AsianPacific Island Nursing Journal最新文献

{"title":"Effectiveness of Interventions to Improve Glycemic Control in US Asian and Pacific Islander Populations With Type 2 Diabetes: Systematic Review and Meta-Analysis.","authors":"Jason Xiao, Jielu Yu, Erin M Staab, Nikita C Thomas, Wen Wan, Amber N Deckard, Andrew J Karter, Monica E Peek, Elbert S Huang, Neda Laiteerapong","doi":"10.2196/75751","DOIUrl":"10.2196/75751","url":null,"abstract":"<p><strong>Background: </strong>Asian American and Pacific Islander populations are disproportionately affected by diabetes.</p><p><strong>Objective: </strong>The purpose of this study was to assess the efficacy of nonpharmacologic interventions in reducing hemoglobin A1c (HbA1c) levels among Asian American or Pacific Islander individuals with type 2 diabetes.</p><p><strong>Methods: </strong>A systematic review was conducted using the PubMed, Scopus, PsycInfo, and CINAHL databases, covering studies published from 1985 to 2019. Eligible studies were randomized controlled trials that evaluated nonpharmacologic interventions in outpatient settings for adults with type 2 diabetes in the United States, with at least 50% Asian American or Pacific Islander participants. Data extraction and risk of bias assessment were independently performed by 2 reviewers for each trial. The Cochrane Collaboration risk of bias tool and the Grading of Recommendations, Assessment, Development, and Evaluation approach were used to evaluate quality. Random-effects meta-analyses were conducted to estimate pooled effect sizes.</p><p><strong>Results: </strong>A total of 1835 articles were screened, with 9 randomized controlled trials meeting the inclusion criteria, comprising 1492 participants, with a median follow-up duration of 6 (IQR 3-12) months. Interventions included diabetes self-management education, bilingual counseling, glucose or weight monitoring, motivational interviewing, and financial support, often tailored to the cultural context of the participants. Pooled analysis of the 9 trials demonstrated a significant average HbA1c reduction of -0.39% (95% CI -0.64% to -0.14%; I²=65%). Seven studies were judged to have a low risk of bias, 1 study had some concerns, and 1 study was assessed as high risk. The overall strength of evidence was high.</p><p><strong>Conclusions: </strong>Nonpharmacologic interventions substantively reduced HbA1c levels in Asian American or Pacific Islander individuals with type 2 diabetes, particularly when culturally and linguistically tailored.</p>","PeriodicalId":55723,"journal":{"name":"AsianPacific Island Nursing Journal","volume":"10 ","pages":"e75751"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13132533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147823830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Online Media Platform and Continuous Positive Airway Pressure Machine Purchasing Prior to Bariatric Surgery: Qualitative Study.","authors":"Bundit Sawunyavisuth, Darunee Jongudomkarn, Kittisak Sawanyawisuth","doi":"10.2196/84098","DOIUrl":"10.2196/84098","url":null,"abstract":"<p><strong>Background: </strong>Bariatric surgery offers quick weight reduction for patients with morbid obesity. Those who plan for bariatric surgery require perioperative preparation, including obstructive sleep apnea (OSA) evaluation, and treatment using a continuous positive airway pressure (CPAP) machine is recommended. There are limited data on how patients have prepared for bariatric surgery or for those who have decided to purchase a CPAP machine prior to surgery.</p><p><strong>Objective: </strong>This study aimed to use a qualitative method to evaluate how obese patients with OSA who were scheduled for bariatric surgery received information regarding bariatric surgery, including their decision to purchase a CPAP machine prior to bariatric surgery.</p><p><strong>Methods: </strong>This qualitative study enrolled adult patients who planned to undergo bariatric surgery, were diagnosed with OSA, and were treated with CPAP therapy at least 1 month prior to surgery. An in-depth interview was conducted with eligible patients, addressing their perspectives on obesity, strategies for weight loss, and reasons for purchasing or renting CPAP machines prior to bariatric surgery. The interview was conducted using content analysis and triangulation focused on a variety of data informants, theoretical sampling, and achieving data saturation. Themes were summarized and reported.