Zixuan Luo , Jiawei Hu , Deguang Kong , Junlong Song, Zhiyu Li, Chuang Chen
{"title":"Mammographic microcalcifications as a predictor of neoadjuvant efficacy across different breast cancer molecular subtypes","authors":"Zixuan Luo , Jiawei Hu , Deguang Kong , Junlong Song, Zhiyu Li, Chuang Chen","doi":"10.1016/j.asjsur.2024.12.023","DOIUrl":"10.1016/j.asjsur.2024.12.023","url":null,"abstract":"<div><h3>Introduction</h3><div>Microcalcifications are significant indicators of breast cancer, particularly for distinguishing the different molecular subtypes. This study aimed to investigate the relationship between microcalcifications detected before treatment and various clinical indicators across different molecular types in breast cancer patients undergoing neoadjuvant chemotherapy (NAC).</div></div><div><h3>Methods</h3><div>In this retrospective study, clinical data from 178 breast cancer patients who underwent NAC, and 369 cases total, were analyzed. The patients were categorized into microcalcification and non-microcalcification groups according to mammography results. Statistical methods, including chi-square tests, t-tests, and nonparametric tests, were used to compare clinical variables across different molecular subtypes in the presence and absence of microcalcifications. Additionally, multivariate analyses and regression equations were used to determine the ability of microcalcifications to predict HER2-positive breast cancer.</div></div><div><h3>Results</h3><div>Significant differences were identified between breast cancer subtypes (X<sup>2</sup> = 14.129, <em>p</em> < 0.001) and type of breast surgery (X<sup>2</sup> = 5.073, <em>p</em> = 0.024). Patients with breast microcalcifications demonstrated a higher likelihood of achieving pathologic complete response (pCR) than those without microcalcifications (<em>p</em> = 0.041), particularly with the HER2-positive subtype, <em>p</em> = 0.004, odd ratio (OR) = 0.115, 95.0 % confidence interval (CI): 0.026–0.498). Conversely, patients with the basal-like subtype exhibited the opposite trend (<em>p</em> = 0.002, OR = 15.000, 95.0 % CI: 2.782–80.867). The results obtained from residual cancer burden (RCB) analysis were consistent with the pCR findings. Patients with the HER2-positive subtype exhibited the highest likelihood of developing breast microcalcifications (X<sup>2</sup> = 14.129, <em>p</em> < 0.001). We employed a logistic regression equation to predict the probability of achieving pCR in HER2-positive breast cancer and achieved an overall prediction accuracy of 82.72 %.</div></div><div><h3>Conclusions</h3><div>Breast microcalcifications are valuable predictors of NAC effectiveness, particularly with respect to molecular subtypes. Microcalcifications are associated with higher pCR rates and a lower RCB in HER2-positive breast cancer, but may reduce NAC efficacy in basal-like breast cancer. The predictive value of breast microcalcifications for NAC efficacy has crucial clinical implications for the treatment of HER2-positive breast cancer.</div></div>","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":"48 5","pages":"Pages 2902-2910"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143906185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wentian Xiao , Liuhanghang Cheng , Sally Ng , Hua Li , Shaoqing Feng , Yixin Zhang , Peiru Min
{"title":"Achieving ideal surgical outcomes by identifying the dominant supratrochlear artery for forehead flap harvesting: A comparative study","authors":"Wentian Xiao , Liuhanghang Cheng , Sally Ng , Hua Li , Shaoqing Feng , Yixin Zhang , Peiru Min","doi":"10.1016/j.asjsur.2024.11.165","DOIUrl":"10.1016/j.asjsur.2024.11.165","url":null,"abstract":"<div><h3>Background</h3><div>Despite being considered the golden standard for nasal reconstruction for decades, there has been a lack of detailed investigation into the hemodynamic differences between bilateral supratrochlear vessels during forehead flap procedures. In this study, the authors utilized infrared thermography (IRT) to identify the dominant supratrochlear vessel as the nourished pedicle, aiming to achieve optimal surgical outcomes.</div></div><div><h3>Methods</h3><div>A total of 24 regular and 40 pre-expanded forehead flaps, consecutively included from October 2017 to February 2023, were retrospectively divided into two groups for analysis. In group A (11 regular and 23 pre-expanded flaps), bilateral supratrochlear arteries were identified using infrared thermography (IRT) and color Doppler ultrasound (CDU), with the flap designed based on the dominant side. In group B (13 regular and 17 pre-expanded flaps), the flap was designed directly at the ipsilateral side. Vascular disparities and surgical outcomes were compared.</div></div><div><h3>Results</h3><div>Among the 34 flaps in group A, bilateral hemodynamic disparities were observed in 13 flaps (38.2 %), comprising of 3 regular flaps (27.2 %) and 10 pre-expanded flaps (43.5 %). The complication incidences for group A is lower than that for group B (5/34 VS 9/30, p < 0.05). The complication rate between regular and pre-expanded flaps was 3/24 versus 11/40, p < 0.05. All complications resulted in a delayed pedicle division.