Luiza Ferreira Moreira, Vanessa Knust Coelho, Lucas Ferreira Mendonça, Felipe J J Reis, Gustavo Felicio Telles, Leandro Alberto Calazans Nogueira
{"title":"Pain intensity and lower limb dynamic balance were related to the laterality judgment test of patients with patellofemoral pain.","authors":"Luiza Ferreira Moreira, Vanessa Knust Coelho, Lucas Ferreira Mendonça, Felipe J J Reis, Gustavo Felicio Telles, Leandro Alberto Calazans Nogueira","doi":"10.1016/j.msksp.2025.103259","DOIUrl":"https://doi.org/10.1016/j.msksp.2025.103259","url":null,"abstract":"<p><strong>Introduction: </strong>Laterality judgement evaluates the capacity to differentiate between the left and right sides of bodily parts. Cortical body representations are impaired in various musculoskeletal conditions, yet this remains unexplored in individuals with patellofemoral pain (PFP).</p><p><strong>Objective: </strong>This study compared laterality judgement performance between individuals with PFP and asymptomatic controls. Additionally, we investigated the relationship between laterality judgement and self-reported disability, physical performance, and dynamic stability within the PFP group.</p><p><strong>Methods: </strong>A secondary analysis encompassed 48 patients and 48 controls. Participants were examined for laterality judgement, pain intensity, knee disability, physical performance and lower limb dynamic balance. Statistical analyses included Student's t-test for group differences and linear regression to examine relationships between laterality judgement and other measurements.</p><p><strong>Results: </strong>The sample comprised 60 males (62.5%) with a mean age of 31.3 years. The PFP group reported a mean pain duration of 37.6 months and moderate pain intensity (4/10). Laterality judgement accuracy and time were identical between the PFP group (78.3% and 2.1 s, respectively) and controls (80.8% and 2.2 s, respectively) (accuracy p = 0.50 and time p = 0.66). Lower limb dynamic and pain intensity were related to laterality judgement accuracy (β = 0.4, p < 0.01) and time (β = 0.4, p = 0.03), respectively.</p><p><strong>Conclusion: </strong>PFP and control groups demonstrated similar laterality judgement performance. In the PFP group, lower laterality judgement accuracy was related to dynamic balance and lower laterality judgement time was related to pain intensity. The physical performance and self-reported knee disability were not related to the knee laterality judgment of these patients.</p>","PeriodicalId":56036,"journal":{"name":"Musculoskeletal Science and Practice","volume":"76 ","pages":"103259"},"PeriodicalIF":2.2,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabelle Allworth, Georgina Luscombe, Paulo Ferreira, Carlos Mesa-Castrillon
{"title":"Exploring participant satisfaction with an eHealth intervention for low back pain and knee osteoarthritis: Enhancing physiotherapy access in rural Australia.","authors":"Isabelle Allworth, Georgina Luscombe, Paulo Ferreira, Carlos Mesa-Castrillon","doi":"10.1016/j.msksp.2024.103252","DOIUrl":"https://doi.org/10.1016/j.msksp.2024.103252","url":null,"abstract":"<p><strong>Introduction: </strong>Accessing health services in rural Australia is challenging and innovative solutions to meet residents' needs are required. Research into eHealth is crucial as it offers potential solutions to these challenges. The study aimed to assess participants' satisfaction and experience with an eHealth physiotherapy intervention at improving physical function for low back pain and knee osteoarthritis in rural Australia.</p><p><strong>Methods: </strong>Telephone surveys collected data on participant satisfaction and experiences. Satisfaction was rated on a scale of 0-10, and the data was presented descriptively and compared between groups (eHealth and usual care) using Mann-Whitney U tests. Participant experiences with the pilot trial were gathered using open-ended questions, categorised and presented descriptively.</p><p><strong>Results: </strong>75/156 (48%) participants responded to the satisfaction survey. Overall satisfaction was significantly higher for the eHealth group, median = 9 [IQR: 8-10] compared with the usual care group, median = 8 [IQR: 5-9] (p = 0.025). Satisfaction was also significantly higher in the eHealth group for all secondary measures in the study, including accessibility to healthcare practitioner (p = 0.001), time to contact physiotherapist (p = 0.011), cost of intervention (p < 0.001) and distance travelled (p < 0.001). For the pilot experiences, inconvenient aspects such as completing forms/administration and travel were significantly higher in the usual care group, while difficulties with exercises, were significantly higher in the eHealth group (p = 0.005).