Physica Medica-European Journal of Medical Physics最新文献

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Personalised patient dosimetry in C-arm CBCT: A preliminary study c臂CBCT个体化患者剂量测定:初步研究
IF 2.7 3区 医学
Physica Medica-European Journal of Medical Physics Pub Date : 2025-10-01 DOI: 10.1016/j.ejmp.2025.105136
Nina McWilliams , Seán Cournane , Jackie McCavana , Luis León Vintró
{"title":"Personalised patient dosimetry in C-arm CBCT: A preliminary study","authors":"Nina McWilliams , Seán Cournane , Jackie McCavana , Luis León Vintró","doi":"10.1016/j.ejmp.2025.105136","DOIUrl":"10.1016/j.ejmp.2025.105136","url":null,"abstract":"","PeriodicalId":56092,"journal":{"name":"Physica Medica-European Journal of Medical Physics","volume":"138 ","pages":"Article 105136"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145361639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A multi-site optimisation strategy for adult CT examinations 成人CT检查的多位点优化策略
IF 2.7 3区 医学
Physica Medica-European Journal of Medical Physics Pub Date : 2025-10-01 DOI: 10.1016/j.ejmp.2025.105107
Dara Ó’ Gallchobhair, Patrick Monnelly, Aidan Meehan
{"title":"A multi-site optimisation strategy for adult CT examinations","authors":"Dara Ó’ Gallchobhair, Patrick Monnelly, Aidan Meehan","doi":"10.1016/j.ejmp.2025.105107","DOIUrl":"10.1016/j.ejmp.2025.105107","url":null,"abstract":"","PeriodicalId":56092,"journal":{"name":"Physica Medica-European Journal of Medical Physics","volume":"138 ","pages":"Article 105107"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145362373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimation liver radiomics from postmortem CT: Development of interpretable models for postmortem interval estimation 从死后CT估计肝脏放射组学:发展可解释的死后间隔估计模型。
IF 2.7 3区 医学
Physica Medica-European Journal of Medical Physics Pub Date : 2025-10-01 DOI: 10.1016/j.ejmp.2025.105186
Fabio De-Giorgio , Davide Cusumano , Luca Vellini , Roberto Gatta , Luca Boldrini , Matteo Mancino , Michail E. Klontzas , Elena F. Kranioti , Evis Sala , Vincenzo L. Pascali
{"title":"Estimation liver radiomics from postmortem CT: Development of interpretable models for postmortem interval estimation","authors":"Fabio De-Giorgio ,&nbsp;Davide Cusumano ,&nbsp;Luca Vellini ,&nbsp;Roberto Gatta ,&nbsp;Luca Boldrini ,&nbsp;Matteo Mancino ,&nbsp;Michail E. Klontzas ,&nbsp;Elena F. Kranioti ,&nbsp;Evis Sala ,&nbsp;Vincenzo L. Pascali","doi":"10.1016/j.ejmp.2025.105186","DOIUrl":"10.1016/j.ejmp.2025.105186","url":null,"abstract":"<div><h3>Introduction</h3><div>Postmortem computed tomography (PMCT) is increasingly used in forensic investigations, offering a non-invasive and objective approach to estimating the postmortem interval (PMI). This study aimed to develop and externally validate radiomic models to distinguish deaths within versus beyond 24 h, using liver radiomic features from PMCT scans..</div></div><div><h3>Methods</h3><div>A retrospective analysis was performed on 51 cadavers for model development and validated on 80 independent cases. In the training set, 173 PMCT scans across different PMIs were analyzed. The liver was manually segmented, and 40 radiomic features—statistical, morphological, and fractal—were extracted. Robustness to segmentation variability was assessed with autocontoured segmentations using the Intraclass Correlation Coefficient (ICC). PMI was dichotomized as ≤ 24 versus &gt; 24 h. Univariate analyses identified predictive features, and logistic regression models were built from significant variables. Model performance was evaluated with receiver operating characteristic (ROC) curves, with sensitivity and specificity at the optimal threshold.</div></div><div><h3>Results</h3><div>Four features were significantly associated with PMI, with liver skewness emerging as the most predictive (p = 9.13 × 10<sup>−4</sup>) and robust (ICC = 0.75). A logistic regression model based on skewness achieved an AUC of 0.75 (95 % CI: 0.65–0.86) and 100 % specificity at the optimal threshold, reliably identifying deaths beyond 24 h. Adding a second feature did not improve performance (p = 0.54, DeLong test). External validation confirmed specificity of the skewness model (70 % at the optimal threshold).</div></div><div><h3>Conclusion</h3><div>Liver skewness extracted from PMCT shows potential as a biomarker for identifying deaths beyond 24 h, with performance confirmed on an independent cohort.</div></div>","PeriodicalId":56092,"journal":{"name":"Physica Medica-European Journal of Medical Physics","volume":"138 ","pages":"Article 105186"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design and validation of an integrated reference dosimetry and monitoring system for ultra-high dose-rate proton beams ranging from 20 Gy/s to 230 Gy/s 20 Gy/s至230 Gy/s超高剂量率质子束综合参考剂量测定与监测系统的设计与验证
