Turkish Journal of Physical Medicine and Rehabilitation最新文献_第2页

Association of neuropathic pain with bladder and bowel dysfunction, functional disability, and quality of life of patients with multiple sclerosis. 神经性疼痛与多发性硬化症患者膀胱和肠功能障碍、功能障碍和生活质量的关系

IF 1.3 4区医学

Turkish Journal of Physical Medicine and Rehabilitation Pub Date : 2026-09-24 Epub Date: 2026-09-01 DOI: 10.4274/tftrd.2026.16463

Alper Mengi, Bengi Gül Türk, Melih Tütüncü, Sabahattin Saip, Aksel Siva, Uğur Uygunoğlu

{"title":"Association of neuropathic pain with bladder and bowel dysfunction, functional disability, and quality of life of patients with multiple sclerosis.","authors":"Alper Mengi, Bengi Gül Türk, Melih Tütüncü, Sabahattin Saip, Aksel Siva, Uğur Uygunoğlu","doi":"10.4274/tftrd.2026.16463","DOIUrl":"10.4274/tftrd.2026.16463","url":null,"abstract":"Objectives: To investigate the association between neuropathic pain (NP) and bladder/bowel dysfunction in multiple sclerosis (MS) and evaluate the association of NP with functional disability, quality of life, anxiety, depression, and sleep quality.Patients and methods: Patients diagnosed with MS based on the 2017 Revised McDonald criteria between who were between 18 and 65 years of age were included in our study. We analyzed data of 175 patients (56 male, 119 female). The patients were assessed for demographic and clinical characteristics, NP, bladder/bowel dysfunction, disability, health perception and quality of life, anxiety and depression, and sleep quality.Results: MS patients with NP had significantly higher Expanded Disability Status Scale (EDSS) scores, Hospital Anxiety and Depression Scale (HADS) for the subscales anxiety and depression, and Pittsburgh Sleep Quality Index (PSQI) scores (p<0.05). The patients with NP had a higher proportion of female patients and musculoskeletal pain (p<0.05). The patients with NP had significantly lower scores for Functional Independence Measure bladder and bowel scores; Monitoring My Multiple Sclerosis scale physical status, relationships, energy, and cognitive/mental and total scores. Sex, EDSS scores, HADS scores for anxiety subscale, and PSQI scores for subjective sleep quality subscale were independent predictors of NP (p=0.008, 0.002, 0.029, and 0.024, respectively; adjusted R2=0.438).Conclusion: Female sex, greater disability, higher anxiety levels, and poorer subjective sleep quality increase the likelihood of NP in MS. We found that bladder and bowel dysfunctions are more common among patients with NP; however, bladder or bowel dysfunction was not a predictor of NP.","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":" ","pages":"339-347"},"PeriodicalIF":1.3,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13618782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early mRNA expression of pro-inflammatory cytokines and ADAMTS-5 in an acute ischemia/reperfusion-induced pressure ulcer model, a pilot exploratory animal study. 促炎细胞因子和ADAMTS-5在急性缺血/再灌注性压疮模型中的早期mRNA表达，这是一项实验性动物研究。

IF 1.3 4区医学

Turkish Journal of Physical Medicine and Rehabilitation Pub Date : 2026-09-24 Epub Date: 2026-09-02 DOI: 10.4274/tftrd.2026.17484

Mustafa Sağlam, Burcu Yanık, Eralp Erdoğan, Zeynep Sıla Yaşar, Özlem Cemeroğlu, Betül Bakan, Haşim Çakırbay

