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Epilepsy and Behavior Case Reports最新文献

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Continuous ictal discharges with high frequency oscillations confined to the non-sclerotic hippocampus in an epileptic patient with radiation-induced cavernoma in the lateral temporal lobe 伴有辐射诱发的颞叶侧海绵状瘤的癫痫患者非硬化海马的持续高频振荡发作放电
Epilepsy and Behavior Case Reports Pub Date : 2019-01-01 DOI: 10.1016/j.ebcr.2019.01.003
Nobutaka Mukae , Takato Morioka , Michiko Torio , Ayumi Sakata , Satoshi O. Suzuki , Koji Iihara
{"title":"Continuous ictal discharges with high frequency oscillations confined to the non-sclerotic hippocampus in an epileptic patient with radiation-induced cavernoma in the lateral temporal lobe","authors":"Nobutaka Mukae ,&nbsp;Takato Morioka ,&nbsp;Michiko Torio ,&nbsp;Ayumi Sakata ,&nbsp;Satoshi O. Suzuki ,&nbsp;Koji Iihara","doi":"10.1016/j.ebcr.2019.01.003","DOIUrl":"10.1016/j.ebcr.2019.01.003","url":null,"abstract":"<div><p>Intraoperative electrocorticography recording is recommended for treating cavernoma-related epilepsy. However, interictal paroxysmal epileptiform activity is generally able to be recorded, but is not always identical to the epileptogenic zone.</p><p>We surgically treated a 15-year-old girl with drug-resistant epilepsy associated with radiation-induced cavernoma in the right lateral temporal lobe. Electrocorticography revealed paroxysmal activities in the cortex around the cavernoma. Additionally, continuous subclinical “ictal” discharges with high-frequency oscillations confined to the histologically non-sclerotic hippocampus were recorded. Following additional hippocampectomy, a good seizure outcome was obtained.</p><p>Intraoperative electrocorticography and high-frequency oscillation analysis revealed high epileptogenicity in the non-sclerotic hippocampus of this patient.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"11 ","pages":"Pages 87-91"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2019.01.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36988982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Long term seizure freedom on perampanel in highly drug-resistant epilepsy caused by bilateral periventricular nodular heterotopia: A case report perampanel治疗双侧脑室周围结节性异位致高度耐药癫痫1例
Epilepsy and Behavior Case Reports Pub Date : 2019-01-01 DOI: 10.1016/j.ebcr.2019.01.009
Makoto Kiyose , Marlies Wagner , Annika Männer , Sarah C. Reitz , Karl Martin Klein , Adam Strzelczyk , Sebastian Bauer , Felix Rosenow
{"title":"Long term seizure freedom on perampanel in highly drug-resistant epilepsy caused by bilateral periventricular nodular heterotopia: A case report","authors":"Makoto Kiyose ,&nbsp;Marlies Wagner ,&nbsp;Annika Männer ,&nbsp;Sarah C. Reitz ,&nbsp;Karl Martin Klein ,&nbsp;Adam Strzelczyk ,&nbsp;Sebastian Bauer ,&nbsp;Felix Rosenow","doi":"10.1016/j.ebcr.2019.01.009","DOIUrl":"10.1016/j.ebcr.2019.01.009","url":null,"abstract":"","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"11 ","pages":"Pages 99-102"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2019.01.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37234934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Are there mortality risks for patients with epilepsy who use cannabis treatments as monotherapy? 使用大麻作为单一疗法的癫痫患者是否存在死亡风险?