IF 2.7 3区 医学
Physica Medica-European Journal of Medical Physics Pub Date : 2025-10-01 DOI: 10.1016/j.ejmp.2025.105187
Giada Petringa, Roberto Catalano, Antonino Amato, Antonio Domenico Russo, Giuseppe Francesco Fustaino, Mariacristina Guarrera, Giacomo Cuttone, Gustavo Esteban Messina, Luigi Raffaele, Alfio Domenico Pappalardo, Giuseppe Antonio Pablo Cirrone
{"title":"Design and validation of an integrated reference dosimetry and monitoring system for ultra-high dose-rate proton beams ranging from 20 Gy/s to 230 Gy/s","authors":"Giada Petringa,&nbsp;Roberto Catalano,&nbsp;Antonino Amato,&nbsp;Antonio Domenico Russo,&nbsp;Giuseppe Francesco Fustaino,&nbsp;Mariacristina Guarrera,&nbsp;Giacomo Cuttone,&nbsp;Gustavo Esteban Messina,&nbsp;Luigi Raffaele,&nbsp;Alfio Domenico Pappalardo,&nbsp;Giuseppe Antonio Pablo Cirrone","doi":"10.1016/j.ejmp.2025.105187","DOIUrl":"10.1016/j.ejmp.2025.105187","url":null,"abstract":"<div><h3>Purpose:</h3><div>This study aims to design, develop, and test an integrated reference dosimetry and beam monitoring system tailored for proton beams in a dose rate regime ranging from 20 Gy/s to 230 Gy/s. The primary objective is to establish a robust system for diagnostic and dosimetry addressing the challenges associated with ultra-high dose-rate (UHDR) radiotherapy. The proposed detectors chain seeks to ensure accurate dose measurements to support future clinical applications and radiobiological experiments in FLASH proton therapy (pFLASH-RT).</div></div><div><h3>Methods:</h3><div>The system integrates three detectors, a Secondary Emission Monitor (SEM), a Dual-Gap Ionization Chamber (DGIC), and a Faraday Cup (FC) , providing dose measurements. The SEM and DGIC operate continuously to monitor dose rates, while the FC, designed with innovative geometric and electronic features, ensures dose calibration. Experimental validations were conducted using a 62 MeV proton beam at the INFN-LNS, spanning various dose rates. Calibration procedures and correction algorithms, including the Boag–Wilson theory, were applied to ensure the reliability of the dosimetry and monitoring system.</div></div><div><h3>Results:</h3><div>Experimental results demonstrated high reproducibility and accuracy of the entire system. The FC exhibited a mean relative dose uncertainty of 2%, with no significant response variation across dose rates, even at the highest dose rate tested (230 Gy/s). Similarly, the SEM demonstrated consistent performance, with an average agreement within 1.4% of the FC measurements. Additionally, the application of correction factors based on collection efficiency parameters reduced the DGIC measurement uncertainty to less than 3%.</div></div><div><h3>Conclusion:</h3><div>The proposed system represents a reliable solution for the dosimetry of UHDR proton beams. Its ability to provide accurate, real-time dose measurements under extreme beam conditions supports the integration of pFLASH-RT into clinical practice. While the individual detectors employed in this work (Faraday Cup, DGIC, SEM) are based on established technologies, the innovation of this study lies in the integration and cross-calibration of these components within a single real-time dosimetric architecture, experimentally validated over a wide dose rate range. Furthermore, the system’s robustness and reproducibility make it an invaluable tool for advancing radiobiological research and ensuring the safe application of UHDR proton therapy.</div></div>","PeriodicalId":56092,"journal":{"name":"Physica Medica-European Journal of Medical Physics","volume":"138 ","pages":"Article 105187"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sound decisions: tuning into interuser variability and automation in ultrasound contrast resolution assessment 健全的决策:调整到用户间的可变性和自动化超声对比度分辨率评估
