American Journal of Geriatric Cardiology最新文献_第10页

Persistence of Treatment and Blood Pressure Control in Elderly Hypertensive Patients Treated With Different Classes of Antihypertensive Drugs 不同类型降压药治疗老年高血压患者的持续治疗及血压控制

American Journal of Geriatric Cardiology Pub Date : 2007-09-04 DOI: 10.1111/j.1076-7460.2007.06586.x

Claudio Borghi MD, Maddalena Veronesi MD, Ada Dormi MS, Maria Grazia Prandin MD, Eugenio Cosentino MD, Enrico Strocchi MD

{"title":"Persistence of Treatment and Blood Pressure Control in Elderly Hypertensive Patients Treated With Different Classes of Antihypertensive Drugs","authors":"Claudio Borghi MD, Maddalena Veronesi MD, Ada Dormi MS, Maria Grazia Prandin MD, Eugenio Cosentino MD, Enrico Strocchi MD","doi":"10.1111/j.1076-7460.2007.06586.x","DOIUrl":"10.1111/j.1076-7460.2007.06586.x","url":null,"abstract":" \u0000 Unsatisfactory blood pressure (BP) control in the treated hypertensive patient is largely related to poor compliance with antihypertensive drug regimens. The aim of the present study was to prospectively evaluate the rate of persistence on treatment and the extent of BP control in 301 elderly, uncomplicated grade I or II hypertensive patients randomly allocated to monotherapy with angiotensin-converting enzyme (ACE) inhibitors, calcium channel blockers (CCBs), β-blockers, angiotensin II receptors (ARBs), or diuretics according to an open-label single-blind study design. After 24 months, the percentage of patients continuing their initial therapy was higher in those treated with ARBs (68.5%) and ACE inhibitors (64.5%) and lower in patients taking diuretics (34.4%; P<.01). The logistic regression model using ARBs as reference term showed that patients treated with ACE inhibitors (odds ratio [OR], 0.94; 95% confidence interval [CI], 0.79–0.99) or CCBs (OR, 0.76; 95% CI, 0.54–0.85) were more likely to continue their initial antihypertensive therapy when compared with those treated with β-blockers (OR, 0.67; 95% CI, 0.57–0.79) or diuretics (OR, 0.56; 95% CI, 0.38–0.84). The average systolic and diastolic BP decrease was greater in patients treated with ARBs (−11.2±4/−5.8±2 mm Hg), ACE inhibitors (−10.5±4/−5.1±2 mm Hg), and CCBs (−8.5±3/−4.6±2 mm Hg) and lesser in those treated with diuretics (−2.3±4/−2.1±3 mm Hg, P<.05) and β-blockers (−4.0±2/−2.3±2 mm Hg; P<.05). The study confirms the importance of persistence with treatment for the effective management of hypertension in clinical practice. ","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"16 5","pages":"280-286"},"PeriodicalIF":0.0,"publicationDate":"2007-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1076-7460.2007.06586.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26975128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Multiorgan Vascular Event Due to Left Atrial Myxoma 左房黏液瘤所致多器官血管事件

American Journal of Geriatric Cardiology Pub Date : 2007-09-04 DOI: 10.1111/j.1076-7460.2007.05202.x

Hasan Ali Khan MD, Rashed Al-Hamdan MD, Adnan Al-Asousi MD, Aiad-Al Anzi MD

引用次数: 3

Stephen Scheidt, MD Stephen Scheidt，医学博士

American Journal of Geriatric Cardiology Pub Date : 2007-09-04 DOI: 10.1111/j.1076-7460.2007.07593.x

引用次数: 0

Drug Choice Affects Treatment Compliance and Blood Pressure Outcomes in Elderly Hypertensive Patients 药物选择影响老年高血压患者的治疗依从性和血压结局

American Journal of Geriatric Cardiology Pub Date : 2007-09-04 DOI: 10.1111/j.1076-7460.2007.06228.x

Michael A. Weber MD, Nanette K. Wenger MD

引用次数: 7

Risk of Anticoagulation for Atrial Fibrillation in the Elderly 老年人房颤抗凝治疗的风险

American Journal of Geriatric Cardiology Pub Date : 2007-09-04 DOI: 10.1111/j.1076-7460.2007.06207.x

Dennis L. DeSilvey MD

引用次数: 0

Heart Failure in Older Adults: A Conversation With Dr Michael Rich 老年人心力衰竭:与Michael Rich博士的对话

American Journal of Geriatric Cardiology Pub Date : 2007-07-10 DOI: 10.1111/j.1076-7460.2007.06603.x

Ali Ahmed MD, MPH, Michael W. Rich MD

引用次数: 0

American Journal of Geriatric Cardiology Pub Date : 2007-07-02 DOI: 10.1111/j.1076-7460.2007.05849.x

Glenn A. Hirsch MD, MHS, W. Patricia Ingkanisorn MD, Steven P. Schulman MD, Gary Gerstenblith MD, Christopher K. Dyke MD, Kenneth L. Rhoads MD, Richard Thompson PhD, Anthony H. Aletras PhD, Andrew E. Arai MD

