Life-Basel最新文献_第10页

Rapid and Accurate Ecotoxicological Assessment of Heavy Metals Using Cyprinus carpio Cells. 利用鲤鱼细胞对重金属进行快速准确的生态毒理学评估

IF 3.2 3区生物学

Life-Basel Pub Date : 2024-09-05 DOI: 10.3390/life14091119

Yun Haeng Lee, Myeong Uk Kuk, Ji Ho Park, Hojun Lee, Haneur Lee, Moon Kyoung So, Jee Hee Yoon, Yoo Jin Lee, Duyeol Kim, Byeonghyeon So, Minseon Kim, Jihae Park, Taejun Han, Joon Tae Park

{"title":"Rapid and Accurate Ecotoxicological Assessment of Heavy Metals Using Cyprinus carpio Cells.","authors":"Yun Haeng Lee, Myeong Uk Kuk, Ji Ho Park, Hojun Lee, Haneur Lee, Moon Kyoung So, Jee Hee Yoon, Yoo Jin Lee, Duyeol Kim, Byeonghyeon So, Minseon Kim, Jihae Park, Taejun Han, Joon Tae Park","doi":"10.3390/life14091119","DOIUrl":"https://doi.org/10.3390/life14091119","url":null,"abstract":"Heavy metals have serious negative effects on various aquatic organisms, and therefore rapid and accurate ecotoxicological assessments of heavy metals are necessary. Fish-derived cells sensitive to heavy metals have been used as valuable tools for ecotoxicological assessments. However, this method requires a minimum toxicity treatment time of 96 h, which limits its use when rapid ecotoxicological assessments are required or ecotoxicological assessments of a large number of toxicants are performed. In this study, these limitations were overcome by adjusting parameters including the concentration of fetal bovine serum (FBS) in the medium and the treatment time of the toxicant. Specifically, we found that the maximum time for fish cells to remain unstarved was 6 h when using a medium containing 1% FBS. We applied both parameters to the ecotoxicological assessment (using a medium containing 1% FBS for the toxicity assessment and treating the toxicant for only 6 h). Surprisingly, these adjusted parameters allowed us to obtain faster and more accurate data than the traditional assessment. This improvement was due to the new assessment conditions that minimized the possibility that the growth-inducing effects of nutrients present in excess in the medium could interfere with the cellular response to the toxicant. The accuracy of this assessment was not limited to measuring the toxicity of heavy metals. In conclusion, we have established an ecotoxicity assessment that can generate rapid and accurate data on heavy metals. This new platform will become the cornerstone of rapid and accurate ecotoxicity assessments of heavy metals.","PeriodicalId":56144,"journal":{"name":"Life-Basel","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11432982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Clavien-Dindo Classification for Body-Contouring Surgery Complications: Evaluation of 602 Cases. 身体整形手术并发症的 Clavien-Dindo 分类：对 602 个病例的评估

IF 3.2 3区生物学

Life-Basel Pub Date : 2024-09-05 DOI: 10.3390/life14091120

Michael S Pollhammer, Dominik Duscher, Andrea Pagani, Maximilian Zaussinger, Raphael Wenny, Isabel Zucal, Manfred Schmidt, Lukas Prantl, Georg M Huemer

{"title":"The Clavien-Dindo Classification for Body-Contouring Surgery Complications: Evaluation of 602 Cases.","authors":"Michael S Pollhammer, Dominik Duscher, Andrea Pagani, Maximilian Zaussinger, Raphael Wenny, Isabel Zucal, Manfred Schmidt, Lukas Prantl, Georg M Huemer","doi":"10.3390/life14091120","DOIUrl":"https://doi.org/10.3390/life14091120","url":null,"abstract":"Background: Due to the high frequency of postoperative complications after body-contouring surgeries, the need for a unifying postoperative complication grading system that correlates with outcomes is of key importance. Here we therefore consider the application of the Clavien-Dindo classification to evaluate postoperative complications after body-contouring surgeries. Methods: A retrospective study on 602 patients who underwent body-contouring surgery between 2009 and 2015 at our institution was performed. The length of hospital stays, age, sex, follow-up visits, and postoperative complications were evaluated and classified using the Clavien-Dindo classification. Results: We raised a total of 672 body-contouring procedures on 602 patients (563 female, 39 male). According to the Clavien-Dindo System, the severity of postoperative complications following body-contouring procedures was significantly correlated with the duration of hospitalization (mean 5.8 ± 2.7 days) and the number of follow-up visits (mean 4.4 ± 4.7). Conclusions: The Clavien-Dindo classification offers a valid prediction for postoperative hospital stay and the number of follow-up visits after body-reshaping surgery. By becoming a validated and reliable grading system that correlates patients' outcomes after body-contouring procedures, this classification has the potential to significantly improve patients' healthcare and quality of life.","PeriodicalId":56144,"journal":{"name":"Life-Basel","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11432988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142336703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Home-Based Cardiac Rehabilitation with Optimized Exercise Prescriptions Using a Mobile Healthcare App in Patients with Acute Myocardial Infarction: A Randomized Controlled Trial. 急性心肌梗死患者使用移动医疗应用程序优化运动处方进行家庭心脏康复的效果：随机对照试验