</p><p><strong>Conclusions: </strong>An eHealth intervention for physiotherapy is acceptable to patients with knee osteoarthritis and low back pain in rural Australia. Future telehealth interventions should pay special attention to participant's exercise workload and motivation.</p>","PeriodicalId":56036,"journal":{"name":"Musculoskeletal Science and Practice","volume":"76 ","pages":"103252"},"PeriodicalIF":2.2,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samantha Charmaine Bengtsen, Joshua Robert Zadro, Michael Skovdal Rathleff, Nadine E Foster, Janus Laust Thomsen, Jens Lykkegaard Olesen, Jens Søndergaard, Kristian Damgaard Lyng
{"title":"Exploring the decisional needs of patients living with subacromial pain syndrome: A qualitative needs assessment study.","authors":"Samantha Charmaine Bengtsen, Joshua Robert Zadro, Michael Skovdal Rathleff, Nadine E Foster, Janus Laust Thomsen, Jens Lykkegaard Olesen, Jens Søndergaard, Kristian Damgaard Lyng","doi":"10.1016/j.msksp.2025.103255","DOIUrl":"https://doi.org/10.1016/j.msksp.2025.103255","url":null,"abstract":"<p><strong>Background: </strong>There are a variety of different treatments for patients living with subacromial pain syndrome (SAPS). All treatments have small to moderate effect sizes, and it is challenging when healthcare practitioners and patients need to decide on which treatment options to choose. The aim of this study was to explore and understand the decisional needs of patients with SAPS, to inform and support the decision-making process.</p><p><strong>Methods: </strong>A qualitative research study, using semi-structured individual interviews with patients with SAPS. The interview guide was informed by the Ottawa Decision Support Framework (ODSF), previous research related to treatment decision-making, other decisional needs assessment studies, and inputs from patients with SAPS and healthcare practitioners. Data were analysed by using reflexive thematic text analysis and ODSF. The analysis was conducted in NVivo 12.</p><p><strong>Results: </strong>We invited 22 participants of which 17 (age 22-71 years) took part in the study. We found three main themes related to individual decisional needs in the context of decision-making: 1) The necessity of certainty and adequate information as fundamental prerequisites for effective decision-making, 2) The importance of person-centered care to achieve a desirable decision, and 3) The need for a supportive environment to facilitate adaptation and acceptance of the decision.</p><p><strong>Conclusion: </strong>The decision-making process faced by patients with SAPS is complex and involves several decisional needs. Our findings highlight the importance of healthcare professionals identifying and addressing patients' decisional needs in consultations with patients with SAPS.</p>","PeriodicalId":56036,"journal":{"name":"Musculoskeletal Science and Practice","volume":"76 ","pages":"103255"},"PeriodicalIF":2.2,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alison Grimaldi, Charlotte Ganderton, Anthony Nasser
{"title":"Gluteal tendinopathy masterclass: Refuting the myths and engaging with the evidence.","authors":"Alison Grimaldi, Charlotte Ganderton, Anthony Nasser","doi":"10.1016/j.msksp.2025.103253","DOIUrl":"https://doi.org/10.1016/j.msksp.2025.103253","url":null,"abstract":"<p><strong>Introduction: </strong>Gluteal tendinopathy is a prevalent and impactful condition. For many decades clinical practice has been guided by 'myths' that developed around clinical beliefs. It's time to examine these myths and engage with the substantial evidence base.</p><p><strong>Purpose: </strong>This masterclass aims to: (i) engage with the evidence to refute the most common myths associated with gluteal tendinopathy and trochanteric pain, and (ii) provide clinicians with guidance around contemporary, evidence-based clinical practice.