Journal of Rheumatic Diseases最新文献_第3页

Macrophage activation syndrome in Kawasaki disease: a literature review of Korean studies. 川崎病巨噬细胞激活综合征：韩国研究的文献综述。

IF 2.2

Journal of Rheumatic Diseases Pub Date : 2025-04-01 Epub Date: 2025-02-03 DOI: 10.4078/jrd.2024.0118

Dae Chul Jeong, Soo-Young Lee

{"title":"Macrophage activation syndrome in Kawasaki disease: a literature review of Korean studies.","authors":"Dae Chul Jeong, Soo-Young Lee","doi":"10.4078/jrd.2024.0118","DOIUrl":"10.4078/jrd.2024.0118","url":null,"abstract":"Macrophage activation syndrome (MAS) is a rare but potentially life-threatening complication of Kawasaki disease (KD). In Korea, many studies on KD have been reported, but there are only a few studies on MAS complicating KD (MAS-KD). This study was conducted to provide the characteristics of MAS-KD patients in Korea through a literature review. A total of 23 Korean patients with MAS-KD from 10 papers were included in this study. All MAS-KD patients met the hemophagocytic lymphohistiocytosis (HLH)-2004 criteria and/or the 2016 MAS criteria. The incidence of MAS-KD in Korean children was 0.8%~1.1%, which is relatively low compared to North America (1.9%). MAS-KD patients had lower rates of KD-related features and higher rates of incomplete KD, coronary artery abnormalities, and intravenous immunoglobulin resistance than patients with KD without MAS. Notable laboratory abnormalities in MAS-KD include anemia, neutropenia, thrombocytopenia, hypoalbuminemia, increased hepatic transaminase levels, and hyperferritinemia. For treatment of MAS-KD, the HLH-2004 protocol (i.e., 40 weeks of complex chemotherapy) was applied to 15 patients (65%), which is a significantly greater than those treated with this protocol in other countries (35%). Two patients (9%) died during the HLH-2004 protocol. In actual practice, MAS may be underrecognized in patients with KD. Clinical suspicion is paramount for early diagnosis and timely treatment.","PeriodicalId":56161,"journal":{"name":"Journal of Rheumatic Diseases","volume":"32 2","pages":"105-112"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of novel cardiovascular risk calculators in patients with rheumatoid arthritis. 类风湿关节炎患者新型心血管风险计算器的评估。

IF 2.2

Journal of Rheumatic Diseases Pub Date : 2025-04-01 Epub Date: 2024-10-08 DOI: 10.4078/jrd.2024.0093

Dionicio Angel Galarza-Delgado, Valeria Gonzalez-Gonzalez, Natalia Guajardo-Jauregui, Jesus Alberto Cardenas-de la Garza, Rosa Icela Arvizu-Rivera, Maria Fernanda Elizondo-Benitez, Andrea Lizbeth Guajardo-Aldaco, Jose Ramon Azpiri-Lopez, Iris Jazmin Colunga-Pedraza

引用次数: 0

Circulating VEGF levels and genetic polymorphisms in Behçet's disease: a meta-analysis. 循环VEGF水平和behaperet病的遗传多态性：一项荟萃分析

IF 2.2

Journal of Rheumatic Diseases Pub Date : 2025-04-01 Epub Date: 2024-11-15 DOI: 10.4078/jrd.2024.0103

Young Ho Lee, Gwan Gyu Song

{"title":"Circulating VEGF levels and genetic polymorphisms in Behçet's disease: a meta-analysis.","authors":"Young Ho Lee, Gwan Gyu Song","doi":"10.4078/jrd.2024.0103","DOIUrl":"10.4078/jrd.2024.0103","url":null,"abstract":"Objective: This study aimed to explore the relationship between circulating vascular endothelial growth factor (VEGF) levels and Behçet's disease (BD), as well as to examine the association between VEGF gene polymorphisms and BD.Methods: We conducted a comprehensive search of the MEDLINE, Embase, and Web of Science databases to identify relevant research articles. A meta-analysis was performed to compare serum or plasma VEGF levels in BD patients with those in control groups. Additionally, we evaluated the potential associations between BD susceptibility and specific VEGF polymorphisms, namely -634 C/G, +936 C/T, and the 18 bp insertion/deletion (I/D) at -2549.Results: The analysis included 15 studies with a total of 1,020 BD patients and 1,031 controls. BD patients exhibited significantly higher circulating VEGF levels compared to controls (standardized mean difference [SMD]=1.726, 95% confidence interval [CI]=1.030~2.421, p<0.001). Elevated VEGF levels were noted among BD patients from European and Arab populations. Subgroup analysis further confirmed the increase in VEGF levels across different data types and sample sizes. Patients with active BD had higher VEGF levels than those with inactive BD (SMD=0.635, 95% CI=0.092~1.177, p=0.022). However, no significant association was found between BD and the VEGF -634 C allele (odds ratio=1.023, 95% CI=0.707~1.481, p=0.904). Similarly, no association was detected between BD and the VEGF +936 C/T or 18 bp I/D at -2549 polymorphisms.Conclusion: Our meta-analysis showed a strong association between elevated circulating VEGF levels and BD. However, the VEGF polymorphisms examined in this study do not appear to be associated with susceptibility to BD.","PeriodicalId":56161,"journal":{"name":"Journal of Rheumatic Diseases","volume":"32 2","pages":"122-129"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigating complexity through "the groove": eosinophilic fasciitis in the context of diabetes and lichen planus. 通过“沟槽”导航复杂性：糖尿病和扁平苔藓背景下的嗜酸性筋膜炎。