{"title":"Early mRNA expression of pro-inflammatory cytokines and ADAMTS-5 in an acute ischemia/reperfusion-induced pressure ulcer model, a pilot exploratory animal study.","authors":"Mustafa Sağlam, Burcu Yanık, Eralp Erdoğan, Zeynep Sıla Yaşar, Özlem Cemeroğlu, Betül Bakan, Haşim Çakırbay","doi":"10.4274/tftrd.2026.17484","DOIUrl":"10.4274/tftrd.2026.17484","url":null,"abstract":"Objectives: This study aimed to determine the messenger ribonucleic acid (mRNA) expression levels of interleukin (IL)-1α, IL-1β, IL-6, IL-17, and A Disintegrin and Metalloproteinase with Thrombospondin Motifs (ADAMTS)-5 in an acute ischemia/reperfusion (I/R)-induced pressure ulcer (PU) model, in order to characterize the early inflammatory cytokine profile and explore the potential role of ADAMTS-5 in extracellular matrix (ECM) remodeling.Patients and methods: Ten BALB/c mice were randomly allocated to control and PU groups. Acute PUs were generated on the dorsal skin using a repeated I/R protocol achieved with ceramic magnetic plaques. Skin biopsies obtained from ulcerated and control areas were examined histologically using hematoxylin-eosin staining. mRNA expression levels of IL-1α, IL-1β, IL-6, IL-17, and ADAMTS-5 were analyzed by quantitative real-time PCR and compared statistically between groups.Results: Compared with controls, mRNA expression levels of IL-1α, IL-6, IL-17, and ADAMTS-5 were significantly increased in the PU group (p<0.05). In contrast, IL-1β expression showed an increase that did not reach statistical significance.Conclusion: These findings indicate that proinflammatory cytokines and ADAMTS-5 are activated early during PU formation following I/R injury. The observed upregulation of ADAMTS-5, a molecule that has been rarely examined in PU models, suggests a possible role for early ECM degradation in ulcer development. Further experimental and clinical studies are warranted to clarify the relevance of these pathways for PU progression and targeted local therapies.","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":" ","pages":"312-319"},"PeriodicalIF":1.3,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13618777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148876671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges in the application of Semmes-Weinstein monofilament testing: Practitioner-related variables Semmes-Weinstein单丝测试应用中的挑战：与从业者相关的变量。

IF 1.3 4区医学

Turkish Journal of Physical Medicine and Rehabilitation Pub Date : 2026-09-24 Epub Date: 2026-09-09 DOI: 10.4274/tftrd.2026.16607

İlkem Ceren Sığırtmaç, Özge Buket Arslan, Fatih Süleyman Okumuş, Abdullah Ruhi Soylu, Çiğdem Öksüz

{"title":"Challenges in the application of Semmes-Weinstein monofilament testing: Practitioner-related variables","authors":"İlkem Ceren Sığırtmaç, Özge Buket Arslan, Fatih Süleyman Okumuş, Abdullah Ruhi Soylu, Çiğdem Öksüz","doi":"10.4274/tftrd.2026.16607","DOIUrl":"10.4274/tftrd.2026.16607","url":null,"abstract":"Objectives: The Semmes-Weinstein monofilament (SWM) test is commonly used to evaluate tactile sensation in individuals with neurological or orthopedic conditions. This study aimed to examine practitioner-related factors affecting SWM testing, particularly focusing on adherence to protocol guidelines and the accuracy of force-controlled application, and to assess the intra-rater reliability of the measurements obtained.Patients and methods: Fifty-three inexperienced occupational therapists, trained in SWM application, participated in the study. Standardized tests were conducted using three monofilaments (4.31/2 g, 4.56/4 g, 5.07/10 g). A specialized instrument measurement system recorded maximum buckling forces (Max F), contact durations (T), and intervals between applications (L). Participants applied each filament perpendicularly to the sensor three times consecutively with 1.5-second intervals. Intrarater reliability was assessed using the intraclass correlation coefficient (ICC).Results: None of the participants achieved the exact prescribed buckling forces. Significant differences were observed between the prescribed buckling forces, application times, and intervals (p<0.05). However, each participant showed consistency across repeated trials (p>0.05). ICCs indicated good-to-excellent reliability for Max F, T, and L.Conclusion: Most errors in SWM testing were due to incorrect buckling force and failure to adhere to application timing. Future research should focus on improving practitioner training and minimizing variability in SWM test performance.","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":" ","pages":"375-383"},"PeriodicalIF":1.3,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13618768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148914559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physical activity and exercise in pediatric oncology: conceptual distinctions and clinical implications. 儿童肿瘤学的体育活动和锻炼：概念区别和临床意义。