{"title":"Age-Related Vascular Stiffness and Left Ventricular Size After Myocardial Infarction","authors":"Glenn A. Hirsch MD, MHS, W. Patricia Ingkanisorn MD, Steven P. Schulman MD, Gary Gerstenblith MD, Christopher K. Dyke MD, Kenneth L. Rhoads MD, Richard Thompson PhD, Anthony H. Aletras PhD, Andrew E. Arai MD","doi":"10.1111/j.1076-7460.2007.05849.x","DOIUrl":"10.1111/j.1076-7460.2007.05849.x","url":null,"abstract":" \u0000 Aortic stiffness increases with age and may contribute to adverse remodeling after myocardial infarction (MI). The authors examined whether vascular stiffness affects left ventricular (LV) size after MI using contrast-enhanced cardiac magnetic resonance imaging. Despite similar infarct sizes, patients aged 60 years or older (n=30) had a lower ejection fraction (42±15 vs 53±11%, P<.01) and greater end-systolic volume index (75±47 vs 44±18 mL/m2, P<.01) than younger patients (n=19). As infarct size increased, LV end-systolic volumes (P<.0001) and ejection fraction (P<.0001) in the older participants were progressively greater. Participants with greater aortic stiffness had greater end-systolic volume indices (P<.0001) and lower ejection fraction (P<.0001) with increasing infarct size. Using multivariate analysis, MI size (P<.001) and aortic distensibility (P=.02) were significant predictors of end-systolic volume index. Older patients have increased LV size after MI compared with younger patients, possibly related to age-related decreases in aortic distensibility affecting LV remodeling. ","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"16 4","pages":"222-228"},"PeriodicalIF":0.0,"publicationDate":"2007-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1076-7460.2007.05849.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26818739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Ethics Education 伦理教育

American Journal of Geriatric Cardiology Pub Date : 2007-07-02 DOI: 10.1111/j.1076-7460.2007.06201.x

Hannah I. Lipman MD

引用次数: 0

Heart Failure in the “Oldest Old”: Clinical and Echocardiographic Insights 心力衰竭在“最老的老人”:临床和超声心动图的见解

American Journal of Geriatric Cardiology Pub Date : 2007-07-02 DOI: 10.1111/j.1076-7460.2007.06211.x

Joseph L. Bouchard MD, Gerard P. Aurigemma MD, Robert J. Goldberg MD, John B. Fournier BA, Craig S. Vinch MD, Jeffrey C. Hill RDCS, Cynthia A. Ennis MD, Dennis A. Tighe MD, Theo E. Meyer MD, PhD

{"title":"Heart Failure in the “Oldest Old”: Clinical and Echocardiographic Insights","authors":"Joseph L. Bouchard MD, Gerard P. Aurigemma MD, Robert J. Goldberg MD, John B. Fournier BA, Craig S. Vinch MD, Jeffrey C. Hill RDCS, Cynthia A. Ennis MD, Dennis A. Tighe MD, Theo E. Meyer MD, PhD","doi":"10.1111/j.1076-7460.2007.06211.x","DOIUrl":"10.1111/j.1076-7460.2007.06211.x","url":null,"abstract":" \u0000 While the incidence and prevalence of heart failure (HF) increase markedly with age, few studies have included data on a large series of patients aged 85 years and older. Clinical and echocardiographic data from 533 patients admitted to a tertiary care hospital for acute HF were obtained. Data from the oldest old (≥85 years; n=252; mean age, 91.9±3.6 years) were compared with data from those aged 65 to 74 years (n=123; mean age, 70.1±2.8 years) and 75 to 84 years (n=158; mean age, 79.4±2.9 years). Echocardiographic data were consistent with hypertensive remodeling. The proportion of patients with HF and a preserved left ventricular ejection fraction was greatest in the oldest patients (61%) in comparison to patients aged 65 to 74 years (48%) and 75 to 84 years (48%). Approximately three-fourths of the oldest patients were women, and two-thirds of women had a left ventricular ejection fraction ≥50%.\u0000 ","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"16 4","pages":"236-242"},"PeriodicalIF":0.0,"publicationDate":"2007-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1076-7460.2007.06211.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26818737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Outcomes of Unexplained Syncope in the Elderly 老年人不明原因晕厥的结局

American Journal of Geriatric Cardiology Pub Date : 2007-07-02 DOI: 10.1111/j.1076-7460.2007.05825.x

Oleg Roussanov MD, Greta Estacio FNP, Maribeth Capuno ANP, Judith Hill FNP, Csaba Kovesdy MD, Nabil Jarmukli MD

{"title":"Outcomes of Unexplained Syncope in the Elderly","authors":"Oleg Roussanov MD, Greta Estacio FNP, Maribeth Capuno ANP, Judith Hill FNP, Csaba Kovesdy MD, Nabil Jarmukli MD","doi":"10.1111/j.1076-7460.2007.05825.x","DOIUrl":"10.1111/j.1076-7460.2007.05825.x","url":null,"abstract":" \u0000 The objective of this study was to determine whether syncope of unknown etiology (SUE) influences mortality in the elderly. Patients with SUE at 65 years or older were identified retrospectively and their outcomes were compared with an age-, sex-, and comorbidity-matched group of patients drawn from the same population. All-cause 3-year mortality was analyzed using the Kaplan-Meier method and the log-rank test. SUE was identified in 150 of 304 patients (49%) with syncope. Patients with SUE and controls experienced mortality rates (1/1000 person-years [95% confidence interval]) of 147.8 (112.6–193.9) and 153.4 (117.5–200.3), P=.7, respectively. Of all the recorded characteristics of SUE, only the inpatient status was associated with higher all-cause mortality (Cox model adjusted hazard ratio [95% confidence interval] of inpatients vs outpatients with SUE: 2.2 [1.1–4.1], P=.017). New-onset SUE is not an independent predictor of mortality in elderly patients. ","PeriodicalId":55533,"journal":{"name":"American Journal of Geriatric Cardiology","volume":"16 4","pages":"249-254"},"PeriodicalIF":0.0,"publicationDate":"2007-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1076-7460.2007.05825.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26818743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9