IF 3.2 3区生物学

Life-Basel Pub Date : 2024-09-05 DOI: 10.3390/life14091122

Hyun-Seok Jo, Hyeong-Min Kim, Chae-Hyun Go, Hae-Young Yu, Hyeng-Kyu Park, Jae-Young Han

{"title":"Effectiveness of Home-Based Cardiac Rehabilitation with Optimized Exercise Prescriptions Using a Mobile Healthcare App in Patients with Acute Myocardial Infarction: A Randomized Controlled Trial.","authors":"Hyun-Seok Jo, Hyeong-Min Kim, Chae-Hyun Go, Hae-Young Yu, Hyeng-Kyu Park, Jae-Young Han","doi":"10.3390/life14091122","DOIUrl":"https://doi.org/10.3390/life14091122","url":null,"abstract":"Background: Despite the effectiveness of cardiac rehabilitation (CR), the actual participation rate in CR is low. While home-based CR offers a viable alternative, it faces challenges in participation due to factors such as a lack of self-motivation and fear of exercising without supervision. Utilizing a mobile healthcare application (app) during counseling may be an effective strategy for patients. Therefore, the aim of this study was to assess whether 6 weeks of home-based CR with exercise readjustment using a mobile app is an effective therapy for patients with acute myocardial infarction (AMI).Methods: Post-AMI patients eligible for home-based CR were randomized into the intervention group (CR-Mobile) and the control group, which followed the usual home-based CR protocol (CR-Usual). Both groups participated in a 6-week home-based CR program, with exercise readjustment and encouragement carried out every 2 weeks. The CR-Mobile group was supervised using data recorded in the mobile app, while the CR-Usual group was supervised via phone consultations. The primary outcome measured was maximal oxygen consumption (VO2max).Results: Within-group comparisons showed significant improvements in VO2max (PCR-Mobile = 0.011 vs. PCR-Usual = 0.020) and METs (PCR-Mobile = 0.011 vs. PCR-Usual = 0.011) for both groups.Conclusions: These findings suggest that a 6-week home-based CR program with exercise readjustment using a mobile app can potentially enhance exercise capacity as effectively as verbal supervision.","PeriodicalId":56144,"journal":{"name":"Life-Basel","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11433441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RETRACTED: Di Paola et al. Assessment of 2-Pentadecyl-2-oxazoline Role on Lipopolysaccharide-Induced Inflammation on Early Stage Development of Zebrafish (Danio rerio). Life 2022, 12, 128. 转载：Di Paola 等人，《2-十五烷基-2-噁唑啉对脂多糖诱发的斑马鱼（Danio rerio）早期发育阶段炎症的作用评估》。生命 2022，12，128。

IF 3.2 3区生物学

Life-Basel Pub Date : 2024-09-05 DOI: 10.3390/life14091115

Davide Di Paola, Sabrina Natale, Enrico Gugliandolo, Marika Cordaro, Rosalia Crupi, Rosalba Siracusa, Ramona D'Amico, Roberta Fusco, Daniela Impellizzeri, Salvatore Cuzzocrea, Nunziacarla Spanò, Fabio Marino, Alessio Filippo Peritore

引用次数: 0

Methods for Screening and Isolating Extremely Heat-Resistant Escherichia coli from Meat Sources. 从肉类来源中筛选和分离耐热性极强的大肠杆菌的方法。