</div></div><div><h3>Conclusion</h3><div>The potential asymmetry of supratrochlear arteries could significantly impact the prognosis of nasal reconstruction with forehead flaps, especially within tissue expansion technique. It is essential to identify the dominant side to achieve optimized surgical outcomes.</div></div>","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":"48 5","pages":"Pages 2911-2917"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143906186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peirong Tian, Boyu Tao, Mengyi Li, Yang Liu, Jingli Liu, Jia Liu, Peng Zhang, Zhongtao Zhang, Chinese College of Metabolic and Bariatric Surgeons and Beijing Quality Control and Improvement Center of Metabolic and Bariatric Surgery
{"title":"Expert consensus on the clinical practice of sleeve gastrectomy in China using the modified Delphi method","authors":"Peirong Tian, Boyu Tao, Mengyi Li, Yang Liu, Jingli Liu, Jia Liu, Peng Zhang, Zhongtao Zhang, Chinese College of Metabolic and Bariatric Surgeons and Beijing Quality Control and Improvement Center of Metabolic and Bariatric Surgery","doi":"10.1016/j.asjsur.2024.11.211","DOIUrl":"10.1016/j.asjsur.2024.11.211","url":null,"abstract":"<div><h3>Background</h3><div>Sleeve gastrectomy (SG) is the most commonly performed bariatric surgery worldwide, including in China. Despite its prevalence, significant variations exist in its practice. This consensus aims to standardize SG practices in China.</div></div><div><h3>Methods</h3><div>A modified Delphi method was employed to gather expert opinions from 50 Chinese bariatric surgeons. Participants voted on 80 statements covering indications, contraindications, preoperative/postoperative management, and surgical techniques.</div></div><div><h3>Results</h3><div>Consensus was achieved on 54 out of 80 statements. Key areas include SG being the preferred choice for patients with high surgical risk and severe obesity. Agreement was reached on surgical techniques such as staple line reinforcement and the management of hiatal hernias found during surgery. Consensus was also achieved on aspects of preoperative and postoperative care, including routine endoscopy and the use of the enhanced recovery after surgery (ERAS) protocol.</div></div><div><h3>Conclusions</h3><div>This consensus provides valuable guidelines for standardizing SG practices in China. It provides evidence-based recommendations to standardize SG practice, improve outcomes, and guide future research directions.</div></div>","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":"48 5","pages":"Pages 2918-2926"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143906187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Navicular impingement syndrome of the wrist: A case report","authors":"Tao Guo , Hao Liu , Wendong Xie, Meng Li","doi":"10.1016/j.asjsur.2024.04.188","DOIUrl":"10.1016/j.asjsur.2024.04.188","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":"48 5","pages":"Pages 2940-2942"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141042946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Elevated expression of BTLA predicts poor prognosis and is associated with immune infiltration in glioma","authors":"Dongjie Zhou , Lirui Dai , Ao Shen, Peizhi Zhou","doi":"10.1016/j.asjsur.2024.11.074","DOIUrl":"10.1016/j.asjsur.2024.11.074","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":"48 5","pages":"Pages 3113-3114"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chao Wang , Shanshan Zhu , Qingyan Zhao, Zhonglu Chang
{"title":"Fontus stent treatment for aberrant right subclavian artery combined with the type A aortic dissection: A case report","authors":"Chao Wang , Shanshan Zhu , Qingyan Zhao, Zhonglu Chang","doi":"10.1016/j.asjsur.2024.11.081","DOIUrl":"10.1016/j.asjsur.2024.11.081","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":"48 5","pages":"Pages 3128-3129"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142820181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peng-Xia Ren, Suo-Yin Yan, Zhen-Zhen Zhang, Xin Li
{"title":"The effect of mind mapping-guided seamless operating room nursing on intraoperative complications in patients with uterine fibroids","authors":"Peng-Xia Ren, Suo-Yin Yan, Zhen-Zhen Zhang, Xin Li","doi":"10.1016/j.asjsur.2024.11.069","DOIUrl":"10.1016/j.asjsur.2024.11.069","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":"48 5","pages":"Pages 3066-3067"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasound manifestations of Kimura disease: A case report and literature review","authors":"Weixu Zhao , Jun Wu, Jianyuan Xuan","doi":"10.1016/j.asjsur.2024.11.203","DOIUrl":"10.1016/j.asjsur.2024.11.203","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":"48 5","pages":"Pages 3020-3021"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143906181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}