</p><p><strong>Results: </strong>There were 14 patients with obesity and OSA who planned for bariatric surgery. The average age of all patients was 27.21 (SD 4.98) years with male proportion of 28.57% (4/14) and single marital status of 78.57% (11/14). The average BMI was 45.28 (SD 7.58) kg/m2 and the average apnea-hypopnea index was 40.42 (SD 29.61) events per hour. Seven themes were reported: the causes of obesity, effects of obesity, effects of weight loss, experiences of social media on weight loss, CPAP therapy prior to bariatric surgery, and experiences of social media on bariatric surgery. Morbidly obese patients with OSA who planned for bariatric surgery experienced physical and mental effects of obesity, including social stigmatization. These patients had failed in various weight loss programs and believed that bariatric surgery was the correct solution. Social media was used for data gathering in terms of bariatric surgery and CPAP therapy. CPAP rental or secondhand purchasing was preferred.</p><p><strong>Conclusions: </strong>Social media platforms are a source of information prior to bariatric surgery. A CPAP machine is not a lifesaving machine; rather, it is a temporary treatment before surgery and may not be required after weight loss. CPAP rental or secondhand purchasing may be preferred. These are participant beliefs, not clinical conclusions.</p>","PeriodicalId":55723,"journal":{"name":"AsianPacific Island Nursing Journal","volume":"10 ","pages":"e84098"},"PeriodicalIF":0.0,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a Community-Based Enhancement Program on Emergency Assistance and Marine Patient Transfer Coordination Competency Among Community Health Volunteers on the Remote Islands of Southern Thailand: Quasi-Experimental Study.","authors":"Praditporn Pongtriang, Chulalak Kaewsuk, Pilaiporn Sukcharoen, Aranya Rakhab","doi":"10.2196/80195","DOIUrl":"10.2196/80195","url":null,"abstract":"<p><strong>Background: </strong>Currently, remote areas face problems accessing health services. Although emergency medical systems have a policy of pushing more rapid response units into these communities, they still have not covered many areas due to the distance and the lack of a specific system that fits the community context. The resulting delays to medical treatment after accidents and emergency illnesses in these areas thus increase the risk of severe symptoms, disability, and subsequent death.</p><p><strong>Objective: </strong>This study examines the effectiveness of a community-based enhancement program for emergency assistance and marine patient transfer coordination among community health volunteers (CHVs) on Phaluay Island, southern Thailand.</p><p><strong>Methods: </strong>This quasi-experimental study followed a 1-group pretest or posttest design. The research sample consisted of 30 CHVs selected through nonrandom purposive sampling. The research instruments were demographic questionnaires, knowledge and skill measures of emergency assistance, and a competency assessment of marine patient transfer coordination. The data analysis employed descriptive statistics, repeated measures analysis of variance, and the Bonferroni test, with statistical significance set at P less than .05.</p><p><strong>Results: </strong>The results revealed that the average scores on emergency assistance and marine patient transfer coordination knowledge were significantly higher (P<.001) after training compared to before, specifically at weeks 1 and 30. The average scores on emergency assistance and marine patient transfer coordination skills in weeks 1 and 30 in the CHVs were significantly higher (P<.001). The CHVs' mean scores for emergency assistance and marine patient transfer coordination competency before (at week 1) and after training (at week 30) were significantly higher (P<.001).</p><p><strong>Conclusions: </strong>This research suggests that there is a need for policy advocacy by relevant agencies to further develop CHV competencies, which require continuous stimulation, monitoring, and reskilling to prepare these volunteers and other community members to respond effectively to emergencies in remote areas.