Veterinaria Mexico最新文献

{"title":"Detection and whole genomic characterization of Bovine Papillomavirus type 1 associated with severe mammary cutaneous warts in Turkey","authors":"T. Oğuzoğlu, B. Koç, Z. Akkutay-Yoldar, S. Salar, A. Baştan","doi":"10.22201/fmvz.24486760e.2019.3.674","DOIUrl":"https://doi.org/10.22201/fmvz.24486760e.2019.3.674","url":null,"abstract":"Papilloma viruses (PVs) induce epithelial tumors in their natural hosts. These tumors are located on the mammary gland of cattle; therefore, PVs are considered viral agents with significant effects, both economical and on the animals’ health. Also, knowing the diversity of bovine PV (BPV) and its prevalence in countries worldwide is important to develop optimal diagnostic methods, as well as methods to fight this infection.The aim of the present study was to characterize the full-length genome of BPV 1 as the dominant type circulating among cattle in Turkey. It is the authors’ opinion that the results of this work provide useful information for further studies on the preventative steps that can be taken against BPV infection.","PeriodicalId":56044,"journal":{"name":"Veterinaria Mexico","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.22201/fmvz.24486760e.2019.3.674","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45062332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Canine lymphoma: Pathological and clinical characteristics of patients treated at a referral hospital","authors":"Diana Sánchez, Rogelio Sánchez-Verin, Hortensia Corona, Á. Gutiérrez, L. Núñez-Ochoa, Jesús Paredes, Gabriela Cesarman-Maus","doi":"10.22201/FMVZ.24486760E.2019.2.495","DOIUrl":"https://doi.org/10.22201/FMVZ.24486760E.2019.2.495","url":null,"abstract":"Non-Hodgkin’s lymphomas are common canine cancers with variable demographic and clinical presentations. Their pathological characterization and treatment lag far behind those of humans. We describe consecutive lymphoma patients detected over a one-year period at the National Autonomous University of Mexico (UNAM). Of 4,512 dogs: 220 (4.9%) had a cancer diagnosis, of which 27 (0.6%) had lymphoma (12% of cancer patients). We found an association with Miniature Schnauzers, which represented 18.5% (5/27) of lymphoma patients, but it was only 6.4% (288/4,512) of the dogs studied in this time period (p < 0.011). Miniature Schnauzers and mongrels together constituted nearly half of lymphoma cases. Mean age at diagnosis was 7.5 years (3-14), with a female to male ratio of 1.7:1. We found no correlation between lymphoma and castration status. Most patients presented nodal involvement (80%), were in advanced stages III/IV (90%) and had B-cell versus T-cell tumors (64%/36%). Only two histopathological patterns were seen, both with diffuse nodal-replacement by large immunoblast and/or centroblast-like cells; one having numerous tingible-body macrophages which are suggestive of a high proliferative rate. Chemotherapy was given to 15 patients (65%) with an overall response of 73% (3 complete responses/8 partial responses) and a mean overall survival of 219 days (4-586; SD±185). One cutaneous lymphoma-patient achieved partial response (PR) with lomustine/prednisone, and treatment was still ongoing at 548 days. Earlier diagnosis, better lymphoma subtype distinction, and specific curative treatments are needed.","PeriodicalId":56044,"journal":{"name":"Veterinaria Mexico","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.22201/FMVZ.24486760E.2019.2.495","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42135018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy-associated glycoproteins (PAGs) and progesterone concentrations in Holstein heifers following two methods of estrus syncronization","authors":"M. Akkose, C. Cebi Sen, A. Kirmit, O. Korkmaz, M. Yazlık, Murat Gocen, M. Kuru, E. Akçay","doi":"10.22201/FMVZ.24486760E.2019.2.646","DOIUrl":"https://doi.org/10.22201/FMVZ.24486760E.2019.2.646","url":null,"abstract":"Pregnancy-associated glycoproteins (PAGs) and progesterone concentrations were assessed in Holstein heifers 28 days post-insemination, following estrus synchronization with either a double prostaglandin (PG) injection or the ovsynch protocol. Animals between 15 and 20 months of age, with a 3-3.5 BCS, were randomly assigned to three groups: Heifers in the control group (n = 70) were monitored for estrus behaviour for 21 days and inseminated when detected in standing heat; Estrus of heifers in the Ovsynch group (n = 70)) was synchronized following the Ovsynch protocol, and timed artificial insemination was performed 16 h after the completion of treatment; Animals in the PG group (n = 70) received two prostaglandin-F2α injections 11 days apart, were monitored for estrus behaviour for 2-5 days following the last injection, and inseminated when in heat. Serum PAGs and progesterone concentrations were measured in pregnant heifers (control group n = 25; ovsynch group n = 22; PG group n = 21) on day 28 after