IF 3.2 3区生物学

Life-Basel Pub Date : 2024-09-05 DOI: 10.3390/life14091123

Manita Guragain, Gregory E Smith, Joseph M Bosilevac

{"title":"Methods for Screening and Isolating Extremely Heat-Resistant Escherichia coli from Meat Sources.","authors":"Manita Guragain, Gregory E Smith, Joseph M Bosilevac","doi":"10.3390/life14091123","DOIUrl":"https://doi.org/10.3390/life14091123","url":null,"abstract":"Meat animals harbor diverse E. coli populations in their digestive tracts and can serve as sources of pathogenic E. coli. The consumption of meat and produce contaminated with virulent E. coli from animal sources is associated with human illnesses and outbreaks. Heat treatment is an antimicrobial intervention that is commonly used during meat processing to ensure effective reductions in microbial load. Extreme heat resistance (XHR) has been reported among meat-borne E. coli and is mainly attributed to an ~15-19 kb genetic element known as the transmissible locus of stress tolerance (tLST). XHR E. coli can resist treatments used during meat processing and cooking. Therefore, the detection of heat-resistant E. coli is important for devising effective control measures to prevent meat spoilage and ensure meat safety. Here, we present methods used to (1) screen for tLST genes by multiplex PCR and (2) screen and isolate XHR E. coli from meat sources. The mode of heat exposure affects the outcome of XHR testing. Hence, the protocols were optimized to achieve maximum agreement between the tLST genotype and the XHR phenotype.","PeriodicalId":56144,"journal":{"name":"Life-Basel","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11432786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computed Tomography and Fluorescence Spectroscopy Blood Plasma Analysis Study for Kynurenic Acid as a Diagnostic Approach to Chronic Coenurosis in Sheep. 以计算机断层扫描和荧光光谱血浆分析法研究犬尿氨酸作为绵羊慢性神经衰弱的诊断方法

IF 3.2 3区生物学

Life-Basel Pub Date : 2024-09-05 DOI: 10.3390/life14091121

Loredana Elena Olar, Vasile Daniel Tomoiagă, Sorin Marian Mârza, Ionel Papuc, Ioan Florin Beteg, Petru Cosmin Peștean, Mihai Musteață, Caroline Maria Lăcătuș, Raluca Marica, Paula Maria Pașca, Robert Cristian Purdoiu, Radu Lăcătuș

{"title":"Computed Tomography and Fluorescence Spectroscopy Blood Plasma Analysis Study for Kynurenic Acid as a Diagnostic Approach to Chronic Coenurosis in Sheep.","authors":"Loredana Elena Olar, Vasile Daniel Tomoiagă, Sorin Marian Mârza, Ionel Papuc, Ioan Florin Beteg, Petru Cosmin Peștean, Mihai Musteață, Caroline Maria Lăcătuș, Raluca Marica, Paula Maria Pașca, Robert Cristian Purdoiu, Radu Lăcătuș","doi":"10.3390/life14091121","DOIUrl":"https://doi.org/10.3390/life14091121","url":null,"abstract":"Coenurosis is a parasitic disease caused by the larval stage of Taenia multiceps, Coenurus cerebralis, typically found in the central nervous system of different livestock such as sheep and goats. The blood plasma from fifteen clinically healthy sheep and six sheep with neurological symptoms was studied by fluorescence spectroscopy in order to establish the contribution of kynurenic acid (KYNA), the neuroprotective metabolite of the kynurenine pathway, to the total fluorescence of the plasma. CT scans were used to confirm the presence of cysts in the central nervous system of sheep with neurological symptoms. The fluorescence spectroscopy analysis and further spectra deconvolution process revealed some significantly lower KYNA contributions to the total plasma fluorescence in sheep with coenurosis compared to healthy controls. Our results indicate that KYNA emission parameters could serve as valuable diagnostic markers, particularly for detecting preclinical cases of coenurosis, thus allowing for improved farm management practices.","PeriodicalId":56144,"journal":{"name":"Life-Basel","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11433226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Sister Species for the Blue Crab, Callinectes sapidus? A Tale Revealed by Mitochondrial DNA. 蓝蟹的姊妹物种？线粒体 DNA 揭示的一个故事

IF 3.2 3区生物学

Life-Basel Pub Date : 2024-09-05 DOI: 10.3390/life14091116

Chiara Locci, Ilenia Azzena, Noemi Pascale, Alessandra Ciccozzi, Ilaria Deplano, Ioannis A Giantsis, Dimitrios K Papadopoulos, Athanasios Lattos, Flavio Orrù, Cesare M Puzzi, Fabio Scarpa, Marco Casu, Daria Sanna

