Jin Seong Kim, Ui Jae Hwang, Chang Woo Woo, Choong Hyeok Choi, Kyu Sung Chung
{"title":"Healing Integrity Determines Meniscal Extrusion After Isolated Medial Meniscus Posterior Root Repair in Knees With No Lower Limb Malalignment.","authors":"Jin Seong Kim, Ui Jae Hwang, Chang Woo Woo, Choong Hyeok Choi, Kyu Sung Chung","doi":"10.1002/arj.70337","DOIUrl":"10.1002/arj.70337","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate changes in meniscal extrusion and meniscal healing status following root repair, and the relationship between meniscal extrusion and healing conditions.</p><p><strong>Methods: </strong>Patients who underwent isolated root repair between 2019 and 2023 and consented to undergo second-look arthroscopy to evaluate their healing condition (1 year postoperatively) were included. The mean interval between root repair and second-look arthroscopy was 12.2 ± 1.3 months. The healing condition of the repaired meniscus was evaluated based on morphological continuity and meniscal tension at the bony attachment by probing (non-lax healing group, Group 1; lax healing group, Group 2). Meniscal extrusion was assessed in the coronal plane on magnetic resonance imaging preoperatively, immediately postoperatively, and at 1 year postoperatively. We analyzed the serial changes in meniscal extrusion according to the healing status observed during second-look arthroscopy.</p><p><strong>Results: </strong>A total of 51 patients were enrolled in the study (7 patients refused to undergo second-look arthroscopy, and 5 patients were lost to follow-up), with 30 assigned to Group 1 and 21 to Group 2. The mean age was 59.1 ± 6.2 years with 8 male and 43 female. Regarding postoperative clinical scores, the minimal clinically important difference (MCID) for Group 1 was as follows: Lysholm, 84.0 ± 7.4 (MCID: 3.55); WOMAC, 16.1 ± 8.1 (MCID: 4.67); and KOOS, 23.7 ± 6.6 (MCID: 5.69). Group 1 showed significantly better outcomes than Group 2, which had the following scores: Lysholm: 77.1 ± 7.8 (MCID: 3.78), WOMAC: 24.1 ± 9.2 (MCID: 4.41), and KOOS: 32.1 ± 9.2 (MCID: 6.03). All patients in both groups achieved the MCID for Lysholm, WOMAC, and KOOS (Group 1: 100% [30/30]; Group 2: 100% [21/21]). Immediately after surgery, meniscal extrusion decreased in both Group 1 (3.4 ± 0.8 to 2.0 ± 0.8) and Group 2 (3.2 ± 0.8 to 2.3 ± 0.8), with no significant difference between the groups. However, at the 1-year follow-up, extrusion increased again, with a greater increase observed in the lax healing group (2.8 ± 0.6 vs 4.5 ± 1.2, P < .001). Meniscal extrusion decreased by 0.6 ± 0.9 mm in the non-lax healing group, whereas it increased by 1.2 ± 1.3 mm in the lax healing group, showing a significant difference between the groups.</p><p><strong>Conclusions: </strong>These findings suggest that non-lax healing is associated with reduced meniscal extrusion postoperatively, whereas lax healing showed no such improvement. Differences in healing quality, as identified using second-look arthroscopy, appear to be closely associated with postoperative meniscal extrusion.</p><p><strong>Level of evidence: </strong>Level IV, retrospective case series.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":" ","pages":"2198-2210"},"PeriodicalIF":6.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147950303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vincent Tambosco, Vitor Ezequiel de Oliveira Neto, Angelo Mosca, Hervé Poilvache, Thais Dutra Vieira, Johannes Barth, Bertrand Sonnery-Cottet
{"title":"Anterior Cruciate Ligament Repair Shows Higher Failure Rate but Similar Functional Outcomes Compared With Reconstruction at 5 Years in Matched-Pair Analysis.","authors":"Vincent Tambosco, Vitor Ezequiel de Oliveira Neto, Angelo Mosca, Hervé Poilvache, Thais Dutra Vieira, Johannes Barth, Bertrand Sonnery-Cottet","doi":"10.1002/arj.70394","DOIUrl":"10.1002/arj.70394","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the 5-year outcomes of anterior cruciate ligament (ACL) repair versus ACL reconstruction in a matched cohort.</p><p><strong>Methods: </strong>Patients who underwent primary ACL repair or reconstruction between 2017 and 2019 were retrospectively analyzed. All surgical procedures were performed by two senior surgeons using standardized techniques. Patients were propensity matched 1:1 for age, sex, body mass index, time from injury to surgery, activity level, and preoperative pivot shift. Complications, reoperations, and patient-reported outcome measures (PROMs) including International Knee Documentation Committee, Lysholm, Knee injury and Osteoarthritis Outcome Score, ACL-Return to Sport after Injury, and Forgotten Joint Score-12 were evaluated at a minimum of 5 years.