IF 1.3 4区医学

Turkish Journal of Physical Medicine and Rehabilitation Pub Date : 2026-09-24 DOI: 10.4274/tftrd.2026.18471

Ayşe Resa Aydın, Yağmur Berktaş

{"title":"Physical activity and exercise in pediatric oncology: conceptual distinctions and clinical implications.","authors":"Ayşe Resa Aydın, Yağmur Berktaş","doi":"10.4274/tftrd.2026.18471","DOIUrl":"10.4274/tftrd.2026.18471","url":null,"abstract":"Survival in childhood cancers has markedly improved, yet many children experience treatment-related difficulties such as persistent fatigue, muscle weakness, reduced endurance, and impaired quality of life. As interest in non-pharmacological approaches grows, movement-based strategies, ranging from general physical activity to structured exercise, have become increasingly prominent in pediatric oncology care. This review aims to clarify the conceptual and practical differences between physical activity and structured exercise, and to summarize current evidence on movement-based interventions used during active treatment and survivorship in children and adolescents with cancer. Drawing on quantitative and qualitative studies published between 2000 and 2025, it shows that priorities shift across treatment phases: safety and feasibility are emphasized during active therapy, whereas long-term health and functional recovery gain importance in survivorship. The findings highlight the need for clearer terminology, coordinated multidisciplinary practice, meaningful family involvement, and consistent outcome measures with longer-term follow-up in future research.","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":"72 3","pages":"275-282"},"PeriodicalIF":1.3,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13617965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149032062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mirror movement disorder rehabilitation after epilepsy: A case report and video presentation. 癫痫后镜像运动障碍的康复：1例报告及视频报告。

IF 1.3 4区医学

Turkish Journal of Physical Medicine and Rehabilitation Pub Date : 2026-09-24 Epub Date: 2025-12-19 DOI: 10.5606/tftrd.2026.16429

Aslı Keles Önal, Ali Yavuz Karahan, Seda Evyapan Aydın

引用次数: 0

Effectiveness of vestibular electrical stimulation combined with vestibular rehabilitation in chronic unilateral vestibular hypofunction: A randomized controlled trial. 前庭电刺激联合前庭康复治疗慢性单侧前庭功能减退的有效性：一项随机对照试验。

IF 1.3 4区医学

Turkish Journal of Physical Medicine and Rehabilitation Pub Date : 2026-09-24 DOI: 10.4274/tftrd.2026.17374

Bilal Burak Bayraklı, Canan Çelik, Ömer Kuzu, Özlem Öztürk Tan

{"title":"Effectiveness of vestibular electrical stimulation combined with vestibular rehabilitation in chronic unilateral vestibular hypofunction: A randomized controlled trial.","authors":"Bilal Burak Bayraklı, Canan Çelik, Ömer Kuzu, Özlem Öztürk Tan","doi":"10.4274/tftrd.2026.17374","DOIUrl":"10.4274/tftrd.2026.17374","url":null,"abstract":"Objectives: To evaluate the effectiveness of vestibular electrical stimulation (VES) combined with vestibular rehabilitation (VR) in patients with chronic unilateral vestibular hypofunction (UVH).Patients and methods: Forty patients aged 18-65 years, diagnosed with UVH, were randomized into two groups. Participants underwent a 4-week intervention: the VR group received supervised VR, whereas the VR+VES group received VES in addition to supervised VR. The groups were evaluated before and after treatment, including the dizziness handicap inventory (DHI), visual analogue scale (VAS), Berg balance scale (BBS), timed up-and-go test (TUG), activity-specific balance and confidence scale (ABCs), Beck anxiety inventory (BAI), Beck depression inventory (BDI), and static posturography.Results: Thirty-eight of 40 enrolled patients (95%) completed the study. Statistically significant improvements were observed in DHI, VAS, BBS, and ABCs scores in both groups after treatment (p<0.05). Additionally, the VR+VES group showed significant improvements in TUG, BAI, BDI, and right-sided limits of stability (p<0.05).Conclusion: Supervised VR effectively improved dizziness severity, balance, and functional status in patients with chronic UVH. The addition of VES to supervised VR further enhanced postural stability, reduced the risk of falls, and alleviated symptoms of anxiety and depression.","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":"72 3","pages":"384-392"},"PeriodicalIF":1.3,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13618785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149032144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychometric validation of the Turkish version of the Neuropathic Pain Symptom Inventory. 土耳其版神经性疼痛症状量表的心理测量验证。

