Sydney Lee , Alyssa Denton , Lady Diana Ladino , Karen Waterhouse , Aleksander Vitali , Jose Francisco Tellez-Zenteno
{"title":"lenox - gastaut综合征中关闭迷走神经刺激后的强迫正常化","authors":"Sydney Lee , Alyssa Denton , Lady Diana Ladino , Karen Waterhouse , Aleksander Vitali , Jose Francisco Tellez-Zenteno","doi":"10.1016/j.ebcr.2019.01.004","DOIUrl":null,"url":null,"abstract":"<div><p>Forced normalization is the development of psychiatric symptoms in a patient experiencing remission of seizures. We present a case of Lennox Gastaut syndrome in which forced normalization developed after vagus nerve stimulation was stopped.</p><p>The patient had drug resistant epilepsy and failed anti-seizure drugs, vagus nerve stimulation, and a partial callosotomy.</p><p>The patient had multiple types of seizures including drop attacks, absences, and tonic–clonic seizures. He tried vagus nerve stimulation for two years without success. Forced normalization developed after the vagus nerve stimulator was turned off.</p><p>This is the first case to our knowledge to describe forced normalization after turning off the vagus nerve stimulator.</p></div>","PeriodicalId":56365,"journal":{"name":"Epilepsy and Behavior Case Reports","volume":"11 ","pages":"Pages 81-83"},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ebcr.2019.01.004","citationCount":"6","resultStr":"{\"title\":\"Forced normalization after turning off vagus nerve stimulation in Lennox–Gastaut syndrome\",\"authors\":\"Sydney Lee , Alyssa Denton , Lady Diana Ladino , Karen Waterhouse , Aleksander Vitali , Jose Francisco Tellez-Zenteno\",\"doi\":\"10.1016/j.ebcr.2019.01.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Forced normalization is the development of psychiatric symptoms in a patient experiencing remission of seizures. We present a case of Lennox Gastaut syndrome in which forced normalization developed after vagus nerve stimulation was stopped.</p><p>The patient had drug resistant epilepsy and failed anti-seizure drugs, vagus nerve stimulation, and a partial callosotomy.</p><p>The patient had multiple types of seizures including drop attacks, absences, and tonic–clonic seizures. He tried vagus nerve stimulation for two years without success. Forced normalization developed after the vagus nerve stimulator was turned off.</p><p>This is the first case to our knowledge to describe forced normalization after turning off the vagus nerve stimulator.</p></div>\",\"PeriodicalId\":56365,\"journal\":{\"name\":\"Epilepsy and Behavior Case Reports\",\"volume\":\"11 \",\"pages\":\"Pages 81-83\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.ebcr.2019.01.004\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Epilepsy and Behavior Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2213323218301774\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Epilepsy and Behavior Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213323218301774","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Forced normalization after turning off vagus nerve stimulation in Lennox–Gastaut syndrome
Forced normalization is the development of psychiatric symptoms in a patient experiencing remission of seizures. We present a case of Lennox Gastaut syndrome in which forced normalization developed after vagus nerve stimulation was stopped.
The patient had drug resistant epilepsy and failed anti-seizure drugs, vagus nerve stimulation, and a partial callosotomy.
The patient had multiple types of seizures including drop attacks, absences, and tonic–clonic seizures. He tried vagus nerve stimulation for two years without success. Forced normalization developed after the vagus nerve stimulator was turned off.
This is the first case to our knowledge to describe forced normalization after turning off the vagus nerve stimulator.
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