</p>","PeriodicalId":55723,"journal":{"name":"AsianPacific Island Nursing Journal","volume":"10 ","pages":"e80195"},"PeriodicalIF":0.0,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13037761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147596381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complementary Therapies for Diabetic Foot Ulcer Healing Among Patients in Asia: Scoping Review.","authors":"A Dian Miranda Yusran P, Saldy Yusuf, Herlina Burhan, Muhammad Jufri Taming","doi":"10.2196/76301","DOIUrl":"10.2196/76301","url":null,"abstract":"<p><strong>Background: </strong>Diabetic foot ulcers (DFUs) are a severe complication of diabetes mellitus that can lead to amputation and mortality. Conventional treatments may be insufficient, leading to an interest in complementary therapies such as herbal medicine, acupuncture, maggot debridement therapy, and biological therapies. These approaches are widely used in Asia, yet their effectiveness and integration into clinical practice remain underexplored.</p><p><strong>Objective: </strong>The scoping review aimed to map the types of complementary therapies used for DFU healing in Asia and evaluate their reported effectiveness, implementation challenges, and opportunities for integration into conventional care.</p><p><strong>Methods: </strong>A scoping review was conducted using the PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses for Scoping Reviews) framework and the methodology of Arksey and O'Malley. Articles were sourced from the PubMed, Scopus, and ProQuest databases, covering studies published from 2014 to 2024. The population, concept, and context model guided the selection of studies, focusing on patients with DFUs, complementary therapies, and the Asian region.</p><p><strong>Results: </strong>Eight studies met the inclusion criteria. The most commonly used therapies included herbal treatments (eg, traditional Chinese medicinal foot soaks and Teucrium polium), biological therapies, including maggot debridement therapy and platelet-rich fibrin with hyaluronic acid), physical therapy (acupuncture), and psychological therapies (music therapy). Topical T polium significantly reduced wound size, and platelet-rich fibrin combined with hyaluronic acid increased vascular endothelial growth factor levels while reducing inflammation. Music therapy lowered the diabetes-related distress score. Despite these promising results, challenges remain, including a limited number of large-scale randomized controlled trials, regulatory barriers, and cultural perceptions affecting therapy acceptance.</p><p><strong>Conclusions: </strong>Complementary therapies are promising adjuncts for DFU management in Asia, where traditional medical practices are prevalent. Multidisciplinary collaboration between health care providers, policymakers, and traditional practitioners is essential for safe and effective integration. Further well-designed randomized controlled trials are required to confirm the efficacy of these therapies and inform evidence-based policies.</p>","PeriodicalId":55723,"journal":{"name":"AsianPacific Island Nursing Journal","volume":"10 ","pages":"e76301"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13002009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147488628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of BMI on Mortality in Patients With Tuberculosis and HIV Coinfection in Asia and Africa: Systematic Review and Meta-Analysis.","authors":"Mufti As Siddiq M Irzal, Tri Yunis Miko Wahyono, Putri Novia Choiri Insani, Welstin Wemi Loa, Leopardo Alvalius Ngetwa","doi":"10.2196/81905","DOIUrl":"10.2196/81905","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) continues to pose a major global health threat, particularly in low- and middle-income countries. An estimated 10.8 million people developed TB in 2023, corresponding to 134 cases per 100,000 population. The Southeast Asia region accounted for 45% of global TB incidence, while the African region contributed 24%. Nutritional status, particularly low BMI, is a key modifiable determinant of adverse clinical outcomes. However, its overall impact on mortality among TB-HIV coinfected populations in Asia and Africa remains poorly quantified.</p><p><strong>Objective: </strong>This study aimed to systematically assess the association between BMI and mortality among patients with TB-HIV coinfection in Asia and Africa.</p><p><strong>Methods: </strong>A systematic review and meta-analysis were conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 guidelines. Cohort studies published between 2000 and 2024 were identified through PubMed, Scopus, and ProQuest. Data extraction and risk of bias assessment were performed independently by 3 reviewers using the Risk of Bias in Non-Randomized Studies - of Exposure tool. A random effects model with the DerSimonian-Laird method was applied using RevMan 7.2 (Cochrane) to estimate pooled risk ratios with 95% CI. Heterogeneity was quantified using the I² statistic, and subgroup analyses were conducted by geographic region.