Epilepsy and Behavior Case Reports最新文献

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Anterior corpus callosotomy in patients with drug-resistant epilepsy: Invasive EEG findings and seizure outcomes 前胼胝体切开术治疗耐药癫痫患者:侵入性脑电图结果和癫痫发作结果
Epilepsy and Behavior Case Reports Pub Date : 2018-01-01 DOI: 10.1016/j.ebcr.2017.12.001
Olga Taraschenko , Swetha Pedavally , Kaeli K. Samson , Mark J. Puccioni , Deepak Madhavan
{"title":"Anterior corpus callosotomy in patients with drug-resistant epilepsy: Invasive EEG findings and seizure outcomes","authors":"Olga Taraschenko ,&nbsp;Swetha Pedavally ,&nbsp;Kaeli K. Samson ,&nbsp;Mark J. Puccioni ,&nbsp;Deepak Madhavan","doi":"10.1016/j.ebcr.2017.12.001","DOIUrl":"10.1016/j.ebcr.2017.12.001","url":null,"abstract":"<div><p>Corpus callosotomy (CC) is used in patients with drug-resistant seizures who are not candidates for excisional surgery and failed neurostimulation. We examined ictal scalp and intracranial electroencephalogram (iEEG) recordings in 16 patients being evaluated for anterior CC alone or CC in combination with focal resection, to determine the role of the iEEG in predicting postoperative seizure outcomes. In our cohort, CC improved generalized atonic seizures and focal seizures with impaired awareness but did not alter outcomes for generalized tonic–clonic or tonic seizures. Invasive EEG prior to CC did not refine the prediction of postsurgical seizure outcomes in patients with inconclusive scalp EEG.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"9 ","pages":"Pages 12-18"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2017.12.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36040939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Repetitive transcranial magnetic stimulation directed to a seizure focus localized by high-density EEG: A case report 重复经颅磁刺激定向癫痫病灶定位高密度脑电图:1例报告
Epilepsy and Behavior Case Reports Pub Date : 2018-01-01 DOI: 10.1016/j.ebcr.2018.03.004
Robert Fisher, Jing Zhou, Adam Fogarty, Aditya Joshi, Matthew Markert, Gayle K. Deutsch, Mariel Velez
{"title":"Repetitive transcranial magnetic stimulation directed to a seizure focus localized by high-density EEG: A case report","authors":"Robert Fisher,&nbsp;Jing Zhou,&nbsp;Adam Fogarty,&nbsp;Aditya Joshi,&nbsp;Matthew Markert,&nbsp;Gayle K. Deutsch,&nbsp;Mariel Velez","doi":"10.1016/j.ebcr.2018.03.004","DOIUrl":"10.1016/j.ebcr.2018.03.004","url":null,"abstract":"<div><p>We demonstrate feasibility of using high-density EEG to map a neocortical seizure focus in conjunction with delivery of magnetic therapy. Our patient had refractory seizures affecting the left leg. A five-day course of placebo stimulation followed a month later by active rTMS was directed to the mapped seizure dipole. Active rTMS resulted in reduced EEG spiking, and shortening of seizure duration compared to placebo. Seizure frequency, however, improved similarly in both placebo and active treatment stages. rTMS-evoked EEG potentials demonstrated that a negative peak at 40 ms - believed to represent GABAergic inhibition - was enhanced by stimulation.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"10 ","pages":"Pages 47-53"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2018.03.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36294463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Extra operative intracranial EEG monitoring for epilepsy surgery in elderly patients 老年癫痫手术患者术外颅内脑电图监测
Epilepsy and Behavior Case Reports Pub Date : 2018-01-01 DOI: 10.1016/j.ebcr.2018.07.002
Vineet Punia , Juan Bulacio , Jorge Gonzalez-Martinez , Ahmed Abdelkader , William Bingaman , Imad Najm , Andrey Stojic
