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American Journal of Geriatric Cardiology最新文献

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Coronary events in persons aged 75 years or older in Finland from 1995 to 2002: the FINAMI study. 1995 - 2002年芬兰75岁及以上人群的冠状动脉事件:FINAMI研究
American Journal of Geriatric Cardiology Pub Date : 2008-03-01
Heli Koukkunen, Veikko Salomaa, Seppo Lehto, Matti Ketonen, Pirjo Immonen-Räihä, Aapo Lehtonen, Aki Havulinna, Y Antero Kesäniemi, Kalevi Pyörälä
{"title":"Coronary events in persons aged 75 years or older in Finland from 1995 to 2002: the FINAMI study.","authors":"Heli Koukkunen,&nbsp;Veikko Salomaa,&nbsp;Seppo Lehto,&nbsp;Matti Ketonen,&nbsp;Pirjo Immonen-Räihä,&nbsp;Aapo Lehtonen,&nbsp;Aki Havulinna,&nbsp;Y Antero Kesäniemi,&nbsp;Kalevi Pyörälä","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors used population-based myocardial infarction (MI) register data to examine trends in incidence, case fatality, treatment strategies of MI, and coronary heart disease (CHD) mortality in persons aged 75 to 99 years in 4 areas of Finland during 1995 through 2002. This age group contributed 53% (n=13,977) of all CHD events, and 65% occurred in women. CHD mortality declined among men annually by 3.5% and 1.0% in the 75- to 84-year-old and 85- to 99-year-old age groups, respectively. Among women, it declined by 2.2% per year in the 75- to 84-year-old age group but increased by 1.3% per year in the 85- to 99-year-old age group. MI attack rate did not change in men but increased significantly in women aged 85 to 99 years. Clinical management of MI in elderly patients was more conservative than in middle-aged patients. In conclusion, one-half of all CHD events occur among persons aged 75 years or older, and elderly patients with CHD represent an increasing burden to the health care system.</p>","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"17 2","pages":"78-86"},"PeriodicalIF":0.0,"publicationDate":"2008-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27309982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomarkers, age, and coronary artery remodeling in patients with acute coronary syndrome. 急性冠状动脉综合征患者的生物标志物、年龄和冠状动脉重塑
American Journal of Geriatric Cardiology Pub Date : 2008-03-01
Dalin Song, Weiqiang Kang, Heribert Woelki, Mei Li, Xingui Guo
{"title":"Biomarkers, age, and coronary artery remodeling in patients with acute coronary syndrome.","authors":"Dalin Song,&nbsp;Weiqiang Kang,&nbsp;Heribert Woelki,&nbsp;Mei Li,&nbsp;Xingui Guo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To investigate the relationship between age and coronary artery remodeling in patients with acute coronary syndrome (ACS), 56 patients with ACS were identified by intravascular ultrasound (IVUS). Remodeling index (RI) (37 cases of RI > or =1 vs 19 cases of RI <1) and dimidiate age groups (27 patients younger than 60 years vs 29 patients 60 years or older) were compared, and the relationships among biomarkers, age, and arterial remodeling were analyzed. There was a significant difference in age between positive and negative remodeling groups (55+/-13 vs 62+/-10 years; P=.038); RI and triglyceride level showed a statistical correlation (r=0.32; P=.02) and a significant inverse correlation between age and RI (r=-0.47; P<.001). The multivariable linear regression analysis demonstrated that age was an independent predictor of RI (Bate -0.37; 95% confidence interval, 0.93-1.08; P=.04). Age may be an important factor of arterial remodeling. Low-density lipoprotein or triglyceride level may be associated with attenuated coronary vascular remodeling with aging.</p>","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"17 2","pages":"71-7"},"PeriodicalIF":0.0,"publicationDate":"2008-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27309279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Statins and heart failure. 他汀类药物和心力衰竭。
American Journal of Geriatric Cardiology Pub Date : 2008-03-01
Dennis L DeSilvey
{"title":"Statins and heart failure.","authors":"Dennis L DeSilvey","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"17 2","pages":"130-1"},"PeriodicalIF":0.0,"publicationDate":"2008-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27309975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrocardiographic intervals in the healthy geriatric population--what are the "normals"? 健康老年人群的心电图间隔——什么是“正常”?