</p><p><strong>Results: </strong>Seven cohort studies met the inclusion criteria. The pooled estimate indicated that patients with BMI less than 18.5 kg/m² had approximately twofold higher mortality risk compared to those with normal or higher BMI (risk ratio=2.01; 95% CI 1.63-2.48; P<.001). Despite moderate heterogeneity (I²=64%), the association remained consistent across subgroups. Although most studies were rated as having high or moderate risk of bias, sensitivity analyses confirmed the robustness of the results.</p><p><strong>Conclusions: </strong>Low BMI significantly increases the risk of mortality among patients with TB and HIV coinfection in Asia and Africa, underscoring its prognostic and modifiable role in clinical outcomes. Routine nutritional screening, BMI monitoring, and targeted supplementation should be integrated into national TB-HIV management programs, particularly in resource-limited settings. Strengthening TB-HIV nutrition service integration is essential to improve survival and achieve global End TB and United Nations Programme on HIV/AIDS 95-95-95 targets.</p>","PeriodicalId":55723,"journal":{"name":"AsianPacific Island Nursing Journal","volume":"10 ","pages":"e81905"},"PeriodicalIF":0.0,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12977329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147437861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cumulative High-Risk Pregnancy Complications and Stunting Risk in Indonesian Children Younger Than 5 Years: Retrospective Analysis Using the Developmental Origins of Health and Disease Framework.","authors":"Widyawati Widyawati, Hafifah Maulia Ristandiati","doi":"10.2196/85742","DOIUrl":"10.2196/85742","url":null,"abstract":"<p><strong>Background: </strong>Stunting affects 21.6% of Indonesian children younger than 5 years, with complications from high-risk pregnancies (HRPs) identified as a potential risk factor. The Developmental Origins of Health and Disease framework suggests that prenatal exposures may permanently alter physiological development and disease susceptibility later in life.</p><p><strong>Objective: </strong>This study aimed to examine the cumulative effects of HRP complications on the risk of stunting in Indonesian children younger than 5 years while controlling for socioeconomic confounders.</p><p><strong>Methods: </strong>A retrospective study was conducted in Sleman Regency, Indonesia, analyzing 450 children (300 children with stunting and 150 children without stunting) aged 12 to 59 months. Data were collected from maternal medical records, maternal and child health handbooks, and integrated health post reports. Multivariate logistic regression was used to adjust for socioeconomic confounders including maternal education, family income, and antenatal care (ANC) visits.</p><p><strong>Results: </strong>Mothers of children with stunting had significantly higher rates of any HRP complications (206/300, 68.7% vs 48/150, 32%; P<.001). After adjustment, multiple HRP complications (≥2 conditions) showed the strongest association with stunting (adjusted odds ratio [aOR] 5.80, 95% CI 3.26-10.32), exceeding the risk associated with individual complications such as anemia (aOR 3.21, 95% CI 2.12-4.86) or preeclampsia (aOR 4.37, 95% CI 2.18-8.76). Maternal education (aOR 0.72, 95% CI 0.58-0.89), family income (aOR 0.68, 95% CI 0.52-0.89), and ANC visits (aOR 0.85, 95% CI 0.76-0.95) were identified as protective factors.</p><p><strong>Conclusions: </strong>The dose-response relationship between cumulative HRP complications and stunting supports the Developmental Origins of Health and Disease hypothesis. Current ANC protocols emphasizing single risk factors may be insufficient. Integrated prenatal care addressing cumulative risks is essential for stunting prevention in Indonesia.</p>","PeriodicalId":55723,"journal":{"name":"AsianPacific Island Nursing Journal","volume":"10 ","pages":"e85742"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12945374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147312667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personal Agency Support Questionnaire in Acute Psychiatric Inpatients: Development and Instrument Validation Study.","authors":"Tomomi Kajiwara, Yuta Hayashi, Masami Sugihara, Rie Chiba","doi":"10.2196/83366","DOIUrl":"10.2196/83366","url":null,"abstract":"<p><strong>Background: </strong>Promoting personal agency may reduce perceived coercion and facilitate recovery in acute psychiatric care. However, no patient-reported tool currently exists to evaluate support for personal agency in this setting.