</p><p><strong>Results: </strong>Seventy-one matched pairs (142 patients) were included, mean follow-up was 6.3 ± 1.1 years [0.5-7.6] in the repair group and 6.4 ± 0.5 years [5.7-7.4] in the reconstruction group. The failure rate was significantly higher in the repair group (15.5%) compared with the reconstruction group (4.2%) (P = .032). Subgroup analysis showed that this difference was primarily observed in patients younger than 40 years (P = .037) and in those presenting with a preoperative pivot shift (P = .025), whereas no difference was found in patients older than 40 years (P = .99) and without preoperative pivot shift (P = .68). A significantly higher proportion of patients in the repair group achieved the Patient Acceptable Symptom State for Knee injury and Osteoarthritis Outcome Score symptoms compared with reconstruction patients (67.7% vs. 47.0%, P = .033). No significant differences in mean patient-reported outcome measures were found between groups at final follow-up.</p><p><strong>Conclusion: </strong>At midterm follow-up, ACL repair showed comparable functional outcomes but higher failure rates than reconstruction, particularly in younger or pivoting patients.</p><p><strong>Level of evidence: </strong>Level III, retrospective matched comparative study.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":" ","pages":"2232-2241"},"PeriodicalIF":6.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148334473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Commentary: Rotator Cuff Repair Augmentation: Arguably the Only Meaningful Improvement in Rotator Cuff Repair Outcomes in Last 40 Years, While Being Cost-Effective.","authors":"Ryan J Quigley, Krish S Sardesai, Brian J Cole","doi":"10.1002/arj.70344","DOIUrl":"10.1002/arj.70344","url":null,"abstract":"<p><p>Rotator cuff repair (RCR) remains one of the most commonly performed orthopaedic procedures and represents a dynamic scientific evolution. This progression toward optimizing patient outcomes has certainly been nonlinear, and it requires that we ask of ourselves: have advances in RCR delivered on this promise? Advances in surgical approach, repair configuration, and the introduction of marrow stimulation have produced largely equivalent outcomes, leaving retear rates persistently high, especially for large and massive tears. To that end, structural augmentation with allograft or xenograft has emerged as a notable exception, showing lower retear rates, improved functional outcomes, and structural integrity across multiple cohorts when compared with primary RCR alone. Despite a higher upfront cost and increased operative complexity, recent cost-effectiveness analyses affirm that allograft augmentation yields an incremental cost-effectiveness ratio within acceptable thresholds. This may challenge the philosophy that augmentation ought to be reserved only for revision or complex RCR. Xenograft, while cost-effective by some estimates, may represent a significantly higher complication profile without corresponding improvements in healing or function. The accumulating evidence positions allograft structural augmentation as arguably the only advancement in RCR that has delivered on the process of improving patient outcomes, and importantly, it does so while maintaining cost effectiveness.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":" ","pages":"1943-1945"},"PeriodicalIF":6.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Commentary: Results From Anterior Cruciate Ligament Repair Remain Inferior to Anterior Cruciate Ligament Reconstruction.","authors":"Robert D Bronstein","doi":"10.1002/arj.70435","DOIUrl":"10.1002/arj.70435","url":null,"abstract":"<p><p>Repair of the anterior cruciate ligament, long abandoned as ineffective, has shown a resurgence in interest as an alternative to reconstruction. The potential advantage of anterior cruciate ligament repair is preserving native ligament with potential proprioception retention and avoidance of autograft donor-site morbidity. The technique has been refined for proximal tears where the ligament can be brought back to the femoral footprint. Suture augmentation has been utilized by some surgeons, although an advantage of augmentation has not been proven. Overall, anterior cruciate ligament repair results have not approached the results of reconstruction, although some authors have reported comparable results in older patients with lower degrees of postinjury instability.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":" ","pages":"2242-2243"},"PeriodicalIF":6.