</p><p><strong>Implications: </strong>It is time to put aside traditional beliefs that focused on anti-inflammatory treatments, including rest and corticosteroid injections as first line management for trochanteric pain. Contemporary management of tendinopathy takes an active approach that empowers the individual to manage their own condition through education, load management, progressive exercise and optimisation of their general health. The body of evidence for gluteal tendinopathy supports health professionals in employing such principles with greater confidence.</p>","PeriodicalId":56036,"journal":{"name":"Musculoskeletal Science and Practice","volume":"76 ","pages":"103253"},"PeriodicalIF":2.2,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143043455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laryssa Oliveira Silva, Amanda Paula Ricardo Rodrigues da Cunha, Jefferson Rosa Cardoso, Christiane de Souza Guerino Macedo
{"title":"Performance, measurement properties and discriminant analysis of functional tests for women with greater trochanter pain syndrome.","authors":"Laryssa Oliveira Silva, Amanda Paula Ricardo Rodrigues da Cunha, Jefferson Rosa Cardoso, Christiane de Souza Guerino Macedo","doi":"10.1016/j.msksp.2025.103256","DOIUrl":"https://doi.org/10.1016/j.msksp.2025.103256","url":null,"abstract":"<p><strong>Introduction: </strong>Functional tests are used to establish the functional capacity of women with Greater Trochanteric Pain Syndrome (GTPS). However, the validity, reliability, or possibility of discriminating this dysfunction have not been established.</p><p><strong>Objectives: </strong>To compare functional capacity, establish the properties of functional test measurements, and present the best test to discriminate between women with and without GTPS.</p><p><strong>Methods: </strong>A total of 46 women were evaluated (23 with GTPS/23 asymptomatic). On the first day, two evaluators analyzed the muscle strength of the quadriceps and lateral hip complex and performance in the 30-s sit to stand test (STS30), stair ascent test (SAT), stair descent test (SDT), and Timed Up and Go test (TUG). On the second day, evaluator 1 repeated the assessment. The results were established by the intraclass correlation coefficient, Spearman's correlation test, and discriminant analysis.</p><p><strong>Results: </strong>The GTPS group showed worse results in the VISA-G (P < 0.001), SAT (P = 0.009), SDT (P = 0.033), and TUG (P = 0.039). Intra-evaluator reliability ranged from moderate to excellent and inter-examiner reliability from good to excellent in this sample. Validity could not be established. Only SAT and TUG tests differentiated the participants with GDTS from the asymptomatic group.</p><p><strong>Conclusion: </strong>Women with GTPS present worse functional capacity compared to asymptomatic women. The functional tests used were reliable, but not valid. The SAT and TUG, when used for functional performance diagnosis, were able to discriminate between individuals with GTPS and asymptomatic group over 40 years of age.</p>","PeriodicalId":56036,"journal":{"name":"Musculoskeletal Science and Practice","volume":"76 ","pages":"103256"},"PeriodicalIF":2.2,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor regarding \"Anaesthetic and corticosteroid response immediately following epidural injection in patients with MRI confirmed lumbar disc herniation\".","authors":"Alper Mengi","doi":"10.1016/j.msksp.2025.103254","DOIUrl":"https://doi.org/10.1016/j.msksp.2025.103254","url":null,"abstract":"","PeriodicalId":56036,"journal":{"name":"Musculoskeletal Science and Practice","volume":"76 ","pages":"103254"},"PeriodicalIF":2.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chalomjai Pensri, Zhiqi Liang, Julia Treleaven, Gwendolen Jull, Lucy Thomas
{"title":"Cervical musculoskeletal impairments in migraine and tension-type headache and relationship to pain related factors: An updated systematic review and meta-analysis.","authors":"Chalomjai Pensri, Zhiqi Liang, Julia Treleaven, Gwendolen Jull, Lucy Thomas","doi":"10.1016/j.msksp.2024.103251","DOIUrl":"https://doi.org/10.1016/j.msksp.2024.103251","url":null,"abstract":"<p><strong>Background: </strong>An updated systematic review of cervical musculoskeletal dysfunction in migraine and tension-type headache is needed. Influencing factors (pain hypersensitivity with cervical musculoskeletal testing, active trigger points and tenderness) have not been investigated.