IF 2.2

Journal of Rheumatic Diseases Pub Date : 2025-04-01 Epub Date: 2025-03-10 DOI: 10.4078/jrd.2024.0135

Sukdev Manna

引用次数: 0

Rheumatoid arthritis and pain management: the significance of psychological factors. 类风湿关节炎与疼痛管理：心理因素的意义。

IF 2.2

Journal of Rheumatic Diseases Pub Date : 2025-04-01 Epub Date: 2025-03-06 DOI: 10.4078/jrd.2025.0022

Hyun-Ok Kim

引用次数: 0

Evaluation of 14-3-3eta protein as a diagnostic biomarker in the initial assessment of inflammatory arthritis. 14-3-3eta蛋白在炎性关节炎初始评估中的诊断性生物标志物评价

IF 2.2

Journal of Rheumatic Diseases Pub Date : 2025-04-01 Epub Date: 2024-12-04 DOI: 10.4078/jrd.2024.0110

Roshan Subedi, Afrah Misbah, Adnan Al Najada, Anthony James Ocon

{"title":"Evaluation of 14-3-3eta protein as a diagnostic biomarker in the initial assessment of inflammatory arthritis.","authors":"Roshan Subedi, Afrah Misbah, Adnan Al Najada, Anthony James Ocon","doi":"10.4078/jrd.2024.0110","DOIUrl":"10.4078/jrd.2024.0110","url":null,"abstract":"Objective: Serum 14-3-3eta are novel biomarkers of rheumatoid arthritis (RA). It is not clear whether 14-3-3eta may be present in other forms of inflammatory arthritis (IA). We evaluated the presence of 14-3-3eta as a diagnostic biomarker in the evaluation IA.Methods: A retrospective cohort study of adult patients who were evaluated for IA by a rheumatologist with a result for the lab test of 14-3-3eta was conducted.Results: Of 280 included patients, 30% were diagnosed with RA, 11% with psoriatic arthritis (PsA), and 59% with another condition. Twenty-four (9%) patients had positive results for 14-3-3eta. Fifty-two percent of positive patients were diagnosed with RA, with 48% having another diagnosis including axial spondyloarthritis, gout, Sjögren's, undifferentiated IA, diabetic cheiroarthropathy, prostate cancer with bone metastasis, osteoarthritis, unspecified arthralgia. No patients with PsA had a positive value. RA patients had a higher value for 14-3-3eta compared to non-RA (5.44 [1.56~9.31] vs. 0.69 [0.40~0.98] ng/mL, p=0.03, square brackets are 95% confidence interval values). The mean value for the 14-3-3eta in seropositive RA trended higher than seronegative (8.0 [2.3~13.7] vs. 1.4 [0.4~2.4] ng/mL, p=0.06). In the RA cohort, elevated 14-3-3eta was associated with elevated erythrocyte sedimentation rate (odd ratio=6.62 [1.24~47.09], p<0.04), but not other variables.Conclusion: 14-3-3eta may aid as a diagnostic biomarker of RA. However, it is not specific for RA, especially at low positive levels, and may be positive in other forms of IA. Ideal cutoff values need to be established for RA and non-RA conditions. It was not found in PsA.","PeriodicalId":56161,"journal":{"name":"Journal of Rheumatic Diseases","volume":"32 2","pages":"130-135"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931278/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of disease-related indicators on pain measures in rheumatoid arthritis: a biopsychosocial perspective. 疾病相关指标对类风湿关节炎疼痛测量的影响：生物心理社会视角

IF 2.2

Journal of Rheumatic Diseases Pub Date : 2025-01-01 Epub Date: 2024-09-04 DOI: 10.4078/jrd.2024.0074