artificial insemination (AI). Mean serum PAGs concentrations (OD: optical density) were similar between groups (control = 3.37 ± 0.148, Ovsynch = 3.21 ± 0.136, and PG = 3.34 ± 0.143; p > 0.05). However, serum progesterone concentrations were found to be lower in the ovsynch group (4.70 ± 0.17 ng/mL) when compared to the PG (5.34 ± 0.13 ng/mL) or the control (5.37 ± 0.08 ng/mL) groups (p < 0.001). There was no correlation between serum PAGs and progesterone levels at day 28 post-insemination, or between early pregnancy PAGs concentrations and fetal death rates. Further research, including multiple sampling time points throughout gestation, after estrus synchronization protocols is warranted, to determine if there are associated temporal changes in PAGs and progesterone profiles that could impact reproductive parameters in dairy heifers.","PeriodicalId":56044,"journal":{"name":"Veterinaria Mexico","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49634782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The rabbit as a surgical model for early training stages of the laparoscopic Nissen fundoplication technique","authors":"C. Rodríguez-Alarcón, Ramón Rivera-Barreno, H. Staines-Orozco, Rafael Cataño-Calatayud, J. Juárez, Jesús M Usón-Casaús, E. Pérez-Merino, Alfredo Hernandez-Perez, D. M. Beristain-Ruiz","doi":"10.22201/FMVZ.24486760E.2019.2.458","DOIUrl":"https://doi.org/10.22201/FMVZ.24486760E.2019.2.458","url":null,"abstract":"This study describes the advantages and disadvantages of using the rabbit as an animal model for surgical training in the Nissen laparoscopic fundoplication technique. Six New Zealand rabbits weighing between 2.5 and 3.5 kg were used. Nissen fundoplication was performed successfully in five out of six animals. Average procedure time was 47 minutes, with a maximum of 80 minutes for the first surgery and a minimum of 30 minutes for the last. Main advantages of the rabbit model are ease of animal restrain and low cost. The rabbit allows for the recreation of the human surgical environment, albeit showing a lower degree of difficulty. We thus consider this surgical model to be valuable only for skill development on basic stages of the laparoscopic Nissen fundoplication technique.  For advanced stages of this surgical procedure, use of other animal models with further anatomical similarities to humans, such as the swine model, are recommended.","PeriodicalId":56044,"journal":{"name":"Veterinaria Mexico","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.22201/FMVZ.24486760E.2019.2.458","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44250928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural Cysticercus fasciolaris infection in rodents from a rural area in Yucatan, Mexico","authors":"R. Medina-Pinto, M. Torres-Castro, Rolando A. Medina-Pinto, M. Bolio-Gonzalez, R. I. Rodríguez-Vivas","doi":"10.22201/FMVZ.24486760E.2019.2.590","DOIUrl":"https://doi.org/10.22201/FMVZ.24486760E.2019.2.590","url":null,"abstract":"Cysticercus fasciolaris is the larval stage of Taenia taeniaeformis, a parasite that predominantly affects felines. It, however, has zoonotic significance since humans can be accidental hosts. Rodents and lagomorphs act as Intermediate hosts in this parasite’s life cycle. The aim of this study was to determine the natural occurrence of infection with Cysticercus fasciolaris in rodents from a rural area in Yucatan, Mexico. Rodents were captured in 40 dwellings and two neighboring areas of low deciduous forest. A total of 153 individuals of seven different species were captured: 65 Rattus rattus (42.5%), 44 Mus musculus (28.8%), 22 Heteromys gaumeri (14.4%), 11 Ototylomys phyllotis (7.2%), 9 Peromyscus yucatanicus (5.9%), 1 Peromyscus leucopus (0.6%), and 1 Sigmodon hispidus (0.6%). All animals were examined for evidence of parasitic liver infection. Rattus rattus was the only species to present positive Cysticercus fasciolaris infection (18.5%, 12/65). We thus concluded that there was no evidence of a transmission cycle with wild rodent species.","PeriodicalId":56044,"journal":{"name":"Veterinaria Mexico","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.22201/FMVZ.24486760E.2019.2.590","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43245939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a single application of coumestrol and/or dimethyl sulfoxide, on sex hormone levels and vaginal cytology of anestrus bitches","authors":"S. Peña-Corona, Pablo León, E. Mendieta, Maximiliano Villanueva, Arturo Salame, D. Vargas, G. Mora, H. Serrano, A. Villa-Godoy","doi":"10.22201/FMVZ.24486760E.2019.1.656","DOIUrl":"https://doi.org/10.22201/FMVZ.24486760E.2019.1.656","url":null,"abstract":"Canine overpopulation continues to be a problem with serious public health implications, despite a diversity of programs and strategies that have been implemented for its control. Coumestrol (COU) is an organic compound with estrogenic activity, thus having the potential to