</p><p><strong>Objective: </strong>This study aimed to develop a patient-reported tool (the Personal Agency Support Questionnaire [PASQ]) to assess perceived support for personal agency and to evaluate its psychometric properties among inpatients in acute psychiatric wards.</p><p><strong>Methods: </strong>We used a literature review and focus group interviews to generate a pool of items for the questionnaire, which was then refined using cognitive interviews and a pretest. We evaluated the construct validity, internal consistency, and test-retest reliability of the newly developed PASQ using a cross-sectional survey of inpatients in acute psychiatric wards. This study was conducted in collaboration with individuals who have lived experiences of mental illness.</p><p><strong>Results: </strong>We analyzed data from 109 respondents (response rate: 109/178, 61.2%; mean age: 52.9, SD 16.9 years; women participants: 59/109, 54.1%; diagnosed with schizophrenia: 61/109, 56%). The 10-item PASQ demonstrated excellent convergent validity and acceptable discriminant validity. Internal consistency was high (Cronbach α=0.92), and test-retest reliability was moderate (intraclass correlation coefficient 0.68).</p><p><strong>Conclusions: </strong>This PASQ is a valuable tool for assessing personal agency support in acute psychiatric wards, demonstrating promise for both clinical use in acute psychiatric wards and clinical research.</p>","PeriodicalId":55723,"journal":{"name":"AsianPacific Island Nursing Journal","volume":"10 ","pages":"e83366"},"PeriodicalIF":0.0,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12867469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146115204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cumulative High-Risk Pregnancy Complications and Stunting Risk in Indonesian Children Under Five: A DOHaD Framework Analysis.","authors":"Widyawati Widyawati, Hafifah Ristandiati","doi":"10.2196/85742","DOIUrl":"10.2196/85742","url":null,"abstract":"<p><strong>Background: </strong>Stunting affects 21.6% of Indonesian children under five, with complications from high-risk pregnancies (HRP) identified as a potential risk factor. The Developmental Origins of Health and Disease (DOHaD) framework suggests that prenatal exposures may permanently alter physiological development and disease susceptibility later in life.</p><p><strong>Objective: </strong>This study aimed to examine the cumulative effects of HRP complications on the risk of stunting in Indonesian children under five, while controlling for socioeconomic confounders.</p><p><strong>Methods: </strong>A retrospective study was conducted in Sleman Regency, Indonesia, analyzing 450 children (300 stunted and 150 non-stunted) aged 12-59 months. Data were collected from maternal medical records, Maternal and Child Health (MCH) handbooks, and integrated health post reports. Multivariate logistic regression was used to adjust for socioeconomic confounders including maternal education, family income, and antenatal care visits.</p><p><strong>Results: </strong>Mothers of stunted children had significantly higher rates of any HRP complication (68.7% vs. 32.0%, p < 0.001). After adjustment, multiple HRP complications (≥2 conditions) showed the strongest association with stunting (adjusted odds ratio [aOR]=5.80; 95% confidence interval [CI]: 3.26-10.32), exceeding the risk associated with individual complications such as anaemia (aOR=3.21; 95% CI: 2.12-4.86) or pre-eclampsia (aOR=4.37; 95% CI: 2.18-8.76). Maternal education (aOR = 0.72), family income (aOR = 0.68) and antenatal care visits (aOR = 0.85) were identified as protective factors.</p><p><strong>Conclusions: </strong>The dose-response relationship between cumulative HRP complications and stunting supports the DOHaD hypothesis. Current antenatal care protocols emphasizing single risk factors may be insufficient. Integrated prenatal care addressing cumulative risks is essential for stunting prevention in Indonesia.