Hee Jun Kim, Ju-Yang Jung, Ji-Won Kim, Chang-Hee Suh, Hyoun-Ah Kim

{"title":"Impact of disease-related indicators on pain measures in rheumatoid arthritis: a biopsychosocial perspective.","authors":"Hee Jun Kim, Ju-Yang Jung, Ji-Won Kim, Chang-Hee Suh, Hyoun-Ah Kim","doi":"10.4078/jrd.2024.0074","DOIUrl":"10.4078/jrd.2024.0074","url":null,"abstract":"Objective: Pain is a significant and debilitating symptom of rheumatoid arthritis (RA) that significantly affects the quality of life and functional ability of patients. In the present study, we examined the association between pain variables and disease activity markers in patients with RA.Methods: We enrolled 133 patients with RA and assessed their clinical characteristics, socioeconomic and psychological factors, and pain measures. The psychological factors assessed included depressive symptoms and pain catastrophizing.Results: The study cohort comprised predominantly female patients with RA with an average age of 55.5±10.1 years. Depressive symptoms had a mean score of 5.83±4.71, while pain catastrophizing had an average score of 14.36±10.70. The mean scores for pain intensity, and pain interference, were 2.98±1.75 and 19.54±16.17, respectively, with significant positive correlations observed with depressive symptoms. Hemoglobin and hematocrit levels were negatively correlated with pain intensity. Multivariable linear regression analysis revealed significant associations between depressive symptoms and pain intensity, catastrophizing, and interference. Other factors associated with pain intensity included tender joint count. Pain catastrophizing was associated with education and economic status. Pain interference was associated with sex and economic status.Conclusion: This study shows the influence of disease-related indicators and psychological factors on pain in patients with RA, with depressive symptoms playing a crucial role in predicting pain experience. Effective pain management strategies for RA should include the management of depressive symptoms, in addition to addressing disease-related indicators.","PeriodicalId":56161,"journal":{"name":"Journal of Rheumatic Diseases","volume":"32 1","pages":"38-47"},"PeriodicalIF":2.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of Curcuma longa in relieving pain symptoms of knee osteoarthritis patients: a systematic review and meta-analysis of clinical trials. 姜黄缓解膝骨关节炎患者疼痛症状的疗效：临床试验的系统回顾和荟萃分析。

IF 2.2

Journal of Rheumatic Diseases Pub Date : 2025-01-01 Epub Date: 2024-11-06 DOI: 10.4078/jrd.2024.0062

Rudy Hidayat, Faisal Parlindungan, Jihan Izzatun Nisa, Arya Ivan Mahendra, Muhammad Izza Indika, Cristopher Efendi

{"title":"Efficacy of Curcuma longa in relieving pain symptoms of knee osteoarthritis patients: a systematic review and meta-analysis of clinical trials.","authors":"Rudy Hidayat, Faisal Parlindungan, Jihan Izzatun Nisa, Arya Ivan Mahendra, Muhammad Izza Indika, Cristopher Efendi","doi":"10.4078/jrd.2024.0062","DOIUrl":"10.4078/jrd.2024.0062","url":null,"abstract":"Objective: Osteoarthritis (OA), particularly knee OA, affects 24% of adults and is a significant cause of disability. Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used but have many adverse effects. Antioxidant and anti-iflammatory properties of Curcuma longa might decrease pain thus improving joint function.Methods: This systematic review and meta-analysis evaluated randomized controlled trials (RCTs) on Curcuma longa efficacy for knee OA. We reported mean differences (MD) with 95% confidence interval (CI) for continuous outcomes and evaluated Visual Analog Scale (VAS) for pain and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) total score over 4 to 6 weeks for treatment effects.Results: Ten RCTs with 786 patients were included. Curcuma longa significantly improved VAS for pain than placebo (MD 18.25, 95% CI 7.79 to 28.72, p=0.0006). It was not inferior to NSAIDs in WOMAC total score improvement (MD -11.99, 95% CI -39.21 to 15.23, p=0.39). Both dosages (<1,000 and ≥1,000 mg/day) of Curcuma longa demonstrated similar improvement in VAS for pain compared to placebo (MD 27.02, 95% CI 1.45 to 52.60, p=0.04; MD 21.48, 95% CI 1.78 to 41.18, p=0.03).Conclusion: Curcuma longa benefits knee OA pain and function, being more effective than placebo and comparable to NSAIDs. Despite positive results, limitation and heterogeneity of the studies necessitates further research to explore optimal dosages and administration methods of Curcuma longa as therapeutic option for knee OA.","PeriodicalId":56161,"journal":{"name":"Journal of Rheumatic Diseases","volume":"32 1","pages":"17-29"},"PeriodicalIF":2.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization of biological therapy selection in rheumatoid arthritis: insights into anemia and interleukin-6 pathway. 类风湿关节炎生物治疗选择的优化：贫血和白细胞介素-6通路的见解。

IF 2.2

Journal of Rheumatic Diseases Pub Date : 2025-01-01 Epub Date: 2024-12-13 DOI: 10.4078/jrd.2024.0133

Bora Nam

引用次数: 0

Erratum: Implication of serious infections in patients with antineutrophil cytoplasmic antibody-associated vasculitis for the first cycle of rituximab: a pilot study in a single Korean center. 更正：利妥昔单抗第一个周期的抗中性粒细胞细胞质抗体相关血管炎患者严重感染的含义：一个韩国中心的试点研究。

IF 2.2

Journal of Rheumatic Diseases Pub Date : 2025-01-01 DOI: 10.4078/jrd.22.0033E

Hyunsue Do, Jung Yoon Pyo, Jason Jungsik Song, Yong-Beom Park, Sang-Won Lee

引用次数: 0