{"title":"Extra operative intracranial EEG monitoring for epilepsy surgery in elderly patients","authors":"Vineet Punia ,&nbsp;Juan Bulacio ,&nbsp;Jorge Gonzalez-Martinez ,&nbsp;Ahmed Abdelkader ,&nbsp;William Bingaman ,&nbsp;Imad Najm ,&nbsp;Andrey Stojic","doi":"10.1016/j.ebcr.2018.07.002","DOIUrl":"10.1016/j.ebcr.2018.07.002","url":null,"abstract":"<div><h3>Object</h3><p>The objective of the study is to investigate and report our experience with extra operative intracranial EEG monitoring for evaluation of epilepsy surgery among elderly (≥<!--> <!-->60 years) patients.</p></div><div><h3>Methods</h3><p>After IRB approval, we searched our prospectively maintained epilepsy surgery database to find patients who underwent eiEEG at the age of 60 years or older. Electronic medical records were reviewed to extract clinical and surgery-related information. Patients who underwent resective epilepsy surgery after eiEEG and had at least 1 year of clinical follow-up were assessed for seizure outcome. Categorical and continuous variables were compared using Pearson chi-square and Student's t-test, respectively.</p></div><div><h3>Results</h3><p>A total of 21 patients, with 13 (62%) women, underwent eiEEG in our center at the age of 60 years or older. The mean age at time of implantation was 63.8 ± 2.7 years. Sub-dural grids (SDG) were implanted in five (24%) patients, whereas sixteen (76%) patients underwent stereo-EEG (SEEG) implantation. Median number of contacts in SDG were 106 (56–136) and depth electrodes in SEEG were 12 (9–14). There were 2 complications, including one mortality due to intracerebral hemorrhage. Sixteen (76%) patients underwent respective epilepsy surgery after eiEEG and eleven (69%) achieved Engel class I outcome on the last follow-up [mean follow-up duration of 2.7 (± 1.8) years].</p></div><div><h3>Conclusion</h3><p>We noticed an increased utilization of eiEEG in elderly patients after the introduction of SEEG at our center. Overall, we found that eiEEG can help achieve good seizure outcomes in the elderly population. However, the one eiEEG-related mortality serves a word of caution about the potential risks in this population.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"10 ","pages":"Pages 92-95"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2018.07.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36399554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Autoimmune encephalitis associated with two antibodies 自身免疫性脑炎与两种抗体相关
Epilepsy and Behavior Case Reports Pub Date : 2018-01-01 DOI: 10.1016/j.ebcr.2018.04.001
Nikolai Gil D. Reyes, Mario B. Prado, Christian Wilson R. Turalde, Marc Laurence L. Fernandez
{"title":"Autoimmune encephalitis associated with two antibodies","authors":"Nikolai Gil D. Reyes,&nbsp;Mario B. Prado,&nbsp;Christian Wilson R. Turalde,&nbsp;Marc Laurence L. Fernandez","doi":"10.1016/j.ebcr.2018.04.001","DOIUrl":"10.1016/j.ebcr.2018.04.001","url":null,"abstract":"","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"10 ","pages":"Pages 44-46"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2018.04.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36245470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Seizures in HIV: The case for special consideration 艾滋病毒癫痫:需要特别考虑的案例
Epilepsy and Behavior Case Reports Pub Date : 2018-01-01 DOI: 10.1016/j.ebcr.2018.02.006
Lilia Zaporojan , Patricia H. McNamara , Jennifer A. Williams , Colm Bergin , Janice Redmond , Colin P. Doherty
{"title":"Seizures in HIV: The case for special consideration","authors":"Lilia Zaporojan ,&nbsp;Patricia H. McNamara ,&nbsp;Jennifer A. Williams ,&nbsp;Colm Bergin ,&nbsp;Janice Redmond ,&nbsp;Colin P. Doherty","doi":"10.1016/j.ebcr.2018.02.006","DOIUrl":"10.1016/j.ebcr.2018.02.006","url":null,"abstract":"<div><h3>Purpose</h3><p>This study aimed to determine the rate, cause and management of seizures in the context of potential ART–ASD interactions in a cohort of HIV<!--> <!-->+ individuals.</p></div><div><h3>Methods</h3><p>Records of 604 HIV<!--> <!-->+ patients were reviewed and those reporting epilepsy/seizure diagnosis were further evaluated.</p></div><div><h3>Results</h3><p>This cohort exhibited a seizure rate of 2.4%. HIV<!--> <!-->+ patients treated for epilepsy displayed low serum ASD levels and failed to achieve seizure control. They were more likely to disengage from Neurology follow-up.</p></div><div><h3>Conclusion</h3><p>For HIV<!--> <!-->+ patients presenting with seizures/epilepsy the ASD prescription and the provision of supplementary support services needs to be carefully considered.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"10 ","pages":"Pages 38-43"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2018.02.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36317164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
