Lindsey Negrete, Amy Maduram, Mark Mullins, Judy Gadde
{"title":"What It Takes to Win a Teaching Award-Radiology Trailblazers, an <i>AJR</i> Podcast Series (Episode 1).","authors":"Lindsey Negrete, Amy Maduram, Mark Mullins, Judy Gadde","doi":"10.2214/AJR.25.33479","DOIUrl":"10.2214/AJR.25.33479","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2533479"},"PeriodicalIF":6.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Feasible to First-Line: Ultrasound Diagnosis of Malrotation and Volvulus.","authors":"Alexander J Towbin","doi":"10.2214/AJR.25.33391","DOIUrl":"10.2214/AJR.25.33391","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2533391"},"PeriodicalIF":6.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HaiThuy N Nguyen, Alexander M El-Ali, Dane Van Tassel, Catalina Le Cacheux, Andrew C Sher, Afsaneh Amirabadi, Marla B K Sammer, Xiaofan Huang, Monique Riemann, Kevin Wong, Jeffrey Tutman, Desi M Schiess, Oscar M Navarro, Cicero T Silva
{"title":"Diagnostic Performance of Ultrasound for Diagnosing Midgut Malrotation and Volvulus in Children: A Multiinstitutional Retrospective Review.","authors":"HaiThuy N Nguyen, Alexander M El-Ali, Dane Van Tassel, Catalina Le Cacheux, Andrew C Sher, Afsaneh Amirabadi, Marla B K Sammer, Xiaofan Huang, Monique Riemann, Kevin Wong, Jeffrey Tutman, Desi M Schiess, Oscar M Navarro, Cicero T Silva","doi":"10.2214/AJR.25.32660","DOIUrl":"10.2214/AJR.25.32660","url":null,"abstract":"<p><p><b>BACKGROUND</b>. The reported diagnostic performance of ultrasound (US) for midgut malrotation and volvulus varies. <b>OBJECTIVE</b>. The purpose of this study was to evaluate the diagnostic performance of US for midgut malrotation and volvulus separately and to assess individual sonographic signs for each diagnosis. <b>METHODS</b>. This multicenter, retrospective, cross-sectional study included children (who were defined as individuals 0-18 years old) who had US performed as the first imaging test for evaluation of suspected midgut malrotation or volvulus from January 1, 2018, to June 30, 2021. Clinical data were extracted from medical records. Blinded reviewers measured the proximal duodenum and assessed for malrotation and volvulus as well as for specific sonographic signs. Nondiagnostic and equivocal studies were excluded. The reference standards used for malrotation included surgery, upper gastrointestinal (UGI) series, and CT and/or MRI. Volvulus reference standards included the same plus clinical follow-up (minimum, 28 days). Sensitivity, specificity, and accuracy were calculated to evaluate diagnostic performance; the Wilcoxon rank sum test was used to compare median values. <b>RESULTS</b>. Malrotation analysis included 384 examinations; median patient age was 32 days (IQR, 5-182 days). Volvulus analysis included 900 examinations; median patient age was 60 days (IQR, 9-573 days). The sensitivity and specificity of US for malrotation were 93% (95% CI, 81-98%) and 96% (95% CI, 92-98%) by original report and 97% (95% CI, 87-100%) and 99% (95% CI, 97-100%) by blinded research review. The sensitivity and specificity of US for volvulus were 97% (95% CI, 85-100%) and 98% (95% CI, 96-99%) by original report and 97% (95% CI, 86-100%) and 99% (95% CI, 98-100%) by blinded research review. The most accurate sonographic signs were the intraperitoneal position of the third portion of the duodenum for malrotation (accuracy = 98%) and the whirlpool sign for volvulus (accuracy = 99%). The median proximal duodenal diameter was greater in children with volvulus (13 mm [IQR, 7-18 mm] versus 6 mm [IQR, 4-8 mm], <i>p</i> < .001). <b>CONCLUSION</b>. The performance of US for diagnosing both midgut malrotation and volvulus is excellent in the setting of a diagnostic imaging study. <b>CLINICAL IMPACT</b>. US can be used as the first-line imaging modality for diagnosing midgut malrotation and volvulus, with UGI series reserved for nondiagnostic or equivocal examinations.</p>","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2532660"},"PeriodicalIF":6.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sergio Valencia, Maria C Cortes-Albornoz, Suely Fazio Ferracioli, Harry Griffin, Jad S Husseini, Fedel Machado-Rivas, Teresa Victoria, Michael S Gee, Camilo Jaimes