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148363994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Commentary: Hip Microinstability: From Diagnostic Chaos to Clinical Precision.","authors":"Vikas Khanduja","doi":"10.1002/arj.70572","DOIUrl":"10.1002/arj.70572","url":null,"abstract":"<p><p>Hip microinstability is now widely accepted as a distinct clinical entity, yet consensus on how to diagnose it remains elusive. A current systematic review found 23 studies proposing 32 distinct diagnostic criteria across clinical history, physical examination, imaging, and intraoperative findings, evidence of a field still searching for a unified standard. Intraoperative ease of distraction, the most cited criterion, lacks reproducibility across surgeons and centers, whereas the hyperextension-external rotation test offers the most robust physical-examination data. Imaging markers like the femoroepiphyseal acetabular roof index, cliff sign, and capsular thinning on magnetic resonance imaging represent the strongest objective gains, though overlap with borderline dysplasia remains unresolved. Existing Delphi consensus frameworks provide structure but require prospective, multicenter validation. This commentary argues that the field must move beyond a binary diagnosis toward phenotypic characterization, stratifying patients by mechanical instability pattern rather than treating all cases identically, and calls for prospective, outcome-linked research to convert expert pattern recognition into evidence-based diagnostic certainty.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":" ","pages":"2321-2324"},"PeriodicalIF":6.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148834690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xinyu Tao, Teddy Cheong, Danyal H Nawabi, Hamid Rahmatullah Bin Abd Razak, Merrill Lee Jian Hui
{"title":"Labral Reconstruction of the Hip Provides Moderate Return to Sports for the Treatment of Labral Tears: A Systematic Review.","authors":"Xinyu Tao, Teddy Cheong, Danyal H Nawabi, Hamid Rahmatullah Bin Abd Razak, Merrill Lee Jian Hui","doi":"10.1002/arj.70514","DOIUrl":"https://doi.org/10.1002/arj.70514","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the rate of return to sport (RTS) and improvement in patient-reported outcomes after labral reconstruction in patients with labral tear.</p><p><strong>Methods: </strong>Major databases such as PubMed, Embase, Cumulative Index to Nursing and Allied Health, Scopus, and Cochrane Library were searched from inception to May 2025. Case series or cohort studies assessing outcomes and RTS rates after labral reconstruction were included. Literature retrieval and data extraction were conducted by 2 independent reviewers. Inclusion criteria were published prospective/retrospective studies or case series on patients diagnosed with hip labral tear undergoing labral reconstruction. Exclusion criteria were studies on patients who did not undergo labral reconstruction of the hip and non-English studies. Data analysis of modified Harris Hip Score, Non-Arthritic Hip Score, Hip Outcome Score, and Visual Analog Scale was conducted. RTS rates were analyzed.</p><p><strong>Results: </strong>Eight studies (2 case series, 6 cohort studies) involving 262 patients were included. The mean population age was 33 years, ranging from 10 to 40. Studies had RTS rates ranging from 64% to 88%. Four of these studies reported patients returning to sport at the same or an even higher level of play. Patient-reported outcomes improved postoperatively. Visual Analog Scale at the latest follow-up showed an improvement ranging from 2.60 to 4.50, with at least 70% of patients in 2 included studies achieving minimal clinically important difference and substantial clinical benefit. The modified Harris Hip Score improvement at the latest follow-up ranged from 18.00 to 24.30, with at least 60% of patients in included studies achieving minimal clinically important difference. Non-Arthritic Hip Score improvement at the latest follow-up ranged from 15.50 to 25.70, with 70% of participants in 1 study achieving minimal clinically important difference. Hip Outcome Score improvement at the latest follow-up ranged from 25.10 to 35.50. Three studies reported revision surgery rates ranging from 3.4% to 10%.</p><p><strong>Conclusions: </strong>Current evidence suggests that labral reconstruction for the treatment of hip labral tears is an effective option producing good RTS rates ranging from 60% to 80% and improvements in patient-reported outcomes.</p><p><strong>Level of evidence: </strong>Level IV, systematic review of Level III and IV studies.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":" ","pages":""},"PeriodicalIF":6.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149118795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhi-Dong Zhao, Kang-Kang Yu, Yan-Peng Zhao, Zhi-Jiang Li, Hua-Yi Gao, Zheng Guo, Yu-Xing Wang, Zhong-Li Li, Ming-Yang An, Chun-Bao Li