American Journal of Geriatric Cardiology Pub Date : 2008-03-01
Latha G Stead, Lekshmi Vaidyanathan, Raquel M Schears, Rachel M Gilmore, Krishna C Vedula, Sandhya R Behera, M Fernanda Bellolio, Gerald T Gau, Wyatt W Decker
{"title":"Electrocardiographic intervals in the healthy geriatric population--what are the \"normals\"?","authors":"Latha G Stead,&nbsp;Lekshmi Vaidyanathan,&nbsp;Raquel M Schears,&nbsp;Rachel M Gilmore,&nbsp;Krishna C Vedula,&nbsp;Sandhya R Behera,&nbsp;M Fernanda Bellolio,&nbsp;Gerald T Gau,&nbsp;Wyatt W Decker","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors compared the average electrocardiographic (ECG) intervals in a population of patients 80 years and older with published \"normal\" values. The medical records of patients who presented to the Mayo Clinic for health maintenance examinations and who had a routine ECG performed (N=702) were selected. Age; sex; rhythm; PR, QRS, and QTc intervals; incidence of cardiac disease; and presence of interval-prolonging medication were recorded. Reference ranges were estimated from the data and compared with standard cutoffs for prolonged intervals. Interval values were significantly higher in men. Reference ranges were established separately for both sexes based on the subset of 578 patients without a history of cardiac disease and not taking interval-prolonging medication. In all instances, the ranges were higher than the recommended cutoffs. The upper limits for prolonged PR, QRS, and QTc intervals were found to be significantly higher in a population of patients older than 80 years.</p>","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"17 2","pages":"87-91"},"PeriodicalIF":0.0,"publicationDate":"2008-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27309277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of syncope in older adults may require thorough evaluation: a conversation with Dr. Mathew Maurer. 老年人晕厥的管理可能需要彻底的评估:与Mathew Maurer博士的对话。
American Journal of Geriatric Cardiology Pub Date : 2008-03-01
Ali Ahmed
{"title":"Management of syncope in older adults may require thorough evaluation: a conversation with Dr. Mathew Maurer.","authors":"Ali Ahmed","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"17 2","pages":"123-4"},"PeriodicalIF":0.0,"publicationDate":"2008-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27309973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monotherapy vs combination therapy for dyslipidemia in the elderly. 老年人血脂异常的单药vs联合治疗。
American Journal of Geriatric Cardiology Pub Date : 2008-03-01
James Shepherd
{"title":"Monotherapy vs combination therapy for dyslipidemia in the elderly.","authors":"James Shepherd","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Dyslipidemia conveys a major increased risk of future cardiovascular events in older persons. Data from large randomized controlled trials confirm that statin therapy is as beneficial in older adults as it is in younger persons in both primary and secondary prevention. National guidelines support the use of statin therapy to reduce low-density lipoprotein cholesterol in older adults, with the recommended goal of <100 mg/dL in high-risk patients and an optional goal of <70 mg/dL in very high-risk patients. In the majority of high-risk older patients, these levels of low-density lipoprotein cholesterol can be achieved with initial low doses of an efficacious statin, but in some clinical situations, combination therapy may be considered. Moreover, statins appear to be safe and well tolerated in older age groups. Because of heightened risks of drug-drug interactions, the likelihood of polypharmacy in seniors, and issues of tolerability and convenience, monotherapy with low doses of an efficacious statin may be preferable to combination therapy in elderly individuals.