</p>","PeriodicalId":55723,"journal":{"name":"AsianPacific Island Nursing Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential Association of Inflammation With Pain and Physical Function in Knee Osteoarthritis by Race Focusing on Non-Hispanic Whites and Asian Americans: Pilot Study in Florida.","authors":"Chiyoung Lee, C Kent Kwoh, Hyochol Ahn","doi":"10.2196/75086","DOIUrl":"10.2196/75086","url":null,"abstract":"<p><strong>Background: </strong>The current body of work has not yet addressed the potential racial differences in the relationship between systemic inflammation and knee osteoarthritis (OA) symptoms, including pain and physical function.</p><p><strong>Objective: </strong>This pilot study aimed to investigate this association specifically among non-Hispanic Whites and Asian Americans.</p><p><strong>Methods: </strong>We cross-sectionally analyzed 40 community-dwelling participants aged 50-70 years with self-reported knee OA pain, including 20 non-Hispanic Whites and 20 Asian Americans. Knee OA symptoms were assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain and physical function subscales. The serum levels of C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α), and interleukin-10, as systemic inflammatory markers, were measured. Univariate and multivariable analyses, using stepwise linear regression models, were conducted to examine the correlation between these inflammatory markers and OA symptoms, with systematic adjustment for age.</p><p><strong>Results: </strong>In non-Hispanic Whites, the above inflammatory markers did not correlate with knee pain or physical function. In Asian Americans, bivariate analyses revealed that CRP and TNF-α levels were associated with worse WOMAC pain scores (r=1.325, P=.041; and r=2.418, P=.036, respectively), and CRP levels were also linked to worse WOMAC physical function scores (r=4.950, P=.035). Multivariate analyses confirmed the association of CRP levels with both worse WOMAC pain (β=1.328, P=.046) and physical function (β=4.974, P=.034) scores in Asian Americans.</p><p><strong>Conclusions: </strong>CRP may be a clinically relevant marker for knee OA symptoms, specifically in Asian Americans; however, caution is warranted owing to the exploratory nature of this study. Future research is set to benefit from leveraging a larger sample, incorporating additional inflammatory markers, and including racially diverse samples to validate and augment these findings.</p>","PeriodicalId":55723,"journal":{"name":"AsianPacific Island Nursing Journal","volume":"10 ","pages":"e75086"},"PeriodicalIF":0.0,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12798909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast Health Education as a Motivator for Breast Self-Examination Practice in High-Risk Women: Grounded Theory Analysis.","authors":"Sumaira Naz, Sureeporn Thanasilp, Wasinee Wisesrith","doi":"10.2196/83520","DOIUrl":"10.2196/83520","url":null,"abstract":"<p><strong>Background: </strong>Women in low-resource regions face a higher risk of breast cancer. Implementing a breast health initiative that promotes breast self-examination practice could aid in the early detection and prevention of breast cancer complications.</p><p><strong>Objective: </strong>This study aimed to explore and comprehend the experiences of high-risk women, focusing on their breast self-examination practice and the factors that influence their effectiveness in managing breast health.</p><p><strong>Methods: </strong>This research used a qualitative approach to perform semistructured interviews with 11 high-risk women who had a family history of breast cancer recruited from the oncology department of a hospital using purposive and theoretical sampling during the period from August 2024 to April 2025. The analysis of the data was conducted using the grounded theory approach by Strauss and Corbin to formulate a theoretical model for breast self-examination practices.</p><p><strong>Results: </strong>This study highlighted breast health education as a motivator of and the core category for breast self-examination practice. This study found perceptual, attitudinal, and familial support drivers of breast self-examination practice for early diagnosis of breast cancer and better living.</p><p><strong>Conclusions: </strong>This study enhances the body of knowledge regarding the experiences of high-risk women. Health care providers play a significant role in using this framework to steer innovative educational interventions that promote breast health in culture-bound communities.</p>","PeriodicalId":55723,"journal":{"name":"AsianPacific Island Nursing Journal","volume":"10 ","pages":"e83520"},"PeriodicalIF":0.0,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12798839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}