{"title":"Intervention Window for Knee Posttraumatic Osteoarthritis Appears as Early as 1 Week Post Anterior Cruciate Ligament Injury With Macrophage and Osteoclast as Potential Therapeutic Targets in a Rat Model.","authors":"Zhi-Dong Zhao, Kang-Kang Yu, Yan-Peng Zhao, Zhi-Jiang Li, Hua-Yi Gao, Zheng Guo, Yu-Xing Wang, Zhong-Li Li, Ming-Yang An, Chun-Bao Li","doi":"10.1002/arj.70151","DOIUrl":"10.1002/arj.70151","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the timing of initiating early intervention and potential therapeutic targets for posttraumatic osteoarthritis (PTOA) by characterizing the pathologic trajectory changes in an anterior cruciate ligament transection (ACLT)-induced rat PTOA model.</p><p><strong>Methods: </strong>Forty-eight healthy male Sprague-Dawley rats were used to establish the PTOA rat model. Rat knee specimens were collected consecutively at days 1, 3, 7, 10, 14, 21, 28, and 35 after ACLT (n = 6). The macroscopic morphology was evaluated by hematoxylin and eosin staining and three dimensional reconstructed micro-computed tomography images. Synovial inflammation was evaluated by F4/80 immunohistochemistry, myeloperoxidase staining, and immunofluorescent staining of CD206 and iNOS. Cartilage degradation was evaluated by immunohistochemistry staining with safranin O/fast green and MMP13. Subchondral bone remodeling was evaluated by micro-computed tomography and semiquantitative analysis of the ratio of bone volume over tissue volume, trabecular separation, and subchondral bone plate thickness. The cellular dynamics involved in subchondral remodeling were evaluated by staining with tartrate-resistant acid phosphatase, cathepsin K, and Osterix and receptor activator of nuclear factor kappa-B ligand. The specimens were then evaluated by 3 blinded observers using the Osteoarthritis Research Society International scoring systems.</p><p><strong>Results: </strong>Rat knee joint exhibited detectable changes in macroscopic appearance from day 7 after ACLT. Neutrophils infiltrated the synovium rapidly, peaking at day 1 after ACLT and significantly decreasing from day 3. Macrophage infiltration displayed 2 distinct waves at days 7 (principally M1) and 14 (principally M2). The osteoclast activity significantly increased from day 3 after ACLT. From days 7 to 35, increasing cartilage degradation occurred with simultaneous subchondral bone remodeling.</p><p><strong>Conclusions: </strong>Intervention window for PTOA appears as early as 1 week with macrophage in the synovium and osteoclast in the subchondral bone as potential therapeutic targets.</p><p><strong>Clinical relevance: </strong>Earlier advancement of the intervention time window (1 week) for clinical PTOA may be required, taking macrophages and osteoclasts as potential therapeutic targets, while the specific timepoints need further elucidation.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":" ","pages":"2173-2183"},"PeriodicalIF":6.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147576643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rebekah M Deardurff, Edward S Grood, Joseph Nolan, Frank R Noyes
{"title":"Injuries to Multiple Ligamentous and Capsular Structures Cause Abnormal Knee Hyperextension: A Robotic Study in Human Knees.","authors":"Rebekah M Deardurff, Edward S Grood, Joseph Nolan, Frank R Noyes","doi":"10.1002/arj.70319","DOIUrl":"10.1002/arj.70319","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the relationship of multiple ligamentous and capsular structures that may be injured in multidirectional knee injuries with abnormal knee hyperextension.</p><p><strong>Methods: </strong>A 6-degree-of-freedom robotic system measured intact motion limits and increases in knee hyperextension under extension loading up to 25 Nm and 25 N compression with selective tissue sectioning in 23 cadaveric knees. Two cutting sequences for sectioning ligamentous and capsular structures were used to simulate knee injuries with combined anterior cruciate ligament (ACL) disruption, posterolateral injury (lateral collateral ligament + popliteus tendon [LCL + POP]), and posterolateral and posteromedial capsular structures (PLC, PMC). The first cutting sequence sectioned the posterior capsular structures (OPL, PLC + FFL, PMC + POL) followed by the LCL + POP and ACL. The second cutting sequence simulated a common combined posterolateral and ACL injury followed by the posterior capsule (OPL, PLC + FFL, and PMC + POL).