</p>","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"17 2","pages":"108-13"},"PeriodicalIF":0.0,"publicationDate":"2008-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27309979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethical Issues in the Management of Geriatric Cardiac PatientsHannah I. Lipman, MD, Section EditorFrom the Department of Medicine, Divisions of Geriatrics and Cardiology, Montefiore Medical Center of the Albert Einstein College of Medicine, Bronx, NY 老年心脏病患者管理中的伦理问题Hannah I.Lipman，医学博士，章节编辑来自纽约布朗克斯阿尔伯特·爱因斯坦医学院蒙蒂菲奥里医学中心老年医学和心脏病学部医学系
American Journal of Geriatric Cardiology Pub Date : 2008-02-14 DOI: 10.1111/j.1076-7460.2007.08147.x
Blair Holtey MDiv, Lofty Basta MD
{"title":"Ethical Issues in the Management of Geriatric Cardiac PatientsHannah I. Lipman, MD, Section EditorFrom the Department of Medicine, Divisions of Geriatrics and Cardiology, Montefiore Medical Center of the Albert Einstein College of Medicine, Bronx, NY","authors":"Blair Holtey MDiv,&nbsp;Lofty Basta MD","doi":"10.1111/j.1076-7460.2007.08147.x","DOIUrl":"https://doi.org/10.1111/j.1076-7460.2007.08147.x","url":null,"abstract":"<p> <b>\u0000 <i>Ethical Issue:</i>\u0000 </b>\u0000 <i>Participating physicians failed to properly document that the patient had no reasonable expectation of recovery. This caused a delay in the initiation of discussion concerning end-of-life.</i> </p>","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"17 1","pages":"48-49"},"PeriodicalIF":0.0,"publicationDate":"2008-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1076-7460.2007.08147.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71958055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and Safety of Fixed Combinations of Irbesartan/Hydrochlorothiazide in Older vs Younger Patients With Hypertension Uncontrolled With Monotherapy 厄贝沙坦/氢氯噻嗪固定联合治疗单药未控制的老年与年轻高血压患者的疗效和安全性
American Journal of Geriatric Cardiology Pub Date : 2008-02-14 DOI: 10.1111/j.1076-7460.2007.07317.x
William C. Cushman MD, Joel M. Neutel MD, Elijah Saunders MD, George L. Bakris MD, Keith C. Ferdinand MD, Elizabeth O. Ofili MD, James R. Sowers MD, Robert Madder DO, Michael A. Weber MD
{"title":"Efficacy and Safety of Fixed Combinations of Irbesartan/Hydrochlorothiazide in Older vs Younger Patients With Hypertension Uncontrolled With Monotherapy","authors":"William C. Cushman MD,&nbsp;Joel M. Neutel MD,&nbsp;Elijah Saunders MD,&nbsp;George L. Bakris MD,&nbsp;Keith C. Ferdinand MD,&nbsp;Elizabeth O. Ofili MD,&nbsp;James R. Sowers MD,&nbsp;Robert Madder DO,&nbsp;Michael A. Weber MD","doi":"10.1111/j.1076-7460.2007.07317.x","DOIUrl":"10.1111/j.1076-7460.2007.07317.x","url":null,"abstract":"<p> <b>\u0000 <i>Subgroup analysis of the Irbesartan/Hydrochlorothiazide Blood Pressure Reductions in Diverse Patient Populations (INCLUSIVE) trial evaluated the efficacy and safety of irbesartan/hydrochlorothiazide (HCTZ) fixed combinations in patients aged 65 years or older with uncontrolled systolic blood pressure (SBP) after ≥4 weeks of antihypertensive monotherapy. The INCLUSIVE trial was a prospective, open-label, single-arm trial carried out in 119 sites. Of 844 patients completing placebo treatment, 212 were aged 65 years or older. Participants received treatment with placebo (4–5 weeks), HCTZ 12.5 mg (2 weeks), irbesartan/HCTZ 150/12.5 mg (8 weeks), and then irbesartan/HCTZ 300/25 mg (8 weeks). From baseline to week 18 (n=184, intent-to-treat population), mean change in SBP was −23.0±13.3 mm Hg (</i>P<i>&lt;.001) and diastolic BP (DBP) was −10.9±7.7 mm Hg (</i>P<i>&lt;.001). Mean SBP/DBP at study end was 134.0±14.7/75.1±8.4 mm Hg, and SBP, DBP, and SBP/DBP goal was achieved in 73%, 96%, and 72% of patients, respectively. Irbesartan/HCTZ combination therapy allowed SBP goal attainment in 73% of patients aged 65 years or older whose hypertension was previously uncontrolled with antihypertensive monotherapy.