An interaction between warfarin and cannabidiol, a case report 华法林与大麻二酚的相互作用,一例报告
Epilepsy and Behavior Case Reports Pub Date : 2018-01-01 DOI: 10.1016/j.ebcr.2017.10.001
Leslie Grayson , Brannon Vines , Kate Nichol , Jerzy P. Szaflarski , for the UAB CBD Program
{"title":"An interaction between warfarin and cannabidiol, a case report","authors":"Leslie Grayson ,&nbsp;Brannon Vines ,&nbsp;Kate Nichol ,&nbsp;Jerzy P. Szaflarski ,&nbsp;for the UAB CBD Program","doi":"10.1016/j.ebcr.2017.10.001","DOIUrl":"10.1016/j.ebcr.2017.10.001","url":null,"abstract":"","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"9 ","pages":"Pages 10-11"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2017.10.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35782331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 80
Seizure frequency can be reduced by changing intracranial pressure: A case report in drug-resistant epilepsy 改变颅内压可降低癫痫发作频率:耐药性癫痫1例报告
Epilepsy and Behavior Case Reports Pub Date : 2018-01-01 DOI: 10.1016/j.ebcr.2017.12.005
Daiki Uchida, Ayataka Fujimoto, Tomohiro Yamazoe, Takamichi Yamamoto, Hideo Enoki
{"title":"Seizure frequency can be reduced by changing intracranial pressure: A case report in drug-resistant epilepsy","authors":"Daiki Uchida,&nbsp;Ayataka Fujimoto,&nbsp;Tomohiro Yamazoe,&nbsp;Takamichi Yamamoto,&nbsp;Hideo Enoki","doi":"10.1016/j.ebcr.2017.12.005","DOIUrl":"10.1016/j.ebcr.2017.12.005","url":null,"abstract":"<div><p>A relationship between seizures and intracranial pressure (ICP) has been proposed, but not clearly identified. Whether changes in ICP can evoke seizures remains controversial. We report the case of a 23-year-old man who had undergone shunt surgery in childhood and later presented with focal impaired awareness seizures and behavior arrest. Seizures were uncontrolled despite 3<!--> <!-->years of pharmacotherapy, but suddenly stopped after shunt removal. Our case supports the hypothesis that drug-resistant epilepsy can be influenced by changes in ICP. In particular, this case indicates that elevations in ICP may help reduce some seizures.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"10 ","pages":"Pages 14-17"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2017.12.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36359149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Lacosamide may improve cognition in patients with focal epilepsy: EpiTrack to compare cognitive side effects of lacosamide and carbamazepine 拉科沙胺可能改善局灶性癫痫患者的认知:比较拉科沙胺和卡马西平的认知副作用
Epilepsy and Behavior Case Reports Pub Date : 2018-01-01 DOI: 10.1016/j.ebcr.2018.02.004
Claudio Liguori , Francesca Izzi , Natalia Manfredi , Nicola Biagio Mercuri , Fabio Placidi
{"title":"Lacosamide may improve cognition in patients with focal epilepsy: EpiTrack to compare cognitive side effects of lacosamide and carbamazepine","authors":"Claudio Liguori ,&nbsp;Francesca Izzi ,&nbsp;Natalia Manfredi ,&nbsp;Nicola Biagio Mercuri ,&nbsp;Fabio Placidi","doi":"10.1016/j.ebcr.2018.02.004","DOIUrl":"10.1016/j.ebcr.2018.02.004","url":null,"abstract":"<div><p>Carbamazepine (CBZ) is a first generation anti-seizure drug, considered as first choice therapy in focal epilepsy but associated with cognitive side effects. Lacosamide (LCM) is a third-generation anti-seizure drug approved for treating focal epilepsy. This case series documented the comparable efficacy of LCM and CBZ as first add on treatments in patients affected by uncontrolled focal seizures. LCM showed an increase in EpiTrack scores, which measure cognitive abilities, at follow-up compared to CBZ. This preliminary data may represent the basis for future prospective studies aimed at comparing the long-term cognitive side effects of LCM and CBZ.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"10 ","pages":"Pages 35-37"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2018.02.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36288344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Intracarotid amobarbital disrupts synchronous and nested oscillatory activity ipsilateral to injection 颈动脉内阿巴比妥破坏同侧注射的同步和嵌套振荡活动