Epilepsy and Behavior Case Reports Pub Date : 2019-01-01 DOI: 10.1016/j.ebcr.2018.11.007
Devon M. Kollmyer , Kyla E. Wright , Nicole M. Warner , Michael J. Doherty
{"title":"Are there mortality risks for patients with epilepsy who use cannabis treatments as monotherapy?","authors":"Devon M. Kollmyer ,&nbsp;Kyla E. Wright ,&nbsp;Nicole M. Warner ,&nbsp;Michael J. Doherty","doi":"10.1016/j.ebcr.2018.11.007","DOIUrl":"10.1016/j.ebcr.2018.11.007","url":null,"abstract":"<div><p>Mortality associated with cannabis used for treatment of epilepsy is not well documented. We discuss two fatalities in the setting of epilepsy and self-determined therapy with cannabis (SDTC). One patient had probable sudden unexpected death in epilepsy, the second death was due to seizure-associated drowning. Both directed SDTC over conventional anti-seizure medications. Where recreational cannabis is legal, decisions to use cannabis are often self-directed and independent of physician advice of cannabis risks, in part because physicians may not be aware of the risk of SDTC. Further study of morbidity and mortality of SDTC in patients with epilepsy is needed.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"11 ","pages":"Pages 52-53"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2018.11.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36918845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Forced normalization after turning off vagus nerve stimulation in Lennox–Gastaut syndrome lenox - gastaut综合征中关闭迷走神经刺激后的强迫正常化
Epilepsy and Behavior Case Reports Pub Date : 2019-01-01 DOI: 10.1016/j.ebcr.2019.01.004
Sydney Lee , Alyssa Denton , Lady Diana Ladino , Karen Waterhouse , Aleksander Vitali , Jose Francisco Tellez-Zenteno
{"title":"Forced normalization after turning off vagus nerve stimulation in Lennox–Gastaut syndrome","authors":"Sydney Lee ,&nbsp;Alyssa Denton ,&nbsp;Lady Diana Ladino ,&nbsp;Karen Waterhouse ,&nbsp;Aleksander Vitali ,&nbsp;Jose Francisco Tellez-Zenteno","doi":"10.1016/j.ebcr.2019.01.004","DOIUrl":"10.1016/j.ebcr.2019.01.004","url":null,"abstract":"<div><p>Forced normalization is the development of psychiatric symptoms in a patient experiencing remission of seizures. We present a case of Lennox Gastaut syndrome in which forced normalization developed after vagus nerve stimulation was stopped.</p><p>The patient had drug resistant epilepsy and failed anti-seizure drugs, vagus nerve stimulation, and a partial callosotomy.</p><p>The patient had multiple types of seizures including drop attacks, absences, and tonic–clonic seizures. He tried vagus nerve stimulation for two years without success. Forced normalization developed after the vagus nerve stimulator was turned off.</p><p>This is the first case to our knowledge to describe forced normalization after turning off the vagus nerve stimulator.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"11 ","pages":"Pages 81-83"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2019.01.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36976521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Epileptic spasms as the presenting seizure type in a patient with a new “O” of TORCH, congenital Zika virus infection 先天性寨卡病毒感染TORCH新“O”型患者表现为癫痫性痉挛
Epilepsy and Behavior Case Reports Pub Date : 2019-01-01 DOI: 10.1016/j.ebcr.2018.09.002
Jason Lockrow, Hannah Tully, Russell P. Saneto
{"title":"Epileptic spasms as the presenting seizure type in a patient with a new “O” of TORCH, congenital Zika virus infection","authors":"Jason Lockrow,&nbsp;Hannah Tully,&nbsp;Russell P. Saneto","doi":"10.1016/j.ebcr.2018.09.002","DOIUrl":"10.1016/j.ebcr.2018.09.002","url":null,"abstract":"<div><p>Congenital TORCH infections are a significant cause of epileptic spasms, an infantile epileptic encephalopathy, through disruptions to several pathways in neurodevelopment. Congenital Zika virus has a similar neurotropism to other TORCH agents, and leads to microcephaly, severe neurodevelopmental impairment, and high rates of early onset seizures. Here we report a child with confirmed congenital Zika virus who developed extensor epileptic spasms and hypsarrhythmia associated with a loss of early developmental milestones. Early treatment led to resolution of epileptic spasms and improved developmental trajectory, though the child continues to have ongoing focal seizures and prominent developmental impairment. Congenital Zika virus infection requires close monitoring as early identification of epileptic spasms is likely important in long term developmental outcome.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"11 ","pages":"Pages 1-3"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2018.09.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36700168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Surgically treated intracranial supratentorial calcifying pseudoneoplasms of the neuraxis (CAPNON) with drug-resistant left temporal lobe epilepsy: A case report and review of the literature 手术治疗耐药左颞叶癫痫伴颅内幕上钙化性神经轴假性肿瘤1例报告及文献复习