alter reproduction in mammals. COU is commonly dissolved in dimethyl sulfoxide (DMSO) before administration; however, evidence indicates that DMSO is not inert. The aim of this study was to assess the effects of either a single oral administration of COU diluted in DMSO or of DMSO-alone, on serum progesterone (P4) and estradiol (E2), on vaginal cell pattern, and on anestrus and diestrus lengths in bitches. Fifteen anestrus female dogs received either a single commercial dog food biscuit (Control, n=5), a biscuit with 600 μg of COU/kg diluted in 20 μL of DMSO (COU, n=5), or a biscuit with 20 μL of DMSO (DMSO, n=5). Circulating P4, E2, and changes in vaginal cytology, were assessed within the first month after treatment administration. Hormone levels were also measured from months 2-6 post-treatment. Mean differences were analyzed by the GLM procedure for repeated measures. COU enhanced serum E2 levels, and DMSO increased serum P4, number of vaginal anucleated superficial cells, and diestrus length. All dogs were deemed healthy based on all periodical clinical exams, but abnormal mammary gland growth and/or galactorrhea were observed in two COU and one DMSO-treated bitches. The findings of the present study expose the need to reevaluate previous reports of use of COU in bitches, and perhaps in other mammals.Figure 1. Progesterone (A) and estradiol (B) serum levels in anoestrous bitches receiving a commercial dog food biscuit alone (Control; n=5), a biscuit with coumestrol diluted in dimethyl sulfoxide (COU; n=5), or a biscuit with only dimethyl sulfoxide (DMSO; n=5). a,b Different letters within sampling day indicate difference between treatments (P<0.05).*specifies statistical increase on post-treatment days 21 (P<0.0048) and 28 (0.0008). Data are presented as LSM ± standard error. ","PeriodicalId":56044,"journal":{"name":"Veterinaria Mexico","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.22201/FMVZ.24486760E.2019.1.656","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44759421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular identification of Toxoplasma gondii in roadkill wild animals in Yucatan, Mexico","authors":"M. Torres-Castro, R. Medina-Pinto, Henry Noh-Pech, F. Puerto, R. I. Rodríguez-Vivas","doi":"10.22201/FMVZ.24486760E.2019.1.511","DOIUrl":"https://doi.org/10.22201/FMVZ.24486760E.2019.1.511","url":null,"abstract":"Toxoplasma gondii is an obligate intracellular protozoan parasite, recognized as the etiologic agent of toxoplasmosis, a zoonotic endemic disease in several countries, including Mexico. In the Yucatan State of Mexico, Toxoplasma infection has a high impact in both human and domestic animal health. Wild animals can also host zoonotic pathogens such as Toxoplasma gondii. The presence of Toxoplasma gondii DNA in roadkill wild animals in Yucatan was detected using a nested Polymerase Chain Reaction. Toxoplasma gondii DNA was identified in several organs retrieved from a Yucatan squirrel (Sciurus yucatanensis), a coatimundi (Nasua narica), and a greater grison (Galictis vittata). The amplified fragments of Toxoplasma gondii DNA were purified, sequenced, and certified by BLAST analysis. Our results confirm that Toxoplasma gondii can infect wild mammals from Yucatan, which could act as intermediate hosts and contribute to the transmission of the disease to humans and domestic animals, as well as other wild animal species. We present the first molecular evidence of Toxoplasma gondii in a squirrel and a coatimundi from Yucatan, and quite possibly in a greater grison at a global level.Figure 1. Agarose gel presenting PCR amplicons (560 bp) positive to Toxoplasma gondii. 1) C+: positive control; A: Yucatan squirrel liver sample; B: great grison femoral muscle sample; C: coatimundi kidney sample; C-: negative control. 2) A: Yucatan squirrel brain sample; B: great grison lung sample; C-: negative control.","PeriodicalId":56044,"journal":{"name":"Veterinaria Mexico","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.22201/FMVZ.24486760E.2019.1.511","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45997573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of urolithiasis in dogs from Guadalajara City, Mexico","authors":"C. Mendoza-López, J. Del-Angel-Caraza, M. A. Aké-Chiñas, I. Quijano-Hernández, M. Barbosa-Mireles","doi":"10.22201/FMVZ.24486760E.2019.1.585","DOIUrl":"https://doi.org/10.22201/FMVZ.24486760E.2019.1.585","url":null,"abstract":"Urolithiasis is a frequent and recurrent problem in dogs around the world. Several epidemiological studies based on mineral composition of uroliths have been carried out in different geographical areas. The objective of this study was to analyze epidemiological data of 195 dogs with urolithiasis from the metropolitan area of Guadalajara Jalisco, Mexico. To determine the chemical composition of uroliths, quantitative and qualitative analyses were performed by means of stereoscopic microscopy and infrared spectroscopy. The dogs` median