IF 1.3 4区医学

Turkish Journal of Physical Medicine and Rehabilitation Pub Date : 2026-09-24 Epub Date: 2026-09-02 DOI: 10.4274/tftrd.2026.17272

Serpil Savaş, Ayşegül Garip Honamlıoğlu, Adnan Karaibrahimoğlu, Serpil Demirci

{"title":"Psychometric validation of the Turkish version of the Neuropathic Pain Symptom Inventory.","authors":"Serpil Savaş, Ayşegül Garip Honamlıoğlu, Adnan Karaibrahimoğlu, Serpil Demirci","doi":"10.4274/tftrd.2026.17272","DOIUrl":"10.4274/tftrd.2026.17272","url":null,"abstract":"Objectives: Certain symptoms of neuropathic pain and their combinations respond differently to various treatments. The Neuropathic Pain Symptom Inventory (NPSI) performs sensory phenotyping, providing a detailed assessment of neuropathic pain qualities, demonstrating responsiveness to changes in pain, and classifying patients for clinical trials in both central and peripheral conditions. This study aimed to perform a psychometric validation of the Turkish version of the NPSI (NPSI-T).Patients and methods: In this cross-sectional study, the NPSI-T, Douleur Neuropathique 4, and Numeric Rating Scale were administered twice to 275 patients with central and peripheral neuropathic pain (PNP) at 1-week intervals. All reliability and validity analyses, including factor analyses, Cronbach's alpha, Hotelling's T2, Tukey's test of nonadditivity, and item analysis, were performed using SPSS 27.0 (IBM Corp., Armonk, NY, USA). Software to compute descriptive statistics.Results: The NPSI-T showed high reliability with a Cronbach's alpha of 0.89, an internal consistency Spearman-Brown coefficient of 0.779, and a significant 27% difference between upper and lower groups. The total explained variance was 61.58%, and five subdimensions were identified through exploratory factor analysis. Confirmatory factor analysis confirmed that the structure, consisting of four subdimensions with 9 items, is valid, as indicated by excellent goodness-of-fit indices.Conclusion: The results of this study indicate that the NPSI-T is a reliable and valid instrument for assessing Turkish patients with central and PNP syndromes.","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":" ","pages":"329-338"},"PeriodicalIF":1.3,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13618776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148876754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurourological chaos in the first year after spinal cord injury. 脊髓损伤后第一年的神经紊乱。

IF 1.3 4区医学

Turkish Journal of Physical Medicine and Rehabilitation Pub Date : 2026-09-24 Epub Date: 2026-08-06 DOI: 10.4274/tftrd.2026.18249

Necmettin Yıldız

引用次数: 0

An unexpected catastrophe: Femoral neck fracture two hours after epidural steroid injection. 意外的灾难：硬膜外类固醇注射两小时后股骨颈骨折。

IF 1.3 4区医学

Turkish Journal of Physical Medicine and Rehabilitation Pub Date : 2026-09-04 DOI: 10.4274/tftrd.2026.17690

Günay Er, Rekib Saçaklıdır, Tuğçe Güven Ekiz, Tülay Şahin