Epilepsy and Behavior Case Reports Pub Date : 2019-01-01 DOI: 10.1016/j.ebcr.2019.02.002
Yuta Tanoue, Takehiro Uda, Kosuke Nakajo, Shugo Nishijima, Tsuyoshi Sasaki, Kenji Ohata
{"title":"Surgically treated intracranial supratentorial calcifying pseudoneoplasms of the neuraxis (CAPNON) with drug-resistant left temporal lobe epilepsy: A case report and review of the literature","authors":"Yuta Tanoue,&nbsp;Takehiro Uda,&nbsp;Kosuke Nakajo,&nbsp;Shugo Nishijima,&nbsp;Tsuyoshi Sasaki,&nbsp;Kenji Ohata","doi":"10.1016/j.ebcr.2019.02.002","DOIUrl":"10.1016/j.ebcr.2019.02.002","url":null,"abstract":"<div><p>Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare pathological lesions that can present anywhere in the central nervous system. Symptoms vary depending on the location, though they often include seizures, especially in intracranial and supratentorial lesions. A case of intracranial supratentorial CAPNON presenting with drug-resistant left temporal lobe epilepsy is reported. The patient had a history of drug-resistant focal seizures for over 36 years. The lesion was located in the left mesial temporal lobe, but hippocampal sclerosis and hippocampal invasion were not apparent. The lesion was removed without hippocampectomy, and the patient has been seizure-free for one year.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"11 ","pages":"Pages 107-114"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2019.02.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37296687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Epilepsy phenotype in patients with Xp22.31 microduplication Xp22.31微重复患者的癫痫表型
Epilepsy and Behavior Case Reports Pub Date : 2019-01-01 DOI: 10.1016/j.ebcr.2018.10.004
Mario Brinciotti , Francesca Fioriello , Antonio Mittica , Laura Bernardini , Marina Goldoni , Maria Matricardi
{"title":"Epilepsy phenotype in patients with Xp22.31 microduplication","authors":"Mario Brinciotti ,&nbsp;Francesca Fioriello ,&nbsp;Antonio Mittica ,&nbsp;Laura Bernardini ,&nbsp;Marina Goldoni ,&nbsp;Maria Matricardi","doi":"10.1016/j.ebcr.2018.10.004","DOIUrl":"10.1016/j.ebcr.2018.10.004","url":null,"abstract":"<div><p>The clinical significance of Xp22.31 microduplication is still unclear. We describe a family in which a mother and two children have Xp22.31 microduplication associated with different forms of epilepsy and epileptiform EEG abnormalities. The proband had benign epilepsy with centrotemporal spikes with dysgraphia and dyscalculia (IQ 72), the sister had juvenile myoclonic epilepsy, and both had bilateral talipes anomalies. The mother, who was the carrier of the microduplication, was asymptomatic. The asymptomatic father did not possess the microduplication. These data contribute to delineate the phenotype associated with Xp22.31 microduplication and suggest a potential pathogenic role for an epilepsy phenotype.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"11 ","pages":"Pages 31-34"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2018.10.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36872152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A case of ictal burst-suppression 致命突发抑制一例
Epilepsy and Behavior Case Reports Pub Date : 2019-01-01 DOI: 10.1016/j.ebcr.2018.11.005
Pegah Afra , Verena Clarissa Samara , Lilly Fagatele , Bola Adamolekun
{"title":"A case of ictal burst-suppression","authors":"Pegah Afra ,&nbsp;Verena Clarissa Samara ,&nbsp;Lilly Fagatele ,&nbsp;Bola Adamolekun","doi":"10.1016/j.ebcr.2018.11.005","DOIUrl":"10.1016/j.ebcr.2018.11.005","url":null,"abstract":"<div><p>“Burst-suppression” pattern consists of complete attenuation of background between bursts of mixed frequencies, variable morphology and waveforms. It is a subgroup of periodic patterns seen in severe cerebral damage, anesthesia or prematurity. Here, we present a 46-year-old woman with post-anoxic encephalopathy on cooling protocol with two electrographically similar patterns of burst-suppression (one with a clinical ictal correlate of isolated eye movements), as well as three electroclinical seizures. The literature on rare clinical phenomenon of isolated eye movements associated with burst-suppression is reviewed, with the conclusion that the presented case suggests an ictal origin.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"11 ","pages":"Pages 73-76"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2018.11.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36967240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Preserved evoked conscious perception of phosphenes with direct stimulation of deafferented primary visual cortex 通过直接刺激失传入的初级视觉皮层，保存诱发了有意识的光幻视知觉