</p><p><strong>Objectives: </strong>To i) update evidence for cervical musculoskeletal impairments in migraine and tension-type headache ii) report on accompanying pain associated with testing, active trigger points and tenderness in headache; iii) determine relationships between these sensitivity features and cervical musculoskeletal impairments in headache.</p><p><strong>Methods: </strong>Five databases were searched for observational studies. Quality of studies was assessed with JBI Critical Appraisal. Meta-analysis was performed using random effect models. Certainty of the evidence was assessed using GRADE.</p><p><strong>Results: </strong>Seventy-seven studies were included comprising 2551 participants. New findings in migraine were increased forward head posture in standing (MD = -2.51°[-4.94°, -0.09°]), reduced flexion/rotation range (MD = -9.47°[-15.78°, -3.16°]), reduced flexor strength (Std. MD = -0.34[-0.57, -0.10]) and endurance (MD = -14.37[-28.15, -0.58]), and reduced extensor strength (Std. MD = -0.34[-0.60, -0.08]) in migraine. Tension-type headache had reduced extensor strength (Std. MD = -0.45[-0.85, -0.04]). Certainty was very low for all findings due to heterogeneity and small effect size. Active trigger points and tenderness were common, particularly, in chronic headache. A negative relationship between cervical musculoskeletal performance and active trigger points and tenderness was found in 2 from 77 studies (r < - 0.47).</p><p><strong>Conclusions: </strong>Several cervical musculoskeletal impairments are present in migraine and tension-type headache with very low certainty. Caution is needed since few studies considered factors that would influence testing.</p>","PeriodicalId":56036,"journal":{"name":"Musculoskeletal Science and Practice","volume":"76 ","pages":"103251"},"PeriodicalIF":2.2,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Chys, K. De Meulemeester, M. De Sloovere, I. De Greef, V. Dewitte, B. Cagnie
{"title":"Evaluating the effectiveness of patient-tailored treatment for patients with non-specific (sub)acute neck pain","authors":"M. Chys, K. De Meulemeester, M. De Sloovere, I. De Greef, V. Dewitte, B. Cagnie","doi":"10.1016/j.msksp.2024.103235","DOIUrl":"10.1016/j.msksp.2024.103235","url":null,"abstract":"<div><h3>Background</h3><div>An important issue in the debate about best practice management of non-specific neck pain (NSNP) is the effectiveness of tailored versus generalized interventions.</div></div><div><h3>Methods</h3><div>Participants with (sub)acute NSNP were randomly allocated to a patient-tailored treatment (PTT), non-patient-tailored treatment (NPTT) or control group (no intervention). The outcome measures were pain (NPRS), disability (NDI), global perceived effect and satisfaction (GPES), productivity costs, and medical consumption. Patients were assessed at baseline, post-intervention, and at 3-, 6-, and 12-months post-intervention. Evolution of the complaints, treatment adherence, and medication intake was registered during the intervention period. Linear mixed models were used to examine interaction effects as well as between- and within-group differences.</div></div><div><h3>Results</h3><div>Sixty-one participants were included. There was no “Group x Time”-interaction effect for all outcome measures. Nevertheless, all groups showed significant and clinically relevant within-group differences at all time points for pain and disability (p < 0.001). At 6 months follow-up, NPTT was superior to PTT for reductions in pain but not for disability. At 1 year, the number of responders in the NPTT group remained higher (75%) compared to the PTT group (40%).</div></div><div><h3>Conclusion</h3><div>This study found a significant and clinically relevant reduction of pain and disability within all groups. Patient-tailored treatment as well as NPTT can be considered an effective method when aiming for a reduction in pain and disability at short-term (12 weeks). However, NPTT seemed to be more effective at 1-year follow-up and therapists should consider spontaneous recovery. The results should be interpreted with caution and further research is warranted.</div></div>","PeriodicalId":56036,"journal":{"name":"Musculoskeletal Science and Practice","volume":"75 ","pages":"Article 103235"},"PeriodicalIF":2.2,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A seventeen-year, population-based study to identify dynamic patterns of interfering neck pain and its burden in South Korea","authors":"Miran Goo , Deokhoon Jun","doi":"10.1016/j.msksp.2024.103236","DOIUrl":"10.1016/j.msksp.2024.103236","url":null,"abstract":"<div><h3>Aim</h3><div>The aim of this study were to introduce a profile of a nationwide cohort for patients with neck pain and to identify the patterns of recurrent neck pain over time.