{"title":"A Sister Species for the Blue Crab, Callinectes sapidus? A Tale Revealed by Mitochondrial DNA.","authors":"Chiara Locci, Ilenia Azzena, Noemi Pascale, Alessandra Ciccozzi, Ilaria Deplano, Ioannis A Giantsis, Dimitrios K Papadopoulos, Athanasios Lattos, Flavio Orrù, Cesare M Puzzi, Fabio Scarpa, Marco Casu, Daria Sanna","doi":"10.3390/life14091116","DOIUrl":"https://doi.org/10.3390/life14091116","url":null,"abstract":"The Atlantic blue crab, Callinectes sapidus, is acknowledged as one of the worst invasive alien species in the Mediterranean, impacting biodiversity and human activities. Native to the western Atlantic, it has expanded to European coastal waters since the early 1900s. Despite its ecological and commercial importance, genetic research on this species is limited. Here we show a comprehensive investigation of the genetic variation and evolutionary history in Callinectes sapidus using 667 mitochondrial COI gene sequences. Our dataset encompasses 36 newly generated sequences from previously understudied Mediterranean sites and 631 from worldwide locations obtained from the GenBank public database. Our findings reveal two distinct, but closely related, genetic groups within the species' distribution range, suggesting the occurrence of a potential species complex. Furthermore, in the Mediterranean, low levels of genetic variability were observed except for substantial haplotypic differentiation in Turkish samples. This study depicts the global genetic diversity and evolutionary patterns of Callinectes sapidus, offering new insights into the taxonomic status of the species.","PeriodicalId":56144,"journal":{"name":"Life-Basel","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11433012/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular Characterization, Evolution and Expression Analysis of Ammonium Transporter from Four Closely Related Bactrocera Species (Tephritidae). 四种亲缘关系很近的栉水母（Tephritidae）铵转运体的分子特征、进化和表达分析。

IF 3.2 3区生物学

Life-Basel Pub Date : 2024-09-04 DOI: 10.3390/life14091114

Jie Zhang, Qi Wang, Chenhao Liu, Jiaying Liu, Qian Qian, Chuanjian Ru, Leyuan Liu, Shanchun Yan, Wei Liu, Guirong Wang

{"title":"Molecular Characterization, Evolution and Expression Analysis of Ammonium Transporter from Four Closely Related Bactrocera Species (Tephritidae).","authors":"Jie Zhang, Qi Wang, Chenhao Liu, Jiaying Liu, Qian Qian, Chuanjian Ru, Leyuan Liu, Shanchun Yan, Wei Liu, Guirong Wang","doi":"10.3390/life14091114","DOIUrl":"https://doi.org/10.3390/life14091114","url":null,"abstract":"Numerous insects are attracted to low levels of ammonia, utilizing it as a cue to locate food sources. The Ammonium Transporter (Amt), a highly conserved, atypical olfactory receptor, has been shown to mediate the detection of ammonia in insects. While the attraction of Tephritidae to ammonia is well established, knowledge about the Amt in this family is limited. The species Bactrocera dorsalis (Hendel 1912), Bactrocera cucurbitae (Coquillett 1899), Bactrocera correcta Bezzi 1916 and Bactrocera tau (Walker 1849), which are common agricultural pests within Tephritidae, exhibit numerous ecological similarities, offering a solid foundation for studying Amt characteristics in this family. In this study, we elucidated the sequences, evolutionary relationships, and expression patterns of Amt in these four species. The results indicated that these Amts share the same open reading frame, containing 1770 bp that encode a protein of 589 amino acid residues. These Amt proteins exhibit the typical structural characteristics of Amts, including an 11-transmembrane domain with an extracellular N-terminus and an intracellular C-terminus. They also have the ability to form trimers in the membrane. Additionally, they contain three conserved amino acid residues essential for ammonia transport: A189, H195, and H352. Phylogenetic and expression pattern analyses showed that they are highly conserved in Diptera and are significantly expressed in antennae. This study is the first report characterizing the Amt gene in four Tephritidae species. These findings provide a foundation for further exploration into the roles of these genes in their particular biological contexts.","PeriodicalId":56144,"journal":{"name":"Life-Basel","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11433543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MR Imaging of Hemosiderin Deposition in the Ankle Joints of Patients with Haemophilia: The Contribution of a Multi-Echo Gradient-Echo Sequence-Correlation with Osteochondral Changes and the Number and Chronicity of Joint Bleeds. 血友病患者踝关节血色素沉积的磁共振成像：多回波梯度回波序列的贡献--与骨软骨变化及关节出血数量和慢性程度的相关性。

IF 3.2 3区生物学

Life-Basel Pub Date : 2024-09-04 DOI: 10.3390/life14091112

Olympia Papakonstantinou, Efstratios Karavasilis, Epaminondas Martzoukos, Georgios Velonakis, Nikolaos Kelekis, Helen Pergantou