age was six years and a male-female ratio of 1.4:1 was observed. The most affected pure breed dogs were schnauzer, poodle, Labrador retriever, Yorkshire terrier, and German shepherd. The frequency of uroliths of struvite, calcium oxalate, urates, mixes, and compounds, is similar to the one found in other studies performed in other populations. However, a much higher frequency of silicate-containing uroliths (16.92%) was observed, both in a pure form as well as in mineral mixtures. These results led us to suggest the need to develop further investigations to determine the origin of this high frequency.Figure 1. Different types of uroliths. Note the differences in shape, size, color, and number; however, none of these characteristics is specific to a particular mineral composition.","PeriodicalId":56044,"journal":{"name":"Veterinaria Mexico","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.22201/FMVZ.24486760E.2019.1.585","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42185251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycobacterium tuberculosis and Mycobacterium bovis derived proteins induce caspase-independent apoptosis in bovine macrophages","authors":"Anaid Maciel Rivera, Susana Flores Villalva, Itzel Jiménez Vázquez, Omar Catalan Bárcenas, Clara Ines Espitia Pinzon, J. Morán, L. Arriaga-Pizano, Alejandro Benítez Guzmán, Edgar Alfonseca Silva, J. A. Gutiérrez-Pabello","doi":"10.22201/FMVZ.24486760E.2019.1.560","DOIUrl":"https://doi.org/10.22201/FMVZ.24486760E.2019.1.560","url":null,"abstract":"Species of the genus Mycobacterium are capable of inducing cell apoptosis. Infected cells with M. tuberculosis undergo apoptosis through a caspase-dependent pathway. We have previously shown that whole Mycobacterium bovis cells and derived crude protein extracts were able to trigger apoptosis through a caspase independent mechanism. However, the identity of the protein or protein fractions capable of inducing apoptosis has not been determined. In this study, bovine macrophages were incubated in the presence of Mycobacterium tuberculosis recombinant proteins and Mycobacterium bovis protein extracts to identify proteins capable of inducing apoptosis. A subgroup of proteins and protein extracts from strains of the Mycobacterium tuberculosis complex were shown to induce DNA fragmentation in bovine macrophages through a caspase independent pathway. Our findings suggest that bovine macrophages may elicit a different response to mycobacterium infection than that displayed by murine or human cells.","PeriodicalId":56044,"journal":{"name":"Veterinaria Mexico","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.22201/FMVZ.24486760E.2019.1.560","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47696440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Economic impact of pregnancy loss in an intensive dairy farming system","authors":"Christian Albuja, O. Ortíz, C. López, J. Cerón","doi":"10.22201/FMVZ.24486760E.2019.1.572","DOIUrl":"https://doi.org/10.22201/FMVZ.24486760E.2019.1.572","url":null,"abstract":"Occurrence of pregnancy loss and the related economic impact were determined in an intensively managed dairy herd. A total of 3,204 cow and heifer pregnancies were included over a two year period. Pregnancy loss was considered when: (1) cows or heifers that were diagnosed as pregnant by transrectal palpation, on days 50 to 50 postinsemination returned to estrus; (2) animals were found not to be pregnant at diagnosis confirmation on day 90, day 180, or during the drying-off period; and (3) if an abortion was clinically diagnosed. Data were analyzed through descriptive epidemiology and by survival analysis with the Kaplan-Meier method. The estimated cost of a single pregnancy loss was determined by the Monte Carlo methodology. Overall, 17.2% of cows (372/2,162) and 6.5% of heifers (68/1,042) had pregnany losses; the greater risk being in the first 90 days of gestation for cows (5.3/100 and 8.3/100 pregnancies in 2012 and 2013, respectively). Occurrence of pregnancy loss in heifers was also higher during the first trimester of gestation (1.7/100) in 2013. However, the pregnancy loss incidence peaked, between days 120 and 150 of gestation (1.7/100) in 2012. The cost of a single pregnancy loss during the first trimester was estimated at $5,253.00 (Mexican pesos), between days 91 and 180 at $9,674.00; and for over 181 days at $21,984.00. In conclusion, overall pregnancy loss rate in the studied herd was 17.2% for cows and 6.5% for heifers. The highest incidence of pregnancy loss occurred during the first 90 days of pregnancy. Thus, pregnancy loss may be the main reproductive cause affecting profitability of intensive dairy farming systems.","PeriodicalId":56044,"journal":{"name":"Veterinaria Mexico","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.22201/FMVZ.24486760E.2019.1.572","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44006210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}