</div></div><div><h3>Methods</h3><div>Health insurance data for 1,127,323 patients (43.5 ± 11.5 years, 60.8% females) with neck pain in 2010 were extracted from the National Health Information Database of South Korea. Data on the duration and frequency of neck pain and the number of healthcare visits recorded between 2002 and 2018 were screened and used for descriptive analysis.</div></div><div><h3>Results</h3><div>During the study period, patients experienced 4.1 episodes of neck pain, and 74% of patients experienced multiple episodes. The duration of one episode was 12.1 ± 35.7 days. Following each episode, more than 73% of patients experienced a subsequent episode of neck pain. As patients experienced more episodes, the recurrence rate increased gradually from 73% to 80%, and subsequent episodes occurred in a shorter time and lasted longer with a higher number of healthcare visits, compared to a preceding episode.</div></div><div><h3>Conclusion</h3><div>The study highlighted the dynamic pattern of interfering neck pain, with episodes occurring more frequently and lasting longer over time. Early intensive management with a long-term follow-up is recommended to prevent a dynamic pattern of interfering neck pain.</div></div>","PeriodicalId":56036,"journal":{"name":"Musculoskeletal Science and Practice","volume":"75 ","pages":"Article 103236"},"PeriodicalIF":2.2,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142723894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Machine learning for classifying chronic ankle instability based on ankle strength, range of motion, postural control and anatomical deformities in delivery service workers with a history of lateral ankle sprains","authors":"Ui-jae Hwang , Oh-yun Kwon , Jun-hee Kim , Gyeong-tae Gwak","doi":"10.1016/j.msksp.2024.103230","DOIUrl":"10.1016/j.msksp.2024.103230","url":null,"abstract":"<div><h3>Objective</h3><div>Chronic ankle instability (CAI) frequently develops as a result of lateral ankle sprains (LAS) in delivery service workers (DSWs). Identifying risk factors for CAI is crucial for implementing targeted interventions. This study aimed to develop machine learning (ML) models for classifying CAI in DSWs with a history of LAS (DSWsLAS) and to identify key contributory factors.</div></div><div><h3>Design</h3><div>Exploratory, cross-sectional design.</div></div><div><h3>Setting</h3><div>and participants: A total of 121 DSWsLAS were screened for eligibility among 289 DSWs.</div></div><div><h3>Methods</h3><div>A total of 121 DSWsLAS were assessed for demographic characteristics, including ankle strength, range of motion, postural control, and anatomical deformities. Seven ML algorithms were trained and tested for classifying CAI. Principal component analysis (PCA) was used for feature extraction, and feature permutation importance (FPI) and Shapley additive explanations (SHAP) were employed to identify influential features.</div></div><div><h3>Main outcome measures</h3><div>Model performances were assessed using area under the curve (AUC). To interpret the classifications, we used FPI and SHAP values.</div></div><div><h3>Results</h3><div>PCA derived 7 principal components (PCs) accounting for 83.5% of the total variation in the data. The support vector machine (SVM) algorithm achieved the highest classifying performance (AUC = 0.817) among the ML models. FPI and SHAP revealed that PC1, PC2, PC5, and PC7 were the most influential features for classifying CAI in DSWsLAS.</div></div><div><h3>Conclusions</h3><div>The SVM algorithm, utilizing PCA-derived factors related to body mass index and ankle muscle strength demonstrated high classifying performance for diagnosis of CAI in DSWsLAS, emphasizing the importance of considering multiple contributory factors in the prevention and management of this condition.</div></div>","PeriodicalId":56036,"journal":{"name":"Musculoskeletal Science and Practice","volume":"75 ","pages":"Article 103230"},"PeriodicalIF":2.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142696248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}