</p><p><strong>Results: </strong>Posterior capsule (OPL, PLC + FFL, and PMC + POL) disruption in sequence 1 is not associated with major increases in knee hyperextension (2.6° ± 1.0°, P < .01). Additional injury to the LCL + POP produces major hyperextension (4.5° ± 2.1°, P < .01). In sequence 2, disruption of the posterolateral complex (LCL + POP) and ACL is not associated with major increases in knee hyperextension (2.2° ± 1.0°, P < .01). Major increases in hyperextension occur after injury to the LCL + POP, ACL, and OPL (3.1° ± 1.6°, P < .01).</p><p><strong>Conclusions: </strong>Multidirectional ligament injury requires injury to 3 major capsular and ligamentous structures for a major abnormal increase in knee hyperextension. The results show the importance of the posteromedial and posterolateral capsules in limiting abnormal knee hyperextension, important for diagnosis and treatment considerations. Major increases in knee hyperextension occur with an intact, uninjured ACL when there is a disruption of the posteromedial and posterolateral capsule and posterolateral damage (LCL + POP).</p><p><strong>Clinical relevance: </strong>This study shows the role of multiple ligamentous and capsular structures providing stability to the knee joint and resisting abnormal knee hyperextension.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":" ","pages":"2130-2139"},"PeriodicalIF":6.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Commentary: The First Week Matters: Rethinking the Prophylaxis Window of Post-Traumatic Osteoarthritis for Post-Traumatic Knee Osteoarthritis After Anterior Cruciate Ligament Injury.","authors":"Junjie Xu","doi":"10.1002/arj.70355","DOIUrl":"10.1002/arj.70355","url":null,"abstract":"<p><p>The management of post-traumatic osteoarthritis is fundamentally hampered by a reactive paradigm, where treatment is initiated only after irreversible structural damage becomes clinically apparent. This approach overlooks the critical early molecular and cellular cascades triggered at the moment of joint injury. A strategic shift toward pre-emptive, disease-modifying intervention is imperative, necessitating a precise understanding of the initial postinjury timeline and the key cellular mediators driving joint degeneration. The absence of a clearly defined early therapeutic window and validated mechanistic targets remains one of the greatest barriers to effective joint preservation after anterior cruciate ligament injury. There is a preclinical report now showing that the pathological sequence leading to post-traumatic osteoarthritis is engaged within days, not months, following traumatic joint instability. These data redefine the acute therapeutic window and position synovial macrophages and subchondral osteoclasts as primary, actionable cellular targets for early disease interception. The future of post-traumatic osteoarthritis prevention lies in translating this detailed biological map into timed, targeted clinical strategies aimed at halting the disease process before it becomes clinically entrenched. Notably, it is essential to acknowledge that the results necessitate a more meticulous and judicious interpretation due to limitations specific to preclinical models before extensive clinical application.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":" ","pages":"2184-2185"},"PeriodicalIF":6.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147950249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rise in Delphi Studies Benefits Arthroscopists, Patients, and Arthroscopy Readers With Current Expert Consensus.","authors":"Matthew Salzler, Michael J Rossi","doi":"10.1002/arj.70642","DOIUrl":"10.1002/arj.70642","url":null,"abstract":"<p><p>Delphi Expert Consensus studies are increasingly common in orthopaedic literature and provide clinical guidance on many new and controversial topics. Although meta-analyses and randomized controlled trials remain the gold standard of evidence, they are not always feasible, not always definitive, and not always needed. Delphi Consensus Statements currently play a unique role in our research armamentarium to add insight to the many unanswered questions in arthroscopic surgery and sports medicine that other higher levels of evidence studies have not yet fully answered. Arthroscopy has been intentional in the past decade with our published Delphi articles that have offered compelling guidance in the diagnosis, imaging, and management of multiple pathologies in the knee, shoulder, hip, and elbow and in many sports medicine topics.</p>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":" ","pages":"1901-1906"},"PeriodicalIF":6.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148914497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}