</i></b> </p>","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"17 1","pages":"27-36"},"PeriodicalIF":0.0,"publicationDate":"2008-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1076-7460.2007.07317.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27205227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
High NT-proBNP Is a Strong Predictor of Outcome in Elderly Heart Failure Patients 高NT-proBNP是老年心力衰竭患者预后的有力预测因子
American Journal of Geriatric Cardiology Pub Date : 2008-02-14 DOI: 10.1111/j.1076-7460.2007.06674.x
Sven E. Andersson MD, PhD, Marie-Louise Edvinsson BSc, Jonas Björk PhD, Lars Edvinsson MD, PhD
{"title":"High NT-proBNP Is a Strong Predictor of Outcome in Elderly Heart Failure Patients","authors":"Sven E. Andersson MD, PhD,&nbsp;Marie-Louise Edvinsson BSc,&nbsp;Jonas Björk PhD,&nbsp;Lars Edvinsson MD, PhD","doi":"10.1111/j.1076-7460.2007.06674.x","DOIUrl":"10.1111/j.1076-7460.2007.06674.x","url":null,"abstract":"<p> <b>\u0000 <i>All patients older than 65 years (184 men; mean age, 78±0.8 years/181 women; mean age, 82±0.6 years) seeking medical attention at the Lund University Hospital Emergency Clinic during a 2-year period who had an N-terminal prohormone brain natriuretic peptide (NT-proBNP) value &gt;2000 pg/mL were followed up for survival. Mortality in the entire population was 21% after 3 months, 35% after 1 year, and 40% after 2 years. Multivariate analysis indicated that the NT-proBNP level and the New York Heart Association (NYHA) functional class were stronger predictors of mortality than were echocardiographic estimation of left ventricular ejection fraction or chest radiography. Patients who survived the first year were younger, had higher systolic blood pressure, had lower plasma creatinine, had lower inflammatory activity, and were treated with lower doses of furosemide. The results indicate that in this population, NT-proBNP level together with assessment of NYHA class gives the best prognostic information of 1-year mortality.</i>\u0000 </b> </p>","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"17 1","pages":"13-20"},"PeriodicalIF":0.0,"publicationDate":"2008-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1076-7460.2007.06674.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27205225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
Morphologic Features of Atherosclerotic Plaque in Occlusive Femoral Artery Disease Treated by Endarterectomy 动脉内膜切除术治疗股动脉闭塞性疾病动脉粥样硬化斑块的形态学特征
American Journal of Geriatric Cardiology Pub Date : 2008-02-14 DOI: 10.1111/j.1076-7460.2007.07672.x
William Clifford Roberts MD, Jong Mi Ko BA, Gregory John Pearl MD
{"title":"Morphologic Features of Atherosclerotic Plaque in Occlusive Femoral Artery Disease Treated by Endarterectomy","authors":"William Clifford Roberts MD,&nbsp;Jong Mi Ko BA,&nbsp;Gregory John Pearl MD","doi":"10.1111/j.1076-7460.2007.07672.x","DOIUrl":"10.1111/j.1076-7460.2007.07672.x","url":null,"abstract":"","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"17 1","pages":"50-52"},"PeriodicalIF":0.0,"publicationDate":"2008-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1076-7460.2007.07672.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27205780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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