Epilepsy and Behavior Case Reports Pub Date : 2018-01-01 DOI: 10.1016/j.ebcr.2018.04.003
James J. Young , Joshua S. Friedman , Thomas J. Oxley , Christina Palmese , Fedor Panov , Saadi Ghatan , Johanna T. Fifi , Lara V. Marcuse
{"title":"Intracarotid amobarbital disrupts synchronous and nested oscillatory activity ipsilateral to injection","authors":"James J. Young ,&nbsp;Joshua S. Friedman ,&nbsp;Thomas J. Oxley ,&nbsp;Christina Palmese ,&nbsp;Fedor Panov ,&nbsp;Saadi Ghatan ,&nbsp;Johanna T. Fifi ,&nbsp;Lara V. Marcuse","doi":"10.1016/j.ebcr.2018.04.003","DOIUrl":"10.1016/j.ebcr.2018.04.003","url":null,"abstract":"<div><p>The mechanism of amobarbital action during the intracarotid amobarbital procedure is poorly understood. We report a patient case who underwent IAP while implanted with bilateral stereo-EEG. We analyzed the spectral power, phase amplitude coupling, and cluster-phase group synchrony during the procedure. Delta and gamma power increased bilaterally. By contrast, phase amplitude coupling increased only ipsilateral to the injection. Similarly, 4–30 Hz cluster-phase group synchrony declines and gamma cluster-phase group synchrony increases only ipsilateral to the injection. These results suggest that a possible additional mechanism for amobarbital action in the IAP is by altering the precise timing of oscillatory activity.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"10 ","pages":"Pages 25-28"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2018.04.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36317162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adjunctive perampanel for glioma-associated epilepsy 胶质瘤相关性癫痫的辅助治疗
Epilepsy and Behavior Case Reports Pub Date : 2018-01-01 DOI: 10.1016/j.ebcr.2018.09.003
Anastasie M. Dunn-Pirio , Sarah Woodring , Eric Lipp , James E. Herndon II , Patrick Healy , Mallika Weant , Dina Randazzo , Annick Desjardins , Henry S. Friedman , Katherine B. Peters
{"title":"Adjunctive perampanel for glioma-associated epilepsy","authors":"Anastasie M. Dunn-Pirio ,&nbsp;Sarah Woodring ,&nbsp;Eric Lipp ,&nbsp;James E. Herndon II ,&nbsp;Patrick Healy ,&nbsp;Mallika Weant ,&nbsp;Dina Randazzo ,&nbsp;Annick Desjardins ,&nbsp;Henry S. Friedman ,&nbsp;Katherine B. Peters","doi":"10.1016/j.ebcr.2018.09.003","DOIUrl":"10.1016/j.ebcr.2018.09.003","url":null,"abstract":"<div><p>Glioma-associated epilepsy is associated with excessive glutamate signaling. We hypothesized that perampanel, an amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptor antagonist, would treat glioma-related epilepsy. We conducted a single-arm study of adjunctive perampanel for patients with focal-onset glioma-associated seizures. The most common related adverse events were fatigue and dizziness. Three out of 8 participants had self-reported seizure reduction and an additional 3 reported improved control. Of these 6, 5 had isocitrate dehydrogenase 1 mutant gliomas. We conclude that perampanel is safe for patients with glioma-related focal-onset epilepsy. Further study into the association between AMPA signaling, IDH1 status and seizures is warranted.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"10 ","pages":"Pages 114-117"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2018.09.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36620930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
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