{"title":"MR Imaging of Hemosiderin Deposition in the Ankle Joints of Patients with Haemophilia: The Contribution of a Multi-Echo Gradient-Echo Sequence-Correlation with Osteochondral Changes and the Number and Chronicity of Joint Bleeds.","authors":"Olympia Papakonstantinou, Efstratios Karavasilis, Epaminondas Martzoukos, Georgios Velonakis, Nikolaos Kelekis, Helen Pergantou","doi":"10.3390/life14091112","DOIUrl":"https://doi.org/10.3390/life14091112","url":null,"abstract":"We aim (a) to introduce an easy-to-perform multi-echo gradient-echo sequence (mGRE) for the detection of hemosiderin deposition in the ankle joints of boys with haemophilia (b) to explore the associations between the presence and severity of hemosiderin deposition and the other components of haemophilic arthropathy, the clinical score, and the number and chronicity of joint bleeds. An MRI of 41 ankle joints of 21 haemophilic boys was performed on a 3 T MRI system using an mGRE sequence in addition to the conventional protocol. Conventional MRI and mGRE were separately and independently assessed by three readers, namely, two musculoskeletal radiologists and a general radiologist for joint hemosiderin. We set as a reference the consensus reading of the two musculoskeletal radiologists, who also evaluated the presence of synovial thickening, effusion, and osteochondral changes. Excellent inter-reader agreement was obtained using the mGRE sequence compared to the conventional protocol (ICC: 0.95-0.97 versus 0.48-0.89), with superior sensitivity (90-95% versus 50-85%), specificity (95.2-100% versus 76.2-95.2%), and positive (95-100% versus 71-94.4%) and negative predictive value (91.3-95.5% versus 87-63%). Hemosiderin deposition was associated with osteochondral changes, synovial thickening, clinical score, and the total number of ankle bleeds, while it was inversely related with the time elapsed between the last joint bleed and MRI. (p < 0.05). The application of an mGRE sequence significantly improved hemosiderin detection, even when performed by the less experienced reader. Joint hemosiderin deposition was associated with the other components of haemophilic arthropathy and was mostly apparent in recent joint bleeds.","PeriodicalId":56144,"journal":{"name":"Life-Basel","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11433466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimizing Femoral Access in Emergency EVAR with a Decision-Making Algorithm. 利用决策算法优化急诊 EVAR 中的股骨入路。

IF 3.2 3区生物学

Life-Basel Pub Date : 2024-09-04 DOI: 10.3390/life14091113

Domenico Mirabella, Salvatore Bruno, Manfredi Agostino La Marca, Ettore Dinoto, Edoardo Rodriquenz, Andrea Miccichè, Felice Pecoraro

{"title":"Optimizing Femoral Access in Emergency EVAR with a Decision-Making Algorithm.","authors":"Domenico Mirabella, Salvatore Bruno, Manfredi Agostino La Marca, Ettore Dinoto, Edoardo Rodriquenz, Andrea Miccichè, Felice Pecoraro","doi":"10.3390/life14091113","DOIUrl":"https://doi.org/10.3390/life14091113","url":null,"abstract":"Endovascular aneurysm repair (EVAR) has become the preferred approach over open repair for abdominal aortic aneurysms (AAAs) due to its minimally invasive nature. The common femoral artery (CFA) is the main access vessel for EVAR, with both surgical exposure and percutaneous access being utilized. However, in emergent cases, percutaneous access can be challenging and may result in complications such as bleeding or dissection thrombosis, leading to the need for surgical conversion. This study aimed to share experiences in implementing a decision-making algorithm to reduce surgical conversions due to percutaneous access failures. A total of 74 aortic patients treated with EVAR in emergency settings were included in this retrospective study. This study focused on various outcomes such as perioperative mortality, morbidity, procedure time, surgical exposure time, and surgical conversion rate. After the implementation of the decision-making algorithm, decreases in surgical conversions and operating time were observed. Percutaneous access was found to be more challenging in cases with specific anatomical characteristics of the CFA, such as severe atherosclerosis or smaller vessel diameter. This study highlighted the importance of carefully assessing patient anatomical features and utilizing a decision-making algorithm to optimize outcomes in EVAR procedures. Further research is needed to continue improving practices for managing aortic aneurysms and reducing complications in femoral artery access approaches.","PeriodicalId":56144,"journal":{"name":"Life-Basel","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11433623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0