Epilepsy and Behavior Case Reports Pub Date : 2019-01-01 DOI: 10.1016/j.ebcr.2018.12.002
Kelly L. Collins , Devapratim Sarma , Shahin Hakimian , Jeff J. Tsai , Jeffrey G. Ojemann
{"title":"Preserved evoked conscious perception of phosphenes with direct stimulation of deafferented primary visual cortex","authors":"Kelly L. Collins ,&nbsp;Devapratim Sarma ,&nbsp;Shahin Hakimian ,&nbsp;Jeff J. Tsai ,&nbsp;Jeffrey G. Ojemann","doi":"10.1016/j.ebcr.2018.12.002","DOIUrl":"10.1016/j.ebcr.2018.12.002","url":null,"abstract":"<div><p>The premise of neuro-rehabilitation after injury is to access the residual capacity of the nervous system to improve function. We describe a patient who developed a quadrantopsia and drug-resistant focal epilepsy after an arteriovenous malformation hemorrhage. Thirty years later, he underwent placement of subdural electrodes for seizure mapping. Phosphenes were elicited in the blind right visual field with stimulation of occipital cortex. This case demonstrates that visual cortex may retain functional organization after a partial subcortical visual pathway injury. This persistent conscious mapping suggests that disconnected visual cortex could serve as a region for interfacing with neural prosthetic devices for acquired blindness.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"11 ","pages":"Pages 84-86"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2018.12.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36975979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Autosomal dominant temporal lobe epilepsy associated with heterozygous reelin mutation: 3 T brain MRI study with advanced neuroimaging methods 常染色体显性颞叶癫痫与杂合型reelin突变相关:3 采用先进神经成像方法的T脑MRI研究
Epilepsy and Behavior Case Reports Pub Date : 2019-01-01 DOI: 10.1016/j.ebcr.2018.10.003
Katarína Česká , Štefánia Aulická , Ondřej Horák , Pavlína Danhofer , Pavel Říha , Radek Mareček , Jan Šenkyřík , Ivan Rektor , Milan Brázdil , Hana Ošlejšková
{"title":"Autosomal dominant temporal lobe epilepsy associated with heterozygous reelin mutation: 3 T brain MRI study with advanced neuroimaging methods","authors":"Katarína Česká ,&nbsp;Štefánia Aulická ,&nbsp;Ondřej Horák ,&nbsp;Pavlína Danhofer ,&nbsp;Pavel Říha ,&nbsp;Radek Mareček ,&nbsp;Jan Šenkyřík ,&nbsp;Ivan Rektor ,&nbsp;Milan Brázdil ,&nbsp;Hana Ošlejšková","doi":"10.1016/j.ebcr.2018.10.003","DOIUrl":"10.1016/j.ebcr.2018.10.003","url":null,"abstract":"<div><h3>Purpose</h3><p>Autosomal dominant lateral temporal epilepsy (ADLTE) is a genetic focal epilepsy syndrome characterized by focal seizures with dominant auditory symptomatology. We present a case report of an 18-year-old patient with acute onset of seizures associated with epilepsy. Based on the clinical course of the disease and the results of the investigation, the diagnosis of ADLTE with a proven mutation in the RELN gene, which is considered causative, was subsequently confirmed. The aim of this study was to use 3 Tesla (3 T) magnetic resonance imaging (MRI) and advanced neuroimaging methods in a patient with a confirmed diagnosis of ADTLE.</p></div><div><h3>Methods</h3><p>3 T MRI brain scan and advanced neuroimaging methods were used in the standard protocols to analyzse voxel-based MRI, cortical thickness, and functional connectivity.</p></div><div><h3>Results</h3><p>Morphometric MRI analysis (blurred grey-white matter junctions, voxel-based morphometry, and cortical thickness analysis) did not provide any informative results. The functional connectivity analysis revealed higher local synchrony in the patient in the left temporal (middle temporal gyrus), left frontal (supplementary motor area, superior frontal gyrus), and left parietal (gyrus angularis, gyrus supramarginalis) regions and the cingulate (middle cingulate gyrus) as compared to healthy controls.</p></div><div><h3>Conclusions</h3><p>Evidence of multiple areas of functional connectivity supports the theory of epileptogenic networks in ADTLE. Further studies are needed to elucidate this theory.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"11 ","pages":"Pages 39-42"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2018.10.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36832889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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