{"title":"Gadopiclenol Versus Gadoterate Meglumine for Pediatric Brain MRI: An Intraindividual Comparison of Contrast Enhancement.","authors":"Sergio Valencia, Maria C Cortes-Albornoz, Suely Fazio Ferracioli, Harry Griffin, Jad S Husseini, Fedel Machado-Rivas, Teresa Victoria, Michael S Gee, Camilo Jaimes","doi":"10.2214/AJR.25.33201","DOIUrl":"10.2214/AJR.25.33201","url":null,"abstract":"<p><p><b>BACKGROUND</b>. The macrocyclic agent gadopiclenol, FDA-approved in 2022, has relatively high T1 relaxivity, allowing substantial dose reductions. <b>OBJECTIVE</b>. The purpose of this study was to perform an intraindividual quantitative and qualitative comparison of contrast enhancement between brain MRI examinations in pediatric patients performed using gadopiclenol (0.05 mmol/kg) and gadoterate meglumine (0.1 mmol/kg). <b>METHODS</b>. This retrospective study included 38 pediatric patients (mean age: 11.1 years; 25 male patients, 13 female patients) who underwent gadopiclenol-enhanced brain MRI (0.05 mmol/kg) from December 1, 2024, to March 31, 2025, and gadoterate meglumine-enhanced MRI (0.1 mmol/kg) within the prior 6 months using the same field strength and protocol. Data were separately analyzed for 3D T1-weighted (T1W) fast spin-echo (FSE), 3D T1W gradient-recalled echo (GRE), and 2D FLAIR postcontrast sequences (27, 11, and 22 patients, respectively). The contrast ratio (CR) and CNR were measured in physiologic enhancing structures (choroid plexus, pituitary, dural venous sinuses, turbinate mucosa). Two neuroradiologists identified a preferred sequence for characterizing enhancement of physiologic enhancing structures (choroid plexus, pituitary, dural venous sinuses, turbinate mucosa, dura mater) in side-by-side blinded comparisons using a Likert scale (-2 to 2). <b>RESULTS</b>. CR was higher for gadopiclenol than for gadoterate for the choroid plexus on 3D T1W FSE images (71.0 ± 17.8 vs 63.4 ± 37.2, <i>p</i> = .04) and turbinate on 3D T1W GRE images (81.7 ± 21.8 vs 58.1 ± 25.2, <i>p</i> = .01). The remaining comparisons of CR between the two agents were not significant (<i>p</i> > .05). The CNR was not significantly different between the two agents for any combination of structure and sequence (<i>p</i> > .05). Both readers, reader 1 (R1) and reader 2 (R2), preferred gadopiclenol on 3D T1W FSE images for the choroid plexus (R1 [mean score ± SD]: -0.4 ± 0.5, <i>p</i> = .005; R2: -0.5 ± 0.8, <i>p</i> = .02) and pituitary (R1: -0.5 ± 0.7, <i>p</i> < .001; R2: -0.5 ± 0.9, <i>p</i> = .009). R2 also preferred gadopiclenol on 3D T1W FSE images for the turbinate (mean score ± SD, -0.7 ± 0.7; <i>p</i> < .001). Both readers preferred gadoterate meglumine on FLAIR images for the turbinate (R1: 0.3 ± 0.5, <i>p</i> = .01; R2: 0.5 ± 0.8, <i>p</i> = .02). R2 also preferred gadoterate meglumine on FLAIR images for the choroid plexus (mean score ± SD, 0.5 ± 0.8; <i>p</i> = .01). Neither reader had a significant preference for either agent for the remaining combinations of structure and sequence (<i>p</i> > .05). <b>CONCLUSION</b>. The findings support use of gadopiclenol at half the standard gadolinium dose for pediatric brain MRI examinations. <b>CLINICAL IMPACT</b>. The use of gadopiclenol could facilitate reductions in cumulative gadolinium exposure in children requiring serial MRI examinations.</p>","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2533201"},"PeriodicalIF":6.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toward Global Standardization in Imaging Terminology for Cervical Cancer.","authors":"Takahiro Tsuboyama","doi":"10.2214/AJR.25.33419","DOIUrl":"10.2214/AJR.25.33419","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2533419"},"PeriodicalIF":6.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Detection to Survival: Strengthening the Case for Screening Mammography.","authors":"Derek L Nguyen","doi":"10.2214/AJR.25.33435","DOIUrl":"10.2214/AJR.25.33435","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2533435"},"PeriodicalIF":6.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Professional Pathways: Private Practice-Pediatric Imaging, an <i>AJR</i> Podcast Series (Episode 1).","authors":"Raisa Amiruddin, Shannon G Farmakis","doi":"10.2214/AJR.25.33521","DOIUrl":"10.2214/AJR.25.33521","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2533521"},"PeriodicalIF":6.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Judicious Use of Resting-State Functional MRI.","authors":"Shiori Amemiya","doi":"10.2214/AJR.25.33554","DOIUrl":"10.2214/AJR.25.33554","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2533554"},"PeriodicalIF":6.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Program Preference Signaling for the Dual Interventional Radiology and Diagnostic Radiology Residency Applicant.","authors":"Timothy M Cooke","doi":"10.2214/AJR.25.33049","DOIUrl":"10.2214/AJR.25.33049","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2533049"},"PeriodicalIF":6.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Saying the Same Thing: Why Terminology Matters in Multidisciplinary Cervical Cancer Care.","authors":"Surbhi Raichandani","doi":"10.2214/AJR.25.33449","DOIUrl":"10.2214/AJR.25.33449","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2533449"},"PeriodicalIF":6.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}