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Guideline for diagnosis, treatment and prevention of type 1 diabetes mellitus in children(2026)].","authors":"","doi":"10.3760/cma.j.cn112140-20260309-00194","DOIUrl":"10.3760/cma.j.cn112140-20260309-00194","url":null,"abstract":"","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"853-862"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Advances in the molecular mechanisms and targeted therapy of acute megakaryoblastic leukemia].","authors":"S W Hu, X W Zhai","doi":"10.3760/cma.j.cn112140-20251215-01110","DOIUrl":"10.3760/cma.j.cn112140-20251215-01110","url":null,"abstract":"","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"954-957"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Construction of a risk prediction model for vascular function damage in children with primary hypertension].","authors":"Y Liu, Y Lin, Y Y Liu, M Bao, Y Q Li, C Wu, H Jiang, L Shi","doi":"10.3760/cma.j.cn112140-20251119-01039","DOIUrl":"10.3760/cma.j.cn112140-20251119-01039","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the risk factors of vascular function damage in children with primary hypertension and establish a risk prediction model. <b>Methods:</b> In this retrospective case-control study, a total of 117 children aged 6-17 years with primary hypertension, hospitalized at Capital Center for Children's Health, Capital Medical University, between February 2024 and October 2025 were included. Flow mediated dilation (FMD) and carotid-femoral pulse wave velocity (cfPWV) were used as indicators of vascular function impairment. The children were divided into a vascular function damage group and a normal vascular function group according to the presence or absence of vascular function damage. Independent samples <i>t</i>-test or Mann-Whitney <i>U</i> test was used for intergroup comparison of measurement data, <i>χ</i>² test or Fisher's exact test was used for enumeration data. Differences in clinical, laboratory and vascular function-related indicators were compared between the two groups. Multivariate Logistic regression was employed to identify independent risk factors, based on which a nomogram was constructed. The predictive performance was verified by the receiver operating characteristic (ROC) curve. <b>Results:</b> Among 117 hypertensive children, there were 92 (78.6%) males and 25 (21.4%) females, with the age of (13.0±2.1) years at admission. There was 58 (49.6%) with vascular function damage. The body fat percentage, 24 h mean systolic blood pressure, daytime systolic blood pressure, nocturnal systolic blood pressure, low-density lipoprotein, total cholesterol, triglycerides, homocysteine, folic acid, fasting insulin, uric acid and cfPWV levels in the vascular function damage group (58 cases) were significantly higher than those in the normal group (59 cases), while the FMD level in the vascular function damage group was significantly lower than that in the normal group (all <i>P</i><0.05). Multivariate Logistic regression identified that: nocturnal systolic blood pressure (SBP) (<i>OR</i>=1.06, 95%<i>CI</i> 1.01-1.10, <i>P</i>=0.019), serum low-density lipoprotein (LDL) (<i>OR</i>=5.51,95%<i>CI</i> 2.41-12.58,<i>P</i><0.001), and homocysteine (<i>OR</i>=1.11,95%<i>CI</i> 1.03-1.19,<i>P</i>=0.005) were independent risk factors for vascular function damage. A nomogram prediction model was constructed accordingly, and the Logistic regression equation was: Logit(<i>P</i>)=-10.73+0.05×nocturnal systolic blood pressure+1.71×low-density lipoprotein+0.10×homocysteine. The ROC curve for the nomogram showed an area under curve of 0.82 (95%<i>CI</i> 0.74-0.89, <i>P<</i>0.001), with a sensitivity of 0.76 and a specificity of 0.71. <b>Conclusion:</b> Nocturnal systolic blood pressure, low-density lipoprotein and homocysteine are independent risk factors for vascular function damage in children with primary hypertension.</p>","PeriodicalId":60813,"journal":{"name":"中华儿科杂志","volume":"64 8","pages":"905-910"},"PeriodicalIF":0.0,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}