IF 2.7 3区 医学
Physica Medica-European Journal of Medical Physics Pub Date : 2025-10-01 DOI: 10.1016/j.ejmp.2025.105142
Deborah Jacob, Jess Fitzpatrick, Dara Ó’ Gallchobhair, Alan Stone
{"title":"Sound decisions: tuning into interuser variability and automation in ultrasound contrast resolution assessment","authors":"Deborah Jacob,&nbsp;Jess Fitzpatrick,&nbsp;Dara Ó’ Gallchobhair,&nbsp;Alan Stone","doi":"10.1016/j.ejmp.2025.105142","DOIUrl":"10.1016/j.ejmp.2025.105142","url":null,"abstract":"","PeriodicalId":56092,"journal":{"name":"Physica Medica-European Journal of Medical Physics","volume":"138 ","pages":"Article 105142"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145358017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Doses to members of public or staff who may encounter PET patients after a PET scan 在PET扫描后可能遇到PET患者的公众或工作人员的剂量
IF 2.7 3区 医学
Physica Medica-European Journal of Medical Physics Pub Date : 2025-10-01 DOI: 10.1016/j.ejmp.2025.105155
Colin Walsh, Geraldine O’ Reilly
{"title":"Doses to members of public or staff who may encounter PET patients after a PET scan","authors":"Colin Walsh,&nbsp;Geraldine O’ Reilly","doi":"10.1016/j.ejmp.2025.105155","DOIUrl":"10.1016/j.ejmp.2025.105155","url":null,"abstract":"","PeriodicalId":56092,"journal":{"name":"Physica Medica-European Journal of Medical Physics","volume":"138 ","pages":"Article 105155"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145358565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CT protocol optimisation for depth electrode visualisation 深度电极可视化的CT方案优化
IF 2.7 3区 医学
Physica Medica-European Journal of Medical Physics Pub Date : 2025-10-01 DOI: 10.1016/j.ejmp.2025.105109
Lauren Reilly , Michael O’Neill , Jessica Fitzpatrick
{"title":"CT protocol optimisation for depth electrode visualisation","authors":"Lauren Reilly ,&nbsp;Michael O’Neill ,&nbsp;Jessica Fitzpatrick","doi":"10.1016/j.ejmp.2025.105109","DOIUrl":"10.1016/j.ejmp.2025.105109","url":null,"abstract":"","PeriodicalId":56092,"journal":{"name":"Physica Medica-European Journal of Medical Physics","volume":"138 ","pages":"Article 105109"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145362375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FM Page 调频页面
IF 2.7 3区 医学
Physica Medica-European Journal of Medical Physics Pub Date : 2025-10-01 DOI: 10.1016/S1120-1797(25)00319-9
{"title":"FM Page","authors":"","doi":"10.1016/S1120-1797(25)00319-9","DOIUrl":"10.1016/S1120-1797(25)00319-9","url":null,"abstract":"","PeriodicalId":56092,"journal":{"name":"Physica Medica-European Journal of Medical Physics","volume":"138 ","pages":"Article 105209"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145362382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility study to investigate the introduction of HDR intraluminal brachytherapy 探讨引入HDR腔内近距离放疗的可行性研究
IF 2.7 3区 医学
Physica Medica-European Journal of Medical Physics Pub Date : 2025-10-01 DOI: 10.1016/j.ejmp.2025.105128
Sadhbh O’Toole , Anysja Zuchora , Cathal Coen
{"title":"Feasibility study to investigate the introduction of HDR intraluminal brachytherapy","authors":"Sadhbh O’Toole ,&nbsp;Anysja Zuchora ,&nbsp;Cathal Coen","doi":"10.1016/j.ejmp.2025.105128","DOIUrl":"10.1016/j.ejmp.2025.105128","url":null,"abstract":"","PeriodicalId":56092,"journal":{"name":"Physica Medica-European Journal of Medical Physics","volume":"138 ","pages":"Article 105128"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145362421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing shielding requirements for dental cone beam CT (CBCT) systems 评估牙科锥形束CT (CBCT)系统的屏蔽要求
IF 2.7 3区 医学
Physica Medica-European Journal of Medical Physics Pub Date : 2025-10-01 DOI: 10.1016/j.ejmp.2025.105154
Michael Rowan, Mandy Lewis
{"title":"Assessing shielding requirements for dental cone beam CT (CBCT) systems","authors":"Michael Rowan,&nbsp;Mandy Lewis","doi":"10.1016/j.ejmp.2025.105154","DOIUrl":"10.1016/j.ejmp.2025.105154","url":null,"abstract":"","PeriodicalId":56092,"journal":{"name":"Physica Medica-European Journal of Medical Physics","volume":"138 ","pages":"Article 105154"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145362963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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